메뉴 건너뛰기




Volumn 71, Issue 1-2, 1996, Pages 107-126

Benzidine mechanistic data and risk assessment: Species- and organ-specific metabolic activation

Author keywords

aromatic amines; benzidine; DNA adducts; genotoxicity; neoplasia; risk assessment

Indexed keywords

BENZIDINE;

EID: 0029747155     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/0163-7258(96)00064-2     Document Type: Review
Times cited : (56)

References (146)
  • 1
    • 0000179727 scopus 로고
    • Carcinogens are mutagens: A simple test system combining liver homogenates for activation and bacteria for detection
    • Ames, B. N., Durston, W. E., Yamasaki, E. and Lee, F. D. (1973) Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection. Proc. Natl. Acad. Sci. USA 70: 2281-2285.
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 2281-2285
    • Ames, B.N.1    Durston, W.E.2    Yamasaki, E.3    Lee, F.D.4
  • 2
    • 0017979814 scopus 로고
    • The bacterial mutation test
    • Anderson, D. and Styles, J. A. (1978) The bacterial mutation test. Br. J. Cancer 37: 924-930.
    • (1978) Br. J. Cancer , vol.37 , pp. 924-930
    • Anderson, D.1    Styles, J.A.2
  • 3
    • 0020674556 scopus 로고
    • Activation of mammalian carcinogens to bacterial mutagens by microsomal enzymes from a pelecypod mollusk, Mercenaria mercenaria
    • Anderson, R. S. and Döös, J. E. (1983) Activation of mammalian carcinogens to bacterial mutagens by microsomal enzymes from a pelecypod mollusk, Mercenaria mercenaria. Mutat. Res. 116: 247-256.
    • (1983) Mutat. Res. , vol.116 , pp. 247-256
    • Anderson, R.S.1    Döös, J.E.2
  • 4
    • 0020287534 scopus 로고
    • Differential ability of Ambystoma tigrinum hepatic microsomes to produce mutagenic metabolites from polycyclic aromatic hydrocarbons and aromatic amines
    • Anderson, R. S., Döös, J. E. and Rose, F. L. (1982) Differential ability of Ambystoma tigrinum hepatic microsomes to produce mutagenic metabolites from polycyclic aromatic hydrocarbons and aromatic amines. Cancer Lett. 16: 33-41.
    • (1982) Cancer Lett. , vol.16 , pp. 33-41
    • Anderson, R.S.1    Döös, J.E.2    Rose, F.L.3
  • 5
    • 0020364913 scopus 로고
    • Evaluation of two suggested methods of deactivating organic carcinogens by molecular modification
    • Ashby, J., Paton, D., Lefevre, P. A. and Styles, J. A. (1982) Evaluation of two suggested methods of deactivating organic carcinogens by molecular modification. Carcinogenesis 3: 1277-1282.
    • (1982) Carcinogenesis , vol.3 , pp. 1277-1282
    • Ashby, J.1    Paton, D.2    Lefevre, P.A.3    Styles, J.A.4
  • 6
    • 0026637260 scopus 로고
    • Role of N-glucuronidation in benzidine-induced bladder cancer in dog
    • Babu, S. R., Lakshmi, V. M., Hsu, F. F., Zenser, T. V. and Davis, B. B. (1992) Role of N-glucuronidation in benzidine-induced bladder cancer in dog. Carcinogenesis 13: 1235-1240.
    • (1992) Carcinogenesis , vol.13 , pp. 1235-1240
    • Babu, S.R.1    Lakshmi, V.M.2    Hsu, F.F.3    Zenser, T.V.4    Davis, B.B.5
  • 8
    • 0020335340 scopus 로고
    • Morphological classification of mouse liver tumors based on biological characteristics
    • Becker, F. F. (1982) Morphological classification of mouse liver tumors based on biological characteristics. Cancer Res. 42: 3918-3923.
    • (1982) Cancer Res. , vol.42 , pp. 3918-3923
    • Becker, F.F.1
  • 9
    • 0023093771 scopus 로고
    • Induction of unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats exposed in vivo to the benzidine-derived azo dye, Direct Black 38
    • Beije, B. (1987) Induction of unscheduled DNA synthesis in liver and micronucleus in bone marrow of rats exposed in vivo to the benzidine-derived azo dye, Direct Black 38. Mutat. Res. 187: 227-234.
