Alternative synthesis of duocarmycin SA using a tricyclic heteroaromatic intermediate prepared by palladium-catalyzed coupling reactions

Chemical and Pharmaceutical Bulletin

Volumn 44, Issue 8, 1996, Pages 1631-1633

  Muratake, Hideaki ^a   Tonegawa, Miyuki ^a   Natsume, Mitsutaka ^a  

^a Kawasaki   (Japan)

Author keywords

3H pyrrolo 3,2 f quinoline derivative; antitumor antibiotic; duocarmycin SA; formal synthesis; palladium catalyzed coupling

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DUOCARMYCIN A; DUOCARMYCIN B1; DUOCARMYCIN B2; DUOCARMYCIN SA; PALLADIUM; PYRINDAMYCIN A; PYRINDAMYCIN B; QUINOLINE DERIVATIVE; RACHELMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CANCER INHIBITION; CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; DRUG SYNTHESIS; STREPTOMYCES;

EID: 0029760961     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.44.1631     Document Type: Article

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28. Thanks are due to the Ministry of Education, Science, and Culture of Japan for financial support.