Prognostic factors in gastric cancer: The value of vascular invasion, mitotic rate and lymphoplasmacytic infiltration

British Journal of Cancer

Volumn 74, Issue 5, 1996, Pages 766-772

  Setala L P ^a   Kosma, V M ^a,b   Marin, S ^a   Lipponen, P K ^b   Eskelinen, M J ^a   Syrjanen K J ^a,b   Alhava, E M ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Gastric cancer; Histology; Lauren classification; Mitotic index; Prognosis; TNM classification

Indexed keywords

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER INVASION; CANCER SURVIVAL; CARDIOVASCULAR SYSTEM; CELL INFILTRATION; FEMALE; HUMAN; HUMAN TISSUE; LYMPHATIC SYSTEM; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; MALE; MITOSIS RATE; MULTIVARIATE ANALYSIS; PLASMA CELL; PRIORITY JOURNAL; STOMACH CANCER; STOMACH WALL; SURVIVAL TIME; TUMOR DIFFERENTIATION; TUMOR LOCALIZATION; TUMOR VOLUME;

EID: 0029759855     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.434     Document Type: Article

References (31)

1. AALTOMAA S, LIPPONEN P, ESKELINEN M, KOSMA VM, MARIN S, ALHAVA E AND SYRJÄNEN K. (1992). Mitotic indexes as prognostic predictors in female breast cancer. J. Cancer Res. Clin. Oncol., 118, 75-81.
2. BONENKAMP JJ, SONGUN I, HERMANS J, SASAKO M, WELVAART K, PLUKKER JTM, VAN ELK P, OBERTOP H, GOUMA DJ, TAAT CW, VAN LANSCHOT J, MEYER S, DE GRAAF PW, VON MEYENFELDT MF, TILANUS H AND VAN DE VELDE CJH. (1995). Randomised comparison of morbidity after D1 and D2 dissection for gastric cancer in 996 Dutch patients. Lancet, 345, 745 748.
3. CONCETTI HF, KATO Y, SUGANO H AND KITAGAWA T. (1981). Natural history of gastric cancer with special reference to the 'early cancer' stage: a mitotic index study on original and recurrent carcinomas. Gann, 72, 665 672.
4. CROSS RD, START RD AND SMITH JHF. (1990). Does delay in fixation affect the number of mitotic figures in processed tissues? J. Clin. Pathol., 43, 597-599.
5. DAVESSAR K, PEZZULLO JC, KESSIMIAN N, HALE JH AND JAUREGUI HO. (1990). Gastric adenocarcinoma: prognostic significance of several pathologic parameters and histological classifications. Hum. Pathol., 21, 325-332.
6. DOUGLASS HO Jr. (1994). Adjuvant therapy of gastric cancer: have we made any progress? Ann. Oncol., 5, S49-57.
7. GABBERT HE, MEIER S, GERHARZ CD AND HOMMEL G. (1991). Incidence and prognostic significance of vascular invasion in 529 gastric cancer patients. Int. J. Cancer, 49, 203-207.
8. HAAPASALO H, PESONEN E AND COLLAN Y. (1989). Volume-corrected mitotic index (M/V-index). The standard of mitotic activity in neoplasms. Path. Res. Pract., 185, 551-554.
9. HAUGSTVEDT TK, VISTE A, EIDE GE, SÖREIDE O AND MEMBERS OF THE NORWEGIAN STOMACH CANCER TRIAL. (1993). Norwegian mutlicentre study of survival and prognostic factors in patients undergoing curative resection for gastric carcinoma. Br. J. Surg., 80, 475-478.
10. HERMANEK P. (1986). Prognostic factors in stomach cancer surgery. Eur. J. Surg. Oncol., 12, 241-246.
11. HERMANEK P AND WITTEKIND C. (1995). News of TNM and its use for classification of gastric cancer. World J. Surg., 19, 491 495.
12. HERMANS J, BONENKAMP JJ, BOON MC, BUNT AMG, OHUYAMA S, SASAKO M AND VAN DE VELDE CJH. (1993). Adjuvant therapy after curative resection for gastric cancer: meta-analysis of randomized trials. J. Clin. Oncol., 11, 1441-1447.
13. IRIYAMA K, MIKI C, ILUNGA K, OSAWA T, TSUCHIBASHI T AND SUZUKI H. (1993). Prognostic significance of histological type in gastric carcinoma with invasion confined to the stomach wall. Br. J. Surg., 80, 890-892.
