메뉴 건너뛰기




Volumn 240, Issue 3, 1996, Pages 518-525

Cloning and biochemical characterisation of an Aspergillus niger glucokinase. Evidence for the presence of separate glucokinase and hexokinase enzymes

Author keywords

Aspergillus niger; Dye affinity chromatography; Glucokinase; Hexokinase; Trehalose 6 phosphate

Indexed keywords

GLUCOKINASE; HEXOKINASE;

EID: 0029766086     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1996.0518h.x     Document Type: Article
Times cited : (32)

References (57)
  • 1
    • 0024212904 scopus 로고
    • Structure of yeast gluckinase, a strongly diverged specific aldohexose phosphorylating enzyme
    • Albig, W. & Entian, K. D. (1988) Structure of yeast gluckinase, a strongly diverged specific aldohexose phosphorylating enzyme, Gene (Amst.) 73, 141-152.
    • (1988) Gene (Amst.) , vol.73 , pp. 141-152
    • Albig, W.1    Entian, K.D.2
  • 3
    • 0025218127 scopus 로고
    • Glucose phosphorylation in tumor cells: Cloning sequencing and over-expression in active form of a full-length cDNA encoding a mitochondrially bindable form of hexokinase
    • Arora, K. K., Fanciulli, M. & Pedersen, P. L. (1990) Glucose phosphorylation in tumor cells: cloning sequencing and over-expression in active form of a full-length cDNA encoding a mitochondrially bindable form of hexokinase, J. Biol. Chem. 265, 6481-6488.
    • (1990) J. Biol. Chem. , vol.265 , pp. 6481-6488
    • Arora, K.K.1    Fanciulli, M.2    Pedersen, P.L.3
  • 4
    • 0017277818 scopus 로고
    • Assay of proteins in the presence of interfering materials
    • Bensadoun, A. & Weinstein, D. (1976) Assay of proteins in the presence of interfering materials, Anal. Biochem. 70, 241-250.
    • (1976) Anal. Biochem. , vol.70 , pp. 241-250
    • Bensadoun, A.1    Weinstein, D.2
  • 5
    • 0027305174 scopus 로고
    • Trehalose-6-phosphate, a new regulator of yeast glycolysis that inhibits hexokinases
    • Blázquez, M. A., Lagunas, R., Gancedo, C. & Gancedo, J. M. (1993) Trehalose-6-phosphate, a new regulator of yeast glycolysis that inhibits hexokinases, FEBS Lett. 329, 51-54.
    • (1993) FEBS Lett. , vol.329 , pp. 51-54
    • Blázquez, M.A.1    Lagunas, R.2    Gancedo, C.3    Gancedo, J.M.4
  • 6
    • 50549159930 scopus 로고
    • The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations
    • Cleland, W. W. (1963) The kinetics of enzyme-catalyzed reactions with two or more substrates or products. I. Nomenclature and rate equations, Biochim. Biophys. Acta 67, 104-137.
    • (1963) Biochim. Biophys. Acta , vol.67 , pp. 104-137
    • Cleland, W.W.1
  • 7
    • 2242461686 scopus 로고
    • The hexokinases
    • (Boyer, P. D., ed.) Academic Press, New York and London
    • Colowick, S. P. (1973) The hexokinases, in The enzymes (Boyer, P. D., ed.) vol. 9, pp. 1-48, Academic Press, New York and London.
    • (1973) The Enzymes , vol.9 , pp. 1-48
    • Colowick, S.P.1
  • 8
    • 0028140060 scopus 로고
    • Two different adjacent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline cluster of Aspergillus nidulans
    • Cubero, B. & Schazzocchio, C. (1994) Two different adjacent zinc finger binding sites are necessary for CREA-mediated carbon catabolite repression in the proline cluster of Aspergillus nidulans, EMBO J. 13, 407-415.
    • (1994) EMBO J. , vol.13 , pp. 407-415
    • Cubero, B.1    Schazzocchio, C.2
  • 9
    • 0029320068 scopus 로고
    • Arabidopsis thalania hexokinase cDNA isolated by complementation of yeast cells
    • Dai, A., Schaffer, A. A., Petreikov, M. & Granot, D. (1995) Arabidopsis thalania hexokinase cDNA isolated by complementation of yeast cells, Plant. Physiol. (Bethesda) 180, 879-880.
