Great lakes forensic toxicology and the implications for research and regulatory programs

Toxicology and Industrial Health

Volumn 12, Issue 4, 1996, Pages 563-571

  Gilbertson, Michael ^a  

^a International Joint Commission   (Canada)

Author keywords

causality; epidemiological criteria; health; injury; regulatory; zero discharge

Indexed keywords

ARTICLE; MEDICAL RESEARCH; TOXICOLOGY; WATER CONTAMINATION; WATER QUALITY;

ANIMALS; COHORT STUDIES; CONSERVATION OF NATURAL RESOURCES; DATA COLLECTION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; FISH PRODUCTS; FOOD CONTAMINATION; FOOD POISONING; FORENSIC MEDICINE; GREAT LAKES REGION; HUMANS; REPRODUCTION; WATER POLLUTANTS, CHEMICAL;

EID: 0029760182     PISSN: 07482337     EISSN: None     Source Type: Journal    
DOI: 10.1177/074823379601200328     Document Type: Article

References (28)

1. Baumann, P., Smith, I., and Metcalfe, C. (1996). “Linkages between chemical contaminants and tumors in benthic Great Lakes fish.” J. Great Lakes Res. 22:131-152.
2. Beland, P., Deguise, S., Girard, C., Lagace, A., Martineau, D., Michaud, R., Muir, D.C.G., Norstrom, R.J., PELLETIER, E., RAY, S., and SHUGART, L.R. (1993). “Toxic compounds and reproductive effects in St. Lawrence beluga whales.” J. Great Lakes Res. 19:766-775.
3. Bishop, C.A., Brooks, R.J., CAREY, J.H., NG, P., NORSTROM, R.J., and LEAN, D.R.S. (1991). “The case for a cause-effect linkage between environmental contamination and development in eggs of the common snapping turtle (Chelydra s. serpentina) from Ontario, Canada.” J. Toxicol. Environ. Health 33:521-548.
4. Colburn, T. (1991). “Epidemiology of Great Lakes bald eagles.” J. Toxicol. Environ. Health 33:395-454.
5. Colburn, T. and Clement, C. (eds.) (1992). Chemically-Induced Alterations in Sexual and Functional Development: The Wildlife/Human Connection. Advances in Modem Environmental Toxicology, vol. 21. Princeton Scientific Publishing, Co., Inc. Princeton, NJ.
6. Daly, H.B. (1993). “Laboratory rat experiments show consumption of Lake Ontario salmon causes behavioral changes: support for wildlife and human research results.” J. Great Lakes Res. 19:784-788.
7. Fox, G.A. (1991). “Practical causal inference for ecoepidemiologists. “ J. Toxicol. Environ. Health 33:359-373.
8. Fox, G.A. (1993). “What have biomarkers told us about the effects of contaminants on the health of fish-eating birds in the Great Lakes? The theory and a literature review.” J. Great Lakes Res. 19:722-736.
9. Gilbertson, M. (1988). “Epidemics in birds and mammals caused by chemicals in the Great Lakes.” In: Toxic Contaminants and Ecosystem Health: A Great Lakes Focus (M.S. Evans, ed.). John Wiley & Sons, Inc., NY. pp. 133–152.
10. Gilbertson, M. and Schneider, R.S. (1991). “International Joint Commission Workshop on Cause-Effect Linkages: Preface.” J. Toxicol. Environ. Health 33(4):v-x.
11. Gilbertson, M. and Schneider, R.S. (1993). “Causality: The missing link between science and policy.” J. Great Lakes Res. 19:720-721.
12. Gilbertson, M., Kubiak, T.J., Ludwig, J.P., and Fox, G.A. (1991). “Great Lakes embryo mortality, edema, and deformities syndrome (GLEMEDS) in colonial fish-eating birds: Similarity to chick-edema disease.” J. Toxicol. Environ. Health 33:455-520.
13. Grasman, K.A., SCANLON, P.F., FOX, G.A., and LUDWIG, J.P. (1996). “Organochlorine-associated immunosuppression in prefledging Caspian terns and herring gulls from the Great Lakes: An epidemiological study.” Environ. Health Perspect. 104(Suppl.4)
