DNA base damage induced by ionizing radiation recognized by Escherichia coli UvrABC nuclease but not Nth or Fpg proteins

Molecular Carcinogenesis

Volumn 16, Issue 4, 1996, Pages 188-196

  Roldán Arjona, Teresa ^a   Sedgwick, Barbara ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

DNA damage; DNA repair; Ionizing radiation; Oxygen radicals

Indexed keywords

NUCLEASE; OXYGEN RADICAL;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ESCHERICHIA COLI; IONIZING RADIATION; PRIORITY JOURNAL;

BACTERIAL PROTEINS; CYTOSINE; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA; DNA DAMAGE; DNA REPAIR; DNA-DIRECTED DNA POLYMERASE; DNA-FORMAMIDOPYRIMIDINE GLYCOSYLASE; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GAMMA RAYS; GUANINE; N-GLYCOSYL HYDROLASES; OXIDATION-REDUCTION;

EID: 0029764880     PISSN: 08991987     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2744(199608)16:4<188::AID-MC2>3.0.CO;2-C     Document Type: Article

References (58)

1. Halliwell B, Aruoma OI. DNA damage by oxygen-derived species. Its mechanism and measurement in mammalian systems. FEBS Lett 281:9-19, 1991.
2. Ames BN, Shigenaga MK. Oxidants are a major contributor to cancer and aging. In: Halliwell B, Aruoma OI (eds), DNA and Free Radicals. Ellis Norwood Ltd, London, 1993, pp. 1-15.
3. von Sonntag C. The Chemical Basis of Radiation Biology. Taylor and Francis Ltd, London, 1987.
4. Dizdaroglu M. Oxidative damage to DNA in mammalian chromatin. Mutat Res 275:331-342, 1992.
5. Cadet J, Weinfeld M. Detecting DNA damage. Anal Chem 65:675-682, 1993.
6. Demple B, Harrison L. Repair of oxidative damage to DNA: Enzymology and biology. Annu Rev Biochem 63:915-948, 1994.
7. Lindahl T. Instability and decay of the primary structure of DNA. Nature 362:709-715, 1993.
8. Breimer LH. Repair of DNA damage induced by reactive oxygen species. Free Radic Res Comm 14:159-171, 1991.
9. Wallace SS. DNA damages processed by base excision repair: Biological consequences. Int J Radiat Biol 66:579-589, 1994.
10. Boiteux S. Properties and biological functions of the NTH and FPG proteins of Escherichia coli: Two DNA glycosylases that repair oxidative damage in DNA. J Photochem Photobiol B 19:87-96, 1993.
11. Hatahet Z, Kow YW, Purmal AA, Cunningham RP, Wallace SS. New substrates for old enzymes. 5-Hydroxy-2′-deoxycytidine and 5-hydroxy-2′-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2′-deoxyuridine is a substrate for uracil DNA N-glycosylase. J Biol Chem 269:18814-18820, 1994.
12. Demple B, Linn S. DNA N-glycosylases and UV repair. Nature 287:203-208, 1980.
13. Dizdaroglu M, Laval J, Boiteux S. Substrate specificity of the Escherichia coli endonuclease III: Excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals. Biochemistry 32:12105-12111, 1993.
14. Breimer LH, Lindahl T. DNA glycosylase activities for thymine residues damaged by ring saturation, fragmentation, or ring contraction are functions of endonuclease III in Escherichia coli. J Biol Chem 259:5543-5548, 1984.
15. Breimer LH, Lindahl T. Thymine lesions produced by ionizing radiation in double-stranded DNA. Biochemistry 24:4018-4022, 1985.
16. Melamede RJ, Hatahet Z, Kow YW, Ide H, Wallace SS. Isolation and characterization of endonuclease VIII from Escherichia coli. Biochemistry 33:1255-1264, 1994.
17. Chetsanga CJ, Lindahl T. Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli. Nucleic Acids Res 6:3673-3684, 1979.
