Are macrophages recovered from mouse lung by bronchoalveolar lavage representative of the alveolar macrophage pool?

Inhalation Toxicology

Volumn 8, Issue 2, 1996, Pages 201-212

  Talbot, R J ^a   Kellington, J P ^a   Morgan, A ^a,b  

^a RICARDO UK LTD   (United Kingdom)

^b Biomedical Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0029764015     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.3109/08958379609046563     Document Type: Article

References (13)

1. Brain, J. D. 1970. The effects of increased particles on the numbers of alveolar macrophages. In Inhaled particles III, ed. W. H. Walton, pp. 200-233. London: Unwin Bros. Ltd.
2. Dahlback, M., and Eirefelt, S. 1994. Total deposition of fluorescent monodisperse particles in rats. In inhaled particles VII, eds. J. Dodgson and R. I. McCallum, Ann. Occup. Hyg. 38(Suppl. 1):127-134.
3. Lehnert, B. E. 1992. Pulmonary and thoracic macrophage subpopulations and clearance from the lung. Environ. Health Perspect. 97:17-46.
4. Lehnert, B. E., Dethloff, L. A., and Valdez, Y. E. 1988. Leukocyte responses to the intrapleural deposition of particles, particle-cell associations, and the clearance of particles from the pleural space compartment. J. Toxicol Environ. Health 24:41-66.
5. Morgan, A., Talbot, R. J., and Taya, A. 1991. Use of fluorescent microspheres in studies of the effects of inhaled radioactive materials on the phagocytic competence of alveolar macrophages. Radiat. Protect. Dosim. 38:205-212.
6. Morgan, A., Kellington, J. P., Morris, K. J., Collier, C. G., and Hodgson, A. 1995. Labeling rat alveolar macrophages with fluorescent microspheres. Inhal. Toxicol. 7:255-267.
7. Mueller, H. L., and Guilmette, R. A. 1987a. Uptake of latex particles by dog alveolar macrophages in vitro - A comparison of monolayer and suspension culture techniques. Inhalation Toxicology Research Institute Annual Report 1986-1987, LMF-120, pp. 122-125.
8. Mueller, H. L., and Guilmette, R. A. 1987b. Early phagocytosis of insoluble particles by rat alveolar macrophages in vivo. Inhalation Toxicology Research Institute Annual Report 1986-1987, LMF-120, pp. 126-132. Albuquerque, NM: Inhalation Toxicology Research Institute.
9. Stober, W., Berner, A., and Blaschke, R. 1969. The aerodynamic diameter of aggregates of uniform spheres. J. Colloid Interface Sci. 29:710-719.
10. Takahashi, S., Kubota, Y., and Hatsuno, H. 1992. Effect of size on the movement of latex particles in the respiratory tract following local administration. Inhal. Toxicol. 4:113-123.
11. Talbot, R. J., Nicholls, A., Morgan, A., and Moores, S. R. 1989. Effect of inhaled α-emitting nuclides on mouse alveolar macrophages. Radiat. Res. 119:271-285.
12. Velasquez, D. J., and Morrow, P. E. 1984. Estimate of guinea-pig tracheobronchial transport rates using a compartment model. Lung Res. 7:163-176.
13. Walsh, M., Pritchard, J. N., Black, A., Moores, S. R., and Morgan, A. 1980. The development of a system for the exposure of rats and mice to aerosols of plutonium oxide. J Aerosol Sci. 11:467-474.