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Volumn 28, Issue 2, 1996, Pages 177-182

Effect of long-term treatment with propionyl-L-carnitine on smooth muscle cell polyploidy in spontaneously hypertensive rats

Author keywords

antihypertensive agents; polyploidy; propionyl L carnitine; rats, inbred SHR

Indexed keywords

CARNITINE DERIVATIVE;

EID: 0029763038     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.HYP.28.2.177     Document Type: Article
Times cited : (11)

References (41)
  • 1
    • 0017688365 scopus 로고
    • Morphometric analysis of hypertension-induced hypertrophy of rat thoracic aorta
    • Wiener J, Loud AV, Giacomelli F, Anversa P. Morphometric analysis of hypertension-induced hypertrophy of rat thoracic aorta. Am J Pathol. 1977;88:619-634.
    • (1977) Am J Pathol. , vol.88 , pp. 619-634
    • Wiener, J.1    Loud, A.V.2    Giacomelli, F.3    Anversa, P.4
  • 3
    • 0019953347 scopus 로고
    • Quantitative structural changes of the rat thoracic aorta in early spontaneous hypertension
    • Olivetti G, Melissari M, Marchetti G, Anversa P. Quantitative structural changes of the rat thoracic aorta in early spontaneous hypertension. Circ Res. 1982;51:19-26.
    • (1982) Circ Res. , vol.51 , pp. 19-26
    • Olivetti, G.1    Melissari, M.2    Marchetti, G.3    Anversa, P.4
  • 4
    • 0020587363 scopus 로고
    • Morphometric study of structural changes in the mesenteric blood vessels of spontaneously hypertensive rats
    • Lee RMKW, Garfield RE, Forrest JB, Daniel EE. Morphometric study of structural changes in the mesenteric blood vessels of spontaneously hypertensive rats. Blood Vessels. 1983;20:57-71.
    • (1983) Blood Vessels , vol.20 , pp. 57-71
    • Lee, R.M.K.W.1    Garfield, R.E.2    Forrest, J.B.3    Daniel, E.E.4
  • 5
    • 0019960870 scopus 로고
    • Alterations in vascular smooth muscle mass in spontaneously hypertensive rat: Role in cellular hypertrophy, hyperploidy and hyperplasia
    • Owens GK, Schwartz SM. Alterations in vascular smooth muscle mass in spontaneously hypertensive rat: role in cellular hypertrophy, hyperploidy and hyperplasia. Circ Res. 1982;51:280-289.
    • (1982) Circ Res. , vol.51 , pp. 280-289
    • Owens, G.K.1    Schwartz, S.M.2
  • 6
    • 0022383037 scopus 로고
    • Hyperplastic growth response of vascular smooth muscle cells following induction of acute hypertension in rats by aortic coarctation
    • Owens GK, Reidy MA. Hyperplastic growth response of vascular smooth muscle cells following induction of acute hypertension in rats by aortic coarctation. Circ Res. 1985;57:695-705.
    • (1985) Circ Res. , vol.57 , pp. 695-705
    • Owens, G.K.1    Reidy, M.A.2
  • 7
    • 0023653621 scopus 로고
    • The arterial smooth muscle cell in systemic hypertension
    • Chobanian AV. The arterial smooth muscle cell in systemic hypertension. Am J Cardiol. 1987;60:94I-98I.
    • (1987) Am J Cardiol. , vol.60
    • Chobanian, A.V.1
  • 8
    • 0021064462 scopus 로고
    • Vascular smooth muscle cell hypertrophy and hyperploidy in Goldblatt hypertensive rat
    • Owens GK, Schwartz SM. Vascular smooth muscle cell hypertrophy and hyperploidy in Goldblatt hypertensive rat. Circ Res. 1983;53: 491-501.
    • (1983) Circ Res. , vol.53 , pp. 491-501
    • Owens, G.K.1    Schwartz, S.M.2
  • 9
    • 84940637298 scopus 로고