    • (1987) Mutat. Res. , vol.187 , pp. 227-234
    • Beije, B.1
  • 10
    • 0022273489 scopus 로고
    • Formation and persistence of arylamine DNA adducts in vivo
    • Beland, F. A. and Kadlubar, F. F. (1985) Formation and persistence of arylamine DNA adducts in vivo. Environ. Health Perspect. 62: 19-30.
    • (1985) Environ. Health Perspect. , vol.62 , pp. 19-30
    • Beland, F.A.1    Kadlubar, F.F.2
  • 11
    • 0000037422 scopus 로고
    • Metabolic activation and DNA adducts of aromatic amines and nitroaromatic hydrocarbons
    • Cooper, C. S. and Grover, P. L. (eds.) Springer-Verlag, Berlin
    • Beland, F. A. and Kadlubar, F. F. (1990) Metabolic activation and DNA adducts of aromatic amines and nitroaromatic hydrocarbons. In: Handbook of Experimental Pharmacology, pp. 267-325, Cooper, C. S. and Grover, P. L. (eds.) Springer-Verlag, Berlin.
    • (1990) Handbook of Experimental Pharmacology , pp. 267-325
    • Beland, F.A.1    Kadlubar, F.F.2
  • 12
    • 0020972626 scopus 로고
    • Arylamine-DNA adducts in vitro and in vivo: Their role in bacterial mutagenesis and urinary bladder carcinogenesis
    • Beland, F. A., Beranek, D. T., Dooley, K. L., Heflich, R. H. and Kadlubar, F. F. (1983) Arylamine-DNA adducts in vitro and in vivo: their role in bacterial mutagenesis and urinary bladder carcinogenesis. Environ. Health Perspect. 49: 125-134.
    • (1983) Environ. Health Perspect. , vol.49 , pp. 125-134
    • Beland, F.A.1    Beranek, D.T.2    Dooley, K.L.3    Heflich, R.H.4    Kadlubar, F.F.5
  • 15
    • 0019455605 scopus 로고
    • Evaluation of DNA damage by alkaline elution technique after in vivo treatment with aromatic amines
    • Bolognesi, C., Cesarone, C. F. and Santi, L. (1981) Evaluation of DNA damage by alkaline elution technique after in vivo treatment with aromatic amines. Carcinogenesis 2: 265-268.
    • (1981) Carcinogenesis , vol.2 , pp. 265-268
    • Bolognesi, C.1    Cesarone, C.F.2    Santi, L.3
  • 16
    • 84966418359 scopus 로고
    • Test for carcinogenic aromatic amines
    • Bonser, G. M. (1959) Test for carcinogenic aromatic amines. J. Rep. Br. Emp. Cancer Camp. 37: 417-421.
    • (1959) J. Rep. Br. Emp. Cancer Camp. , vol.37 , pp. 417-421
    • Bonser, G.M.1
  • 17
    • 0011785366 scopus 로고
    • The induction of tumours of the subcutaneous tissues, liver and intestine in the mouse by certain dye-stuffs and their intermediates
    • Bonser, G. M., Clayson, D. B. and Jull, J. W. (1956) The induction of tumours of the subcutaneous tissues, liver and intestine in the mouse by certain dye-stuffs and their intermediates. Br. J. Cancer 10: 653-667.
    • (1956) Br. J. Cancer , vol.10 , pp. 653-667
    • Bonser, G.M.1    Clayson, D.B.2    Jull, J.W.3
  • 18
    • 0020051288 scopus 로고
    • Comparison of the mutagenicities of 4-aminobiphenyl and benzidine in the Salmonella/microsome, Salmonella/hepatocyte and host-mediated assays
    • Bos, R. P., van Doorn, R., Yih-van de Hurk, E., Van Gemert, P. J. L. and Henderson, P. T. (1982) Comparison of the mutagenicities of 4-aminobiphenyl and benzidine in the Salmonella/microsome, Salmonella/hepatocyte and host-mediated assays. Mutat. Res. 93: 317-325.
