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Volumn 74, Issue 7, 1996, Pages 393-400

Low plasma glutamine in combination with high glutamate levels indicate risk for loss of body cell mass in healthy individuals: The effect of N- acetyl-cysteine

Author keywords

Anaerobic exercise; Body cell mass; Cachexia; Cysteine effect on BCM; N Acetyl cysteine effect on body cell mass

Indexed keywords

ACETYLCYSTEINE; GLUTAMIC ACID; GLUTAMINE;

EID: 0029762379     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00210633     Document Type: Article
Times cited : (50)

References (51)
  • 1
    • 0027497292 scopus 로고
    • Protein and amino acid metabolism in cancer cachexia: Investigative techniques and therapeutic interventions
    • Pisters PW, Pearlstone DB (1993) Protein and amino acid metabolism in cancer cachexia: investigative techniques and therapeutic interventions. Crit Rev in Clin Lab Sciences 30:223-272
    • (1993) Crit Rev in Clin Lab Sciences , vol.30 , pp. 223-272
    • Pisters, P.W.1    Pearlstone, D.B.2
  • 2
    • 0022552334 scopus 로고
    • Malnutrition in patients with gastrointestinal malignancy. Significance and management
    • Brennan MF (1986) Malnutrition in patients with gastrointestinal malignancy. Significance and management. Dig Dis Sci 31:77S-90S
    • (1986) Dig Dis Sci , vol.31
    • Brennan, M.F.1
  • 3
    • 0018665420 scopus 로고
    • Cancer cachexia in man. A review
    • Strain AJ (1979) Cancer cachexia in man. A review. Invest Cell Pathol 2:181-193
    • (1979) Invest Cell Pathol , vol.2 , pp. 181-193
    • Strain, A.J.1
  • 4
    • 0018949428 scopus 로고
    • Prognostic effect of weight loss prior to chemotherapy in cancer patients
    • DeWys WD, Begg C, Lavin PT et al (1980) Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am J Med 69:491-497
    • (1980) Am J Med , vol.69 , pp. 491-497
    • DeWys, W.D.1    Begg, C.2    Lavin, P.T.3
  • 5
    • 0344052825 scopus 로고
    • Mechanisms of wasting in infection and cancer: An approach to cachexia in AIDS
    • Kotler DP (ed) Raven, New York
    • Grunfeld C (1991) Mechanisms of wasting in infection and cancer: an approach to cachexia in AIDS. In: Kotler DP (ed) Gastrointestinal and nutritional manisfestions of AIDS. Raven, New York, pp 207-229
    • (1991) Gastrointestinal and Nutritional Manisfestions of AIDS , pp. 207-229
    • Grunfeld, C.1
  • 6
    • 0022337811 scopus 로고
    • Body composition in patients with the acquired immunodeficiency syndrome
    • Kotler DP, Wang J, Pierson R (1985) Body composition in patients with the acquired immunodeficiency syndrome. Am J Clin Nutr 42:1255-1265
    • (1985) Am J Clin Nutr , vol.42 , pp. 1255-1265
    • Kotler, D.P.1    Wang, J.2    Pierson, R.3
  • 7
    • 0017697458 scopus 로고
    • Uncomplicated starvation versus cancer cachexia
    • Brennan MF (1977) Uncomplicated starvation versus cancer cachexia. Cancer Res 37:2359-2364
    • (1977) Cancer Res , vol.37 , pp. 2359-2364
    • Brennan, M.F.1
  • 8
    • 0017261887 scopus 로고
    • Parenteral nutrition in the septic patient: Nitrogen balance, limiting plasma amino acids, and calorie to nitrogen ratios
    • Long CL, Crosby F, Geiger JW, Kinney JM (1976) Parenteral nutrition in the septic patient: nitrogen balance, limiting plasma amino acids, and calorie to nitrogen ratios. Am J Clin Nutr 29:380-391