    • (1995) Plant. Physiol. (Bethesda) , vol.180 , pp. 879-880
    • Dai, A.1    Schaffer, A.A.2    Petreikov, M.3    Granot, D.4
  • 10
    • 0023947436 scopus 로고
    • Isolation and expression of the Aspergillus nidulans pyruvate kinase gene
    • De Graaff, L., Van den Broek, H. & Visser, J. (1988) Isolation and expression of the Aspergillus nidulans pyruvate kinase gene, Curr. Genet. 13, 315-321.
    • (1988) Curr. Genet. , vol.13 , pp. 315-321
    • De Graaff, L.1    Van Den Broek, H.2    Visser, J.3
  • 11
    • 7844249262 scopus 로고
    • Yeast hexokinase. II. Molecular mass and dissociation behaviour
    • Derechin, M., Ramel, A. R., Lazarus, N. R. & Barnard, E. A. (1966) Yeast hexokinase. II. Molecular mass and dissociation behaviour, Biochemistry 5, 4017-4026.
    • (1966) Biochemistry , vol.5 , pp. 4017-4026
    • Derechin, M.1    Ramel, A.R.2    Lazarus, N.R.3    Barnard, E.A.4
  • 12
    • 0015498979 scopus 로고
    • Dissociation of yeast hexokinase under the influence of substrates
    • Derechin, M., Rustum, Y. M. & Barnard, E. A. (1972) Dissociation of yeast hexokinase under the influence of substrates, Biochemistry 11, 1793-1797.
    • (1972) Biochemistry , vol.11 , pp. 1793-1797
    • Derechin, M.1    Rustum, Y.M.2    Barnard, E.A.3
  • 13
    • 0015504875 scopus 로고
    • Purification and subunit interactions of yeast hexokinase
    • Easterby, J. S. & Rosemeyer, M. A. (1972) Purification and subunit interactions of yeast hexokinase, Eur. J. Biochem. 28, 241-252.
    • (1972) Eur. J. Biochem. , vol.28 , pp. 241-252
    • Easterby, J.S.1    Rosemeyer, M.A.2
  • 14
    • 0003437299 scopus 로고
    • Distributed by the author, Department of Genetics, University of Washington, Seattle, USA
    • Felsenstein, J. (1993) Phylogeny inference package (Phylip) version 3.5c. Distributed by the author, Department of Genetics, University of Washington, Seattle, USA.
    • (1993) Phylogeny Inference Package (Phylip) Version 3.5c
    • Felsenstein, J.1
  • 15
    • 0021802750 scopus 로고
    • The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression
    • Fröhlich, K. U., Entian, K. D. & Mecke, D. (1985) The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression, Gene (Amst.) 36, 105-111.
    • (1985) Gene (Amst.) , vol.36 , pp. 105-111
    • Fröhlich, K.U.1    Entian, K.D.2    Mecke, D.3
  • 17
    • 0023465935 scopus 로고
    • Transformation of Aspergillus niger using the homologous orotidine-5′-phosphate-decarboxylase gene
    • Goosen, T., Bloemheuvel, G., Gysler, C., De Bie, D. A., Van den Broek, H. W. J. & Swart, K. (1987) Transformation of Aspergillus niger using the homologous orotidine-5′-phosphate-decarboxylase gene, Curr. Genet. 11, 499-503.
    • (1987) Curr. Genet. , vol.11 , pp. 499-503
    • Goosen, T.1    Bloemheuvel, G.2    Gysler, C.3    De Bie, D.A.4    Van Den Broek, H.W.J.5    Swart, K.6
  • 18
    • 0024511710 scopus 로고
    • Synthesis and characterization of a bovine hexokinase I (HK1) cDNA probe by mixed oligonucleotide primed amplification of cDNA using high complexity primer mixtures
    • Griffin, L. D., MacGregor, G. R., Muzny, D. M., Harter, J., Cook, R. G. & McCabe, E. R. (1989) Synthesis and characterization of a bovine hexokinase I (HK1) cDNA probe by mixed oligonucleotide primed amplification of cDNA using high complexity primer mixtures, Biochem. Med. Metab. Biol. 41, 125-131.