    • (1982) Mutat. Res. , vol.93 , pp. 317-325
    • Bos, R.P.1    Van Doorn, R.2    Yih-Van De Hurk, E.3    Van Gemert, P.J.L.4    Henderson, P.T.5
  • 19
    • 0021090106 scopus 로고
    • Mutagenicity testing with the Salmonella/hepatocyte and the Salmonella/microsome assays
    • Bos, R. P., Neis, J. M., van Gemert, P. J. L. and Henderson, P. T. (1983) Mutagenicity testing with the Salmonella/hepatocyte and the Salmonella/microsome assays. Mutat. Res. 124: 103-112.
    • (1983) Mutat. Res. , vol.124 , pp. 103-112
    • Bos, R.P.1    Neis, J.M.2    Van Gemert, P.J.L.A.3    Henderson, P.T.4
  • 20
    • 0011794107 scopus 로고
    • The induction of carcinoma of the bladder in rats with acetamidofluorene
    • Boyland, E., Harris, J. and Horning, E. S. (1954) The induction of carcinoma of the bladder in rats with acetamidofluorene. Br. J. Cancer 8: 647-654.
    • (1954) Br. J. Cancer , vol.8 , pp. 647-654
    • Boyland, E.1    Harris, J.2    Horning, E.S.3
  • 21
    • 0018642957 scopus 로고
    • Measurement of DNA-excision repair in suspensions of freshly isolated rat hepatocytes after exposure to some carcinogenic compounds. Its possible use in carcinogenicity screening
    • Brouns, R. E., Poot, M., de Vrind, R., Hoek-Kon, T. V. and Henderson, P. T. (1979) Measurement of DNA-excision repair in suspensions of freshly isolated rat hepatocytes after exposure to some carcinogenic compounds. Its possible use in carcinogenicity screening. Mutat. Res. 64: 425-432.
    • (1979) Mutat. Res. , vol.64 , pp. 425-432
    • Brouns, R.E.1    Poot, M.2    De Vrind, R.3    Hoek-Kon, T.V.4    Henderson, P.T.5
  • 22
    • 0019952413 scopus 로고
    • Studies on the metabolic activaction of benzidine by isolated rat hepatocytes
    • Brouns, R. M. E., Bos, R. P., Van Doorn, R. and Henderson, P. T. (1982) Studies on the metabolic activaction of benzidine by isolated rat hepatocytes. Toxicology 23: 235-247.
    • (1982) Toxicology , vol.23 , pp. 235-247
    • Brouns, R.M.E.1    Bos, R.P.2    Van Doorn, R.3    Henderson, P.T.4
  • 23
    • 0020665576 scopus 로고
    • Mutagenicity of selected sulfonated azo dyes in the Salmonella/microsome assay: Use of aerobic and anaerobic activation procedures
    • Brown, J. P. and Dietrich, P. S. (1983) Mutagenicity of selected sulfonated azo dyes in the Salmonella/microsome assay: use of aerobic and anaerobic activation procedures. Mutat. Res. 116: 305-315.
    • (1983) Mutat. Res. , vol.116 , pp. 305-315
    • Brown, J.P.1    Dietrich, P.S.2
  • 24
    • 0017851261 scopus 로고
    • Mutagenicity testing of certified food colors and related azo, xanthene and triphenylmethane dyes with the Salmonella/microsome system
    • Brown, J. P., Roehm, G. W. and Brown, R. J. (1978) Mutagenicity testing of certified food colors and related azo, xanthene and triphenylmethane dyes with the Salmonella/microsome system. Mutat. Res. 56: 249-271.
    • (1978) Mutat. Res. , vol.56 , pp. 249-271
    • Brown, J.P.1    Roehm, G.W.2    Brown, R.J.3
  • 25
    • 0023433842 scopus 로고
    • Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters
    • Büsser, M. T. and Lutz, W. K. (1987) Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters. Carcinogenesis 8: 1433-1437.
