Regression of left ventricular hypertrophy in experimental renovascular hypertension: Diastolic dysfunction depends more on myocardial collagen than it does on myocardial mass

Journal of Hypertension

Volumn 14, Issue 9, 1996, Pages 1117-1123

  Dussaillant, Gaston R ^a   Gonzalez, Hernan ^a   Cespedes, Carlos ^a   Jalil, Jorge E ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Diastolic function; Left ventricular hypertrophy; Myocardial collagen

Indexed keywords

ANTIHYPERTENSIVE AGENT; COLLAGEN; ENALAPRIL; HYDROXYPROLINE; LOSARTAN;

ANIMAL EXPERIMENT; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CONTROLLED STUDY; DIASTOLE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE; NONHUMAN; PRIORITY JOURNAL; RAT; RENOVASCULAR HYPERTENSION;

EID: 0029763059     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004872-199609000-00012     Document Type: Article

References (45)

1. Levy D, Labib SB, Anderson KM, Christiansen JC, Kannel WB, Castelli WP: Determinants of sensitivity and specificity of electrocardiographs criteria for left ventricular hypertroply. Circulation 1990, 81:815-820.
2. Kannel WB, Sorlie P: Left ventricular hypertrophy in hypertension: Prognostic and pathogenetic implications (The Framingham study). In The Heart in Hypertension. Edited by Strauer BE. Berlin: Springer-Verlag: 1981:223.
3. Brilla CG, Pick R, Tan LB, Janicki JS, Weber KT: Remodeling of the rat right and left ventricles in experimental hypertension. Circ Res 1990, 67:1355-1364.
4. Morgan HE, Baker KM: Cardiac hypertrophy. Mechanical, neural and endocrine dependence. Circulation 1991, 83:13-25.
5. Weber KT, Brilla CG: Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system. Circulation 1991, 83:1849-1865.
6. Linz W, Scholkens BA, Ganten D: Converting enzyme inhibition specifically prevents the development and induces regression of cardiac hypertrophy in rats. Clin Exp Hypertens [A] 1989, 11: 1325-1350.
7. Jalil JE, Doering CW, Janicki JS, Pick R, Weber KT: Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle. Circ Res 1989, 64:1041-1050.
8. Weber KT, Brilla CG, Janicki JS: Structural remodeling of myocardial collagen in systemic hypertension: functional consequences and potential therapy. Heart Failure 1990, 6:129-137.
9. Koren MJ, Savage DD, Casale PN, Laragh JH, Devereux RB: Changes in left ventricular mass predict risk in essential hypertension [abstract]. Circulation 1990, 82 (suppl III):III398.
10. Brilla CG, Weber KT: Prevention of myocardial fibrosis in hypertension: Role of fibroblast corticoid receptors and spironolactone [abstract]. FASEB J 1991, 5:A1256.
11. Narayan S, Janicki JS, Schroff SG, Pick R, Weber KT: Myocardial collagen and mechanics after preventing hypertrophy in hypertensive rats. Am J Hypertens 1989, 2:675-682.
12. Turner JE, Oliver MH, Guerreiro D, Laurent GJ: Collagen metabolism during right ventricular hypertrophy following induced lung injury. Am J Physiol 1986, 251:H915-H919.
13. Ruskoaho HJ, Savolainen ER: Effects of long-term verapamil treatment on blood pressure, cardiac hypertrophy and collagen metabolism in spontaneously hypertensive rats. Cardiovasc Res 1985, 19:355-362.
14. Sen S, Tarazi RC, Bumpus FM: Reversal of cardiac hypertrophy in renal hypertensive rats: medical vs surgical therapy. Am J Physiol 1981, 240: H408-H412.
15. Weber KT, Anversa P, Armstrong PW, Brilla CG, Burnett JC, Cruickshank JM, et al.: Remodeling and reparation of the cardiovascular system. J Am Coll Cardiol 1992, 20:3-16.
16. Brilla CG, Janicki JS, Weber KT: Impaired diastolic function and coronary reserve in genetic hypertension. Circ Res 1991, 69:107-115.
17. Timmermans PBMWH, Carini DJ, Chiu AT, Duncia JV, Price WA, Wells GJ, et al.: The discovery of a new class of highly specific nonpeptide angiotensin II receptor antagonists. Am J Hypertens 1991, 4: 275S-281S.
18. Wong PC, Price WA, Chiu AT, Duncia JV, Carini DJ, Wexler RR, et al.: In vivo pharmacology of DUP 753. Am J Hypertens 1991, 4:288S-298S.
19. Erdos EG, Skidgel RA: The angiotensin I-converting enzyme. Lab Invest 1987, 56:345-348.
20. Lovenberg W: Techniques for the measurement of blood pressure. Hypertension 1987, 9:15-16.
21. Weber KT, Janicki JS, Schroff SG: Measurement of ventricular function in the experimental laboratory. In The Heart and Cardiovascular System. Edited by Fozzard HA, et al. New York: Raven Press: 1986.
