Xenoimplantation using a diffusion chamber with a B-cell line (MIN6) as a bioartificial endocrine pancreas (Bio-AEP)

Cell Transplantation

Volumn 5, Issue 5 SUPPL. 1, 1996, Pages

  Ohgawara, Hisako ^a,c   Miyazaki, Jun Ichi ^a   Nakagawa, Yoshihiko ^a   Sato, Sumihiko ^a   Karibe, Sachiyo ^a   Akaike, Toshihiro ^b  

^a TOHOKU UNIVERSITY   (Japan)

^b Tokyo Institute of Technology   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Bioartificial endocrine pancreas (Bio AEP); Diffusion chamber; Transgenic mouse insulinoma cells (MIN6); Xenograft implantation

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ARTICLE; ARTIFICIAL PANCREAS; GLUCOSE BLOOD LEVEL; INSULINOMA; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES; TRANSGENIC MOUSE;

ANIMALIA; MUS MUSCULUS; PHOCIDAE;

EID: 0029759982     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1016/0963-6897(96)00044-9     Document Type: Article

References (5)

1. Ishihara, H.; Asano, T.; Tsukada, K.; Katagiri, H.; Inukai, M.; Anai, M.; Kikuchi, M.; Yazaki, Y.; Miyazaki, J.; Oka, Y. Pancreatic beta cell line MIN6 exhibit characteristics of glucose metabolism and glucose-stimulated insulin secretion similar to those of normal islets. Diabetologia 36:1139-1145; 1993.
2. Ohgawara, H.; Nishijima, S.; Satoh, A.; Mochizuki, N.; Hirata, Y. New type of bioartificial pancreas employing a diffusion chamber. In: Ota, K., Agishi, T., eds. Artificial organs. Vol. 14, Suppl. 3. ISAO Press; Cleveland: 1990:11.
3. Ohgawara, H.; Kobayashi, A.; Kawamura, M.; Karibe, S.; Omori, Y.; Ajaile, T. Development of a method for embedded-culture of pig pancreatic islet-like cell clusters in agarose containing maltose-carrying polystyrene (HEMA) and nicotinamide. Cell Transplant. 3:83-89; 1994.
4. Ohgawara, H.; Miyazaki, J.; Karibe, S.; Tashiro, F.; Akaike, T.; Hashimoto, Y. Embedded-culture of pancreatic B-cells derived from transgenic mouse insulinoma as a potential source for xenotransplantation using a diffusion chamber. Cell Transplant. (in press)
5. Sakurada, M.; Kanatsuka, A.; Saitoh, T.; Makino, H.; Yamamura, K.; Miyazaki, J.; Kikuchi, M.; Yoshida, S. Relation between glucose-stimulated insulin secretion and intracellular calcium accumulation studied with a superfusion system of a glucose-responsive pancreati B-cell line MIN6. Endocrinology 132:2659-2665; 1993.