    • (1987) Carcinogenesis , vol.8 , pp. 1433-1437
    • Büsser, M.T.1    Lutz, W.K.2
  • 26
    • 0019976311 scopus 로고
    • Role of N-acetyltransferase phenotypes in bladder carcinogenesis: A pharmacogenetic epidemiological approach to bladder cancer
    • Cartwright, R. A., Glashan, R. W., Rogers, H. J., Ahmad, R. A., Barham-Hall, D., Higgins, E. and Kahn, M. A. (1982) Role of N-acetyltransferase phenotypes in bladder carcinogenesis: a pharmacogenetic epidemiological approach to bladder cancer. Lancet ii: 842-845.
    • (1982) Lancet , vol.2 , pp. 842-845
    • Cartwright, R.A.1    Glashan, R.W.2    Rogers, H.J.3    Ahmad, R.A.4    Barham-Hall, D.5    Higgins, E.6    Kahn, M.A.7
  • 27
    • 0345253889 scopus 로고
    • Mutation induction at multiple gene loci in Chinese hamster ovary cells: Genetic activity of 15 coded carcinogens and noncarcinogens
    • Carver, J. H., Salazar, E. P., Knize, M. G. and Wandres, D. L. (1981) Mutation induction at multiple gene loci in Chinese hamster ovary cells: genetic activity of 15 coded carcinogens and noncarcinogens. Prog. Mutat. Res. 1: 594-601.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 594-601
    • Carver, J.H.1    Salazar, E.P.2    Knize, M.G.3    Wandres, D.L.4
  • 28
    • 0003033767 scopus 로고
    • Tumours of the urinary bladder in workmen engaged in the manufacture and use of certain dyestuff intermediates in the British chemical industry
    • Case, R. A. M., Hosker, M. E., McDonald, D. B. and Pearson, J. T. (1954) Tumours of the urinary bladder in workmen engaged in the manufacture and use of certain dyestuff intermediates in the British chemical industry. Br. J. Ind. Med. 11: 75-104.
    • (1954) Br. J. Ind. Med. , vol.11 , pp. 75-104
    • Case, R.A.M.1    Hosker, M.E.2    McDonald, D.B.3    Pearson, J.T.4
  • 29
    • 0020323957 scopus 로고
    • Evaluation of damage to DNA after in vivo exposure to different classes of chemicals
    • Cesarone, C. F., Bolognesi, C. and Santi, L. (1982) Evaluation of damage to DNA after in vivo exposure to different classes of chemicals. Arch. Toxicol. 5 (Suppl.): 355-359.
    • (1982) Arch. Toxicol. , vol.5 , Issue.SUPPL. , pp. 355-359
    • Cesarone, C.F.1    Bolognesi, C.2    Santi, L.3
  • 30
    • 0018406781 scopus 로고
    • Evaluation of benzidine by the micronucleus test
    • Čihák, R. (1979) Evaluation of benzidine by the micronucleus test. Mutat. Res. 67: 383-384.
    • (1979) Mutat. Res. , vol.67 , pp. 383-384
    • Čihák, R.1
  • 31
    • 0025158299 scopus 로고
    • Microwell mutation assays: Evaluation of ethylmethanesulphonate, benzo[a]pyrene and benzidine using the tk locus in L5178Y mouse lymphoma cells
    • Clay, P. and Cross, M. F. (1990) Microwell mutation assays: evaluation of ethylmethanesulphonate, benzo[a]pyrene and benzidine using the tk locus in L5178Y mouse lymphoma cells. Mutagenesis 5: 45-54.
    • (1990) Mutagenesis , vol.5 , pp. 45-54
    • Clay, P.1    Cross, M.F.2
  • 33
    • 0018279117 scopus 로고
    • Investigation of mutagenic effects of products of ozonation reactions in water
    • Cotruvo, J. A., Simmon, V. F. and Spanggord, R. J. (1977) Investigation of mutagenic effects of products of ozonation reactions in water. Ann. NY Acad. Sci. 298: 124-140.
    • (1977) Ann. NY Acad. Sci. , vol.298 , pp. 124-140
    • Cotruvo, J.A.1    Simmon, V.F.2    Spanggord, R.J.3
  • 34
    • 0026096161 scopus 로고
    • A metabolically competent human cell line expressing five CDNAS encoding procarcinogen-activating enzymes: Application to mutagenicity testing
    • Crespi, C. L., Gonzalez, F. J., Steimel, D. T., Turner, T. R., Gelboin, H. V., Penman, B. W. and Langenbach, R. (1991) A metabolically competent human cell line expressing five CDNAS encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chem. Res. Toxicol. 4: 566-572.