14. KORENAGA D, SAITO A, BABA H, WATANABE A, OKAMURA T, MAEHARA Y AND SUGIMACHI K. (1990). Cytomorphometrically determined DNA-content, mitotic activity, and lymph node metastasis in clinical gastric cancer. Surgery, 107, 262-267.
15. KORENAGA D, IKEDA T, MAEHARA Y AND SUGIMACHI K. (1995). Cytophotometrically determined DNA-content, mitotic index and proliferative activity in clinical gastric cancer (abstract in English). Gan-To-Kagaku-Ryoho, 22, S168-171.
16. LAURÉN P. (1965). The two histological main types of gastric carcinoma: diffuse and so-called intestinal type carcinoma. An attempt at a histo-clinical classification. Acta Pathol. Microbiol. Scand., 64, 31-49.
17. LIPPONEN PK, KOSMA V-M, COLLAN Y, KULJU T, KOSUNEN O AND ESKELINEN M. (1990). Potential of nuclear morphometry and volume-corrected mitotic index in grading transitional cell carcinoma of the urinary bladder. Eur. Urol., 17, 333-337.
18. LIPPONEN PK, ESKELINEN MJ, JAUHIAINEN K, HARJU E AND TERHO R. (1993). Tumour infiltrating lymphocytes as an independent prognostic factor in transitional cell bladder cancer. Eur. J. Cancer, 29A, 69-75.
19. LISBORG P, JATZKO G, HORN M, NEUMANN HJ, MÜLLER M, STETTNER H AND DENK H. (1994). Radical surgery (R2 resection) for gastric cancer. A multivariate analysis. Scand. J. Gastroenterol., 29, 1024-1028.
20. MARUYAMA K. (1987). The most important prognostic factors for gastric cancer patients. A study using univariate and multivariate analysis. Scand. J. Gastroenterol., 22, S63 68.
21. MORI M, ADACHI Y, KAMAKURA T, IKEDA Y, MAEHARA Y AND SUGIMACHI K. (1995). Neural invasion in gastric carcinoma. J. Clin. Pathol., 48, 136-142.
22. NOGUCHI Y. (1990). Blood vessel invasion in gastric carcinoma. Surgery, 107, 140-148.
23. NOGUCHI Y, IMADA T, MATSUMOTO A, COIT DG AND BRENNAN MF. (1989). Radical surgery for gastric cancer. A review of the Japanese experience. Cancer, 64, 2053 2062.
24. OKADA M, KOJIMA S, MURAKAMI M, FUCHIGAMI T, TSUNEYOSHI Y, OMAET AND IWASHITA A. (1983). Human gastric carcinoma:prognosis in relation to macroscopic and microscopic features of the primary tumour. J. Natl Cancer. Inst., 71, 275-279
25. PAILE A. (1971). Morphology and prognosis of carcinoma of the stomach. Ann. Chir. Gynaecol., 60, S34-47.
26. SCHMITZ-MOORMAN P, HERMANEK P AND HIMMELMANN GW. (1992). Morphological predictors of survival in early and advanced gastric carcinoma. J. Cancer Res. Clin. Oncol., 118, 296-302.
27. SIEWERT JR, BÖTTCHER K, RODER JD, BUSCH R, HERMANEK P, MEYER HJ AND THE GERMAN GASTRIC CARCINOMA STUDY GROUP. (1993). Prognostic relevance of systematic lymph node dissection in gastric carcinoma. Br. J. Surg., 80, 1015 1018.
28. TABUCHI Y, TAKIGUCHI Y, NAKAMURA T, NAKAE S, IMANISHI K, MURAYAMA Y AND SAITOH Y. (1986). Mitotic activity of cancer cells and survival of gastric cancer patients. (abstract in English). Nippon Geka Gakkai Zasshi - J. Jpn. Surg. Soc., 87, 44 48.
29. TANAKA A, WATANABE T, OKUNO K AND YASUTOMI M. (1994). Perineural invasion as a predictor of recurrence of gastric cancer. Cancer, 73, 550 555.
30. VESALAINEN S, LIPPONEN P, TALJA M AND SYRJÄNEN K. (1995). Mitotic activity and prognosis in prostatic adenocarcinoma. The Prostate, 26, 80-86.
31. YU CC-W, LEVISON DA, DUNN JA, WARD LC, DEMONAKOU M, ALLUM WH AND HALLISEY MT. (1995). Pathological prognostic factors in the second British Stomach Cancer Group trial of adjuvant therapy in resectable gastric cancer. Br. J. Cancer, 71, 1106-1110.