    • Does smooth muscle cell polyploidy occur in resistance vessels of spontaneously hypertensive rats?
    • Black MJ, Campbell JH, Campbell GR. Does smooth muscle cell polyploidy occur in resistance vessels of spontaneously hypertensive rats? Blood Vessels. 1988;25:89-100.
    • (1988) Blood Vessels , vol.25 , pp. 89-100
    • Black, M.J.1    Campbell, J.H.2    Campbell, G.R.3
  • 10
    • 0027740061 scopus 로고
    • Renin-dependent hypertension induces smooth muscle polyploidy in large and small vessels
    • Black MJ, Dilley RJ, Bobik A. Renin-dependent hypertension induces smooth muscle polyploidy in large and small vessels. J Hypertens. 1993;11(suppl 5):S118-S119.
    • (1993) J Hypertens. , vol.11 , Issue.5 SUPPL.
    • Black, M.J.1    Dilley, R.J.2    Bobik, A.3
  • 11
    • 0022615306 scopus 로고
    • Replication in smooth muscle cells in vascular disease
    • Schwartz S, Campbell G, Campbell J. Replication in smooth muscle cells in vascular disease. Circ Res. 1986;58:427-444.
    • (1986) Circ Res. , vol.58 , pp. 427-444
    • Schwartz, S.1    Campbell, G.2    Campbell, J.3
  • 13
    • 0025813542 scopus 로고
    • Vascular smooth muscle cell proliferation and its therapeutic modulation in hypertension
    • Hadrava V, Kruppa U, Russo RC, Lacourcière Y, Tremblay J, Hamet P. Vascular smooth muscle cell proliferation and its therapeutic modulation in hypertension. Am Heart J. 1991;122:1198-1203.
    • (1991) Am Heart J. , vol.122 , pp. 1198-1203
    • Hadrava, V.1    Kruppa, U.2    Russo, R.C.3    Lacourcière, Y.4    Tremblay, J.5    Hamet, P.6
  • 14
    • 0021917072 scopus 로고
    • Differential effects of antihypertensive drug therapy on vascular smooth muscle cell hypertrophy, hyperploidy, and hyperplasia in the spontaneously hypertensive rat
    • Owens GK. Differential effects of antihypertensive drug therapy on vascular smooth muscle cell hypertrophy, hyperploidy, and hyperplasia in the spontaneously hypertensive rat. Circ Res. 1985;56: 525-536.
    • (1985) Circ Res. , vol.56 , pp. 525-536
    • Owens, G.K.1
  • 15
    • 0023101515 scopus 로고
    • Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats
    • Owens GK. Influence of blood pressure on development of aortic medial smooth muscle hypertrophy in spontaneously hypertensive rats. Hypertension. 1987;9:178-187.
    • (1987) Hypertension , vol.9 , pp. 178-187
    • Owens, G.K.1
  • 16
    • 0024906472 scopus 로고
    • Effect of enalapril on aortic smooth muscle cell polyploidy in the spontaneously hypertensive rat
    • Black MJ, Adams MA, Bobik A, Campbell JH, Campbell GR. Effect of enalapril on aortic smooth muscle cell polyploidy in the spontaneously hypertensive rat. J Hypertens. 1989;7:997-1003.
    • (1989) J Hypertens. , vol.7 , pp. 997-1003
    • Black, M.J.1    Adams, M.A.2    Bobik, A.3    Campbell, J.H.4    Campbell, G.R.5
  • 17
    • 0023181521 scopus 로고
    • Inhibition of nuclear polyploidy by propranolol in aortic smooth muscle cells of hypertensive rats
    • Leitschuh AH, Chobanian AV. Inhibition of nuclear polyploidy by propranolol in aortic smooth muscle cells of hypertensive rats. Hypertension. 1987;9(suppl III):III-106-III-109.
    • (1987) Hypertension , vol.9 , Issue.3 SUPPL.
    • Leitschuh, A.H.1    Chobanian, A.V.2
  • 18
    • 0023121614 scopus 로고