    • (1991) Chem. Res. Toxicol. , vol.4 , pp. 566-572
    • Crespi, C.L.1    Gonzalez, F.J.2    Steimel, D.T.3    Turner, T.R.4    Gelboin, H.V.5    Penman, B.W.6    Langenbach, R.7
  • 35
    • 0017661844 scopus 로고
    • Confidence intervals and test of hypotheses concerning dose-response relations inferred from animal carcinogenicity data
    • Crump, K. S., Guess, H. A. and Deal, K. L. (1977) Confidence intervals and test of hypotheses concerning dose-response relations inferred from animal carcinogenicity data. Biometrics 22: 437-451.
    • (1977) Biometrics , vol.22 , pp. 437-451
    • Crump, K.S.1    Guess, H.A.2    Deal, K.L.3
  • 37
    • 85030278473 scopus 로고
    • EPA/600/8-89/043
    • Environmental Protection Agency (EPA) (1989) Exposure Factors Handhook. EPA/600/8-89/043.
    • (1989) Exposure Factors Handhook
  • 38
    • 26444539817 scopus 로고
    • Genetic control of isoniazid metabolism in man
    • Evans, D. A. P., Manley, K. A. and Mukusick, V. A. (1960) Genetic control of isoniazid metabolism in man. Br. Med. J. 2: 485-491.
    • (1960) Br. Med. J. , vol.2 , pp. 485-491
    • Evans, D.A.P.1    Manley, K.A.2    Mukusick, V.A.3
  • 39
    • 0001345867 scopus 로고
    • Effects of 20 coded chemicals on sister chromatid exchange frequencies in cultured Chinese hamster cells
    • Evans, E. L. and Mitchell, A. D. (1981) Effects of 20 coded chemicals on sister chromatid exchange frequencies in cultured Chinese hamster cells. Prog. Mutat. Res. 1: 538-550.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 538-550
    • Evans, E.L.1    Mitchell, A.D.2
  • 40
    • 0017737640 scopus 로고
    • Mutagenicity of benzidine and related compounds employed in the detection of hemoglobin
    • Ferretti, J. J., Lu, W. and Liu, M. B. (1977) Mutagenicity of benzidine and related compounds employed in the detection of hemoglobin. Am. J. Pathol. 67: 526-527.
    • (1977) Am. J. Pathol. , vol.67 , pp. 526-527
    • Ferretti, J.J.1    Lu, W.2    Liu, M.B.3
  • 41
    • 0024538978 scopus 로고
    • Arachidonic acid-dependent peroxidative activation of carcinogenic arylamines by extrahepatic human tissue microsomes
    • Flammang, T. J., Yamazoe, Y., Benson, R. W., Roberts, D. W., Potter, D. W., Chu, D. Z. J., Lang, N. P. and Kadlubar, F. F. (1989) Arachidonic acid-dependent peroxidative activation of carcinogenic arylamines by extrahepatic human tissue microsomes. Cancer Res. 49: 1977-1982.
    • (1989) Cancer Res. , vol.49 , pp. 1977-1982
    • Flammang, T.J.1    Yamazoe, Y.2    Benson, R.W.3    Roberts, D.W.4    Potter, D.W.5    Chu, D.Z.J.6    Lang, N.P.7    Kadlubar, F.F.8
  • 43
    • 0021868587 scopus 로고
    • Hepatic N-oxidation, acetyl-transfer and DNA-binding of the acetylated metabolites of the carcinogen, benzidine
    • Frederick, C. B., Weis, C. C., Flammang, T. J., Martin, C. N. and Kadlubar, F. F. (1985) Hepatic N-oxidation, acetyl-transfer and DNA-binding of the acetylated metabolites of the carcinogen, benzidine. Carcinogenesis 6: 959-965.
