Role of cis-acting sequences of the ICPO promoter of herpes simplex virus type 1 in viral pathogenesis, latency and reactivation

Journal of General Virology

Volumn 77, Issue 8, 1996, Pages 1853-1863

  Davido, David J ^a   Leib, David A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; CYCLOHEXIMIDE; VIRUS PROTEIN; VIRUS RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORNEA; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; TRANSACTIVATION; TRIGEMINUS GANGLION; VIRUS GENE; VIRUS LATENCY; VIRUS MUTANT; VIRUS PATHOGENESIS; VIRUS REACTIVATION; VIRUS REPLICATION; VIRUS VIRULENCE;

EID: 0029756804     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-77-8-1853     Document Type: Article

References (50)

1. Ackermann, M., Braun, D. K., Pereira L. & Roizman, B. (1984). Characterization of herpes simplex virus 1 α proteins 0, 4, and 27 with monoclonal antibodies. Journal of Virology 52, 108-118.
2. Ackland-Berglund, C. E., Davido, D. J. & Leib D. A. (1995). The roles of the cAMP response element and TATA box in expression of the herpes simplex virus type 1 latency-associated transcripts. Virology 210, 141-151.
3. Bohenzhy, R. A., Lagunoff, M., Roizman, B., Wagner, E. K. & Silverstein, S. (1995). Two overlapping transcription units which extend across the L-S junction of herpes simplex virus type 1. Journal of Virology 69, 2889-2897.
4. Brasier, A. R., Tate, J. E. & Habener, J. F. (1989). Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell lines. BioTechiques 7, 1116-1122.
5. Cai, W. & Schaffer, P. A. (1989). Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA. Journal of Virology 63, 4579-4589.
6. Cai, W. & Schaffer, P. A. (1991). A cellular function can enhance gene expression and plating efficiencies of a mutant defective in the gene for ICP0, a transactivating protein of herpes simplex virus type 1. Journal of Virology 65, 4078-4090.
7. Cai, W. & Schaffer, P. A. (1992). Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells. Journal of Virology 66, 2904-2915.
8. Cai, W., Astor, T. L., Liptak, L. M., Cho, C., Coen, D. M. & Schaffer, P. A. (1993). The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency. Journal of Virology 67, 7501-7512.
9. Chou, J. & Roizman, B. (1986). The terminal a sequence of the herpes simplex virus genome contains the promoter of a gene located in the repeat sequences of the L component. Journal of Virology 57, 629-637.
10. Clements, J. B. & Stow, N. D. (1989). A herpes simplex virus type 1 mutant containing a deletion within immediate early gene 1 is latency-competent in mice. Journal of General Virology 70, 2501-2506.
11. Coen, D. M., Irmiere, A. F., Jacobson, J. G. & Kerns, K. M. (1989). Low levels of herpes simplex virus thymidine-thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model. Virology 168, 221-231.
12. Douville, P., Hagmann, M., Georgiev, O. & Schaffner, W. (1995). Positive and negative regulation at the herpes simplex virus ICP4 and ICP0 TAATGARAT motifs. Virology 207, 107-116.
13. Everett, R. D. (1984). Transactivation of transcription by a herpes simplex virus product: requirement for two HSV-1 immediate-early polypeptides for maximal activity. EMBO Journal 3, 3135-3141.
14. Everett, R. D. & Orr, A. (1991). The Vmw 175 binding site in the IE-1 promoter has no apparent role in the expression of Vmw110 during herpes simplex virus type 1 infection. Virology 180, 509-517.
15. Faber, S. W. & Wilcox, K. W. (1986). Association of herpes simplex virus regulatory protein ICP4 with sequences spanning the ICP4 gene transcription initiation site. Nucleic Acids Research 14, 6067-6083.
16. Gelman, I. H. & Silverstein, S. (1986). Co-ordinate regulation of herpes simplex virus gene expression is mediated by the functional interaction of two immediate early gene products. Journal of Molecular Biology 191, 395-409.
17. Goldstein, D. J. & Weller, S. K. (1988). Herpes simplex virus type 1-induced ribonucleotide reductase activity is dispensable for virus growth and DNA synthesis: isolation and characterization of an ICP6 lacZ insertion mutant. Journal of Virology 62, 196-205.
18. Honess, R. W. & Roizman, B. (1973). Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpesvirus polypeptides in infected cells. Journal of Virology 12, 1346-1365.
19. Honess, R. W. & Roizman, B. (1974). Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. Journal of Virology 14, 8-19.
20. Jones, K. A. & Tjian, R. (1985). Sp1 binds to promoter sequences and activates herpes simplex virus 'immediate-early' gene transcription in vitro. Nature 317, 179-182.
21. Katz, J. P., Bodin, E. T. & Coen, D. M. (1990). Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants. Journal of Virology 64, 4288-4295.
22. Kosz-Vnenchak, M., Jacobson, J., Coen, D. M. & Knipe, D. M. (1993). Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons. Journal of Virology 67, 5383-5393.
23. Kristie, T. M. & Roizman, B. (1987). Host cell proteins bind to the cisacting site required for virion-mediated induction of herpes simplex virus 1 α genes. Proceedings of the National Academy of Sciences, USA 84, 71-75.
24. 134.5 gene and transcribed by an RNA 3′ coterminal with the unspliced latency-associated transcript. Journal of Virology 68, 6021-6028.
