The reduction of alcohol consumption with novel pharmacological intervention

European Psychiatry

Volumn 11, Issue 5, 1996, Pages 217-226

  Sperling, W ^a   Lesch, O M ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

acamprosat; alcoholism; craving; lithium; opioids; serotonin

Indexed keywords

ACAMPROSATE; AMITRIPTYLINE; ATENOLOL; BUSPIRONE; CITALOPRAM; ENALAPRIL; FLUOXETINE; FLUPENTIXOL; GRANISETRON; HALOPERIDOL; IPSAPIRONE; LITHIUM; MIANSERIN; MIDAZOLAM; MORPHINE; NALTREXONE; ONDANSETRON; OPIATE; OPIATE ANTAGONIST; SEROTONIN; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SERTRALINE;

ALCOHOL CONSUMPTION; HUMAN; MEDICAL LITERATURE; NEUROTRANSMISSION; PRIORITY JOURNAL; REVIEW;

EID: 0029765551     PISSN: 09249338     EISSN: None     Source Type: Journal    
DOI: 10.1016/0924-9338(96)82327-3     Document Type: Review

References (55)

1. Ades J, Barrias JA, Besson J, Borg S, Lesch OM. Guidelines on evaluation of treatment of alcohol dependence. J Alcohol Related Addict 1994;xxx(Suppl)
2. Amit Z, Smith BR. Neurotransmitter systems in ethanol intake. Satellite Symposium to the 5th ISBRA conference - Novel pharmacological interventions for alcoholism - Addiction Research Foundation, Toronto, Canada, 1990
3. Bilsky EJ, Delconte J. Mianserin, a serotonergic antagonist, and intake of an alcoholism beverage. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
4. Borg V. Bromocriptine in the prevention of alcohol abuse. Acta Psychiatr Scand 1983;68(2):100-10
5. Cloninger CR, Sigvardsson S, Gilligan SB. Genetic heterogeneity and the classification of alcohol. Adv Alcohol Subst Abuse 1988;7:3-16
6. Compagnon P. Serotonin in animal models of alcoholism. Alcohol and Alcoholism 1993;2:215-9
7. Diagnostische Kriterien and Differentialdiagnosen des Diagnostischen und statistischen Manuals psychischer Störungen DSM-III-R. Weinheim, Basel: Beltz, 1989
8. De Vry J. 5-HT-1A receptors in anxiety. In: Brilley M et al, eds. New Concepts in Anxiety. London: Mac Millon, 1991;94-129
9. Dillon KA. Autographic analysis of serotonin 5-HT-1A receptor binding in the human brain postmortem: Effects of age and alcohol. Brain Res 1991;554:56-64
10. Dorus W, Ostrow DG, Anton R, Cushman P, Collins JF, Schaefer M. Lithium treatment of depressed and nondepressed alcoholics (comments). JAMA 1989;262:1680-1
11. Engel JA, Fahlke C, Hard E, Svensson L. Serotonergic involvement in ethanol intake. Satellite Symposium to the 5th ISBRA conference - Novel pharmacological interventions for alcoholism - Addiction Research Foundation, Toronto, Canada, 1990
12. Fawcett J, Clark DC. Evaluation of lithium therapy for alcoholism. J Clin Psychiatry 1984;45:494-9
13. Fawcett MD, Clark DC. A double-blind, placebo-controlled trial of lithium carbonate therapy for alcoholism. Arch Gen Psychiatry 1987;44:248-56
14. Fröhlich JC, Zweifel M, Kurtz D. Opioid antagonists selectively suppress ethanol intake. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
15. Gallimberti L, Ferri M, Ferrara SD, Fadda F, Gessa GI. Gamma-hydroxybutyric acid in the treatment of alcohol dependence: A double-blind study. Alcohol Clin Exper Res 1992;16 (4):673-6
16. Gorrelick DA, Paredes A. Effects of fluoxetine and alcohol consumption in male alcoholics. Alcoholism Clin Exper Res 1992;16:261-5
17. Gottlieb LD, Horwitz RI, Kraus ML. Randomized controlled trial in alcohol relapse prevention, role of atenolol, alcohool craving and treatment adrherence. J Subst Abuse Treat 1994;11:253-8
18. Grupp LA. Angiotensin converting enzyme inhibitors reduce alcohol consumption in rats: Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
19. Higgins GA, Sellers EM. Strategies for the identification of novel serotonergic treatments to selectively reduce ethanol consumption. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
20. Ho AD, Tsai CS. Effects of lithium on alcohol preference and withdrawal. Ann NY Acad Sci 1976;273:371-7
21. Hubbel CL, Chrisbacher GA, Bilsky EJ, Reid LD. Angiotensin converting enzyme inhibitors and intake of an alcoholic beverage. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
22. Judd LL, Huey LY. Lithium antagonizes ethanol intoxication in alcoholics. Am J Psychiatry 1984;141:1517-21
23. Kranzler H. Fluvoxamine is poorly tolerated by alcoholics. Plenary lecture and panel discussion in: Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
24. Kranzler HR, Burleson JA, De Boca FK. Buspirone treatment of anxious alcoholics. A placebo-controlled trial. Arch Gen Psychiatry 1994;51:720-31
25. Kornet M. Behavioural and neuropharmacological aspects of experimental alcohol addiction in rhesus monkeys. Rijswijk TNO 1991
