Relative resistance of promastigotes of a virulent and an avirulent strain of Leishmania donovani to hydrogen peroxide

Free Radical Biology and Medicine

Volumn 21, Issue 5, 1996, Pages 683-689

  Goyal, Neena ^a   Roy, Uma ^a   Rastogi, Anil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Free radical; Hydrogen peroxide; Leishmania donovani; Promastigotes; Scavenging system

Indexed keywords

FREE RADICAL; HYDROGEN PEROXIDE; SCAVENGER; SUPEROXIDE;

ARTICLE; ENZYME ACTIVITY; LEISHMANIA DONOVANI; LEISHMANIASIS; PARASITE VIRULENCE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROMASTIGOTE; RESPIRATORY BURST; STRAIN DIFFERENCE;

LEISHMANIA DONOVANI;

EID: 0029761032     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/0891-5849(96)00130-X     Document Type: Article

References (24)

1. 1. Murray, H. W. Interaction of Leishmania with a macrophage cell line. Correlation between intracellular killing and generation of oxygen intermediates. J. Exp. Biol. 153:1690-1695; 1981.
2. 2. Pearson, R. D.; Harcus, J. L.; Symes, P. H.; Romito, R.; Donowitz, R. D. Failure of phagocytic oxidative response to protect human monocyte derived macrophages from infection by Leishmania donovani. J. Immunol 129:1282-1286; 1982.
3. 3. Murray, H. W. Cellular resistance to protozoal infection. Annu. Rev. Med. 37:61-69; 1986.
4. 4. Murray, H. W.; Cartelli, D. M. Killing of intracellular Leishmania donovani by human mononuclear phagocytes. J. Clin. Invest. 72:32-44; 1983.
5. 5. Murray, H. W. Susceptibility of Leishmania to oxygen intermediates and killing by normal macrophages. J. Exp. Med. 153:1302-1315; 1981.
6. 6. Reiner, N. E.; Kazura, J. W. Oxidant mediated damage of Leishmania donovani promastigotes. Infect. Immun. 36:1023-1027; 1982.
7. 7. Pearson, R. D.; Harcus, J. L.; Roberts, D.; Donowitz, G. R. Differential survial of Leishmania donovani amastigotes in human monocytes. J. Immunol. 131:1994-1999; 1983.
8. 8. Murray, H. W. Cell mediated immune response in experimental visceral leishmaniasis. II. Oxygen dependent killing of intracellular Leishmania donovani amastigotes. J. Immunol. 129:351-357; 1982.
9. 9. Channon, J. Y.; Blackwell, J. M. A study of the sensitivity of Leishmania donovani promastigotes and amastigotes to hydrogen peroxide 1. Differences in sensitivity correlates with parasite mediated removal of hydrogen peroxide.. Parasitology 91:197-206; 1985.
10. 2 scavenging. Parasitology 91:207-217; 1985.
11. 11. Zarley, J. H.; Britigan, B. E.; Wilson, M. E. Hydrogen peroxide mediated toxicity for Leishmania donovani chagasi promastigotes. Role of hydroxyl radical and protection by heat shock. J. Clin. Invest. 88:1511-1521; 1991.
12. 12. Novy, F. G.; Mac Neal, W. J. The cultivation of Trypanosoma brucei, a preliminary note. JAMA 41:1266-1268.
13. + in the in vitro morphogenic transformation of Leishmania donovani amastigotes to promastigotes. Proc. Indian Nat. Sci. Acad. B58:281-288; 1992.
14. 14. Sanyal, T.; Gangopadhyay, P.; Ghosh, D. K.; Sarkar, D. Expression of antigens in virulent and avirulent Indian strains of Leishmania donovani. J. Biosci. 19:291-299; 1994.
15. 15. Mukerjee, K.; Ghosh, D. K. Cytoplasmic and membrane antigens of Leishmania donovani. IRCS Med. Sci 11:785-786; 1983.
16. 16. Lillie, R. D. Strains and fluorochromes. In: Histopathologic techniques and practical histochemistry. New York: McGraw-Hill Book Company; 1965; 1965:107-141.
17. 17. Penketh, P. G.; Klein, R. A. Hydrogen peroxide metabolism in Trypanosoma brucei. Mol. Biochem. Parasit. 20:111-121; 1986.
18. 18. Homan-Muller, J. W.; Weening, R. S.; Roos, D. Production of hydrogen peroxide by phagocytizing human granulocytes. J. Lab. Clin. Med. 85:198-207; 1975.
19. 19. Leopold, F.; Wolfgang, A. G. Assays of glutathione peroxidase. In: Methods in enzymology. Vol. 105. New York: Academic Press; 1984:114-121.
20. 20. Racker, E. Glutathione reductase from Baker's Yeast Beef liver. J. Biol. Chem. 217:855-865; 1955.
21. 21. Aebi, H. Catalase in vitro. In: Methods in enzymology. Vol. 105. New York: Academic Press; 1984:121-126.
22. 22. Hissin, P. J.; Hilf, R. A. Fluorometeric method for determination of oxidized and reduced glutathione in tissues. Anal. Biochem. 74:214-226; 1976.
23. 23. Lowry, D. H.; Rosebrough, N. J.; Fair, A. L.; Randall, R. J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:265-276; 1951.
24. 24. Arrick, B. A.; Griffith, O. H.; Cerami, A. Inhibition of glutathione synthesis as a chemotherapeutic strategy for trypanosomiasis. J. Exp. Med. 153:720-725; 1981.