Priapism: Etiology and management

Academic Emergency Medicine

Volumn 3, Issue 8, 1996, Pages 810-816

  Mulhall, John P ^a,b   Honig, Stanton C ^a,c  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c YALE NEW HAVEN HOSPITAL   (United States)

Author keywords

diagnosis; management; priapism; review; sickle cell disease; urology

Indexed keywords

ADRENALIN; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; ANTICOAGULANT AGENT; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUTYROPHENONE DERIVATIVE; GONADORELIN DERIVATIVE; HYDRALAZINE; HYDROXYZINE; HYPNOTIC SEDATIVE AGENT; LIDOCAINE; METARAMINOL; METOCLOPRAMIDE; NIFEDIPINE; NORADRENALIN; OMEPRAZOLE; PAPAVERINE; PHENOTHIAZINE DERIVATIVE; PHENOXYBENZAMINE; PHENTOLAMINE; PHENYLEPHRINE; PRAZOSIN; PROSTAGLANDIN E1; PSEUDOEPHEDRINE; PSYCHOTROPIC AGENT; SEROTONIN UPTAKE INHIBITOR; TERBUTALINE; TRAZODONE; UNINDEXED DRUG;

BRADYCARDIA; CORPUS CAVERNOSUM; DRUG INDUCED DISEASE; EMERGENCY TREATMENT; HEADACHE; HUMAN; HYPERTENSION; IDIOPATHIC DISEASE; IMPOTENCE; LOCAL ANESTHESIA; MALE; PENIS INJURY; PRIAPISM; PRIORITY JOURNAL; REVIEW; SICKLE CELL ANEMIA;

EID: 0029765797     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.1996.tb03520.x     Document Type: Review

References (70)