26. Lejoyeux M, Ades J. Evaluation of lithium treatment in alcoholism. Alcohol Alcoholism 1993;28:273-9
27. Lesch OM, Walter H, Bonte W, Grünberger J, Musalek M, Sprung R. Etiology of subgroups in chronic alcoholism and different mechanisms in transmitter systems. In: Norman Palmer T, ed. Alcoholism: a Molecular Perspective. Nato Asi Series A: Life sciences Vol 206. New York: Plenum Press, 1993;145-60
28. Lesch OM, Poldrugo F. The diagnosis of alcoholism: New perspectives in classification. Alcologia 1994;6:11-5
29. Linnoila M, George DT, Wozniak K. Serotonin and alcohol. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
30. Littrell J. Understanding and Treating Alcoholism, Vol 2: Biological, Psychological and Social Aspects of Alcohol Consumption and Abuse. New Jersey, 1991
31. Malcom R. A placebo-controlled trial of buspirone in anxious inpatient alcoholics. Alcohol Clin Exp Res 1992;16: 1007-13
32. Malley SO, Jaffe A, Chang G, Witte G. Naltrexone treatment of alcohol dependence. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
33. McBride WJ. Serotonin in animal models of alcoholism. Alcohol Alcoholism 1990;2:215-9
34. Merry J, Reynolds CM. Prophylactic treatment of alcoholism by lithium carbonate. Lancet 1976;2:481-2
35. Meyer R. Preclinical and clinical methods for testing drugs to decrease alcohol consumption. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
36. Modell JG, Moutz JM, Glaser FB, Lee JY. Effect of haloperidol on measures of craving and impaired control in alcoholic subjects. Alcohol Clinical Exp Res 1993;17 (2):234-40
37. Naranjo CA, Kadlec KE, Ellers EM. Evaluation of the effects of serotonin uptake inhibitors in alcoholics: a review. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
38. Naranjo CA, Sellers EM, Kadlec K, Sanhueza P, Grupp L. Enalapril does not decrease alcohol intake in normotensive alcoholics. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
39. Naranjo CA, Brenner KE. Effects of citalopram and a brief psychosocial intervention on alcohol intake, dependence and problems. Addiction 1995;90:87-94
40. Nichols ML, Bilsky ED, Hubbel CL. Peripheral administration of TIQ's and intake of an alcohol beverage. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
41. Nichols ML, Hubbel CL, Reid LD. Stereoselectivity of opioids effects on intake of an alcoholic beverage. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
42. Olbrich R, Watzl H, Volter M, Siedow H. Lithium in der Behandlung chronischer Alkoholkranker mit zerebralen Schädigungen - eine kontrollierte Studie. Nervenartz 1991; 62:182-6
43. Opitz K. The effect of clonidine and related substances on voluntary ethanol consumption in rats. Drug Alcohol Depend 1990;25:43-8
44. Pelc I, Lebon O, Verbank P, Lehert PH, Opsomer L. Calcium -acetylhomotaurinate for maintaining abstinence in weaned alcoholic patients. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
45. Reid LR, Wong D. 5-Hydroxytryptamine-1A receptor in brain areas of alcohol preferring and non-preferring rats. Fased J 1991;5:865
46. Rommelspacher H, Schmidt LG, May T. Plasma norharman, carboline levels elevated in chronic alcoholics. Clin Exp Res 1991;15:553
47. Sano H. Circadian variations in plasma 5-HTAA level during and after withdrawal. Acta Psychiat Scand 1993;87:291-6
48. Sinclair JD. Preclinical and clinical methods for testing drugs to decrease alcohol consumption. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990
49. Schreiber R, De Vry J. Ipsapirone and 8-OH-DPAT reduce ethanol preference in rats: involvement of presynaptic 5-HT-1A receptors. Psychopharmacology 1993;112:100-10
50. Swift RM, Whelihan W, Kutznesov O. Naltrexone induced alterations in human ethanol intoxication. Am J Psychiatry 1994;151:1463-7
51. Tollefson GD. Serotonin and alcoholism: Interrelationships. Psychopathology 1989;22:37-48
52. Volpicelli JR, Altermann AI, Hayashida M, O'Brien CP. Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry 1992;49 (11):876-80
53. Volpicelli JR, Watson NT, King AC. Effect of naltrexone on alcohol "high" in alcoholics. Am J Psychiatry 1995;152: 613-5
54. Wong DT. Serotonergic and adrenergic receptors in alcohol preferring and non-preferring rats. J Neural Transm 1988; 71:207-18
55. Zeise ML, Kasparow M, Capogna M, Zieglgänsberger W. Calciumdiacetylhomotaurinate decreases the action of excitatory amino acids in the rat neocortex in vitro. Satellite Symposium to the 5th ISBRA Conference - Novel pharmacological interventions for alcoholism. Addiction Research Foundation, Toronto, Canada, 1990