-
2
-
-
0000298187
-
Creatine phosphokinase and cardiotoxicity in adriamycin chemotherapy and its modification by WR-1065
-
Bhanumathi P, Salesh EB, Vasudevan DM. Creatine phosphokinase and cardiotoxicity in adriamycin chemotherapy and its modification by WR-1065. Biochem Arch 1992;8:335-8
-
(1992)
Biochem Arch
, vol.8
, pp. 335-338
-
-
Bhanumathi, P.1
Salesh, E.B.2
Vasudevan, D.M.3
-
3
-
-
0006496046
-
Randomized trial of carboplatin (CBDCA) vs CBDCA + amifostine in advanced malignancy
-
Budd GT, Bukowski RM, Murthy S et al. Randomized trial of carboplatin (CBDCA) vs CBDCA + amifostine in advanced malignancy. Proc Am Soc Clin Oncol 1994;13:442
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 442
-
-
Budd, G.T.1
Bukowski, R.M.2
Murthy, S.3
-
4
-
-
0022504243
-
Protection by WR-2721 of human bone marrow function following irradiation
-
Constine LS, Zagars G, Rubin P et al. Protection by WR-2721 of human bone marrow function following irradiation. Int J Radiat Oncol Biol Phys 1986;12:1505-8
-
(1986)
Int J Radiat Oncol Biol Phys
, vol.12
, pp. 1505-1508
-
-
Constine, L.S.1
Zagars, G.2
Rubin, P.3
-
5
-
-
0023707614
-
In vitro rat myocyte cardiotoxicity model for antitumor antibiotics using adenosine triphosphate/protein ratios
-
Dorr RT, Bozak KA, Shipp NG, Hendrix M, Alberts DS, Ahmann F. In vitro rat myocyte cardiotoxicity model for antitumor antibiotics using adenosine triphosphate/protein ratios. Cancer Res 1988;48:5222-7
-
(1988)
Cancer Res
, vol.48
, pp. 5222-5227
-
-
Dorr, R.T.1
Bozak, K.A.2
Shipp, N.G.3
Hendrix, M.4
Alberts, D.S.5
Ahmann, F.6
-
6
-
-
0000170555
-
Anthracycline cardioprotection by amifostine (WR-2721) and its active metabolite (WR-1065) in vitro
-
Abstract 1495
-
Dorr RT, Lagel KE. Anthracycline cardioprotection by amifostine (WR-2721) and its active metabolite (WR-1065) in vitro [Abstract 1495]. Proc Am Soc Clin Oncol 1994;13:435
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 435
-
-
Dorr, R.T.1
Lagel, K.E.2
-
7
-
-
9544220859
-
In vitro treatment of leukemic bone marrow for autologous transplantation
-
Douay L, Gorin NC, Gerota I, Najman A, Duhamel G. In vitro treatment of leukemic bone marrow for autologous transplantation. Exp Hematol 1982;10(suppl 12):113
-
(1982)
Exp Hematol
, vol.10
, Issue.12 SUPPL.
, pp. 113
-
-
Douay, L.1
Gorin, N.C.2
Gerota, I.3
Najman, A.4
Duhamel, G.5
-
8
-
-
0028028434
-
Comparative effects of amifostine (Ethyol) on normal hematopoietic stem cells versus human leukemic cells during ex vivo purging in autologous bone marrow transplants
-
Douay L, Hu C, Giarratana MC, Gorin NC. Comparative effects of amifostine (Ethyol) on normal hematopoietic stem cells versus human leukemic cells during ex vivo purging in autologous bone marrow transplants. Semin Oncol 1994;21(suppl 11):16-20
-
(1994)
Semin Oncol
, vol.21
, Issue.11 SUPPL.