22. Doering CW, Jalil JE, Janicki JS, Pick R, Aghili S, Abrahams C, Weber KT: Collagen network remodeling and diastolic stiffness of the rat left ventricle with pressure overloaded hypertrophy. Cardiovasc Res 1988, 22:686-695.
23. Jalil JE, Janicki JS, Pick R, Weber KT: Coronary vascular remodeling and myocardial fibrosis in the rat with renovascular hypertension: response to captopril. Am J Hypertens 1991, 4:51-55.
24. Jalil JE, Janicki JS, Pick R, Abrahams C, Weber KT: Fibrosis-induced reduction of endomyocardium in the rat after isoproterenol treatment. Circ Res 1989, 65:256-264.
25. Weber KT, Janicki JS, Schroff SG, Pick R, Chen RM, Bashey RI: Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium. Circ Res 1988, 62:757-765.
26. Bergman I, Roxley R: Two improved and simplified methods for the determination of hydroxyproline. Anal Chem 1963, 35:1961-1965.
27. Junqueira LCU, Bignolas G, Brentani RR: Picrosirius staining plus polarization microscpoy, a specific method for collagen detection in tissue sections. Histochem J 1979, 11:447-455.
28. Gujarati D: Use of dummy variables in testing for equality between sets of coefficients in linear regression: a generalization. Am Statist 1970, 24:18-22.
29. Camargo MJ, von Lutterotti N, Pecker MS, James GD, Timmermans PBMWH, Laragh JH: DuP 753 increases survival in spontaneously hypertensive stroke-prone rats fed a high sodium diet. Am J Hypertens 1991, 4:341S-345S.
30. Schudeck R, Jalil JE, Vio C, Nalli A, Céspedes C, Ebensperger R: Regression of renal fibrosis and damage in experimental renovascular hypertension using an angiotensin type 1 receptor antagonist [abstract]. J Am Coll Cardiol 1994, suppl 1A:332.
31. Nicoletti A, Heudes D, Hinglais N, Appay M-D, Philippe M, Sassy-Prigent C, et al: Left ventricular fibrosis in renovascular hypertensive rats. Effect of losartan and spironolactone. Hypertension 1995, 26:101-111.
32. Brilla CHG, Weber KT: Reactive and reparative myocardial fibrosis in arterial hypertension in the rat. Cardiovasc Res 1992, 26:671-677
33. Minglais N, Mendes D, Nicoletti A, Maudet CH, Laenent M, Banety J, et al.: Colocalization of myocardial fibrosis and inflammatory cells in rats. Lab Invest 1994, 70:286-294.
34. Gohlke P, Linz W, Schölkens BA, Kuwer I, Bartenbach S, Schnell A, et al.: Angiotensin-converting enzyme inhibition improves cardiac function, role of bradykinin. Hypertension 1994, 23:411-418.
35. Schraeger JA, Canby CA, Rongish BJ, Kawai M, Tomanek RJ: Normal left ventricular diastolic compliance after regression of hypertrophy. J Cardiovasc Pharm 1994, 23:349-357.
36. Michel JB, Sayah S, Nussberger J, Guettier C, Philippe M, Galen FX, et al.: Physiological and immunopathological consequences of active immunization of spontaneously hypertensive and normotensive rats against murine renin. Circulation 1990, 81:1899-1910.
37. Weber KT, Pick R, Jalil JE, Janicki JS, Carroll EP: Patterns of myocardial fibrosis. J Moll Cell Cardiol 1989, 21:121-131.
38. Tan LP, Jalil JE, Pick R, Janicki JS, Weber KT: Cardiac myocyte necrosis induced by angiotensin II. Circ Res 1991, 69:1185-1195.
39. Sen S, Bumpus FM: Collagen synthesis in development and reversal of cardiac hypertrophy in spontaneously hypertensive rats. Am J Cardiol 1979, 44:954-958.
40. Conrad CH, Brooks WW, Hayes JA, Sen S, Robinson KG, Bing OHL: Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat Circulation 1995, 91:161-170.
41. MacKenna DA, Omens JH, McCulloh AD, Covell JW: Contribution of collagen matrix to passive left ventricular mechanics in isolated rat hearts. Am J Physiol 1994, 266:H1007-H1018
42. Jalil JE, Doering CW, Janicki JS, Pick R, Clark WA, Weber KT: Structural vs contractile protein remodeling and myocardial stiffness in hypertrophied rat left ventricle. J Moll Cell Cardiol 1988, 20:1179-1187.
43. Carroll EP, Janicki JS, Pick R, Weber KT: Myocardial stiffness and reparative fibrosis following coronary embolization in the rat Cardiovasc Res 1989, 23:655-661.
44. Capasso JM, Palackal T, Olivetti G, Anversa P: Left ventricular failure induced by long-term hypertension in rats. Circ Res 1990, 66: 1400-1412.
45. Weber KT, Brilla CHG, Janicki JS: Myocardial fibrosis: functional significance and regulatory factors. Cardiovasc Res 1993, 27:341-348.