Abnormal cerebral glucose metabolism in HIV-1 seropositive subjects with and without dementia

Journal of Nuclear Medicine

Volumn 37, Issue 7, 1996, Pages 1133-1141

  Rottenberg, David A ^a   Sidtis, John J ^b   Strother, Stephen C ^b   Schaper, Kirt A ^b   Anderson, Jon R ^b   Nelson, Mary J ^b   Price, Richard W ^b  

^a VA MEDICAL CENTER   (United States)

^b NONE

Author keywords

fluorine 18 fluorode oxyglucose; human immunodeficiency virus; PET; scaled subprofile model

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AIDS RELATED COMPLEX; ARTICLE; BASAL GANGLION; BRAIN ATROPHY; BRAIN METABOLISM; BRAIN SCINTISCANNING; CLINICAL ARTICLE; DEMENTIA; FEMALE; GLUCOSE METABOLISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOTOPE TRACING; MALE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL;

ADULT; AIDS DEMENTIA COMPLEX; BRAIN; CASE-CONTROL STUDIES; DEOXYGLUCOSE; FEMALE; FLUORINE RADIOISOTOPES; FLUORODEOXYGLUCOSE F18; FOLLOW-UP STUDIES; GLUCOSE; HIV SEROPOSITIVITY; HIV-1; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0029758933     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Albert ML, Feldman RG, Willis AL. The "subcortical dementia" of progressive supranuclear palsy. J Neurol Neurosurg Psychiat 1974;37:121-130.
2. Cummings JL, Benson DF. Subcortical dementia: review of an emerging concept. Arch Neurol 1984;41:874-879.
3. Navia BA, Jordan BD, Price RW. The AIDS dementia complex: I. Clinical features. Ann Neurol 1986;19:517-524.
4. Price RW, Brew B, Sidtis J, Rosenblum M, Scheck AC, Cleary P. The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. Science 1988;239:586-592.
5. Navia BA. The AIDS dementia complex. In: Cummings JL, ed. Subcortical dementia. New York: Oxford University Press; 1990:181-198.
6. Navia BA, Cho ES, Petito CK, Price RW. The AIDS dementia complex: II. Neuropathology. Ann Neurol 1986;9:525-535.
7. Lantos PL, McLaughlin JE, Scholtz CL, Berry CL, Tighe JR. Neuropathology of the brain in HIV infection. Lancet 1989;1:309-311.
8. Budka H. Neuropathology of human immunodeficiency virus infection. Brain Pathol 1991;1:163-175.
9. Rottenberg DA, Moeller JR, Strother SC, et al. The metabolic pathology of the AIDS dementia complex. Ann Neurol 1987;22:700-706.
10. van Gorp WG, Mandelkern MA, Gee M, Hinkin CH, et al. Cerebral metabolic dysfunction in AIDS: findings in a sample with and without dementia. J Neuropsychiat 1992;4:280-287.
11. Price RW, Brew BJ. The AIDS dementia complex. J Infect Dis 1988;158:1079-1083.
12. Price RW, Sidtis JJ. Evaluation of the AIDS dementia complex in clinical trials. J AIDS 1990;3(suppl 2):S51-S60.
13. Sidtis JJ, Gatsonis C, Price RW, et al. Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. Ann Neurol 1993;33:343-349.
14. Sidtis, JJ. Evaluation of the AIDS dementia complex in adults. In: Price RW, Perry SW, eds. HIV, AIDS and the Brain. New York: Raven Press; 1994:273-287.
15. Spinks TJ, Jones T, Bailey DL, et al. Physical performance of a positron tomograph for brain imaging with retractable septa. Phys Med Biol 1992;37:1637-1655.
16. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. New York: Thieme Medical Publishers; 1988.
17. Strother SC, Anderson JR, Xu X-L, Liow J-S, Bonar DC, Rottenberg DA. Quantitative comparisons of image registration techniques based on high-resolution MRI of the brain. J Comput Assist Tomogr 1994;18:954-962.
18. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure and normal values in the conscious and anesthetized albino rat. J Neurochem 1977;28:897-916.
19. 18F]2-fluoro-2-deoxy-D-glucose. Validation of method. Ann Neurol 1979;6:371-388.
20. Brooks RA. Alternative formula for glucose utilization using labeled deoxyglucose. J Nucl Med 1982;23:538-539.
21. 11C]deoxyglucose. J Cereb Blood Flow Metab 1985;5:178-192.
22. 18F]fluorodeoxyglucose positron emission tomographic region of interest data. J Cereb Blood Flow Metab 1991;11:A83-A88.
23. Woods RP, Mazziotta JC, Cherry SR. Automated image registration. In: Uemura K, Lassen NA, Jones T, Kanno I, eds. Proceedings of brain PET '93 AKITA: quantification of brain function. Amsterdam: Excerpta Medica; 1993;391-398.
24. Moeller JR, Strother SC. A regional covariance approach to the analysis of functional patterns in positron emission tomographic data. J Cereb Blood Flow Metab 1991;11: A121-A135.
25. Jackson JE. A user's guide to principal components. New York: John Wiley; 1991.
26. Gollob HF. A statistical model which combines features of factor analytic and analysis of variance techniques. Psychometrika 1968;38:555-569.
27. Eidelberg D, Moeller JR, Ishikawa T, et al. Assessment of disease severity in Parkinsonism with fluorine-18-fluorodeoxyglucose and PET. J Nucl Med 1995;36: 378-383.
28. Mardia KV, Kent JT, Bibby JM. Multivariate Analysis. New York: Academic Press; 1989:318-320.
29. Strother SC, Moeller JR, Sidtis JJ, Rottenberg DA. Using principal component analysis to identify a disease independent pattern of cerebral metabolic activation: the reticular activating system? In: Uemura K, Lassen NA, Jones T, Kanno I, eds. Proceedings of brain PET '93 AKITA: quantification of brain function. Amsterdam: Excerpta Medica; 1993:491-495.
30. Marder K, Liu X, Stern Y, et al. Neurologic signs and symptoms in a cohort of homosexual men followed for 4.5 yr. Neurology 1995;45:261-267.
31. Snedecor GW, Cochran WG. Statistical methods, 7th ed. Ames: Iowa State University Press; 1980.
32. Rehm K, Strother SC, Anderson JR, Schaper K, Rottenberg DA. Display of merged multimodality brain images using interleaved pixels with independent color scales. J Nucl Med 1994;35:1815-1821.