A new series of 6-chloro-2,3-dihydro-4(1H)-quinazolinone derivatives as antiemetic and gastointestinal motility enhancing agents

Arzneimittel-Forschung/Drug Research

Volumn 46, Issue 9, 1996, Pages 911-918

  Baldazzi, Claudia ^b   Barbanti, Miriam ^c   Basaglia, Roberta ^a   Benelli, Augusta ^a   Bertolini, Alfio ^a   Piani, Silvano ^b  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b Alfa Wassermann SpA   (Italy)

^c Biological Department   (Italy)

Author keywords

6 chl oro 2,3 dihydro 4(1H) quinazolinones, in vitro and in vivo studies, synthesis; 6 chloro 2,3 dihydro (1H) 1,3 benzoxazin 4 ones; antiemetic drugs; benzamides; prokinetic drugs

Indexed keywords

ANTIEMETIC AGENT; BENZAMIDE DERIVATIVE; CISAPRIDE; CISPLATIN; PROKINETIC AGENT; QUINAZOLINONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIEMETIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; FEMALE; GASTROINTESTINAL MOTILITY; INTESTINE TRANSIT TIME; INTRAVENOUS DRUG ADMINISTRATION; JEJUNUM; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PERISTALSIS; PIGEON; RABBIT; RAT; STOMACH EMPTYING; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIEMETICS; CHEMISTRY, PHYSICAL; CISPLATIN; COLUMBIDAE; FEMALE; GASTRIC EMPTYING; GASTROINTESTINAL MOTILITY; JEJUNUM; MALE; MICE; PERISTALSIS; QUINAZOLINES; RABBITS; RATS; RATS, WISTAR; STIMULATION, CHEMICAL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029763456     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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