    • Effects of deoxycorticosterone/salt hypertension on cell ploidy in rat aortic smooth muscle cells
    • Chobanian AV, Lichtenstein AH, Schwartz JH, Hanspal J, Brecher P. Effects of deoxycorticosterone/salt hypertension on cell ploidy in rat aortic smooth muscle cells. Circulation. 1987;75(suppl I): I-102-I-106.
    • (1987) Circulation , vol.75 , Issue.1 SUPPL.
    • Chobanian, A.V.1    Lichtenstein, A.H.2    Schwartz, J.H.3    Hanspal, J.4    Brecher, P.5
  • 19
  • 20
    • 0025794240 scopus 로고
    • Biochemical profile of propionyl-L-carnitine
    • Hulsman WC. Biochemical profile of propionyl-L-carnitine. Cardiovasc Drugs Ther. 1991;5(suppl 1):7-10.
    • (1991) Cardiovasc Drugs Ther. , vol.5 , Issue.1 SUPPL. , pp. 7-10
    • Hulsman, W.C.1
  • 21
    • 85047675973 scopus 로고
    • Protection of the ischaemic myocardium by L-propionylcarnitine: Effects on the recovery of cardiac output after ischaemia and reperfusion, carnitine transport, and fatty acid oxidation
    • Paulson DJ, Traxler J, Schmidt M, Noonam J, Shug AL. Protection of the ischaemic myocardium by L-propionylcarnitine: effects on the recovery of cardiac output after ischaemia and reperfusion, carnitine transport, and fatty acid oxidation. Cardiovasc Res. 1986; 20:536-541.
    • (1986) Cardiovasc Res. , vol.20 , pp. 536-541
    • Paulson, D.J.1    Traxler, J.2    Schmidt, M.3    Noonam, J.4    Shug, A.L.5
  • 23
    • 0025891788 scopus 로고
    • The effect of propionyl-L-camitine on the ischemic and reperfused intact myocardium and their derived mitochondria
    • Ferrari R, Ceconi C, Cargnoni A, Pasini E, Boffa GM, Curello S, Visioli O. The effect of propionyl-L-camitine on the ischemic and reperfused intact myocardium and their derived mitochondria. Cardiovasc Drugs Ther. 1991;5(suppl 1):57-66.
    • (1991) Cardiovasc Drugs Ther. , vol.5 , Issue.1 SUPPL. , pp. 57-66
    • Ferrari, R.1    Ceconi, C.2    Cargnoni, A.3    Pasini, E.4    Boffa, G.M.5    Curello, S.6    Visioli, O.7
  • 24
    • 0025810473 scopus 로고
    • Effect of propionyl-L-carnitine on L-type calcium channel in human heart sarcolemma
    • Bevilacqua M, Vago T, Norbiato G. Effect of propionyl-L-carnitine on L-type calcium channel in human heart sarcolemma. Cardiovasc Drues Ther. 1991;5(suppl 1):31-36.
    • (1991) Cardiovasc Drues Ther. , vol.5 , Issue.1 SUPPL. , pp. 31-36
    • Bevilacqua, M.1    Vago, T.2    Norbiato, G.3
  • 25
    • 0025804736 scopus 로고
    • Effect of propionyl-L-carnitine on human endothelial cells
    • Van Hinsbergh VWM, Scheffer MA. Effect of propionyl-L-carnitine on human endothelial cells. Cardiovasc Drugs Ther. 1991;5(suppl 1):97-106.
    • (1991) Cardiovasc Drugs Ther. , vol.5 , Issue.1 SUPPL. , pp. 97-106
    • Van Hinsbergh, V.W.M.1    Scheffer, M.A.2
  • 27
    • 0022344972 scopus 로고
    • Some practical considerations in quantitative absorbance microspectrophotometry
    • Mikel UV, Fishbein WN, Bahr GF. Some practical considerations in quantitative absorbance microspectrophotometry. Anal Quant Cytol Histol. 1985;7:107-118.
    • (1985) Anal Quant Cytol Histol. , vol.7 , pp. 107-118
    • Mikel, U.V.1    Fishbein, W.N.2    Bahr, G.F.3
  • 28
    • 0027054853 scopus 로고
    • Incidence of multinucleated and polyploid aortic smooth muscle cells cultured from different age groups of spontaneously hypertensive rats