    • (1989) Biochem. Med. Metab. Biol. , vol.41 , pp. 125-131
    • Griffin, L.D.1    MacGregor, G.R.2    Muzny, D.M.3    Harter, J.4    Cook, R.G.5    McCabe, E.R.6
  • 19
    • 0025105710 scopus 로고
    • Cloning and expression of a second Aspergillus niger pectin lyase gene (pelA): Indication of a pectin lyase gene family in Aspergillus niger
    • Harmsen, J. A. M., Kusters-van Someren, M. A. & Visser, J. (1990) Cloning and expression of a second Aspergillus niger pectin lyase gene (pelA): indication of a pectin lyase gene family in Aspergillus niger, Curr. Genet. 18, 161-166.
    • (1990) Curr. Genet. , vol.18 , pp. 161-166
    • Harmsen, J.A.M.1    Kusters-van Someren, M.A.2    Visser, J.3
  • 20
    • 0025291214 scopus 로고
    • Screening method for large numbers of dye-adsorbants for enzyme purification
    • Hondmann, D. H. A. & Visser, J. (1990) Screening method for large numbers of dye-adsorbants for enzyme purification, J. Chromatogr. 510, 155-164.
    • (1990) J. Chromatogr. , vol.510 , pp. 155-164
    • Hondmann, D.H.A.1    Visser, J.2
  • 21
    • 0021947210 scopus 로고
    • Glucose repression and hexokinase enzymes in yeast. Isolation and characterization of a modified hexokinase PII isoenzyme
    • Kopetzki, E. & Entian, K. D. (1985) Glucose repression and hexokinase enzymes in yeast. Isolation and characterization of a modified hexokinase PII isoenzyme, Eur, J. Biochem. 146, 657-662.
    • (1985) Eur, J. Biochem. , vol.146 , pp. 657-662
    • Kopetzki, E.1    Entian, K.D.2
  • 22
    • 0022358131 scopus 로고
    • Complete nucleotide sequence of the hexokinase PI gene (HXK1) of Saccharomyces cerevisiae
    • Kopetzki, E., Entian, K. D. & Mecke, D. (1985) Complete nucleotide sequence of the hexokinase PI gene (HXK1) of Saccharomyces cerevisiae, Gene (Abst.) 39, 95-102.
    • (1985) Gene (Abst.) , vol.39 , pp. 95-102
    • Kopetzki, E.1    Entian, K.D.2    Mecke, D.3
  • 23
    • 0026636552 scopus 로고
    • Human islet glucokinase gene: Isolation and sequence analysis of full-length cDNA
    • Koranyi, L. I., Tanizawa, Y., Welling, C. M., Rabin, D. U. & Permutt, M. A. (1992) Human islet glucokinase gene: isolation and sequence analysis of full-length cDNA, Diabetes 41, 807-811.
    • (1992) Diabetes , vol.41 , pp. 807-811
    • Koranyi, L.I.1    Tanizawa, Y.2    Welling, C.M.3    Rabin, D.U.4    Permutt, M.A.5
  • 24
    • 0025910182 scopus 로고
    • Structure of the Aspergillus niger pelA gene and its expression in Apergillus niger and Aspergillus nidulans
    • Kusters-van Someren, M. A., Harmsen, J. A. M., Kester, H. C. M. & Visser, J. (1991) Structure of the Aspergillus niger pelA gene and its expression in Apergillus niger and Aspergillus nidulans, Curr. Genet. 20, 293-299.
    • (1991) Curr. Genet. , vol.20 , pp. 293-299
    • Kusters-van Someren, M.A.1    Harmsen, J.A.M.2    Kester, H.C.M.3    Visser, J.4
  • 25
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 26
    • 0017382789 scopus 로고
    • Physiological role of glucose phosphorylating enzymes in Saccharomyces cerevisiae
    • Lobo, Z. & Maitra, P. K. (1977a) Physiological role of glucose phosphorylating enzymes in Saccharomyces cerevisiae, Arch. Biochem. Biophys. 182, 639-645.
    • (1977) Arch. Biochem. Biophys. , vol.182 , pp. 639-645
    • Lobo, Z.1    Maitra, P.K.2
  • 27
    • 0017650913 scopus 로고
    • Genetics of yeast hexokinase
    • Lobo, Z. & Maitra, P. K. (1977b) Genetics of yeast hexokinase, Genetics 86, 727-744.
