'Pavlovian' food effect on the enterohepatic recirculation of piroxicam

Biopharmaceutics and Drug Disposition

Volumn 17, Issue 7, 1996, Pages 635-641

  Polli, James E ^a,b   Bigora, Sian ^a   Piscitelli, Deborah A ^a   Straughn, Arthur B ^b   Young, David ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Double peak; Enterohepatic recirculation; Food; Piroxicam

Indexed keywords

CHOLECYSTOKININ; PIROXICAM;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG ABSORPTION; DRUG BLOOD LEVEL; FEMALE; FOOD INTAKE; GALLBLADDER EMPTYING; GALLBLADDER FUNCTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; VOLUNTEER;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENTEROHEPATIC CIRCULATION; FEMALE; FOOD; GALLBLADDER; HUMANS; MALE; PIROXICAM; RANDOM ALLOCATION;

EID: 0029763946     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199610)17:7<635::AID-BDD981>3.0.CO;2-4     Document Type: Article

References (18)

1. D. Westerling, L. Frigren and P. Hoglund, Morphine pharmacokinetics and effects on salivation and continuous reaction times in healthy volunteers. Ther. Drug Monit., 15, 364-374 (1993).
2. R. J. Herman, A. Chaudhary and C. B. Szakacs, Disposition of lorazepam in Gilbert's syndrome: effects of fasting, feeding, and enterohepatic circulation. J. Clin. Pharm., 34, 978-984 (1994).
3. W. A. Colburn, Pharmacokinetic analysis of concentration-time data obtained following administration of drugs that are recycled in the bile. J. Pharm. Sci., 73, 313-317 (1984).
4. H. Brunner, T. C. Northfield, A. F. Hofmann, V. L. W. Go and W. H. J. Summerskill, Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Mayo Clin. Proc., 49, 851-860 (1974).
5. G. P. van Berge Henegouwen and A. F. Hofmann, Noctural gallbladder storage and emptying in gallstone patients and healthy subjects. Gastroenterology, 75, 879-885 (1978).
6. G. Palacsiano, P. Portincasa, A. Belfiore, G. Baldassarre and O. Albano, Opposite effects of cholestyramine and loxiglumide on gallbladder dynamics in humans. Gastroenterology, 102, 633-639 (1992).
7. A. J. Vander, J. H. Sherman and D. S. Luciano (Eds), Human Physiology, McGraw-Hill, New York, 1990.
8. M. C. Carey and M. J. Cahalane, Enterohepatic circulation. In The Liver: Biology and Pathobiology, I. M. Irias, W. B. Jakoby, H. Popper, D. Schachter and D. A. Shafritz (Eds), Raven, New York, 1988, pp. 573-616.
9. H. W. Zhou, J. Q. Shen, M. Lu, W. Q. Liang, W. Lin and W. H. Zhao, Pharmacokinetic analysis of enterohepatic circulation of piroxicam in rabbits. Chung-Kuo Yao Li Hsueh Pao-Acta Pharmacol. Sin., 13, 180-182 (1992).
10. D. G. Ferry, L. R. Gazeley, W. J. Busby, D. M. G. Beasley, I. R. Edwards and A. J. Campbell, Enhanced elimination of piroxicam by administration of activated charcoal or cholestyramine. Eur. J. Clin. Pharmacol., 39, 599-601 (1990).
11. T. W. Guentert, R. Defoin and H. Mosberg, The influence of cholestyramine on the elimination of tenoxicam and piroxicam. Eur. J. Clin. Pharmacol., 34, 283-289 (1988).
12. C. Benveniste, R. Striberni and P. Dayer, Indirect assessment of the enterohepatic recirculation of piroxicam and tenoxicam. Eur. J. Clin. Pharmacol., 38, 547-549 (1990).
13. D. A. Piscitelli, S. Bigora, C. Propst, S. Goskonda, L. A. Augsburger and D. Young, The effect of formulation and process changes on in vitro dissolution and the bioequivalence of piroxicam capsules. Pharm. Dev. Technol., to be submitted.
14. I. P. Pavlov, Conditioned Reflexes, Oxford University Press, Oxford, 1927.
15. G. L. Amidon, Personal communication.
16. B. Borgstrom, G. Lundh and A. Hofmann, The site of absorption of conjugated bile salts in man. Gastroenterology, 45, 229-238 (1963).
17. E. R. Schiff, N. C. Small and J. M. Dietschy, Characterization of the kinetics of the passive and active transport mechanisms for bile acid absorption in the small intestine and colon of the rat. J. Clin. Invest., 51, 1351-1362 (1972).
18. E. Krag and S. F. Phillips, Active and passive bile acid absorption in man. J. Clin. Invest., 53, 1686-1694 (1974).