Studies on the chronic oral toxicity of an analgesic drug combination consisting of acetylsalicylic acid, paracetamol and caffeine in rats including an electron microscopical evaluation of kidneys

Arzneimittel-Forschung/Drug Research

Volumn 46, Issue 9, 1996, Pages 895-905

  Lehmann, Horst ^a   Hirsch, Ursula ^a   Bauer, Eckhart ^a   Bauer, Martin ^a   Greischel, Andreas ^a   Schmid, Jochen ^a   Schneider, Peter ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

Author keywords

acetylsalicylic acid; caffeine; CAS 103 90 2; CAS 50 78 2; CAS 58 08 2; paracetamol; Thomapyrin , chronic toxicity studies

Indexed keywords

ACETYLSALICYLIC ACID; ANALGESIC AGENT; APC; CAFFEINE; PARACETAMOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; AUTOPSY; BLOOD CHEMISTRY; CHRONIC TOXICITY; CONTROLLED STUDY; CONVULSION; DRUG BLOOD LEVEL; ELECTRON MICROSCOPY; FEMALE; GOOD LABORATORY PRACTICE; HEMATOLOGY; HISTOPATHOLOGY; KIDNEY MASS; LIVER WEIGHT; MALE; MORTALITY; NEPHROTOXICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; SEX DIFFERENCE; STOMACH EROSION; URINALYSIS;

ACETAMINOPHEN; ANALGESICS; ANIMALS; ASPIRIN; BLOOD CELL COUNT; BODY WEIGHT; CAFFEINE; CENTRAL NERVOUS SYSTEM STIMULANTS; DRUG COMBINATIONS; ENZYMES; FEMALE; KIDNEY DISEASES; MALE; MICROSCOPY, ELECTRON; ORGAN SIZE; RATS; RATS, WISTAR;

EID: 0029763605     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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