    • (1977) Genetics , vol.86 , pp. 727-744
    • Lobo, Z.1    Maitra, P.K.2
  • 28
    • 0024462439 scopus 로고
    • An alternate promoter in the glucokinase gene is active in the pancreatic beta cell
    • Magnuson, M. A. & Shelton, K. D. (1989) An alternate promoter in the glucokinase gene is active in the pancreatic beta cell, J. Biol. Chem. 264, 15936-15942.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15936-15942
    • Magnuson, M.A.1    Shelton, K.D.2
  • 29
    • 0014939505 scopus 로고
    • A glucokinase from Saccharomyces cerevisiae
    • Maitra, P. K. (1970) A glucokinase from Saccharomyces cerevisiae, J. Biol. Chem. 245, 2423-2431.
    • (1970) J. Biol. Chem. , vol.245 , pp. 2423-2431
    • Maitra, P.K.1
  • 30
    • 0021088893 scopus 로고
    • Genetics of yeast glucokinase
    • Maitra, P. K. & Lobo, Z. (1983) Genetics of yeast glucokinase, Genetics 105, 501-515.
    • (1983) Genetics , vol.105 , pp. 501-515
    • Maitra, P.K.1    Lobo, Z.2
  • 31
    • 0023106422 scopus 로고
    • An unusual hexose-ATP-kinase with two catalytic sites and a role in carbon-catabolite repression in the yeast Schwanniomyces occidentalis
    • McCann, A. K., Hilberg, F., Kenworthy, P. & Barnett, J. A. (1987) An unusual hexose-ATP-kinase with two catalytic sites and a role in carbon-catabolite repression in the yeast Schwanniomyces occidentalis, J. Gen. Microbiol. 133, 381-389.
    • (1987) J. Gen. Microbiol. , vol.133 , pp. 381-389
    • McCann, A.K.1    Hilberg, F.2    Kenworthy, P.3    Barnett, J.A.4
  • 32
    • 0024202709 scopus 로고
    • Human hexokinase: Sequences of amino- and carboxyl-terminal halves are homologous
    • Nishi, S., Seino, S. & Bell, G. I. (1988) Human hexokinase: sequences of amino- and carboxyl-terminal halves are homologous, Biochem. Biophys. Res. Commun. 157, 937-943.
    • (1988) Biochem. Biophys. Res. Commun. , vol.157 , pp. 937-943
    • Nishi, S.1    Seino, S.2    Bell, G.I.3
  • 33
    • 0026460334 scopus 로고
    • Molecular analysis of Plasmodium falciparum hexokinase
    • Olafsson, P., Matile, H. & Cesta, U. (1992) Molecular analysis of Plasmodium falciparum hexokinase, Mol. Biochem. Parasitol. 56, 89-102.
    • (1992) Mol. Biochem. Parasitol. , vol.56 , pp. 89-102
    • Olafsson, P.1    Matile, H.2    Cesta, U.3
  • 35
    • 0027280268 scopus 로고
    • The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis
    • Prior, C., Mamessier, P., Fukuhara, H., Chen, X. J. & Wesolowski-Louvel, M. (1993) The hexokinase gene is required for transcriptional regulation of the glucose transporter gene RAG1 in Kluyveromyces lactis, Mol. Cell. Biol. 13, 3882-3889.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3882-3889
    • Prior, C.1    Mamessier, P.2    Fukuhara, H.3    Chen, X.J.4    Wesolowski-Louvel, M.5
  • 36
    • 0001235870 scopus 로고
    • Citric acid
    • (Rehm, H. J. & Reed, G., eds) Verlag Chemie, Weinheim
    • Röhr, M., Kuhicek, C. P. & Kominek, J. (1983) Citric acid, in Biotechnology (Rehm, H. J. & Reed, G., eds) vol. 3. pp. 419-454, Verlag Chemie, Weinheim.
    • (1983) Biotechnology , vol.3 , pp. 419-454
    • Röhr, M.1    Kuhicek, C.P.2    Kominek, J.3
  • 37
    • 0026490710 scopus 로고
    • Industrial acids and other small molecules
    • (Bennet, J. W. & Klich, M. A., eds) Butterworth-Heidemann, Stoneham
    • Röhr, M., Kubicek, C. P. & Kominek, J. (1992) Industrial acids and other small molecules, in Aspergilli. Biology and industrial applications (Bennet, J. W. & Klich, M. A., eds) pp. 91-131, Butterworth-Heidemann, Stoneham.
