Anion channel blockers inhibit swelling-activated anion, cation, and nonelectrolyte transport in HeLa cells

American Journal of Physiology - Cell Physiology

Volumn 271, Issue 2 40-2, 1996, Pages

  Hall, James A ^b   Kirk, Julie ^b   Potts, Jennifer R ^b   Rae, Caroline ^b   Kirk, Kiaran ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b NONE

Author keywords

osmolyte; sorbitol; taurine; volume regulation

Indexed keywords

1,9 DIDEOXYFORSKOLIN; 4,4' DIISOTHIOCYANATOSTILBENE 2,2' DISULFONIC ACID; ANION CHANNEL; NIFLUMIC ACID; QUININE; SORBITOL; TAMOXIFEN; TAURINE;

ARTICLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; ELECTROLYTE TRANSPORT; HELA CELL; HUMAN; HUMAN CELL; HYPOTHESIS; OSMOSIS; PRIORITY JOURNAL;

CINCHONA PUBESCENS;

EID: 0029757294     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1996.271.2.c579     Document Type: Article

References (39)

1. Ballatori, N., A, T. Truong, P. S. Jackson, K. Strange, and J. L. Boyer. ATP depletion and inactivation of an ATP-sensitive taurine channel by classic ion channel blockers. Mol. Pharmacol. 48: 472-476, 1995.
2. Banderali, U., and G. Roy. Anion channels for amino acids in MDCK cells. Am. J. Physiol. 263 (Cell Physiol. 32): C1200-C1207, 1992.
3. Bondii, A. Van der Waals volumes and radii. J. Phys. Chem. 68: 441-451, 1964.
4. + transport via two functionally distinct pathways in eel erythrocytes. Am. J. Physiol. 270 (Regulatory Integrative Comp. Physiol. 39): R61-R70, 1996.
5. Cabantchik, Z. I., and R. Greger. Chemical probes for anion transporters of mammalian cell membranes. Am. J. Physiol. 262 (Cell Physiol. 31): C803-C827, 1992.
6. + currents in HeLa cells. Pfluegers Arch. 430: 168-180, 1995.
7. Diaz, M., M. A. Valverde, C. F. Higgins, C. Rucareanu, and F. V. Sepulveda. Volume-activated chloride channels in HeLa cells are blocked by verapamil and dideoxyforskolin. Pfluegers Arch. 422: 347-353, 1993.
8. Furlong, T. J., T. Moriyama, and K. R. Spring. Activation of osmolyte efflux from cultured renal papillary epithelial cells. J. Membr. Biol. 123: 269-277, 1991.
9. Gill, D. R., S. C. Hyde, C. F. Higgins, M. A. Valverde, G. M. Mintenig, and F. V. Sepulveda. Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein. Cell 71: 23-32, 1992.
10. + fluxes in the isolated perfused rat liver: characterization by ion transport inhibitors. Am. J. Physiol. 257 (Gastrointest. Liver Physiol. 20): G357-G363, 1989.
11. Hall, A. C. Volume-sensitive taurine transport in bovine articular chondrocytes. J. Physiol. Lond. 484: 677-687, 1995.
12. Hall, J. A., J. Kirk, J. R. Potts, C. D. Rae, J. I. Vandenberg, and K. Kirk. Swelling-activated transport of diverse solutes in a human cancer cell line (Abstract). J. Physiol. Lond. 487.P: 96P, 1995.
13. Haynes, J. K., and L. Goldstein. Volume-regulatory amino acid transport in erythrocytes of the little skate, Raja erinacea. Am. J. Physiol. 265 (Regulatory Integrative Comp. Physiol. 34): R173-R179, 1993.
14. - and ATP. Am. J. Physiol. 270 (Cell Physiol. 39): C57-C66, 1996.
15. Jackson, P. S., R. Morrison, and K. Strange. The volume-sensitive organic osmolyte-anion channel VSOAC is regulated by nonhydrolytic ATP binding. Am. J. Physiol. 267 (Cell Physiol. 36): C1203-C1209, 1994.
16. Jackson, P. S., and K. Strange. Volume-sensitive anion channels mediate swelling-activated inositol and taurine efflux. Am. J. Physiol. 265 (Cell Physiol. 34): C1489-C1500, 1993.
17. Joyner, S. E., and K. Kirk. Two pathways for choline transport in eel erythrocytes: a saturable carrier and a volume-activated channel. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36): R773-R779, 1994.
