Neutralization of bee venom lethality by immune serum antibodies

American Journal of Tropical Medicine and Hygiene

Volumn 55, Issue 2, 1996, Pages 197-201

  Schumacher, Michael J ^a   Egen, Ned B ^b   Tanner, David ^b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITOXIN; BEE VENOM; IMMUNOGLOBULIN E ANTIBODY; MELITTIN; PHOSPHOLIPASE A2;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ANTIBODY PRODUCTION; ARTICLE; BEE STING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNIZATION; MOUSE; NONHUMAN; RABBIT; TOXIN ANALYSIS;

ANIMALIA; APIS MELLIFERA; APOIDEA; ORYCTOLAGUS CUNICULUS;

EID: 0029756591     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.1996.55.197     Document Type: Article

References (37)

1. Guzman-Novoa E, Page RE, 1994. Impact of Africanized bees on Mexican beekeeping. Am Bee J 134: 101-106.
2. Rinderer TE, Oldroyd BP, Sheppard WS, December 1993. Africanized bees in the U.S. Sci Am 269: 84-90.
3. Jex-Blake AJ, 1942. Bee-stings. E Afr Med J 19: 74-86.
4. Koszalka MF, 1949. Multiple bee stings with hemoglobinuria and recovery. Report of a case. Bull US Army Med Dept 9: 212-217.
5. Murray JA, 1964. A case of multiple bee stings. Cent Afr Med J 10: 249-251.
6. Moret C, Enzel C, Leclercq M, Bosson L, Lecomte J, 1983. Un cas d'envenimation mortelle par piqures multiples d'abeilles (Apis mellifera L). Rev Med Liege 38: 815-822.
7. Humblet Y, Sonnet J, van Ypersele de Strihou C, 1982. Bee stings and acute tubular necrosis. Nephron 31: 187-188.
8. Mejia G, Arbelaez M, Henao JE, Sus AA, Arango JL, 1986. Acute renal failure due to multiple stings by Africanized bees. Ann Intern Med 104: 210-211.
9. Patrick A, Roberts L, Poon-King P, Jeelal V, 1987. Acute renal failure due to multiple stings by Africanized bees. Report of the first case in Trinidad. West Indian Med J 36: 43-44.
10. Ramanathan M, Lam HS, 1990. Acute renal failure due to multiple bee stings -case reports. Med J Malaysia 45: 344-346.
11. Tumwine JK, Nkrumah FK, 1990. Acute renal failure and dermal necrosis due to bee stings: report of a case in a child. Cent Afr J Med 36: 202-204.
12. Beccari M, 1992. Unusual case of anuria due to African bee stings. Int J Artificial Organs 15: 281-283.
13. Franca FOS, Benvenuti LA, Fan HW, Dos Santos DR, Hain SH, Picchi-Martins FR, Cardoso JLC, Kamiguti AS, Theakston RDG, Warrell DA, 1994. Severe and fatal attacks by "killer" bees (Africanized honey bees - Apis mellifera scutellata) in Brazil: clinicopathological studies with measurement of serum venom concentrations. Q J Med 87: 269-282.
14. Kemeny DM, Harries MG, Youlten LJF, Mackenzie-Mills M, Lessof MH, 1983. Antibodies to purified venom proteins and peptides. I. Development of a highly specific RAST for bee venom antigens and its application to bee sting allergy. J Allergy Clin Immunol 71: 505-514.
15. Schumacher MJ, Schmidt JO, Egen NB, Lowry JE, 1990. Quantity, analysis and lethality of European and Africanized honey bee venoms. Am J Trop Med Hyg 43: 79-86.
16. Harlow E, Lane D, 1988. Antibodies. A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Press, 298-299.
17. Check IJ, Piper M, 1986. Quantitation of immunoglobulins. Rose NR, Friedman H, Fahey JL, eds Manual of Clinical Immunology. Third Edition. Washington, DC: American Society of Microbiology, 138-151.
