Survival analyses of randomized clinical trials adjusted for patients who switch treatments

Statistics in Medicine

Volumn 15, Issue 19, 1996, Pages 2069-2076

  Law, Matthew G ^a   Kaldor, John M ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLADDER CANCER; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; CYSTECTOMY; DATA ANALYSIS; HUMAN; RELIABILITY; STATISTICAL ANALYSIS;

CONFIDENCE INTERVALS; CROSS-OVER STUDIES; CYSTECTOMY; HUMANS; PROPORTIONAL HAZARDS MODELS; RADIOTHERAPY DOSAGE; RANDOMIZED CONTROLLED TRIALS; REGRESSION ANALYSIS; SURVIVAL ANALYSIS; URINARY BLADDER NEOPLASMS;

EID: 0029747282     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0258(19961015)15:19<2069::AID-SIM347>3.0.CO;2-V     Document Type: Article

References (9)

1. Peto, R., Pike, M. C., Armitage, P., Breslow, N. E., Cox, D. R., Howard, S. V., Mantel, N., McPherson, K., Peto, J. and Smith, P. G. 'Design and analysis of randomised controlled trials requiring prolonged observation of each patient. I. Introduction and design', British Journal of Cancer, 34, 585-612 (1976).
2. May, G. S., DeMets, D. L., Freidman, L. M., Furberg, C. and Passamani, E. 'The randomised clinical trial: bias in analysis', Circulation, 64, 669-673 (1981).
3. Lee, Y. J., Ellenberg, J. H., Hirtz, D. G. and Nelson, K. B. 'Analysis of clinical trials by treatment received: is it really an option?', Statistics in Medicine, 10, 1595-1605 (1991).
4. Peduzzi, P., Wittes, J., Detre, K. and Holford, T. 'Analysis as-randomized and the problems of non-adherence: an example from the veterans affairs randomized trial of coronary artery bypass surgery', Statistics in Medicine, 12, 1185-1195 (1993).
5. Newcombe, R. G. 'Explanatory and pragmatic estimates of the treatment effect when deviations from allocated treatment occur', Statistics in Medicine, 7, 1179-1186 (1988).
6. Cox, D. R. and Oakes, D. Analysis of Survival Data, Chapman and Hall, London, 1984.
7. Bloom, H. J. G., Hendry, W. F., Wallace, D. M. and Skeet, R. G. 'Treatment of T3 bladder cancer: controlled trial of preoperative radiotherapy and radical cystectomy versus radical radiotherapy', British Journal of Urology, 54, 136-151 (1982).
8. Horwich, A., Law, M. G. on behalf of the Cooperative Urological Cancer Group (CUCG). 'Final analysis of two prospective randomised trials in T3 bladder cancer', British Journal of Cancer, 70 (supplement XXII), 15 (1994) (abstract).
9. SERC. EGRET Reference Manual: Revision 4, Statistics and Epidemiology Research Corporation, Seattle, 1993.