1. Martin EL, Bennett AH. latrogenic causes of impotence. In: Bennett AH (ed). Impotence: Diagnosis and Management of Erectile Dysfunction. Philadelphia: W. B. Saunders, 1994, pp 135-144.
2. Papadopoulos I, Kelami A. Priapus and priapism: from mythology to medicine. Urology. 1988; 32:385-7.
3. Winter CC, McDowell G. Experience with 105 patients with priapism: update review of all aspects. J Urol. 1988; 140: 980-2.
4. Callaway T. Unusual case of priapism. London Med Repository. 1824; 1:286-7.
5. Melman A, Christ GJ, Hirsch MS. Anatomy and physiology of the penis. In: Bennett AH (ed). Impotence. Diagnosis and Management of Erectile Dysfunction. Philadelphia: W. B. Saunders, 1994, pp 18-30.
6. Kim, N, Azadzoi KM, Goldstein I, Saenz de Tejada I. A nitric oxide-like factor mediates non-adrenergic non-cholinergic neurogenic relaxation of penile corpus cavernosum smooth muscle. J Clin Invest. 1991; 88:112-6.
7. Hauri D, Spycher M, Bruhlmann W. Erection and priapism. a new physiopathological concept. Urol Int. 1983; 38: 138-41.
8. Bastuba MD, Saenz de Tejada I, Dinclenc CZ, Sarazen A, Krane RJ, Goldstein I. Arterial priapism. diagnosis, treatment and long-term follow-up. J Urol. 1994; 151:1231-7.
9. Banos JE, Bosch F, Farre M. Drug-induced priapism. etiology, incidence and treatment. Med Toxicol. 1989; 4:46-7.
10. Junemann KP, Alken P. Pharmacotherapy of erectile dysfunction, a review. Int J Impot Res. 1989; 1:71-5.
11. Stackl W, Mee SL. Priapism. In: Krane RJ, Siroky MB, Fitzpatrick JM (eds). Clinical Urology. Philadelphia: J. B. Lippincott, 1994, pp 1245-58.
12. Rubin SO. Priapism as a probable sequel to medication. Scand J Urol Nephrol. 1968; 2:81-2.
13. Bullock N. Prazosin-induced priapism. Br J Urol. 1988; 62:487-8.
14. Law MR, Copland RFP, Armistead JG, Gabriel R. Labetalol and priapism. Br Med J. 1980; 280:115-6.
15. Rayner HC, May S, Walls J. Penile erection due to nifedipine. Br Med J. 1988; 296:137-8.
16. Dorman BW, Schmidt JD. Association of priapism in phenothiazine therapy. J Urol. 1976; 116:51-3.
17. Abber JC, Lue TF, Luo JA, Junemann KP, Tanagho EA. Priapism induced by chlorpromazine and trazadone. J Uol. 1987; 137:1039-41.
18. Chan J, Alldredge BK, Baskin LS. Perphenazine-induced priapism. Drug Intell Clin Pharm. 1990; 24:246-8.
19. Velek M, Stanford DK, Marco L. Priapism associated with concurrent use of thioridazine and metoclopramide. Am J Psychiatry. 1987; 144:827-9.
20. Greenberg WM, Lee KK. Priapism treated with benztropine. Am J Psychiatry. 1987; 144:384-5.
21. Seftel A, Saenz de Tejada I, Szetala B, Cole J, Goldstein I: Clozapine-associated priapism: a case report. J Urol. 1992; 147:146-7.
22. Vale JA, Kirby RS, Lees W. Papaverine, benzodiazepines and prolonged erections. Lancet. 1991; 337:1552-3.
23. Ereshefsky L, Watanabe MD, TranJohnson TK. Clozapine: an atypical antipsychotic agent. Clin Pharmacol. 1989; 8:691-3.
24. Lance R, Albo M, Costabile RA, Steers W. Oral trazadone as empirical therapy for erectile dysfunction: a retrospective review. Urology. 1995; 46:117-20.
25. Saenz de Tejada I, Ware JC, Blanco R. et al. Pathophysiology of prolonged penile erection associated with trazadone use. J Urol. 1991; 145:60-2.
26. Steers WD, Albo M, Asselt EV. Effects of serotonin agonists on micturition and sexual function in the rat. Drug Dev Res. 1992; 27:361-75.
27. Ashwin JG. The effect of drugs on experimental thrombogenesis in anticoagulants and fibrinolysins. In: McMillan MJ (ed). Anticoagulants and Fibrinolysins. Toronto: Macmillan, 1983, 117-28.
28. Elkstrom B, Olsson AM. Priapism in patients treated with total parenteral nutrition. Br J Urol. 1987; 59:170-2.
29. Grace DA, Winter CC. Priapism: an appraisal of management of twenty-three patients. J Urol. 1968; 99:301-4.
30. Fiorelli RL, Manfrey SJ, Belkhoff LH, Finlestein LH. Priapism associated with intranasal cocaine use. J Urol. 1990; 143: 581-2.
31. Jiva T, Anwer S. Priapism associated with chronic cocaine use. Arch Intern Med. 1994; 154:1770-2.
32. Forsberg L, Mattiasson A, Olsson AM. Priapism: conservative treatment versus surgical procedures. BrJ Urol. 1981; 53: 374-8.
33. Lakoski JM, Cunningham KA. The interaction of cocaine with central serotonergic neuronal systems, cellular electrophysiologic approaches. Natl Inst Drug Abuse Res Monogr Ser. 1988; 88:78-81.
34. Amris CJ, Brockner J, Larson V. Changes in the coagulability of blood during infusion of intralipid. Acta Chir Scand (Suppl). 1964; 325:70-4.
35. Hamre MR, Harmin EP, Kirkpatrick DV, Stern MJ, Humbert JR. Priapism as a complication of sickle cell disease. J Urol. 1991; 145:1-6.
36. Gupta A, Bambrey P, Varma S, Vaidyanathan S, Deodhar SD. Priapism in chronic myeloid leukemia: combined medical and surgical treatment. Ind J Cancer. 1987; 24:176-8.
