Effect of testosterone on binding of insulin-like growth factor-I (IGF-I) and IGF-II in growing antlers of fallow deer (Dama dama)

Growth Regulation

Volumn 6, Issue 4, 1996, Pages 214-221

  Elliott, J L ^a,b   Oldham, J M ^b   Asher, G W ^c   Molan, P C ^b   Bass, J J ^a  

^a UNIVERSITY OF WAIKATO   (New Zealand)

^b RUAKURA RESEARCH CENTRE   (New Zealand)

^c INVERMAY AGRICULTURAL CENTRE   (New Zealand)

Author keywords

Antler; Binding; IGF I; IGF II; Testosterone

Indexed keywords

SOMATOMEDIN B; SOMATOMEDIN C; TESTOSTERONE;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CARTILAGE CELL; CONTROLLED STUDY; DERMIS; EPIDERMIS; HISTOLOGY; HORMONAL REGULATION; HORN; MALE; MESENCHYME; NONHUMAN; PERICHONDRIUM; PROTEIN BINDING;

ANIMALS; ANTLERS; AUTORADIOGRAPHY; DEER; INSULIN-LIKE GROWTH FACTOR I; INSULIN-LIKE GROWTH FACTOR II; IODINE RADIOISOTOPES; MALE; RECEPTOR, IGF TYPE 2; TESTOSTERONE;

