Effect of interferon α on HLA-DR expression by human buccal epithelial cells

Archivum Immunologiae et Therapiae Experimentalis

Volumn 44, Issue 2-3, 1996, Pages 83-88

  Smith, J Kelly ^a   Chi, David S ^a   Krishnaswamy, Guha ^a   Srikanth, Sujata ^a   Reynolds, Scott ^a   Berk, Steven L ^a  

^a East Tennessee State University   (United States)

Author keywords

cytokine mRNA transcripts; human buccal epithelial cells; human lymphoblastoid interferon; MHC class II antigens; mucosal associated mononuclear cells

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8;

ARTICLE; CHEEK MUCOSA; EPITHELIUM CELL; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; POLYMERASE CHAIN REACTION;

CELLS, CULTURED; CHEEK; EPITHELIUM; HLA-DR ANTIGENS; HUMANS; INTERFERON TYPE II; MOUTH MUCOSA;

EID: 0029759580     PISSN: 0004069X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. BABIUCH L., MIAN M., KAMIŃSKA E., SZYMAŃSKA B. and GEORGIADES J. A. (1993): An interim report on the effect of natural human Interferon alpha (IFN-α) lozenges in patients seropositive for the human immunodeficiency virus type 1 (HIV-1). Arch. Immunol. Ther. Exp., 41, 213-219.
2. CABAN J., MOSSOR-OSTROWSKA J., ŻYRKOWSKA-BIEDA T., ZEJC M., JANAS-SKULINA U., CIEŚLA A., CUMMINS J. M. and GEORGIADES J. A. (1993): Treatment of chronic viral hepatitis type B with oral mucosal administration of natural human interferon alpha lozenges. Arch. Immunol. Ther. Exp., 41, 229-235.
3. CUMMINS J. M., HUTCHESON D. P., CUMMINS M. J., GEORGIADES J. A. and RICHARDS A. B. (1993): Oral therapy with human interferon alpha in calves experimentally injected with infectious bovine rhinotracheitis virus. Arch. Immunol. Ther. Exp., 41, 193-197.
4. DAWSON M. M. (1991): Interferon gamma. In DAWSON M. M.: Lymphokines and interleukins. CRC Press, Boca Raton, Florida, 190-209.
5. GEORGIADES J. A. (1996): Natural human interferon α may act differently when given parenterally or orally to patients chronically infected with hepatitis B virus. Arch. Immunol. Ther. Exp., 44, 11-22.
6. GUTTERMAN J. U. (1994): Cytokine therapeutics: lessons from interferon α. Proc. Natl. Acad. Sci. USA, 91, 1198-1205.
7. HULTON M., LEVIN D. and FREEDMAN L. (1992): Randomized, placebo-controlled, double-blind study of low dose oral interferon-α in HIV-1 antibody positive patients. J. AIDS, 5, 1084-1090.
8. KAISER G., JAEGER H., BIRKMAN J., POPPINGER J., CUMMINS J. and GALLMEIER W. (1992): Low-dose oral natural interferon-α in 29 patients with HIV-1 infection: a double-blind, randomized, placebo-controlled trial. AIDS, 6, 563-569.
9. LECCE J. G., CUMMINS J. M. and RICHARDS A. B. (1990): Treatment of rotavirus infection in newborn pigs using natural human interferon alpha. Mol. Biother., 2, 211-216.
10. PARRONCHI P., DE CARTI M., MANETTI R., SIMONELLI C., SAMPOGNARO S., PICCINNI M.-P., MACCHIA D., MAGGI E., DEL PRETE G. and ROMAGNANI S. (1992): IL-4 and IFN (α and γ) exert opposite regulatory effects on the development of cytotoxic potential by Th1 or Th2 human T cell clones. J. Immunol., 149, 2977-2983.
11. H2 responses: a key role for the "natural" immune response? Immunol. Today, 13, 379-381.
12. ROOK G. (1993): Immunity to viruses, bacteria and fungi. In ROITT I. M., BROSTOFF J. and MALE D. K. (eds.): Immunology. 3rd ed. J. B. Lippincott Co., Philadelphia, 16.5-16.6.
13. SCHAFER T. W., LEEBERMAN M., COHEN M. and CANE P. (1972): Interferon administration orally: protection of neonatal mice from lethal virus challenge. Science, 176, 1326-1327.
14. SRIKANTH S., SMITH J. K., CHI D. S., REYNOLDS B. S. and KRISHNASWAMY G. (1995): In vitro immunomodulatory effects of interferon alpha on T cell responses: implications for the atopic state. Abstract. J. Allergy Clin. Immunol., 94, 363.
15. WEISS R. C., CUMMINS J. M. and RICHARDS A. B. (1991): Low dose orally administered alpha interferon treatment for feline leukemia virus infection. J. Am. Vet. Med. Assoc., 199, 1477-1481.
16. ZIELIŃSKA W., PASZKIEWICZ J., KORCZAK A., WLASIUK M., ŻÓŁTOWSKA A., SZUTOWICZ A., CUMMINS J. M. and GEORGIADES J. A. (1993): Treatment of fourteen chronic active HBsAg+, HBeAg+ hepatitis patients with low dose natural human interferon alpha administered orally. Arch. Immunol. Ther. Exp., 41, 241-251.