37. Bedbrook G. Care and management of the spinal cord injured patient. New York: Springer-Verlag, 1981.
38. Adogu AA. Stuttering priapism in sickle cell disease. Br J Urol. 1991; 67:105-6.
39. Pohl J, Pott B, Kleinhaus G. Priapism: a three-phase concept of management according to etiology and prognosis. Br J Urol. 1986; 58:113-6.
40. Lue TF. McAninch JW. Priapism. In: Tanagho EA, Lue TF, McClure RD, (eds). Comtemporary Management of Impotence and Infertility. Baltimore: Williams and Wilkins, 1988, p 201.
41. Lee M, Cannon B, Sharifi R. Chart for preparation of dilutions of alpa-adrenergic agonists for use in the treatment of priapism. J Urol. 1995; 153:1182-3.
42. Lue TF. Physiology of erection and pathophysiology of impotence. In: Walsh PC, Retik AB, Stamey TA, Vaughan ED (eds). Campbell's Urology. 6th ed. Philadelphia: W. B. Saunders, 1992, p 709.
43. Bos SD, Buys GA. Treatment of priapism with ethyl chloride spray after failed intracavernous injection of adrenaline. Br J Urol. 1994; 74:677-8.
44. Mejean A, Marc B, Rigot JM, Mazeman E. Use of methylene blue and selective embolization of the pudendal artery for high-flow priapism refractory to medical and surgical treatments. J Urol. 1993; 149:1149-51.
45. Baruchel S, Rees J, Bernstein ML, Goodyer P. Relief of sickle cell priapism by hydralazine. Report of a case. Am J Pediatr Hematol Oncol. 1993; 15:115-6.
46. Stothers L, Ritchie B. Priapism in the newborn. Can J Surg. 1992; 35:325-6.
47. Steers WD, Selby JB. Use of methylene blue and selective embolization of the pudendal artery for high-flow priapism refractory to medical and surgical treatments. J Urol. 1991; 146:1361-4.
48. Levine FJ, Saenz de Tejada I, Payton TR, Goldstein I. Recurrent prolonged erections and priapism as a sequela of priapism: pathophysiology and management. J Urol. 1991; 145:764-8.
49. Hakim LS, Goldstein I. Evolving concepts in the management of arterial high-flow priapism. J Urol. 1996; 155:541-50.
50. Shanta TR, Finnerty DR, Rodriguez AP. Treatment of persistent erection and priapism using terbutaline. J Urol. 1989; 141:1427-9.
51. Govier FE, Jonsson E, Kramer-Levien D. Oral terbutaline for treatment of priapism. J Urol. 1994; 151:878-9.
52. Soni BM, Vaidyanathan S, Krishnan KR. Management of pharmacologically-induced prolonged penile erection with oral terbutaline in traumatic paraplegics. Paraplegia. 1994; 32:670-4.
53. Levine LA, Guss SP. Gonadotropin-releasing hormone analogues in the treatment of sickle cell anemia-associated priapism. J Urol. 1993; 150:455-7.
54. Fernando IN, Tobias JS. Priapism in a patient on tamoxifen. Lancet. 1989; i: 436-8.
55. Ruch W, Jenny P. Priapism following testosterone administration for delayed puberty. Am J Med. 1989; 86:256-8.
56. Dutertre JP, Soutif D, Jonville AP, Cadenne M, Valat JP, Autret E. Sexual disturbances during omeprazole therapy [letter]. Lancet. 1991; 338:1022.
57. Tavundayil JX, Hambalek R, Ng Ying Kin N, Krishnan B, Lal S. Prolonged penile erections induced by hydroxyzine: possible mechanism of action. Neuropsychobiology. 1994; 30:4-6.
58. Gumruk F, Hicsonmez G, Ozsoylu S, Gurgey A, Tuncer AM. High dose methylprednisolone for the treatment of priapism in childhood leukemia. Pediatr Hematol Oncol. 1991; 8:367-8.
59. Agrawal DK, Jha S, Verma A, Tripathi AK, Singh BN. Priapism, complicating chronic myeloid leukemia: a case report. Ind J Cancer. 1991; 28:51-2.
60. Flanagan NG, Jain A, Ridway JC. Priapism in myeloma. Clin Lab Hematol. 1987; 9:209-12.
61. Fowler JE, Koshy M, Strub M, Chinn SK. Priapism associated with sickle cell hemoglobinopathies: prevalence, natural history and sequelae. J Urol. 1991; 145: 65-8.
62. Dore F, Bonfigli S, Pardini S, Pirozzi F, Longinotti M. Priapism in thalassemia intermedia. Hematplogia. 1991; 76:523-5.
63. Garcia-Consuegra J, Padron M, Jaureguizar E, Carrascosa C, Ramos J. Priapism and Fabry's disease. Eur J Pediatr. 1990; 149:500-3.
64. Parillo SJ, Manfrey S. Idiopathic priapism treated with inhalation of amyl nitrite. Ann Emerg Med. 1983; 12:226-9.
65. Dogra PN, Wadwa SN, Mehta VK. Vivax malaria causing priapism. J Assoc Phys India. 1991; 39:571-2.
66. Stiles AD. Priapism following a black widow spider bite. Clin Pediatr. 1982; 21:174-5.
67. Hidalgo-Ovejero AM, Garcia-Mata S, Sauras-Herranz MA, Maravi-Petri E, Martinez-Grande M. Intermittent priapism in spinal stenosis. Acta Orthop Belg. 1991; 57:192-4.
68. Baba H, Furasawa N, Tanaka Y, Imura S, Tomita K. Intermittent priapism associated with lumbar spinal stenosis. Int Orthop. 1994; 18:150-3.
69. Atala A, Amin M, Harty JI, Liu YK, Keeling MM. Priapism associated with asplenic state. Urology. 1992; 4:40-3.
70. +-ATPaSe in the regulation of human corpus cavernosum smooth muscle contractility by nitric oxide. Br J Pharmacol. 1995; 116:2201-6.