Changes in cerebral hemodynamics and oxygenation during hypothermic cardiopulmonary bypass in neonates and infants

Neonatology

Volumn 70, Issue 3, 1996, Pages 141-154

  Van Bel, Frank ^a   Zeeuwe, Petra E M ^a   Dorrepaal, Caroline A ^a   Benders, Manon J N L ^a   Van De Bor, Margot ^a   Hardjowijono, Rudy ^b  

^a Division of Neonatology   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cardiopulmonary bypass; Cerebral perfusion and metabolism; Infants

Indexed keywords

BRAIN ENZYME; CYTOCHROME C OXIDASE; HEMOGLOBIN; MITOCHONDRIAL ENZYME;

ARTERIAL OXYGEN TENSION; ARTICLE; BLOOD CARBON DIOXIDE TENSION; BLOOD PH; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; BRAIN CELL; BRAIN METABOLISM; BRAIN MITOCHONDRION; BRAIN PERFUSION; BRAIN TEMPERATURE; CARDIOPULMONARY BYPASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COOLING; ENERGY METABOLISM; HEART ARREST; HUMAN; INFANT; INFRARED SPECTROSCOPY; MEAN ARTERIAL PRESSURE; NEWBORN; OPEN HEART SURGERY; PRIORITY JOURNAL; REGRESSION ANALYSIS; WARMING;

BLOOD PRESSURE; BLOOD VOLUME; BRAIN; CARDIOPULMONARY BYPASS; ELECTRON TRANSPORT COMPLEX IV; HEMODYNAMIC PROCESSES; HEMOGLOBINS; HUMANS; HYPOTHERMIA, INDUCED; INFANT; INFANT, NEWBORN; OXIDATION-REDUCTION; OXYGEN; REGRESSION ANALYSIS;

EID: 0029760863     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000244359     Document Type: Article

References (38)