EID: 0029753734     PISSN: 0956523X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. GOSS R J. Horns and antlers. In: Principles of Regeneration. New York: Academic Press, 1969.
2. Asher G W, Day A M, Barrell G K. Annual cycle of liveweight and reproductive changes of farmed male fallow deer (Dama dama) and the effect of daily oral administration of melatonin in summer on the attainment of seasonal fertility. Reprod Fert 1987; 79: 353-362.
3. Muir P D, Sykes A R, Barrell G K. Changes in blood content and histology during growth of antlers in red deer (Cervus elaphus) and their relationship to plasma testosterone levels. Anatomy 1988; 158: 31-42.
4. Asher G W, Peterson A J, Bass J J. Seasonal pattern of LH and testosterone secretion in adult male fallow deer, Dama dama. J Reprod Fert 1989; 85: 657-665.
5. Wislocki G B, Aub J C, Waldo C M. The effects of gonadectomy and the administration of testosterone propionate on the growth of antlers in male and female deer. Endocrinology 1947; 40: 202-224.
6. Bubenik G A, Schams D, Coenen G. The effect of artificial periodicity and antiandrogen treatment on the antler growth and plasma levels of LH, FSH, testosterone, prolactin and alkaline phosphatase in the male white-tailed deer. Comp Biochem Physiol 1987; 87A: 551-559.
7. Suttie J M, Fennessy P F, Corson I D, Laas F J, Crosbie S F, Butler J H, Gluckman P D. Pulsatile growth hormone, insulin-like growth factors and antler development in red deer (Cervus elaphus scotucus) stags. J Endocrinol 1989; 121: 351-360.
8. Hobbs C J, Plymate S R, Rosen C J, Adler R A. Testosterone administration increases insulin-like growth factor-I levels in normal men. J Clin Endocrinol Metab 1993; 77: 776-779.
9. Weissberger A J, Ho K K Y. Activation of the somatotropic axis by testosterone in adult males: evidence for the role of aromatization. J Clin Endocrinol Metab 1993; 76: 1407-1412.
10. Breier B H, Gluckman P D, Bass J J. The somatotrophic axis in young steers: Influence of nutrional status and oestradiol-17β on hepatic high-and low-affinity somatotrophic binding sites. J Endocrinol 1988; 116: 169-177.
11. Kasperk C, Fitzsimmons R, Strong D, Mohan S, Jennings J, Wergedal J, Baylink D. Studies of the mechanism by which androgens enhance mitogenesis and differentiation in bone cells. J Clin Endocrinol Metab 1990; 71: 1322-1329.
12. Moore L G, Mylek M E. A novel method for the extraction of sheep insulin-like growth factors-I and -II from plasma prior to radioimmunoassay. J Endocrinol 1993; 137: 239-245.
13. Hodgkinson S C, Moore L, Napier J R, Davis S R, Bass J J, Gluckman P D. Characterisation of insulin-like growth factor binding proteins in ovine tissue fluids. J Endocrinol 1989; 120: 429-438.
14. Elliott J L, Oldham J M, Ambler G R, et al. Presence of insulin-like growth factor-I receptors and absence of growth hormone receptors in the antler tip. Endocrinology 1992; 130: 2513-2520.
15. Elliott J L, Oldham J M, Ambler G R et al. Receptors for insulin-like growth factor-II in the growing tip of the deer antler. J Endocrinol 1993; 138: 233-241.
16. Banks W J, Newbrey J W. Light microscope studies of the ossification process in developing antlers. In: Brown R D, ed. Antler Development in Cervidae. Kingsville: Caesar Kleberg Wildlife Research Institute, 1983; 231-260.
17. Ballard F J, Ross M, Upton F M, Francis G L. Specific binding of insulin-like growth factors 1 and 2 to the type 1 and type 2 receptors respectively. Biochem J 1988; 249: 721-726.
18. Chin E, Michels K, Bondy C A. Partition of insulin-like growth factor (IGF)-binding sites between the IGF-I and IGF-II receptors and IGF-binding proteins in the human kidney. J Clin Endocrinol Metab 1994; 78: 156-164.
19. Wang E, Wang J, Chin E, Zhou J, Bondy C A. Cellular patterns of insulin-like growth factor gene expression in murine chondrogenesis and osteogenesis. Endocrinology 1995; 138: 2741-2751.
20. Sadighi M, Webster J R, Suttie J M. Antler cells in testosterone treated stags. Proc Endo Soc Aus 1995; 38: NZ5.
21. Phillip M, Palese T, Hernandez E R, Roberts C T Jr, LeRoith D, Kowarski A A. Effect of testosterone on insulin-like growth factor-I (IGF-I) and IGF-I receptor gene expression in the hypophysectomized rat. Endocrinology 1992; 130: 2865-2870.
22. Williams D C, Frolik C A. Physiological and pharmacological regulation of biological calcification. Int Rev Cytol 1991; 126: 195-292.
23. Dodson M V, Allen R E, Shimizu N, Shimizu Y, Hossner K L. Interaction of ovine somatomedin and multiple stimulating activity/rat insulin-like growth factor-II with cultured skeletal muscle satellite cells. Acta Endocrinol 1983; 116: 425-432.
24. Pons S, Torres-Aleman I. Basic fibroblast growth factor modulates insulin-like growth factor-I, its receptor, and its binding proteins in hypothalamic cell cultures. Endocrinology 1992; 131: 2271-2278.
25. Bornfeldt K E, Skottner A, Arnqvist H J. In-vivo regulation of messenger RNA encoding insulin-like growth factor-I (IGF-I) and its receptor by diabetes, insulin and IGF-I in rat muscle. J Endocrinol 1992; 135: 203-211.
26. Bass J J, Whittle M A, Oldham J M, Martyn J A K, Napier J R, Hodgkinson S C. Regulation of insulin-like growth factors in plasma and insulin-like growth factor receptors by age and nutrition in sheep. Growth Reg 1994; 4: 118.
27. Kiess W, Yang Y, Kessler U, Hoeflich A. Insulin-like growth factor II (IGF-II) and the IGF-II/mannose-6-phosphate receptor: the myth continues. Horm Res 1994; 41: 66-73.
28. Rosenthal S M, Brown E J. Mechanisms of insulin-like growth factor (IGF)-II-induced IGF-I receptor down-regulation in BC3H-1 muscle cells. J Endocrinol 1994; 141: 69-74.
29. Humbel R E. Insulin-like growth factors I and II. Eur J Biochem 1990; 190: 445-462.
30. Mohan S, Baylink D J. The role of insulin-like growth factor-II in the coupling of bone formation to resorption. In: Spencer E M, ed. Modern Concepts of Insulin-like Growth Factors. New York: Elsevier, 1991; 169-184.
31. Morris J M, Bubenik G A. The effects of androgens on the development of antler bone. In: Brown R D, ed. Antler Development in Cervidae. Kingsville: Caesar Kleberg Wildlife Research Institute, 1983; 123-141.
32. Lewis L K, Barrell G K. Localisation of oestradiol receptors in antler tissue. Proc Endo Soc Aus 1991; 34: NZ5.