, pp. 16-20
-
-
Douay, L.1
Hu, C.2
Giarratana, M.C.3
Gorin, N.C.4
-
9
-
-
0023255554
-
Differences in kinetics of hematopoietic reconstitution between ALL and ANLL after autologous bone marrow transplantation with marrow treated in vitro with mafosfamide (ASTA-Z 7557)
-
Douay L, Laporte JP, Mary JY. Differences in kinetics of hematopoietic reconstitution between ALL and ANLL after autologous bone marrow transplantation with marrow treated in vitro with mafosfamide (ASTA-Z 7557). Bone Marrow Transplant 1987;2:33-43
-
(1987)
Bone Marrow Transplant
, vol.2
, pp. 33-43
-
-
Douay, L.1
Laporte, J.P.2
Mary, J.Y.3
-
10
-
-
0028893813
-
Randomized placebo controlled multicenter evaluation of diethyldithiocarbamate for chemoprotection against cisplatin induced toxicities
-
Gandara DR, Nahhas WA, Adelson MD et al. Randomized placebo controlled multicenter evaluation of diethyldithiocarbamate for chemoprotection against cisplatin induced toxicities. J Clin Oncol 1995;13:490-6
-
(1995)
J Clin Oncol
, vol.13
, pp. 490-496
-
-
Gandara, D.R.1
Nahhas, W.A.2
Adelson, M.D.3
-
11
-
-
0023258489
-
WR-2721 and high-dose cisplatin: An active combination in the treatment of metastatic melanoma
-
Glover D, Glick J, Weiler C, Fox K, Guerry D. WR-2721 and high-dose cisplatin: an active combination in the treatment of metastatic melanoma. J Clin Oncol 1987,5:574-8
-
(1987)
J Clin Oncol
, vol.5
, pp. 574-578
-
-
Glover, D.1
Glick, J.2
Weiler, C.3
Fox, K.4
Guerry, D.5
-
12
-
-
0022521737
-
Autologous bone marrow transplantation using marrow incubated with ASTA Z 7557 in adult acute leukemia
-
Gorin NC, Douay L, Laporte JP et al. Autologous bone marrow transplantation using marrow incubated with ASTA Z 7557 in adult acute leukemia. Blood 1986;67:1367-76
-
(1986)
Blood
, vol.67
, pp. 1367-1376
-
-
Gorin, N.C.1
Douay, L.2
Laporte, J.P.3
-
13
-
-
0006963475
-
WR-2721 chemoprotection of doxorubicin toxicity in mice
-
Green D, Wright A, Schein P, Clarke R, Lombardi VT. WR-2721 chemoprotection of doxorubicin toxicity in mice. Proc Am Assoc Cancer Res 1992;33:490
-
(1992)
Proc Am Assoc Cancer Res
, vol.33
, pp. 490
-
-
Green, D.1
Wright, A.2
Schein, P.3
Clarke, R.4
Lombardi, V.T.5
-
14
-
-
0026521506
-
Interim analysis of a randomized trial of radiation therapy of rectal cancer with/without WR-2721
-
Kligerman MM, Liu TF, Liu Y et al. Interim analysis of a randomized trial of radiation therapy of rectal cancer with/without WR-2721. Int J Radiat Oncol Biol Phys 1992;22:799-802
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.22
, pp. 799-802
-
-
Kligerman, M.M.1
Liu, T.F.2
Liu, Y.3
-
15
-
-
0023681297
-
Final report of phase I trial of WR-2721 before protracted fractionated radiation therapy
-
Kligerman MM, Turrist AT, Urtasun RC et al. Final report of phase I trial of WR-2721 before protracted fractionated radiation therapy. Int J Radiat Oncol Biol Phys 1988;14:1119-22
-
(1988)
Int J Radiat Oncol Biol Phys
, vol.14
, pp. 1119-1122
-
-
Kligerman, M.M.1
Turrist, A.T.2
Urtasun, R.C.3
-
16
-
-
0343255189
-
Influence of amifostine (AMI) on the pharmacokinetics (PK) of carboplatin (CARBO) in patients with solid tumors
-
Korst AEC, Gall HE, Vermorken JB, Fichtinger-Schepman AMJ, Van der Vijgh WJF. Influence of amifostine (AMI) on the pharmacokinetics (PK) of carboplatin (CARBO) in patients with solid tumors. Proc Am Soc Clin Oncol 1995;14:172
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
, pp. 172
-
-
Korst, A.E.C.1
Gall, H.E.2
Vermorken, J.B.3
Fichtinger-Schepman, A.M.J.4
Van Der Vijgh, W.J.F.5
-
17
-
-
9544246020
-
Influence of amifostine on the ami tumor activity, pharmacokinetics and pharmacodynamics of carboplatin in nude mice
-
Abstract 071.
