Psychopharmacology in vivo neurochemistry and pharmacology

British Medical Bulletin

Volumn 52, Issue 3, 1996, Pages 513-526

  Grasby, Paul ^a   Malizia, Andrea ^a   Bench, Chris ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN RECEPTOR; NEUROLEPTIC AGENT; NEUROTRANSMITTER; PSYCHOTROPIC AGENT; RADIOISOTOPE; TRACER;

COMPUTER ASSISTED TOMOGRAPHY; HUMAN; MENTAL DISEASE; NEUROCHEMISTRY; NEUROTRANSMISSION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; RECEPTOR OCCUPANCY; REVIEW; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TOMOGRAPHY;

EID: 0029756186     PISSN: 00071420     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.bmb.a011564     Document Type: Review

References (41)

1. Myers R, Spinks TJ, Luthra SK et al Positron emission tomography. In: Stewart MG. (Ed) Quantitative Methods in Neuroanatomy. New York: Wiley, 1992; 117-61
2. Bailey DL, Zito F, Gilardi MC et al. Performance comparison of a state-of-the-art neuro-PET scanner and a dedicated neuro-PET scanner. Eur J Nucl Med 1994; 21: 381-7
3. 2-dopamine receptors in drug-naive schizophrenia. Science 1986; 234: 1558-63
4. 2 dopamine receptors in neuroleptic naive schizophrenic patients. Arch Gen Psychiatry 1990; 47: 213-9
5. Bench C. Advances in functional imaging. Curr Med Lit Psychiatry 1994; 5: 63-75
6. 11C-NMSP. Psych Res 1995; In press
7. 4 receptor elevated in schizophrenia. Nature 1993; 365: 441-5
8. 4 receptors increased in schizophrenia? J Neurochem 1994; 63: 1756-77
9. Sedvall G, Farde L. Chemical brain anatomy in schizophrenia. Lancet 1995; 346: 743-9
10. 1-dopamine receptor binding in drug naive schizophrenic patients examined by PET. Schizophrenia Res 1995; 15(1,2): 86
11. Pike V. Positron emitting radioligands for studies in vivo-probes for human psychopharmacology. J Psychopharmacol 1993; 7: 139-58
12. 11C at two different positions. Eleventh International Symposium on Radiopharmaceutical Chemistry. J Label Compounds Radiopharm 1995; 37: 316-8
13. 11C-WAY-100635. Eur J Pharmacol 1995; 283: R1-R3
14. Schlegel S, Steinen H, Bockish A et al. Decreased benzodiazepine receptor binding in panic disorder measured by iomazenil SPECT. Arch Psychol Clin Neurosci 1994; 244: 49-51
15. 2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs. Arch Gen Psychiatry 1988; 45: 71-6
16. 2 dopamine receptor occupancy in patients treated with classical neuroleprics and clozapine. Relation to extrapyramidal side effects. Arch Gen Psychiatry 1992; 49: 538-54
17. 11C-raclopride. Psychopharmacology 1993; 112: 308-14
18. 2 dopamine receptor blockade hypothesis of schizophrenia. Lancet 1992; 340: 199-202
19. 2 receptor occupancy in clozapine treated patients demonstrated by PET. Psychopharmacology 1993; 110: 365-7
20. 2 dopamine receptor occupancy in the living human brain: a PET study with risperidone. Psychopharmacology 1993; 110: 265-72
21. Brouillet E, Chavoix C, Bottlaender M et al. In vivo bidirectional modulatory effect of benzodiazepine receptor ligands on GABAergic transmission evaluated by positron emission tomography in non-human primate. Brain Res 1991; 557: 167-76
22. Malizia A, Forse G, Haida A et al A new human (psycho)pharmacology tool: the multiple organs coincidences counter (MOCC). J Psychopharm 1995; 9: 294-306
23. Raichle ME. Circulatory and metabolic correlations of brain function in normal humans. In: Plum F. (Ed) Handbook of Physiology. Section I : The nervous system, vol 5: Higher functions of the brain. New York: Oxford University Press, 1987; 643-74
24. 14C]-deoxyglucose. In: Iversen LL, Iversen SD, Snyder SH. (Eds) Handbook of Psychopharmacology. New York: Plenum, 1982; 321-410
25. Buchsbaum MS , Potkin SG, Siegal BV et al. Striatal metabolic rate and clinical response to neuroleptics in schizophrenia. Arch Gen Psychiatry 1992; 49: 966-74
26. Fristen KJ, Grasby PM, Frith CD et al. Measuring the neuromodulatory effects of drugs in man with positron emission tomography. Neurosci Lett 1992; 141: 106-10
27. Grasby PM, Friston KJ, Bench C et al. The effect of apomorphine and buspirone on regional cerebral blood flow during the performance of a cognitive task - measuring neuromodulatory effects of psychotropic drugs in man. Eur J Neurosci 1992; 4: 1203-12
28. Grasby PM, Friston KJ, Bench C et al. The effect of scopolamine on regional cerebral blood flow during the performance of a memory task. Exp Brain Res 1995; 104: 337-48
29. Foote SL. Extrathalamic modulation of cortical function. Annu Rev Neurosci 1987; 10: 67-95
30. 1 dopamine receptors in prefrontal cortex: involvement in working memory. Science 1991; 251: 947-50
31. Daniel DG, Weinberger DR, Jones DW et al. The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia. J Neurosci 1991; 11: 1907-17
32. Dolan RJ, Fletcher P, Frith C et al. Dopaminergic modulation of a functional deficit in anterior cingulate cortex in schizophrenia. Nature 1995; 378: 180-2
33. Dewey SL, Smith GS, Logan J et al. Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects. Proc Natl Acad Sci USA 1993; 90: 11816-20
34. 11C-raclopride and positron emission tomography. J Neurosci 1992; 12: 3773-80
35. 11C-raclopride in the human brain. Synapse 1994; 16: 255-62
36. Laurelle M, Abi-Dargham A, van Dyck CH et al. SPECT imaging of striatal dopamine release after amphetamine challenge. J Nucl Med 1995; 36: 1182-90
37. Bartenstein PA, Duncan JS, Prevett MC et al. Investigation of the opioid system in absence seizures with positron emission tomography. J Neural Neurosurg Psych 1993; 56: 1295-302
38. Friston KJ, Malizia AL, Wilson SA et al. The analysis of dynamic radioligand displacement or activation studies. J Cerebro Blood Flow Metab 1996; In press
39. 11C-diprenorphine binding using spectral analysis of dynamic PET images acquired in 3D. In: Uemura K. (Ed) Quantification of Brain function. Amsterdam: Elsevier, 1993; 289-95
40. Myers R, Cunningham VJ, Bailey DL, Jones T. Quantification of Brain Function Using PET. New York: Academic Press, 1996; In press
41. Hietala J, Syrälahti E, Vuorio K et al. Presynaptic dopamine function in striatum of neurolepticnaive schizophrenic patients. Lancet 1995; 346: 1130-1