1. Lundar T, Lindberg H, Lindcgaard KF, Tjonneland S, Rian R, Bo G, Nomes H: Cerebral perfusion during major cardiac surgery in children, Pedialr Cardiol 1987;8:161-165.
2. Greeley WJ, Ungerleider RM, Kern FH, Brusino FG, Smith LR, Reves JG: Effects of cardiopulmonary bypass on cerebral blood flow in neonates, infants, and children, Circulation 1989;80(suppl I):209-215.
3. Greeley WJ, Kern FH, Ungerleider RM, Smith LR, Reves JG: The effect of hypothermic cardiopulmonary bypass and total circulatory arrest on cerebral metabolism in neonates, infants, and children, J Tho-rac Cardiovasc Surg 1991:101:783-794.
4. Buijs J, Van Bel F, Nandorf A, Hardjowijono R, Stijnen T, Otten-kamp J: Cerebral blood flow pattern and autoregulation during open-heart surgery in infants and young children: A transcranial, Doppler ultrasound study, Crit Care Med 1992;20:771-777.
5. Clarkson PM, McArthur A, MacAr-thur BA, Barrat-Boyes BG, Whitlock RM, Neutze JM: Developmental progress after cardiac surgery in infants using hypothermia and circulatory arrest, Circulation 1980:62:855-861.
6. Mujsce DJ, Towfighi J, Vannucci RC: Physiologic and neurologic aspects of hypothermic circulatory arrest in newborn dogs, Pediatr Res 1990;28:354-360.
7. Yager JY, Brucklachcr RM, Mujsce DJ, Vannucci RC: Cerebral oxidative metabolism during hypothermia and circulatory arrest in newborn dogs, Pediatr Res 1992:32: 547-552.
8. Greeley WJ, Bracey VA, Ungerlcid-er RM: Recovery' of cerebral metabolism and mitochondrial oxidation state is delayed after hypothermic circulatory arrest, Circulation 1991: 84(suppl III):400-406.
9. Jobsis FF: Noninvasive infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters, Science 1981:198: 1264-1267.
10. Edwards AD: Near infrared spectroscopy, Eur J Pediatr 1995; 154: S19-S21.
11. Colier WNJM, Vanhaaren NJCW, Oeseburg B: A comparative study of two near infrared spectrophotometers for the assessment of cerebral haemodynamics, Acta Anacsthesiol Scand 1995;39:101-105.
12. Van Bel F, Dorrepaai CA, Benders MJNL, Zeeuwe PEM, Van de Bor M, Berger HM: Changes in cerebral hemodynamics and oxygenation in the first 24 hours after birth asphyxia, Pediatrics 1993;92:365-372.
13. Kurth CD, Steven JM, Nicolson SC: Cerebral oxygenation during pediatric cardiac surgery using deep hypothermic circulatory arrest, Anesthesiology 1995:82:74-82.
14. Fallon P, Roberts I. Kirkhant FJ, Elliot MJ, Lloyd-Thomas A, Maynard R, Edwards AD: Cerebral hemodynamics during cardio-pulmo-nary by pass in children using near-infrared spectroscopy, Ann Thorac Surg 1993:56:1473-1477.
15. du Plessis AJ, Newburger J, Jonas RA, Hickey P, Naruse H, Tsuji M, Walsh A, Walter G, Wypij D, Volpe JJ: Cerebral oxygen supply and utilization during infant cardiac surgery, Ann Neurol 1995;37:488-497.
16. Ebert PA: Core cooling without adjuvants: in Moulton AL (ed): Congenital Heart Surgery': Current Techniques and Controversies, London, Butterworths, 1988. pp 180-185.
17. Wray S, Cope M, Delpy DT, Wyatt JS, Reynolds EOR: Characterisation of the near infrared absorption spectra of cytochrome aaj and haemoglobin for the non-invasivc monitoring of cerebral oxygenation, Bio-chim Biophys Acta 1988:993:84-192.
18. Delpy DT, Arridge S, Cope M, Edwards AD, Reynolds EOR, Richardson CE, Wray S, Wyatt J, Van Der Zee P: Quantitation of pathlength in optical spectroscopy, Adv Exp Med Biol 1989:247:41-46.
19. Wyatt JS, Edwards AD, Cope M, Delpy DT, McCormick DC, Potter A, Reynolds EOR: Response of cerebral blood volume to changes in arterial carbon dioxide tension in preterm and term infants, Pediatr Res 1991:29:553-557.
20. Brazy JE, Darrel VL, Mitnick MH, Jobsis FF: Noninvasivc monitoring of cerebral oxygenation in preterm infants: Preliminary observations, Pediatrics 1985;75:217-225.
21. Swan H: The importance of acid-base management for cardiac and cerebral preservation during open heart operations, Surg Gynecol Ob-stet 1984:158:391-414.
22. Glantz S, Slinker BK: Primer of Applied Regression and Analysis of Variance, New York, McGraw-Hill, 1990, pp 777-789.
23. Teitel DF, Klautz RJM, Steendijk P, Van Der Velde EM, Van Bel F, Baan J: The end-systolic prcssurc-volume relationship in the newborn lamb: Effects of loading and inotropic interventions, Pediatr Res 1991 ;29: 73-82.
24. Volpe JJ: Hypoxic-ischemic encephalopathy: Neuropathology and pathogenesis; in Volpe JJ (ed): Neurology of the Newborn, ed 3. Philadelphia, Saunders, 1995. pp 211-372.
25. Brun NC, Greisen G: Cerebrovascular responses to carbon dioxide as detected by near-infrared spectrophotometry: Comparison of three different measures, Pediatr Res 1994;36:20-24.
26. 33Xe clearance, Pediatr Res 1990;27:445-449.
27. Newburger JW, Jonas RA, Wer-novsky G: A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary' bypass in infant heart surgery, N Engl J Med 1993;329:1057-1064.
28. Murkin JM, Farrar JK, Tweed WA, McKenzie FH, Guiraudon G: Cerebral autoregulation and flow/metabolism coupling during cardiopulmonary bypass: The influence of PaCOy, Anesth Analg 1987:66:825-832.
29. Greeley WJ: The Effect of Deep Hypothermia and Circulatory Arrest on the Brain, Proc Syntp on Neuro-humoral Effects of Profound Hypothermia in Infant Heart Surgery, London, March 1993.
30. Swain JA, McDonald TJ Jr., Griffith PK, Balaban RS, Clark RE, Ceckler T: Low-flow hypothermic cardiopulmonary' bypass protects the brain, Thorac Cardiovasc Surg 1999 102: 76-83.
31. Burrows FA: Monitoring the adequacy of cerebral perfusion during cardiopulmonary' bypass in children using transcranial Doppler technology, J Neurosurg Anesthesiol 1993: 5:209-212.
32. Jobsis FF, Keizer JH, Manna JC: Reflectance spectrophotometry of cytochrome aay in vivo, J Appl Physiol 1977;43:858-872.
33. Thomiley MS, Wickramasinghe YABD, Rolfe P: Near infrared spectroscopy: A new technique for the non-invasivc monitoring of tissue and blood oxygenation in vivo, Bio-chem Soc Trans 1988:16:978-979.
34. Wickramasinghe YABD, Rolfe P, Palmer K, Spencer SA: Investigation of neonatal brain cytochrome redox by near infrared spectroscopy, Dev Brain Res 1995:89:307-308.
35. Astrup J: Energy-requiring cell functions in the ischemic brain, J Neurosurg 1982:56:482-497.
36. Tsuji M, Naruse H, Volpc JJ, Holtz-man D: Reduction of cytochrome aaj measured by near-infrared spectroscopy predicts cerebral energy loss in hypoxic piglets, Pediatr Res 1995;37:253-259.
37. Brown GC, Crompton M, Wray S: Cytochrome oxidase content of rat brain during development, Biochim Biophys Acta 1985;1057:273-275.
38. McCormick DC, Edwards AD, Brown JS, Wyatt JS, Potter A, Cope M, Delpy DT, Reynolds EOR: Effect of indomethacin on cerebral oxidized cytochrome oxidase in preterm infants, Pediatr Res 1993:33: 603-608.