-
Korst AEC, Van der Vijgh WJF, Van de Sterre MLT, Fichtinger-Schepman AMJ, Vermorken JB, Boven E. Influence of amifostine on the ami tumor activity, pharmacokinetics and pharmacodynamics of carboplatin in nude mice [Abstract 071]. Proceedings of the 7th International Symposium on platinum and other metal coordination compounds in cancer chemotherapy, 1995
-
(1995)
Proceedings of the 7th International Symposium on Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy
-
-
Korst, A.E.C.1
Van Der Vijgh, W.J.F.2
Van De Sterre, M.L.T.3
Fichtinger-Schepman, A.M.J.4
Vermorken, J.B.5
Boven, E.6
-
18
-
-
0345032784
-
Amifostine is a novel stimulant of bone marrow progenitor growth in myelodysplastic syndromes
-
Abstract 1327
-
List AF, Heaton R, Glinsmann-Gibson B, Capizzi RL. Amifostine is a novel stimulant of bone marrow progenitor growth in myelodysplastic syndromes [Abstract 1327]. Blood 1995;86(suppl 1):335a
-
(1995)
Blood
, vol.86
, Issue.1 SUPPL.
-
-
List, A.F.1
Heaton, R.2
Glinsmann-Gibson, B.3
Capizzi, R.L.4
-
19
-
-
8944246555
-
Pharmacokinetic-dynamic relationship of weekly high dose cisplatin (C) in solid tumor patients (PTS)
-
Ma J, Verweij J, Planting AST, de Boer-Dennert M, Van der Burg MEL, Stoter G, Schellens JHM. Pharmacokinetic-dynamic relationship of weekly high dose cisplatin (C) in solid tumor patients (PTS) [Abstract]. Proc Am Soc Clin Oncol 1994;13:133
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
, pp. 133
-
-
Ma, J.1
Verweij, J.2
Planting, A.S.T.3
De Boer-Dennert, M.4
Van Der Burg, M.E.L.5
Stoter, G.6
Schellens, J.H.M.7
-
20
-
-
0025856595
-
New protective agents for bone marrow in cancer therapy
-
McColloch W, Scheffer BJ, Schein PS. New protective agents for bone marrow in cancer therapy. Cancer Invest 1991;9:279-87
-
(1991)
Cancer Invest
, vol.9
, pp. 279-287
-
-
McColloch, W.1
Scheffer, B.J.2
Schein, P.S.3
-
21
-
-
0028069933
-
Preliminary results of a pilot study using WR-2721 before fractionated irradiation of the head and neck to reduce salivary gland dysfunction
-
McDonald S, Meyerowitz C, Smudzin T, Rubin P. Preliminary results of a pilot study using WR-2721 before fractionated irradiation of the head and neck to reduce salivary gland dysfunction. Int J Radiat Oncol Biol Phys 1994;29:747-54
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.29
, pp. 747-754
-
-
McDonald, S.1
Meyerowitz, C.2
Smudzin, T.3
Rubin, P.4
-
22
-
-
0343690945
-
Enhanced recovery from supralethal radiation exposure using combined modality WR-2721 plus recombinant human (rh) G-CSF
-
McVittie TJ, Brandenburg R, Farese AM, Patchen ML, Weiss J. Enhanced recovery from supralethal radiation exposure using combined modality WR-2721 plus recombinant human (rh) G-CSF. Proc Am Assoc Cancer Res 1992;33:505
-
(1992)
Proc Am Assoc Cancer Res
, vol.33
, pp. 505
-
-
McVittie, T.J.1
Brandenburg, R.2
Farese, A.M.3
Patchen, M.L.4
Weiss, J.5
-
23
-
-
0027240386
-
Hematopoietic growth factors and chemoprotectants: Should we move toward a two-step process for phase I clinical trials?