    • Lee RMKW, Conyers RB, Kwan CY. Incidence of multinucleated and polyploid aortic smooth muscle cells cultured from different age groups of spontaneously hypertensive rats. Can J Physiol Pnarmacol. 1992;70:1496-1501.
    • (1992) Can J Physiol Pnarmacol. , vol.70 , pp. 1496-1501
    • Lee, R.M.K.W.1    Conyers, R.B.2    Kwan, C.Y.3
  • 30
    • 0025966262 scopus 로고
    • Extraction of DNA from paraffin blocks for southern blot analysis
    • Mies C, Houldsworth J, Chaganti RSK. Extraction of DNA from paraffin blocks for southern blot analysis. Am J Surg Pathol. 1991; 15:169-174.
    • (1991) Am J Surg Pathol. , vol.15 , pp. 169-174
    • Mies, C.1    Houldsworth, J.2    Chaganti, R.S.K.3
  • 32
    • 0024514941 scopus 로고
    • Ploidy in mesenteric vessels of aged spontaneously hypertensive and Wistar-Kyoto rats
    • Lombardi DM, Owens GK, Schwartz SM. Ploidy in mesenteric vessels of aged spontaneously hypertensive and Wistar-Kyoto rats. Hypertension. 1989;13:475-479.
    • (1989) Hypertension , vol.13 , pp. 475-479
    • Lombardi, D.M.1    Owens, G.K.2    Schwartz, S.M.3
  • 33
    • 0023711123 scopus 로고
    • Cell biology of vascular hypertrophy in systemic hypertension
    • Dzau VJ, Gibbons GH. Cell biology of vascular hypertrophy in systemic hypertension. Am J Cardiol. 1988;62:30G-35G.
    • (1988) Am J Cardiol. , vol.62
    • Dzau, V.J.1    Gibbons, G.H.2
  • 34
    • 0024793652 scopus 로고
    • Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells
    • Owens GK. Control of hypertrophic versus hyperplastic growth of vascular smooth muscle cells. Am J Physiol. 1989;257:H1755-H1765.
    • (1989) Am J Physiol. , vol.257
    • Owens, G.K.1
  • 36
    • 0021270640 scopus 로고
    • Inositol triphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor
    • Berridge MJ, Heslop JP, Irvine RF, Brown KD. Inositol triphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor. Biochem J. 1984;222:195-201.
    • (1984) Biochem J. , vol.222 , pp. 195-201
    • Berridge, M.J.1    Heslop, J.P.2    Irvine, R.F.3    Brown, K.D.4
  • 38
    • 0021328588 scopus 로고
    • Changes in calmodulin and its mRNA accompany re-entry of quiescent (G0) cells into the cell cycle
    • Chafouleas JG, Lagace L, Bolton WE, Boyd AE, Means AR. Changes in calmodulin and its mRNA accompany re-entry of quiescent (G0) cells into the cell cycle. Cell. 1984;36:73-81.
    • (1984) Cell , vol.36 , pp. 73-81
    • Chafouleas, J.G.1    Lagace, L.2    Bolton, W.E.3    Boyd, A.E.4    Means, A.R.5
  • 39
    • 0017857391 scopus 로고
    • Calcium leakage as a cause of the high resting tension in vascular muscle from the spontaneously hypertensive rat
    • Noon JP, Rice PJ, Baldessarini RJ. Calcium leakage as a cause of the high resting tension in vascular muscle from the spontaneously hypertensive rat. Proc Natl Acad Sci U S A. 1978;75:1605-1607.
    • (1978) Proc Natl Acad Sci U S A , vol.75 , pp. 1605-1607
    • Noon, J.P.1    Rice, P.J.2    Baldessarini, R.J.3
  • 41
    • 0021213870 scopus 로고
    • Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene
    • Greenberg ME, Ziff EB. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature. 1984;311:433-437.
    • (1984) Nature , vol.311 , pp. 433-437
    • Greenberg, M.E.1    Ziff, E.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.