    • (1985) Carcinogenesis , vol.6 , pp. 959-965
    • Frederick, C.B.1    Weis, C.C.2    Flammang, T.J.3    Martin, C.N.4    Kadlubar, F.F.5
  • 44
    • 0017234761 scopus 로고
    • Brief communication: Hepatic cytologic and neoplastic changes in mice given benzidine dihydrochloride
    • Frith, C. H. and Dooley, K. (1976) Brief communication: hepatic cytologic and neoplastic changes in mice given benzidine dihydrochloride. J. Natl. Cancer Inst. 56: 679-682.
    • (1976) J. Natl. Cancer Inst. , vol.56 , pp. 679-682
    • Frith, C.H.1    Dooley, K.2
  • 45
    • 0000844210 scopus 로고
    • Investigation of the genetic control of sulfadiazene and isoniazid metabolism in the rabbit
    • Frymoyer, J. W. and Jacox, R. F. (1963a) Investigation of the genetic control of sulfadiazene and isoniazid metabolism in the rabbit. J. Lab. Clin. Med. 62: 891-904.
    • (1963) J. Lab. Clin. Med. , vol.62 , pp. 891-904
    • Frymoyer, J.W.1    Jacox, R.F.2
  • 46
    • 0000782121 scopus 로고
    • Studies of genetically controlled sulfadiazine acetylation in rabbit livers: Possible identification of the heterozygous trait
    • Frymoyer, J. W. and Jacox, R. F. (1963b) Studies of genetically controlled sulfadiazine acetylation in rabbit livers: possible identification of the heterozygous trait. J. Lab. Clin. Med. 62: 905-909.
    • (1963) J. Lab. Clin. Med. , vol.62 , pp. 905-909
    • Frymoyer, J.W.1    Jacox, R.F.2
  • 47
    • 0016688410 scopus 로고
    • Testing of some benzidine analogues for microsomal activation to bacterial mutagens
    • Garner, R. C., Walpole, A. L. and Rose, F. L. (1975) Testing of some benzidine analogues for microsomal activation to bacterial mutagens. Cancer Lett. 1: 39-42.
    • (1975) Cancer Lett. , vol.1 , pp. 39-42
    • Garner, R.C.1    Walpole, A.L.2    Rose, F.L.3
  • 48
    • 0019298495 scopus 로고
    • Linear interpolation algorithm for low dose risk assessment of toxic substances
    • Gaylor, D. W. and Kodell, R. L. (1980) Linear interpolation algorithm for low dose risk assessment of toxic substances. J. Environ. Pathol. Toxicol. 4: 305-312.
    • (1980) J. Environ. Pathol. Toxicol. , vol.4 , pp. 305-312
    • Gaylor, D.W.1    Kodell, R.L.2
  • 49
    • 0017326412 scopus 로고
    • Formation of blastomogenic diphenylamino derivatives as a result of the metabolism of direct azo dyes
    • Genin, V. A. (1977) Formation of blastomogenic diphenylamino derivatives as a result of the metabolism of direct azo dyes. Vopr. Onkol. 23: 50-52.
    • (1977) Vopr. Onkol. , vol.23 , pp. 50-52
    • Genin, V.A.1
  • 50
    • 0018092881 scopus 로고
    • Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver
    • Glowinski, I. B., Radtke, H. E. and Weber, W. W. (1978) Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver. Mol. Pharmacol. 14: 940-949.
    • (1978) Mol. Pharmacol. , vol.14 , pp. 940-949
    • Glowinski, I.B.1    Radtke, H.E.2    Weber, W.W.3
  • 52
    • 0015596820 scopus 로고
    • Polymorphic acetylation of drugs in rabbits
    • Gordon, G. R., Shafizadek, A. G. and Peters, J. H. (1973) Polymorphic acetylation of drugs in rabbits. Xenobiotica 3: 133-150.
    • (1973) Xenobiotica , vol.3 , pp. 133-150
    • Gordon, G.R.1    Shafizadek, A.G.2    Peters, J.H.3
  • 53
    • 0022877269 scopus 로고
    • Induction of sister chromatid exchanges by benzidine in rat and human hepatoma cell lines and inhibition by indomethacin
    • Grady, M. K., Jacobson-Kram, D., Dearfield, K. L. and Williams, J. R. (1986) Induction of sister chromatid exchanges by benzidine in rat and human hepatoma cell lines and inhibition by indomethacin. Cell Biol. Toxicol. 2: 223-230.