-
Merrouche Y, Catimel G, Clavel M. Hematopoietic growth factors and chemoprotectants: should we move toward a two-step process for phase I clinical trials? Ann Oncol 1993;4:471-4
-
(1993)
Ann Oncol
, vol.4
, pp. 471-474
-
-
Merrouche, Y.1
Catimel, G.2
Clavel, M.3
-
24
-
-
0021718290
-
Inhibilion of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
-
Milas L, Hunter NR, Stephens LC, Peters LJ. Inhibilion of radiation carcinogenesis in mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid. Cancer Res 1984;44:5567-9
-
(1984)
Cancer Res
, vol.44
, pp. 5567-5569
-
-
Milas, L.1
Hunter, N.R.2
Stephens, L.C.3
Peters, L.J.4
-
25
-
-
0020324128
-
The modification of melphalan toxicity in tumor-bearing mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (WR 2721)
-
Millar J, McElwain T, Clutterbuck R, Wist E. The modification of melphalan toxicity in tumor-bearing mice by S-2-(3-aminopropylamino)-ethylphosphorothioic acid (WR 2721). Am J Clin Oncol 1982;5:321-8
-
(1982)
Am J Clin Oncol
, vol.5
, pp. 321-328
-
-
Millar, J.1
McElwain, T.2
Clutterbuck, R.3
Wist, E.4
-
26
-
-
0023948344
-
Cisplatin neuropathy. Risk factors, prognosis and protection by WR-2721
-
Mollman JE, Glover DJ, Hogan WM, Furman RE. Cisplatin neuropathy. Risk factors, prognosis and protection by WR-2721. Cancer 1988;61:2129-5
-
(1988)
Cancer
, vol.61
, pp. 2129-2135
-
-
Mollman, J.E.1
Glover, D.J.2
Hogan, W.M.3
Furman, R.E.4
-
27
-
-
0022551072
-
Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol
-
Nagy B, Dale PJ, Grdina DJ. Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol. Cancer Res 1986;46:1132-5
-
(1986)
Cancer Res
, vol.46
, pp. 1132-1135
-
-
Nagy, B.1
Dale, P.J.2
Grdina, D.J.3
-
29
-
-
0029090540
-
Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (WR-2721): Preclinical aspects
-
Peters GJ, Van der Vijgh WJF. Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (WR-2721): preclinical aspects. Eur J Cancer 1995;31A (suppl 1):S1-S7
-
(1995)
Eur J Cancer
, vol.31 A
, Issue.1 SUPPL.
-
-
Peters, G.J.1
Van Der Vijgh, W.J.F.2
-
30
-
-
0010041620
-
Randomized phase II study of weekly cisplatin with or without amifostine in patients with advanced head and neck cancer
-
Planting AST, Vermorken JB, Catinel G et al. Randomized phase II study of weekly cisplatin with or without amifostine in patients with advanced head and neck cancer. Eur J Cancer 1995; 31A(suppl 5):S85
-
(1995)
Eur J Cancer
, vol.31 A
, Issue.5 SUPPL.
-
-
Planting, A.S.T.1
Vermorken, J.B.2
Catinel, G.3
-
31
-
-
0000760692
-
Localized areas of high alkaline phosphatase acticity in endothelium of arteries
-
Romanul FCA, Bannister RG. Localized areas of high alkaline phosphatase acticity in endothelium of arteries. Nature 1962;195:611-2
-
(1962)
Nature
, vol.195
, pp. 611-612
-
-
Romanul, F.C.A.1
Bannister, R.G.2
-
32
-
-
0030013080
-
Amifostine, cisplatin and vinblastine in metastatic non-small cell lung cancer: A report of high response rates and prolonged survival
-
Schiller JH, Storer B, Berlin J et al. Amifostine, cisplatin and vinblastine in metastatic non-small cell lung cancer: a report of high response rates and prolonged survival. J Clin Oncol 1996;14:1913-21
-
(1996)
J Clin Oncol
, vol.14
, pp. 1913-1921
-
-
Schiller, J.H.1
Storer, B.2
Berlin, J.3
-
33
-
-
0026716746
-
The current status of toxicity protectants in cancer therapy
-
Schuchter LM, Luginbuhl WE, Meropol NJ. The current status of toxicity protectants in cancer therapy. Semin Oncol 1992; 19:742-51
-
(1992)
Semin Oncol
, vol.19
, pp. 742-751
-
-
Schuchter, L.M.1
Luginbuhl, W.E.2
Meropol, N.J.3
-
35
-
-
0022633842
-
Measurement of S-2-(3-aminopropyl-amino) ethanethiol (WR-1065) in blood and tissue
-
Shaw LM, Bonner HS, Turrisi A, Norfleet AL, Kligerman M. Measurement of S-2-(3-aminopropyl-amino) ethanethiol (WR-1065) in blood and tissue. J Liq Chromatogr 1986;9:8445-59
-
(1986)
J Liq Chromatogr
, vol.9
, pp. 8445-8459
-
-
Shaw, L.M.1
Bonner, H.S.2
Turrisi, A.3
Norfleet, A.L.4
Kligerman, M.5
-
37
-
-
0028364704