18. Michaels ML, Tchou J, Grollman AP, Miller JH. A repair system for 8-oxo-7,8-dihydrodeoxyguanine. Biochemistry 31:10964-10968, 1992.
19. Boiteux S, Gajewski E, Lavai J, Dizdaroglu M. Substrate specificity of the Escherichia coli Fpg protein (formamidopyrimidine-DNA glycosylase): Excision of purine lesions in DNA produced by ionizing radiation or photosensitization. Biochemistry 31:106-110, 1992.
20. Boiteux S, O'Connor TR, Lederer F, Gouyette A, Laval J. Homogeneous Escherichia coli FPG protein. A DNA glycosylase which excises imidazole ring-opened purines and nicks DNA at apurinic/ apyrimidinic sites. J Biol Chem 265:3916-3922, 1990.
21. Häring M, Rüdiger H, Demple B, Boiteux S, Epe B. Recognition of oxidized abasic sites by repair endonucleases. Nucleic Acids Res 22:2010-2015, 1994.
22. Lin JJ, Sancar A. A new mechanism for repairing oxidative damage to DNA: (A)BC excinuclease removes AP sites and thymine glycolsfrom DNA. Biochemistry 28:7979-7984, 1989.
23. Snowden A, Kow YW, van Houten B. Damage repertoire of the Escherichia coli UvrABC nuclease complex includes abasic sites, base-damage analogues, and lesions containing adjacent 5′ or 3′ nicks. Biochemistry 29:7251-7259, 1990.
24. Satoh MS, Jones CJ, Wood RD, Lindahl T. DNA excision-repair defect of xeroderma pigmentosum prevents removal of a class of oxygen free radical-induced base lesions. Proc Natl Acad Sci USA 90:6335-6339, 1993.
25. Asahara H, Wistort PM, Bank JF, Bakerian RH, Cunningham RP. Purification and characterization of Escherichia coli endonuclease III from the cloned nth gene. Biochemistry 28:4444-4449, 1989.
26. Wood RD, Biggerstaff M, Shivji MKK. Detection and measurement of nucleotide excision repair synthesis by mammalian cell extracts in vitro. Methods: A companion to methods in enzymology 7:163-175, 1995.
27. Sears LE, Moran LS, Kissinger C, et al. CircumVent thermal cycle sequencing and alternative manual and automated DNA sequencing protocols using the highly thermostable VentR (exo-) DNA polymerase. Biotechniques 13:626-633, 1992.
28. Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 74:5463-5467, 1977.
29. Fuciarelli AF, Wegher BJ, Blakely WF, Dizdaroglu M. Yields of radiation-induced base products in DNA: Effects of DNA conformation and gassing conditions Int J Radiat Biol 58:397-415, 1990.
30. Gajewski E, Rao G, Nackerdien Z, Dizdaroglu M. Modification of DNA bases in mammalian chromatin by radiation-generated free radicals. Biochemistry 29:7876-7882, 1990.
31. Sancar A, Sancar GB. DNA repair enzymes. Annu Rev Biochem 57:29-67, 1988.
32. Ide H, Kow YW, Wallace SS. Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro. Nucleic Acids Res 13:8035-8052, 1985.
33. Strauss BS, Wang J. Role of DNA polymerase 3′→5′ exonuclease activity in the bypass of aminofluorene lesions in DNA. Carcinogenesis 11:2103-2109, 1990.
34. Kasai H, Iida A, Yamaizumi Z, Nishimura S, Tanooka H. 5-Formyldeoxyuridine: A new type of DNA damage induced by ionizing radiation and its mutagenicity to Salmonella strain TA102. Mutat Res 243:249-253, 1990.
35. Tchou J, Bodepudi V, Shibutani S, et al. Substrate specificity of Fpg protein. Recognition and cleavage of oxidatively damaged DNA. J Biol Chem 269:15318-15324, 1994.
36. Kamiya H, Miura H, Murata-Kamiya N, et al. 8-Hydroxyadenine (7,8-dihydro-8-oxoadenine) induces misincorporation in vitro DNA synthesis and mutations in NIH 3T3 cells. Nucleic Acids Res 23:2893-2899, 1995.