    • (1976) Am J Clin Nutr , vol.29 , pp. 380-391
    • Long, C.L.1    Crosby, F.2    Geiger, J.W.3    Kinney, J.M.4
  • 9
    • 0022348674 scopus 로고
    • Adenocarcinoma of the esophagus and gastroesophageal junction: Prognostic factors and results of therapy
    • Fein R, Kelsen DP, Geller N (1985) Adenocarcinoma of the esophagus and gastroesophageal junction: prognostic factors and results of therapy. Cancer 56:2512-2518
    • (1985) Cancer , vol.56 , pp. 2512-2518
    • Fein, R.1    Kelsen, D.P.2    Geller, N.3
  • 10
    • 0000654568 scopus 로고
    • The immediate causes of death in cancer
    • Warren S (1932) The immediate causes of death in cancer. Am J Med Sci 184:610-615
    • (1932) Am J Med Sci , vol.184 , pp. 610-615
    • Warren, S.1
  • 13
    • 0023224877 scopus 로고
    • Is wasting itself lethal? A case-control prospective study
    • Friedman PJ (1987) Is wasting itself lethal? A case-control prospective study. Nutr Res 7:707-717
    • (1987) Nutr Res , vol.7 , pp. 707-717
    • Friedman, P.J.1
  • 14
    • 0018354892 scopus 로고
    • Gluconeogenesis from alanine in patients with progressive malignant disease
    • 1968
    • Waterhouse C, Jeanpretre N, Kielson J (1968) Gluconeogenesis from alanine in patients with progressive malignant disease. Cancer Res 39: (1968)
    • (1968) Cancer Res , vol.39
    • Waterhouse, C.1    Jeanpretre, N.2    Kielson, J.3
  • 16
    • 0021800976 scopus 로고
    • Assessment of alanine, urea and glucose interrelationships in normal subjects and in patients with sepsis using stable isotopic tracers
    • Shaw JHF, Klein S, Wolfe RR (1985) Assessment of alanine, urea and glucose interrelationships in normal subjects and in patients with sepsis using stable isotopic tracers. Surgery 97:557-567
    • (1985) Surgery , vol.97 , pp. 557-567
    • Shaw, J.H.F.1    Klein, S.2    Wolfe, R.R.3
  • 17
    • 0015440697 scopus 로고
    • Hormonal regulation of glutamine metabolism in fasting man
    • Aoki T, Muller WA, Cahill GF (1972) Hormonal regulation of glutamine metabolism in fasting man. Adv Enzyme Regul 10:145-151
    • (1972) Adv Enzyme Regul , vol.10 , pp. 145-151
    • Aoki, T.1    Muller, W.A.2    Cahill, G.F.3
  • 21
    • 0026875162 scopus 로고
    • Plasma amino acid patterns in cancer
    • Zhang PC, Pang CP (1992) Plasma amino acid patterns in cancer. Clin Chem 38:1198-1199
    • (1992) Clin Chem , vol.38 , pp. 1198-1199
    • Zhang, P.C.1    Pang, C.P.2
  • 23
    • 0344832000 scopus 로고
    • Abnormal amino acid concentrations in the blood of patients with acquired immune deficiency syndrome (AIDS) may contribute to the immunological defect
    • Droge W, Eck H-P, Näher H, Pekar U, Daniel V (1988) Abnormal amino acid concentrations in the blood of patients with acquired immune deficiency syndrome (AIDS) may contribute to the immunological defect. Biol Chem Hoppe-Seyler 369:143-148
    • (1988) Biol Chem Hoppe-Seyler , vol.369 , pp. 143-148
    • Droge, W.1    Eck, H.-P.2    Näher, H.3    Pekar, U.4    Daniel, V.5
  • 24
    • 0028273476 scopus 로고
    • Changes in plasma amino acid concentrations in response to HIV-1 infection
    • Hortin GL, Landt M, Powderly WG. (1994) Changes in plasma amino acid concentrations in response to HIV-1 infection. Clin Chem 40:785-789
    • (1994) Clin Chem , vol.40 , pp. 785-789
    • Hortin, G.L.1    Landt, M.2    Powderly, W.G.3
  • 26
    • 0018509261 scopus 로고