-
Amifostine (WR-2721) shortens the engraftment time of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support
-
Shpall EJ, Stemmer SM, Hami L et al. Amifostine (WR-2721) shortens the engraftment time of 4-hydroperoxycyclophosphamide-purged bone marrow in breast cancer patients receiving high-dose chemotherapy with autologous bone marrow support. Blood 1994;83:3132-7
-
(1994)
Blood
, vol.83
, pp. 3132-3137
-
-
Shpall, E.J.1
Stemmer, S.M.2
Hami, L.3
-
38
-
-
0025997247
-
Ifosfamide continuous infusion plus etoposide in the treatment of elderly patients with aggressive lymphoma: A phase II study
-
Tigaud JD, Demolombe S, Bastion Y, Bryon PA, Coiffier B. Ifosfamide continuous infusion plus etoposide in the treatment of elderly patients with aggressive lymphoma: a phase II study. Hematol Oncol 1991;9:225-33
-
(1991)
Hematol Oncol
, vol.9
, pp. 225-233
-
-
Tigaud, J.D.1
Demolombe, S.2
Bastion, Y.3
Bryon, P.A.4
Coiffier, B.5
-
39
-
-
0028323126
-
Effects of the modulating agent WR-2721 on myelotoxicity and antitumor activity in carboplatin-treated mice
-
Treskes M, Boven E, Van de Loosdrecht AA et al. Effects of the modulating agent WR-2721 on myelotoxicity and antitumor activity in carboplatin-treated mice. Eur J Cancer 1994;30A:183-7
-
(1994)
Eur J Cancer
, vol.30 A
, pp. 183-187
-
-
Treskes, M.1
Boven, E.2
Van De Loosdrecht, A.A.3
-
40
-
-
0026505855
-
Effects of the modulating agent WR-2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro in comparison ot the effects of thiosulfate and diethyldithiocarbamate
-
Treskes M, Nijtmans LGJ, Fichtinger-Schepman AMJ, Van der Vijgh WJF. Effects of the modulating agent WR-2721 and its main metabolites on the formation and stability of cisplatin-DNA adducts in vitro in comparison ot the effects of thiosulfate and diethyldithiocarbamate. Biochem Pharmacol 1992;43:1013-9
-
(1992)
Biochem Pharmacol
, vol.43
, pp. 1013-1019
-
-
Treskes, M.1
Nijtmans, L.G.J.2
Fichtinger-Schepman, A.M.J.3
Van Der Vijgh, W.J.F.4
-
41
-
-
0017101767
-
Distribution of 35S-labeled WR-2721 in normal and malignant tissues of the mouse
-
Utley JF, Marlowe C, Waddell WJ. Distribution of 35S-labeled WR-2721 in normal and malignant tissues of the mouse. Radiat Res 1976;68:284-91
-
(1976)
Radiat Res
, vol.68
, pp. 284-291
-
-
Utley, J.F.1
Marlowe, C.2
Waddell, W.J.3
-
42
-
-
0020413641
-
Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721
-
Valeriote F, Token S. Protection and potentiation of nitrogen mustard cytotoxicity by WR-2721. Cancer Res 1982;42:4330-1
-
(1982)
Cancer Res
, vol.42
, pp. 4330-4331
-
-
Valeriote, F.1
Token, S.2
-
43
-
-
0027942635
-
Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (Ethyol): Preclinical aspects
-
Van der Vijgh, Peters GJ. Protection of normal tissues from the cytotoxic effects of chemotherapy and radiation by amifostine (Ethyol): preclinical aspects. Semin Oncol 1994;21(suppl 11):2-7
-
(1994)
Semin Oncol
, vol.21
, Issue.11 SUPPL.
, pp. 2-7
-
-
Van Der Vijgh1
Peters, G.J.2
-
46
-
-
0019424730
-
Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by WR-2721
-
Wassermann TH, Philips TL, Ross G, Kane LJ. Differential protection against cytotoxic chemotherapeutic effects on bone marrow CFUs by WR-2721. Cancer Clin Trials 1981;4:3-6
-
(1981)
Cancer Clin Trials
, vol.4
, pp. 3-6
-
-
Wassermann, T.H.1
Philips, T.L.2
Ross, G.3
Kane, L.J.4
-
47
-
-
0015371093
-
Radioprotective and toxic effects of S-2-(3 aminopropylamino) ethylphosphorothioic acid (WR-2721) on the development of immunocompetent cells
-
Yuhas JM. Radioprotective and toxic effects of S-2-(3 aminopropylamino) ethylphosphorothioic acid (WR-2721) on the development of immunocompetent cells. Cell Immunol 1972;4:256-63
-
(1972)
Cell Immunol
, vol.4
, pp. 256-263
-
-
Yuhas, J.M.1
-
48
-
-
0018839016
-
Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
-
Yuhas JM. Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid. Cancer Res 1980;40:1519-24
-
(1980)
Cancer Res
, vol.40
, pp. 1519-1524
-
-
Yuhas, J.M.1
|