18. Kemeny DM, 1991. A Practical Guide to ELISA. New York: Pergamon Press, 98-109.
19. Nelson DR, Collins AM, Hellmich RL, Jones RT, Helm RM, Squillace DL, Yunginger JW, 1990. Biochemical and immunological comparison of Africanized and European honeybee venoms. J Allergy Clin Immunol 85: 80-85.
20. Schumacher MJ, Schmidt JO, Egen NB, 1989. Lethality of "killer" bee stings Nature 337: 413.
21. Schumacher MJ, Schmidt JO, Egen NB, Dillon KA, 1992. Biochemical variability of venoms from individual European and Africanized honeybees (Apis mellifera). J Allergy Clin Immunol 90: 59-65.
22. Kind LS, Allaway E, 1982. Enhanced IgE and IgG anti-melittin antibody formation induced by heparin-melittin complexes in mice. Allergy 37: 225-229.
23. 2 and a-amanatin. Toxicon 13: 465-473.
24. Banks BEC, Garmon AJ, Habermann E, 1978. Structure-activity studies on apamin and mast cell degranulating peptide (MCDP)-401. J Physiol (Lond) 284: 160P-161P
25. Ambrus JL, Packman EW, Rossi JV, Ambrus CM, Harrison JWE, 1952. The antagonism and synergism of histamine and antihistamines in mice. J Pharm Pharmacol 4: 466-470.
26. Russell FE, Sullivan JB, Egen NB, Jeter WS, Markland FS, Wingert WA, Bar-Or D, 1985. Preparation of a new antivenin by affinity chromatography. Am J Trop Med Hyg 34: 141-150.
27. Minton SA, Weinstein SA, 1986. Geographic and ontogenic variation in venom of the western diamondback rattlesnake (Crotalus atrox). Toxicon 24: 71-80.
28. Ownby CL, Colberg TR, 1986. Ability of polyvalent (Crotalidae) antivenom to neutralize local myonecrosis induced by Crotalus atrox venom. Toxicon 24: 201-203.
29. Dos Santos MC, D'Imperio Lima MR, Furtado GC, Colletto GM, Kipnis TL, Dias da Silva W, 1989. Purification of F(ab')2 anti-snake venom by caprylic acid: a fast method for obtaining IgG fragments with high neutralization activity, purity and yield. Toxicon 27: 297-303.
30. Kornalik F, Taborska E, 1989. Cross reactivity of mono- and polyvalent antivenoms with Viperidae and Crotalidae snake venoms. Toxicon 27: 1135-1142.
31. Tan NH, Saifuddin MN, Jaafar MI, 1990. Preparation of antibodies to king cobra (Ophiophagus hannah) venom hemorrhagin and investigation of their cross-reactivity. Toxicon 28: 1355-1359.
32. Stiles BG, Lidgerding BC, Sexton FW, Guest SB, 1991. Production and characterization of monoclonal antibodies against Naja naja atra cobrotoxin. Toxicon 29: 1195-1204.
33. Assakura MT, Salamao MG, Puorto G, Mandelbaum FR, 1992. Hemorrhagic, fibrinogenolytic and edema-forming activities of the venom of the colubrid snake Philodryas olfersii (green snake). Toxicon 30: 427-438.
34. Ferreira ML, Moura-da-Silva AM, Mota I, 1992. Neutralization of different activities of venoms from nine species of Bothrops snakes by Bothrops jararaca antivenom. Toxicon 30: 1591-1602.
35. Mandal M, Hati RN, Hati AK, 1993. Neutralization of pathophysiological manifestations of Russell's viper envenoming by antivenom raised against gamma-irradiated toxoid. Toxicon 31: 213-216.
36. Rawat S, Laing G, Smith DC, Theakston D, Landon J, 1994. A new antivenom to treat eastern coral snake (Micrurus fulvius fulvius) envenoming. Toxicon 32: 185-190.
37. Rojas G, Jimenez JM, Gutierrez JM, 1994. Caprylic acid fractionation of hyperimmune horse plasma: description of a simple procedure for antivenom production. Toxicon 32: 351-363.