37. Kamiya H, Ueda T, Ohgi T, Matsukage A, Kasai H. Misincorporation of dAMP opposite 2-hydroxyadenine, an oxidative form of adenine. Nucleic Acids Res 23:761-766, 1995.
38. Bjelland S, Birkeland NK, Benneche T, Volden G, Seeberg E. DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the AlkA enzyme in Escherichia coli. J Biol Chem 269:30489-30495, 1994.
39. Hatahet Z, Purmal AA, Wallace SS. A novel method for site specific introduction of single model oxidative DNA lesions into oligodeoxyribonucleotides. Nucleic Acids Res 21:1563-1568, 1993.
40. Zastawny TH, Doetsch PW, Dizdaroglu M. A novel activity of E. coli uracil DNA N-glycosylase excision of isodialuric acid (5,6-dihydroxyuracil), a major product of oxidative DNA damage, from DNA. FEBS Lett 364:255-258, 1995.
41. Dizdaroglu M, Karakaya A, Jaruga P, Slupphaug G, Krokan HE. Novel activities of human uracil DNA N-glycosylase for cytosine-derived products of oxidative DNA damage. Nucleic Acids Res 24:418-422, 1996.
42. Dizdaroglu M, Simic MG. Radiation-induced crosslinking of cytosine. Radiat Res 100:41-46, 1984.
43. 32P-postlabelling of DNA adducts induced by a Fenton-type oxygen radical-generating system. Carcinogenesis 13:1127-1135, 1992.
44. Keck K. Bildung von cyclonucleotiden bei bestrahlung wassriger losungen von purinnucleotiden. Z Naturforsch [C] 23b:1034-1043, 1968.
45. Fuciarelli AF, Miller GG, Raleigh JA. An immunochemical probe for 8,5′-cycloadenosine-5′-monophosphate and its deoxy analog in irradiated nucleic acids. Radiat Res 104:272-283, 1985.
46. Dizdaroglu M. Free-radical-induced formation of an 8,5′-cyclo-2′-deoxyguanosine moiety in deoxyribonucleic acid. Biochem J 238:247-254, 1986.
47. Dizdaroglu M, Dirksen ML, Jiang HX, Robbins JH. Ionizing-radiation-induced damage in the DNA of cultured human cells. Identification of 8,5-cyclo-2-deoxyguanosine. Biochem J 241:929-932, 1987.
48. Dirksen ML, Blakely WF, Holwitt E, Dizdaroglu M. Effect of DNA conformation on the hydroxyl radical-induced formation of 8,5′-cyclopurine 2′-deoxyribonucleoside residues in DNA. Int J Radiat Biol 54:195-204, 1988.
49. Lafleur MV, Woldhuis J, Loman H. Alkali-labile sites in biologically active DNA: Comparison of radiation induced potential breaks and apurinic sites. Int J Radiat Biol 39:113-118, 1981.
50. Chen H, Shaw BR. bisulfite induces tandem double CC→TT mutations in double-stranded DNA. 2. Kinetics of cytosine deamination. Biochemistry 33:4121-4129, 1994.
51. Box HC, Freund HG, Budzinski EE, Wallace JC, Maccubbin AE. Free radical-induced double base lesions. Radiat Res 141:91-94, 1995.
52. Reid TM, Loeb LA. Mutagenic specificity of oxygen radicals produced by human leukemia cells. Cancer Res 52:1082-1086, 1992.
53. Reid TM, Loeb LA. Effect of DNA-repair enzymes on mutagenesis by oxygen free radicals. Mutat REs 289:181-186, 1993.
54. Reid TM, Loeb LA. Tandem double CC→TT mutations are produced by reactive oxygen species. Proc Natl Acad Sci USA 90:3904-3907, 1993.
55. Tkeshelashvili LK, Reid TM, McBride TJ, Loeb LA. Nickel induces a signature mutation for oxygen free radical damage. Cancer Res 53:4172-4174, 1993.
56. Feig DI, Reid TM, Loeb LA. Reactive oxygen species in tumorigenesis. Cancer Res 54:1890-1894, 1994.
57. Brash DE, Rudolph JA, Simon JA, et al. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88:10124-10128, 1991.
58. Du MQ, Carmichael PL, Phillips DH. Induction of activating mutations in the human c-Ha-ras-1 proto-oncogene by oxygen free radicals. Mol Carcinog 11:170-175, 1994.