    • Physiological and metabolic correlations in human sepsis
    • Siegel JH, Cerra FB, Coleman B et al (1979) Physiological and metabolic correlations in human sepsis. Surgery 86:163-192
    • (1979) Surgery , vol.86 , pp. 163-192
    • Siegel, J.H.1    Cerra, F.B.2    Coleman, B.3
  • 27
    • 0019179123 scopus 로고
    • Septic autocannibalism: A failure of exogenous nutritional support
    • Cerra FB, Siegel JH, Coleman B (1980) Septic autocannibalism: a failure of exogenous nutritional support. Ann Surg 192:570-574
    • (1980) Ann Surg , vol.192 , pp. 570-574
    • Cerra, F.B.1    Siegel, J.H.2    Coleman, B.3
  • 29
    • 0025314287 scopus 로고
    • Glutamine-ennched diets support muscle glutamine metabolism without stimulating tumor growth
    • Klimberg VS, Souba WW, Salloum RM et al (1990) Glutamine-ennched diets support muscle glutamine metabolism without stimulating tumor growth. J Surg Res 48:319-323
    • (1990) J Surg Res , vol.48 , pp. 319-323
    • Klimberg, V.S.1    Souba, W.W.2    Salloum, R.M.3
  • 31
    • 0024492090 scopus 로고
    • Effect of patenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery
    • Stehle P, Mertes N, Puchstein Ch, Zander J, Albers S, Lawin P (1989) Effect of patenteral glutamine peptide supplements on muscle glutamine loss and nitrogen balance after major surgery. Lancet 1:231-233
    • (1989) Lancet , vol.1 , pp. 231-233
    • Stehle, P.1    Mertes, N.2    Puchstein, Ch.3    Zander, J.4    Albers, S.5    Lawin, P.6
  • 32
    • 0024580521 scopus 로고
    • Addition of glutamine to total parenteral nutrition after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis, and improves nitrogen balance
    • Hammarqvist F, Wernerman J, Ali R, von der Decken A, Vinnars E (1989) Addition of glutamine to total parenteral nutrition after elective abdominal surgery spares free glutamine in muscle, counteracts the fall in muscle protein synthesis, and improves nitrogen balance. Ann Surg 209:455-461
    • (1989) Ann Surg , vol.209 , pp. 455-461
    • Hammarqvist, F.1    Wernerman, J.2    Ali, R.3    Von Der Decken, A.4    Vinnars, E.5
  • 34
    • 0026769166 scopus 로고
    • A review of cancer cachexia and abnormal glucose metabolism in humans with cancer
    • Tayek JA (1992) A review of cancer cachexia and abnormal glucose metabolism in humans with cancer. J Am Col Nutr. 11:445-456
    • (1992) J Am Col Nutr. , vol.11 , pp. 445-456
    • Tayek, J.A.1
  • 35
    • 0018221089 scopus 로고
    • Metabolic changes in burned patients
    • Wilmore DW, Aulick LH (1978) Metabolic changes in burned patients. Surg Clin North Am 58:1173-1187
    • (1978) Surg Clin North Am , vol.58 , pp. 1173-1187
    • Wilmore, D.W.1    Aulick, L.H.2
  • 36
    • 0022309152 scopus 로고
    • Untersuchungen zum Aminosäuren- und Proteinstoffwechsel bei kritisch Kranken
    • Roth E (1985) Untersuchungen zum Aminosäuren- und Proteinstoffwechsel bei kritisch Kranken. Infusionstherapie 12:270-280
    • (1985) Infusionstherapie , vol.12 , pp. 270-280
    • Roth, E.1
  • 37
    • 0024842942 scopus 로고
    • Plasma glutamate levels, lymphocyte reactivity and death rate in patients with bronchial carcinoma
    • Eck H-P, Drings P, Droge W (1989) Plasma glutamate levels, lymphocyte reactivity and death rate in patients with bronchial carcinoma. J Cancer Clin Oncol 115:571-574