25. Leib, D. A., Coen, D. M., Bogard, C. L., Hicks, K. A., Yager, D. R., Knipe, D. M., Tyler, K. L & Schaffer, P. A. (1989). Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. Journal of Virology 63, 759-768.
26. McKnight, J. L. C., Kristie, T. M. & Roizman, B. (1987). Binding of the virion protein mediating α gene induction in herpes simplex virus-infected cells to its ris site requires cellular proteins. Proceedings of the National Academy of Sciences, USA 84, 7061-7065.
27. Meredith, M., Orr, A. & Everett, R. D. (1994). Herpes simplex virus type 1 immediate-early protein Vmw110 binds strongly and specifically to a 135-kDa cellular protein. Virology 200, 457-469.
28. O'Rourke, D. & O'Hare, P. (1993). Mutually exclusive binding of two cellular factors within a critical promoter region of the gene for the IE110k protein of herpes simplex virus. Journal of Virology 67, 7201-7214.
29. Perry, L. J. & McGeoch, D. J. (1988). The DNA sequences of the long repeat region and adjoining parts of the long unique region in the genome of herpes simplex virus type 1. Journal of General Virology 69, 2831-2846.
30. Quinlan, M. P. & Knipe, D. M. (1985). Stimulation of expression of a herpes simplex virus DNA-binding protein by two viral functions. Molecular and Cellular Biology 5, 957-963.
31. Rader, K. A., Ackland-Berglund, C. E., Kelvin Miller, J., Repose, J. S. & Leib, D. A. (1993). In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts. Journal of General Virology 74, 1859-1869.
32. Ralph, Jr, W. M., Cabatingan, M. S. & Schaffer, P. A. (1994). Induction of herpes simplex virus type 1 immediate-early gene expression by a cellular activity expressed in vero and NB41A3 cells after growth arrest-release. Journal of Virology 68, 6871-6882.
33. Roizman, R. & Sears, A. E. (1990). Herpes simplex viruses and their replication. In Virology, pp. 1795-1842. Edited by B. N. Fields & D. M. Knipe. New York : Raven Press.
34. Rong, B. L., Libermann, T. A., Kogawa, K., Ghosh, S., Cao, L. X., Pavan-Langston, D. & Dunkel, E. C. (1992). HSV-1 inducible proteins bind to NF-κB-like sites in the HSV-1 genome. Virology 189, 750-756.
35. Rouet, R., Raguenez, G. & Salier, J.-P. (1992). Optimized assays for quantifying transient expressions of co-transfected β-galactosidase and CAT reporter genes. BioTechniques 13, 700-702.
36. Sacks, W. R. & Schaffer, P. A. (1987). Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. Journal of Virology 61, 829-839.
37. Sandri-Goldin, R. M., Levine, M. M. & Glorioso, J. C. (1981). Method for induction of mutations in physically defined regions of the herpes simplex virus genome. Journal of Virology 38, 41-49.
38. Smith, C. A., Marchetti, M. E., Edmonson, P. & Schaffer, P. A. (1989). Herpes simplex virus type 2 mutants with deletions in the intergenic region between ICP4 and ICP22/47: identification of nonessential cis-acting elements in the context of the viral genome. Journal of Virology 63, 2036-2047.
39. Spivack, J. G., Fareed, M. U., Valyi-Nagy, T., Nash, T. C., O'Keefe, J. S., Gesser, R. M., McKie, E. A., MacLean, A. R., Fraser, N. W. & Brown, S. M. (1995). Replication, establishment of latent infection, expression of the latency-associated transcripts and explant reactivation of herpes simplex virus type 1 γ34.5 mutants in a mouse eye model. Journal of General Virology 76, 321-332.
40. Steiner, I., Spivack, J. G., Deshmane, S. L., Ace, C. I., Preston, C. M. & Fraser, N. W. (1990). A herpes simplex virus type 1 mutant containing a non-transducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia. Journal of Virology 64, 1630-1638.
41. Stevens, J. G. (1989). Human herpesviruses: a consideration of the latent state. Microbiological Reviews 53, 318-332.
42. Stevens, J. G., Wagner, E. K., Devi-Rao, G., Cook, M. L. & Feldman, L. (1987). RNA complementary to herpesvirus α-gene mRNA is predominant in latently infected neurons. Science 235, 1056-1059.
43. Stow, N. D. & Stow, E. C. (1986). Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. Journal of General Virology 67, 2571-2585.
44. Strelow, L. I. & Leib, D. A. (1995). Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis. Journal of Virology 69, 6779-6786.
45. Takasu, T., Furata, Y., Sato, K. C., Fukuda, S., Inuyama, Y. & Nagashima, K. (1992). Detection of latent herpes simplex virus DNA and RNA in human geniculate ganglia by the polymerase chain reaction. Ada Otolaryngologica 112, 1004-1011.
46. Tebas, P., Stabell, E. C. & Olivo, P. D. (1995). Antiviral susceptibility testing with a cell line which expresses β-galactosidase after infection with herpes simplex virus. Antimicrobial Agents and Chemotherapy 39, 1287-1291.
47. Yao, F. & Courtney, R. J. (1992). Association of ICP0 but not ICP27 with purified virions of herpes simplex virus type 1. Journal of Virology 66, 2709-2716.
48. Yeh, L. & Schaffer, P. A. (1993). A novel class of transcripts expressed with late kinetics in the absence of ICP4 spans the junction between the long and short segments of the herpes simplex virus type 1. Journal of Virology 67, 7373-7382.
49. + T lymphocytes. Cell 77, 525-535.
50. Zhu, Z., Cai, W. & Schaffer, P. A. (1994). Cooperativity among herpes simplex virus type 1 immediate-early regulatory proteins: ICP4 and ICP27 affect the intracellular localization of ICP0. Journal of Virology 68, 3027-3040.