    • (1992) Aspergilli. Biology and Industrial Applications , pp. 91-131
    • Röhr, M.1    Kubicek, C.P.2    Kominek, J.3
  • 38
    • 0028953820 scopus 로고
    • Molecular and biochemical characterisation of the hexokinase from the starch-utilizing yeast Schwanniomyces occidentalis
    • Rose, M. (1995) Molecular and biochemical characterisation of the hexokinase from the starch-utilizing yeast Schwanniomyces occidentalis, Curr. Genet. 27, 330-338.
    • (1995) Curr. Genet. , vol.27 , pp. 330-338
    • Rose, M.1
  • 39
    • 0342644400 scopus 로고
    • Hexokinase aus Aspergillus oryzae
    • Ruiz-Amil, M. & Sols, A. (1961) Hexokinase aus Aspergillus oryzae, Biochem. Z. 334, 168-174.
    • (1961) Biochem. Z. , vol.334 , pp. 168-174
    • Ruiz-Amil, M.1    Sols, A.2
  • 41
    • 0342526544 scopus 로고
    • Molecular model of human β-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B
    • St Charles, R., Harrison, R. W., Bell, G. I., Pilkis, S. J. & Weber, I. T. (1994) Molecular model of human β-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B, Diabetes 43, 784-791.
    • (1994) Diabetes , vol.43 , pp. 784-791
    • St Charles, R.1    Harrison, R.W.2    Bell, G.I.3    Pilkis, S.J.4    Weber, I.T.5
  • 42
    • 0023655677 scopus 로고
    • Amino acid sequence at the substrate hexose binding site is homologous to that of yeast hexokinase
    • Schirch, D. M. & Wilson, J. E. (1987) Amino acid sequence at the substrate hexose binding site is homologous to that of yeast hexokinase, Arch. Biochem. Biophys. 257, 1-12.
    • (1987) Arch. Biochem. Biophys. , vol.257 , pp. 1-12
    • Schirch, D.M.1    Wilson, J.E.2
  • 43
    • 0007941325 scopus 로고
    • Increased citric acid production by mutants of Aspergillus niger with increased glycolytic capacity
    • Schreferl-Kunar, G., Grotz, M., Röhr, M. & Kubicek, C. P. (1989) Increased citric acid production by mutants of Aspergillus niger with increased glycolytic capacity, FEMS Microbiol. Lett. 59, 297-300.
    • (1989) FEMS Microbiol. Lett. , vol.59 , pp. 297-300
    • Schreferl-Kunar, G.1    Grotz, M.2    Röhr, M.3    Kubicek, C.P.4
  • 44
    • 0024605390 scopus 로고
    • Complete amino acid sequence of rat brain hexokinase, deduced from cloned cDNA, and proposed structure of a mammalian hexokinase
    • Schwab, D. A. & Wilson, J. E. (1989) Complete amino acid sequence of rat brain hexokinase, deduced from cloned cDNA, and proposed structure of a mammalian hexokinase, Proc. Natl Acad. Sci. USA 86, 2563-2567.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 2563-2567
    • Schwab, D.A.1    Wilson, J.E.2
  • 45
    • 0025905408 scopus 로고
    • Complete amino acid sequence of the type III isozyme of rat hexokinase, deduced from the cloned cDNA
    • Schwab, D. A. & Wilson, J. E. (1991) Complete amino acid sequence of the type III isozyme of rat hexokinase, deduced from the cloned cDNA, Arch. Biochem. Biophys. 285, 365-370.
    • (1991) Arch. Biochem. Biophys. , vol.285 , pp. 365-370
    • Schwab, D.A.1    Wilson, J.E.2
  • 46
    • 0016274520 scopus 로고
    • Monomer-dimer equilibria of yeast hexokinase during reacting enzyme sedimentation
    • Shill, P. S., Peters, B. A. & Neet, K. E. (1974) Monomer-dimer equilibria of yeast hexokinase during reacting enzyme sedimentation, Biochemistry 13, 3865-3871.
    • (1974) Biochemistry , vol.13 , pp. 3865-3871
    • Shill, P.S.1    Peters, B.A.2    Neet, K.E.3
  • 47
    • 0028821662 scopus 로고
    • Schistosoma mansoni hexokinase: cDNA cloning and immunogenecity studies
    • Shoemaker, C. B., Reynolds, S., Wei, G. & Harn, D. (1995) Schistosoma mansoni hexokinase: cDNA cloning and immunogenecity studies, Exp. Parasitol. 80, 36-45.