    • (1989) J Cancer Clin Oncol , vol.115 , pp. 571-574
    • Eck, H.-P.1    Drings, P.2    Droge, W.3
  • 38
    • 0025923094 scopus 로고
    • Metabolic disorder as an early consequence of simian immunodeficiency virus infection in rhesus macaques
    • Eck H-P, Stahl-Hennig C, Hunsmann G, Droge W (1991) Metabolic disorder as an early consequence of simian immunodeficiency virus infection in rhesus macaques. Lancet 338:346-347
    • (1991) Lancet , vol.338 , pp. 346-347
    • Eck, H.-P.1    Stahl-Hennig, C.2    Hunsmann, G.3    Droge, W.4
  • 39
    • 0023617392 scopus 로고
    • Abnormal glutamate metabolism in amyotrophic lateral sclerosis
    • Plaitakis A, Caroscio JT (1987) Abnormal glutamate metabolism in amyotrophic lateral sclerosis. Ann Neurol 22:575-579
    • (1987) Ann Neurol , vol.22 , pp. 575-579
    • Plaitakis, A.1    Caroscio, J.T.2
  • 40
    • 0029882282 scopus 로고    scopus 로고
    • Elevated venous glutamate levels in (pre)catabolic conditions result at least partly from a decreased glutamate transport activity
    • Hack V, Stütz O, Kinscherf R, Schykowski M, Kellerer M, Holm E, Droge W (1996) Elevated venous glutamate levels in (pre)catabolic conditions result at least partly from a decreased glutamate transport activity. J Mol Med 74:337-343
    • (1996) J Mol Med , vol.74 , pp. 337-343
    • Hack, V.1    Stütz, O.2    Kinscherf, R.3    Schykowski, M.4    Kellerer, M.5    Holm, E.6    Droge, W.7
  • 41
    • 0023488498 scopus 로고
    • Methods for the assessment of human body composition: Traditional and new
    • Lukaski HC (1987) Methods for the assessment of human body composition: traditional and new. Am J Clin Nutr 46:537-556
    • (1987) Am J Clin Nutr , vol.46 , pp. 537-556
    • Lukaski, H.C.1
  • 42
    • 0027396665 scopus 로고
    • Early changes of body composition in human immunodeficiency virus-infected patients: Tetrupolar body impedance analysis indicates significant malnutrition
    • Ott M, Lembcke B, Fischer H, Jager R, Polat H, Geier H, Rech M, Staszeswki S, Helm EB, Caspary W (1993) Early changes of body composition in human immunodeficiency virus-infected patients: tetrupolar body impedance analysis indicates significant malnutrition. Am J Clin Nutr 57:15-19
    • (1993) Am J Clin Nutr , vol.57 , pp. 15-19
    • Ott, M.1    Lembcke, B.2    Fischer, H.3    Jager, R.4    Polat, H.5    Geier, H.6    Rech, M.7    Staszeswki, S.8    Helm, E.B.9    Caspary, W.10
  • 45
    • 0022621388 scopus 로고
    • Arginine: Biochemistry, physiology and therapeutic implications
    • Barbul A (1986) Arginine: biochemistry, physiology and therapeutic implications. J Parent Ent Nutr 10:227-238
    • (1986) J Parent Ent Nutr , vol.10 , pp. 227-238
    • Barbul, A.1
  • 47
    • 0027467817 scopus 로고
    • Aging, training and exercise. A review of effects on plasma glutathione and lipid peroxides
    • Kretschmar M, Müller D (1993) Aging, training and exercise. A review of effects on plasma glutathione and lipid peroxides. Sports Med 15:196-209
    • (1993) Sports Med , vol.15 , pp. 196-209
    • Kretschmar, M.1    Müller, D.2
  • 48
    • 0022398710 scopus 로고
    • 3 , pH and the activity of carbonic anhydrase
    • 3 , pH and the activity of carbonic anhydrase. Eur J Biochem 152:381-386
    • (1985) Eur J Biochem , vol.152 , pp. 381-386
    • Häussinger, D.1    Gerok, W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.