14. Great Lakes Water Quality Board (1993). Proceedings of a Workshop on Legislative and Regulatory Considerations for Virtual Elimination of Persistent Toxic Substances. International Joint Commission, Windsor, Ontario.
15. Jacobson, J.L. and Jacobson, S.W. (1993). “A four-year follow up study of children born to consumers of Lake Michigan fish.” J. Great Lakes Res. 19:776-783.
16. Jacobson, J.L., Fein, G.G., Jacobson, S.W., Schwartz, P.M., and Dowler, J.K. (1985). “The effect of intrauterine PCB exposure on visual recognition memory.” Child Develop. 56:853-860.
17. Kuhn, T.S. (1962). The Structure of Scientific Revolutions. University of Chicago Press. Chicago, IL.
18. Leatherland, J.F. (1993). “Field observations on reproductive and developmental dysfunction in introduced and native salmonids from the Great Lakes.” J. Great Lakes Res. 19:737-751.
19. Lonky, E., Reihman, J., Darvill, T., Mather, J., SR., and Daly, H. (1996). “Neonatal behavioral assessment scale performance in humans influenced by maternal consumption of environmentally contaminated Lake Ontario fish.” J. Great Lakes Res. 22:198-212.
20. Ludwig, J.P., Giesy, J.P., Summer, C.L., Bowerman, W., Heaton, S., Aulerich, R., Bursian, S., Auman, H.J., Jones, P.D., Williams, L.L., Tillitt, D.E., and Gilbertson, M. (1993). “A comparison of water quality criteria for the Great Lakes based on human and wildlife health.” J. Great Lakes Res. 19:789-807.
21. Ludwig, J.P., Kurita-Matsuba, H., Auman, H.J., Ludwig, M.E., Summer, C.L., Giesy, J.P., Tillitt, D.E., and Jones, P.D. (1996). “Deformities, PCBs and TCDD-equivalents in double-crested cormorants (Phalacrocora x auritus) and Caspian terns (Hydroprogne caspia) of the upper Great Lakes 1986-1991: Testing a cause-effect hypothesis.” J. Great Lakes Res. 22:172-197.
22. Mac, M.J. and Edsall, C.C. (1991). “Environmental contaminants and the reproductive success of lake trout in the Great Lakes: An epidemiological approach.” J. Toxicol. Environ. Health 33:375-394.
23. Mac, M.J., Schwartz, T.R., Edsall, C.C., and Frank, A.M. (1993). “Polychlorinated biphenyls in Great Lakes lake trout and their eggs: Relations to survival and congener composition 1979-1988. “ J. Great Lakes Res. 19:752-765.
24. McMaster, M.E., Van Der Kraak, G.J., and Munkittrick, K.R. (1996). “An epidemiological evaluation of the biochemical basis for steroid hormonal depression in fish exposed to industrial wastes.” J. Great Lakes Res. 22:153-171.
25. Peterson, R.E. and Cook, P.M. (1993). “An assessment of the contribution of contamination of lake trout eggs by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related chemicals to lake trout recruitment failure in Lake Ontario.” In: Report from Uppsala Workshop on Reproductive Disturbances in Fish (N. Leiss, ed.). Report 4346. Swedish Environmental Protection Agency, Solna, Sweden. pp.71–73.
26. Swain, W.R. (1991). “Effects of organochlorine chemicals on the reproductive outcome of humans who consumed contaminated Great Lakes fish: an epidemiologic consideration.” J. Toxicol. Environ. Health 33:587-639.
27. U.S. Department Of Health, Education And Welfare (1964). Smoking and Health. Report of the Advisory Committee to the Surgeon General. Public Health Service Publication 1103. Washington, DC.
28. Wren, C.D. (1991). “Cause-effect linkages between chemicals and populations of mink (Mustela vison) and otter (Lutra canadensis) in the Great Lakes basin. “ J. Toxicol. Environ. Health 33:549-586.