Analogues of capsaicin with agonist activity as novel analgesic agents: Structure-activity studies. 4. Potent, orally active analgesics

Journal of Medicinal Chemistry

Volumn 39, Issue 25, 1996, Pages 4942-4951

  Wrigglesworth, Roger ^a   Walpole, Christopher S J ^a   Bevan, Stuart ^a   Campbell, Elizabeth A ^a   Dray, Andy ^a   Hughes, Glyn A ^a   James, Iain ^a   Masdin, Kay J ^a   Winter, Janet ^a  

^a Sandoz Institute for Medical Research   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANALGESIC AGENT; CAPSAICIN DERIVATIVE; NUVANIL; OLVANIL;

AGONIST; ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BRONCHOSPASM; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG GLUCURONIDATION; DRUG METABOLISM; DRUG POTENCY; FEMALE; GUINEA PIG; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STRUCTURE ACTIVITY RELATION; SUBCUTANEOUS DRUG ADMINISTRATION; TAIL FLICK TEST; WRITHING TEST;

ADMINISTRATION, ORAL; ANALGESICS; ANIMALS; CAPSAICIN; FEMALE; GUINEA PIGS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0029752039     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960512h     Document Type: Article

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