p53 protein expression or protein function? Re: AWWAD et al. IJROBP 34(2):323-332; 1996 [1]

International Journal of Radiation Oncology Biology Physics

Volumn 35, Issue 5, 1996, Pages 1123-1124

  Bristow, R G ^a   Benchimol, S ^a   Hill, R ^a  

^a UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; PROTEIN P53; RETINOBLASTOMA PROTEIN;

ANIMAL CELL; APOPTOSIS; CANCER CELL CULTURE; CELL CYCLE; CLONOGENIC ASSAY; DNA DAMAGE; DNA SEQUENCE; GENE MUTATION; HUMAN; HUMAN CELL; IONIZING RADIATION; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RADIOSENSITIVITY; RAT; TUMOR SUPPRESSOR GENE;

EID: 0029758044     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/0360-3016(96)85887-1     Document Type: Letter

References (18)

1. S. Awwad E. Jaros J. Somes J. Lunec p53 overexpression in head and neck carcinoma and radiotherapy results Int. J. Rad. Oncol. Biol. Phys. 34 2 1996 323 332
2. J. Bergh T. Norberg S. Sjogren A. Lindgren L. Holmberg Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant therapy and radiotherapy Nature Med. 1 10 1995 1029 1034
3. D. Brachman M. Beckett D. Graves D. Haraf E. Vokes R.R. Weichselbaum p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines Cancer Res. 53 1993 3667 3668
4. D.G. Brachman Molecular biology of head and neck cancer Sem. Oncol. 21 3 1994 320 329
5. J. Brennan L. Mao R. Hruban J. Boyle Y. Eby W. Koch S. Goodman D. Sidransky Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck New. Engl. J. Med. 332 7 1995 429 435
6. R.G. Bristow A. Jang J. Peacock S. Chung S. Benchimol R.P. Hill Mutant p53 increases radioresistance in rat embryo fibroblasts simultaneously transfected with HPV 16-E7 and/or activated H-ras Oncogene 9 1994 1527 1536
7. L. Cox D.P. Lane Tumour suppressors, kinases and clamps: How p53 regulates the cell cycle in response to DNA damage BioEssays 17 6 1995 501 508
8. T. Frebourg S.H. Friend The importance of p53 mutations in human cancer: Is there more than circumstantial evidence? J. Nat. Cancer Inst. 85 1993 1554 1557
9. J. Kovach A. Hartmann H. Blaszyk J. Cunningham D. Schaid S.S. Sommer Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer can have important prognostic value Proc. Nat. Acad. Sci. 93 1996 1093 1096
10. A. Kyritsis M. Bondy K. Hess J. Cunningham D. Zhu C. Amos W. Yung V. Levin J. Bruner Prognostic significance of p53 immunoreactivity in patients with glioma Clin. Cancer Res. 1 1995 1617 1622
11. J. Langendijk F. Thunnissen R. Lamers J. de Jong G. ten Velde E. Wouters The prognostic significance of p53 protein in stage III non-small cell lung cancer treated by radiotherapy Radiother. Oncol. 36 1995 218 224
12. A. McIlwrath P. Vasey G. Ross R. Brown Cell cycle arrests and radiosensitivity of human tumour cell lines: Dependence on wild type p53 for radiosensitivity Cancer Res. 54 1994 3718 3722
13. K. Ory Y. Legros C. Auguin T. Soussi Analysis of the most representative tumor-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation E.M.B.O.J. 13 1994 3496 3504
14. J. Peacock S. Chung R.G. Bristow R.P. Hill S. Benchimol The p53-mediated G1 checkpoint is retained in tumorigenic rat embryo fibroblast clones transformed by the human papillomavirus type 16 E7 gene and EJ-ras Mol. Cell. Biol. 15 3 1995 1446 1454
15. D.M. Schin J. Kim J. Ro J. Hittelman J. Roth W. Hong W. Hittelman Activation of p53 gene expression in premalignant lesions during head and neck tumorigenesis Cancer Res. 54 1994 321 326
16. N. Tsang H. Nagasawa C. Il J.B. Little Abrogation of p53 function by transfection of HPV 16-E6 enhances the resistance of human diploid fibroblasts to ionizing radiation Oncogene 10 1995 2403 2408
17. G. Wilson P. Richman S. Dische M. Saunders B. Robinson F. Daley D. Ross p53 status of head and neck cancer: Relation to biological characteristics and outcome of radiotherapy Brit. J. Cancer 71 1995 1248 1252
18. L. Xu Y. Chen A. Huvos Zlotolow W. Rettig L. Old P. Garin-Chesa Overexpression of p53 protein in squamous cell carcinomas of head and neck without apparent gene mutations Diag. Mol. Path. 3 2 1994 83 92