    • (1995) Exp. Parasitol. , vol.80 , pp. 36-45
    • Shoemaker, C.B.1    Reynolds, S.2    Wei, G.3    Harn, D.4
  • 48
    • 0028272233 scopus 로고
    • Characterization and regulatory properties of a single hexokinase from the citric acid accumulating fungus Aspergillus niger
    • Steinböck, F., Choojun, S., Held, I., Röhr, M. & Kubicek, C. P. (1994) Characterization and regulatory properties of a single hexokinase from the citric acid accumulating fungus Aspergillus niger, Biochim. Biophys. Acta. 1200, 215-223.
    • (1994) Biochim. Biophys. Acta , vol.1200 , pp. 215-223
    • Steinböck, F.1    Choojun, S.2    Held, I.3    Röhr, M.4    Kubicek, C.P.5
  • 49
    • 0025773195 scopus 로고
    • Human liver glucokinase gene: Cloning and sequence determination of two alternatively spliced cDNAs
    • Tanizawa, Y., Koranyi, L. I., Welling, C. M. & Permutt, M. A. (1991) Human liver glucokinase gene: cloning and sequence determination of two alternatively spliced cDNAs. Proc. Natl Acad. Sci. USA 88, 7294-7297.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 7294-7297
    • Tanizawa, Y.1    Koranyi, L.I.2    Welling, C.M.3    Permutt, M.A.4
  • 50
    • 0025873080 scopus 로고
    • Complete amino acid sequence of the type II isoenzyme of rat hexokinase, deduced from the cloned cDNA: Comparison with a hexokinase from Novikoff ascites tumor
    • Thelen, A. P. & Wilson, J. E. (1991) Complete amino acid sequence of the type II isoenzyme of rat hexokinase, deduced from the cloned cDNA: comparison with a hexokinase from Novikoff ascites tumor, Arch. Biochem. Biophys. 286, 645-651.
    • (1991) Arch. Biochem. Biophys. , vol.286 , pp. 645-651
    • Thelen, A.P.1    Wilson, J.E.2
  • 51
    • 0028985536 scopus 로고
    • Trehalose synthase: Guard to the gate of glycolysis in yeast?
    • Thevelein, J. M. & Hohmann, S. (1995) Trehalose synthase: guard to the gate of glycolysis in yeast? Trends Biochem. Sci. 20, 3-10.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 3-10
    • Thevelein, J.M.1    Hohmann, S.2
  • 52
    • 0028765255 scopus 로고
    • Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. I. Model definition and stability of the steady state
    • Torres, N. V. (1994a) Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. I. Model definition and stability of the steady state, Biotechnol. Bioeng. 44, 104-111.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 104-111
    • Torres, N.V.1
  • 53
    • 0028765252 scopus 로고
    • Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. II. Sensitivity analysis
    • Torres, N. V. (1994b) Modeling approach to control of carbohydrate metabolism during citric acid accumulation by Aspergillus niger. II. Sensitivity analysis, Biotechnol. Bioeng. 44, 112-118.
    • (1994) Biotechnol. Bioeng. , vol.44 , pp. 112-118
    • Torres, N.V.1
  • 54
    • 0002858205 scopus 로고
    • Gene organisation in filamenrous fungi
    • (Kinghorn, J. R. & Turner. G., eds) Blackie Academic and Professional, Glasgow
    • Unkles, S. E. (1992) Gene organisation in filamenrous fungi, in Applied molecular genetics of filamentous fungi (Kinghorn, J. R. & Turner. G., eds) pp. 28-53, Blackie Academic and Professional, Glasgow.
    • (1992) Applied Molecular Genetics of Filamentous Fungi , pp. 28-53
    • Unkles, S.E.1
  • 56
    • 0012116614 scopus 로고
    • A hexokinase associated with catabolite repression in Pachysolen tannophilus
    • Wedlock, D. N. & Thornton, R. J. (1989) A hexokinase associated with catabolite repression in Pachysolen tannophilus, J. Gen. Microbiol. 135, 2013-2018.
    • (1989) J. Gen. Microbiol. , vol.135 , pp. 2013-2018
    • Wedlock, D.N.1    Thornton, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.