Role of CYP1A2 in caffeine pharmacokinetics and metabolism: Studies using mice deficient in CYP1A2

Pharmacogenetics

Volumn 6, Issue 4, 1996, Pages 291-296

  Buters, Jeroen T M ^a   Tang, Bing Kou ^b   Pineau, Thierry ^a,c   Gelboin, Harry V ^a   Kimura, Shioko ^a   Gonzalez, Frank J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c CEMAGREF   (France)

Author keywords

Caffeine; CYP1A2; Knockout mice; Metabolism; Pharmacokinetics; Urine

Indexed keywords

1 METHYLURIC ACID; 1 METHYLXANTHINE; ALANINE AMINOTRANSFERASE; ALBUMIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CAFFEINE; CREATININE; CYTOCHROME P450 ISOENZYME; DRUG METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEMETHYLATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG URINE LEVEL; ENZYME DEFICIENCY; GENE DELETION; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAPERITONEAL DRUG ADMINISTRATION; KIDNEY FUNCTION; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0029758198     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199608000-00002     Document Type: Article

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