A practical synthesis of SDZ WAG 994 by selective methylation of N6-cyclohexyladenosine

Synthetic Communications

Volumn 26, Issue 21, 1996, Pages 3967-3977

  Prashad, Mahavir ^a   Prasad, Kapa ^a   Repic, Oljan ^a  

^a Sandoz Pharma Ltd   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

6 N CYCLOHEXYL 2' O METHYLADENOSINE; ADENOSINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0029764666     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919608003819     Document Type: Article

References (11)

1. a) Gadient, F., GB 2 226 027 A, June 20, 1990.
2. b) Gadient, F.; Milavec, M.; Muller, E., EP 0 490 818 A1, December 5, 1991.
3. a) Yamada, T.; Kageyama, K., US 4,985,409, January 15, 1991.
4. b) Yamada, T.; Kageyama, K., EP 0 378 518 A2, January 11, 1990.
5. Unpublished results, Chemical R & D, Sandoz Ltd., Basel, Switzerland.
6. a) Robins, M. J.; Naik, S. R.; Lee, A. S. K., J. Org. Chem., 1974, 39, 1891.
7. b) Yamauchi, K.; Nakagima, T.; Kinoshita, M., Bull. Chem. Soc. Jpn., 1986, 59 2947.
8. c) Kazimierczak, Z.; Darzynkiewicz, E.; Shugar, D., Biochemistry. 1976, 15, 2735.
9. Gadient, F., DE 4039060 A1, June 11, 1992.
10. 6-cyclohexyladenosine (unpublished results, Chemical R & D, Sandoz Ltd., Basel). Also see Flevsher. M. H., J. Med.Chem., 1972, 15, 187.
11. Prashad, M.; Prasad, K.; Repic, O., Nucleosides & Nucleotides. 1994, 13, 945.