18. Kinne, R. K. The role of organic osmolytes in osmoregulation: from bacteria to mammals. J. Exp. Zool. 265: 346-355, 1993.
19. - and taurine efflux from HeLa cells by P-glycoprotein blockers correlates with calmodulin inhibition. J. Biol. Chem. 269: 29389-29394, 1994.
20. Kirk, K., J. C. Ellory, and J. D. Young. Transport of organic substrates via a volume-activated channel. J. Biol. Chem. 267: 23475-23478, 1992.
21. Kirk, K., and H. A. Horner. Novel anion dependence of induced cation transport in malaria- infected erythrocytes. J. Biol. Chem. 270: 24270-24275, 1995.
22. Kirk, K., and J. Kirk. Volume-regulatory taurine release from a human lung cancer cell line: evidence for amino acid transport via a volume-activated chloride channel. FEBS Lett. 336: 153-158, 1993.
23. Lambert, I. H., and E. K. Hoffmann. Cell swelling activates separate taurine and chloride channels in Ehrlich mouse ascites tumor cells. J. Membr. Biol. 142: 289-298, 1994.
24. Lewis, R. A., J. D. H. Bursell, and K. Kirk. Anion-selectivity of the swelling-activated osmolyte channel in eel erythrocytes. J. Membr. Biol. 149: 103-111, 1996.
25. McManus, M., C. Serhan, P. S. Jackson, and K. Strange. Ketoconazole blocks organic osmolyte efflux independently of its effect on arachidonic acid. Am. J. Physiol. 267 (Cell Physiol. 36): C266-C271, 1994.
26. Napathorn, S., and K. R. Spring. Further characterization of the sorbitol permease in PAP-HT25 cells. Am. J. Physiol. 267 (Cell Physiol. 36): C514-C519, 1994.
27. Oike, M., G. Droogmans, and B. Nilius. The volume-activated chloride current in human endothelial cells depends on intracellular ATP. Pfluegers Arch. 427: 184-186, 1994.
28. Rasola, A., L. J. V. Galietta, D. C. Gruenert, and G. Romeo. Ionic selectivity of volume-sensitive currents in human epithelial cells. Biochim. Biophys. Acta 1139: 319-323, 1992.
29. Roy, G. Amino acid current through anion channels in cultured human glial cells. J. Membr. Biol. 147: 35-44, 1995.
30. Roy, G., and C. Malo. Activation of amino acid diffusion by a volume-increase in cultured kidney (MDCK) cells. J. Membr. Biol. 130: 83-90, 1992.
31. Sanchez-Olea, R., C. Fuller, D. Benos, and H. Pesantes-Morales. Volume-associated osmolyte fluxes in cell lines with or without the anion exchanger. Am. J. Physiol. 269 (Cell Physiol. 38): C1280-C1286, 1995.
32. Sanchez-Olea, R., M. Morales-Mulia, J. Moran, and H. Pasantes-Morales. Inhibition by polyunsaturated fatty acids of cell volume regulation and osmolyte fluxes in astrocytes. Am. J. Physiol. 269 (Cell Physiol. 38): C96-C102, 1995.
33. - transport in cultured astrocytes. Neurosci. Lett. 156: 141-144, 1993.
34. Siebens, A. W., and K. R. Spring. A novel sorbitol transport mechanism in cultured renal papillary epithelial cells. Am. J. Physiol. 257 (Renal Fluid Electrolyte Physiol. 26): F937-F946, 1989.
35. Strange, K., and P. S. Jackson. Swelling-activated organic osmolyte efflux: a new role for anion channels. Kidney Int. 48: 994-1003, 1995.
36. Strange, K., R. Morrison, L. Shrode, and R. Putnam. Mechanism and regulation of swelling-activated inositol efflux in brain glial cells. Am. J. Physiol. 265 (Cell Physiol. 34): C244-C256, 1993.
37. Tivey, D. R., N. L. Simmons, and J. F. Aiton. Role of passive potassium fluxes in cell volume regulation in cultured HeLa cells. J. Membr. Biol. 87: 93-105, 1985.
38. Weast, R. C. (Editor). Handbook of Chemistry and Physics (56th ed.). Boca Raton, FL: CRC, 1975.
39. Zlatkine, P., G. Moll, A. Blais, A. Loiseau, and C. Le Grimellec. Transport of choline by Madin-Darby canine kidney cells. Biochim. Biophys. Acta 1153: 237-242, 1993.