    • (1986) Cell Biol. Toxicol. , vol.2 , pp. 223-230
    • Grady, M.K.1    Jacobson-Kram, D.2    Dearfield, K.L.3    Williams, J.R.4
  • 54
    • 0021675377 scopus 로고
    • The carcinogenic potential of benzidine-based dyes
    • Gregory, A. R. (1984) The carcinogenic potential of benzidine-based dyes. J. Environ. Pathol. Toxicol. Oncol. 5: 243-259.
    • (1984) J. Environ. Pathol. Toxicol. Oncol. , vol.5 , pp. 243-259
    • Gregory, A.R.1
  • 55
    • 0019692736 scopus 로고
    • Ames testing of Direct Black 38 parallels carcinogenicity testing
    • Gregory, A. R., Elliott, J. and Kluge, P. (1981) Ames testing of Direct Black 38 parallels carcinogenicity testing. J. Appl. Toxicol. 1: 308-313.
    • (1981) J. Appl. Toxicol. , vol.1 , pp. 308-313
    • Gregory, A.R.1    Elliott, J.2    Kluge, P.3
  • 56
    • 0014290322 scopus 로고
    • The carcinogenicity of multiple intragastric doses of aromatic and heterocyclic nitro or amino derivatives in young female Sprague-Dawley rats
    • Griswold, D. P., Casey, A. E., Weisburger, E. K. and Weisburger, J. H. (1968) The carcinogenicity of multiple intragastric doses of aromatic and heterocyclic nitro or amino derivatives in young female Sprague-Dawley rats. Cancer Res. 28: 924-933.
    • (1968) Cancer Res. , vol.28 , pp. 924-933
    • Griswold, D.P.1    Casey, A.E.2    Weisburger, E.K.3    Weisburger, J.H.4
  • 58
    • 0019969638 scopus 로고
    • Mutagenic responses of five independent genetic loci in CHO cells to a variety of mutagens. Development and characteristics of a mutagen screening system based on selection for multiple drug-resistant markers
    • Gupta, R. S. and Singh, B. (1982) Mutagenic responses of five independent genetic loci in CHO cells to a variety of mutagens. Development and characteristics of a mutagen screening system based on selection for multiple drug-resistant markers. Mutat. Res. 94: 449-466.
    • (1982) Mutat. Res. , vol.94 , pp. 449-466
    • Gupta, R.S.1    Singh, B.2
  • 59
    • 0024997081 scopus 로고
    • Acetylation phenotypes and bladder cancer
    • Hanke, J. and Krajewska, B. (1990) Acetylation phenotypes and bladder cancer. J. Occup. Med. 32: 917-918.
    • (1990) J. Occup. Med. , vol.32 , pp. 917-918
    • Hanke, J.1    Krajewska, B.2
  • 61
    • 0016442277 scopus 로고
    • Alkaline phosphatase activity in hyperplastic and neoplastic urinary bladder epithelium of mice fed 2-acetylaminofluorene
    • Highman, B., Frith, C. H. and Littlefield, N. A. (1975) Alkaline phosphatase activity in hyperplastic and neoplastic urinary bladder epithelium of mice fed 2-acetylaminofluorene. J. Natl. Cancer Inst. 54: 257-261.
    • (1975) J. Natl. Cancer Inst. , vol.54 , pp. 257-261
    • Highman, B.1    Frith, C.H.2    Littlefield, N.A.3
  • 62
    • 0023231469 scopus 로고
    • Comparative activation of 3,3′-dichlorobenzidine and related benzidines to mutagens in the Salmonella typhimurium assay by hepatic S9 and microsomes from rats pretreated with different inducers of cytochrome P-450
    • Iba, M. M. (1987) Comparative activation of 3,3′-dichlorobenzidine and related benzidines to mutagens in the Salmonella typhimurium assay by hepatic S9 and microsomes from rats pretreated with different inducers of cytochrome P-450. Mutat. Res. 182: 231-241.
    • (1987) Mutat. Res. , vol.182 , pp. 231-241
    • Iba, M.M.1
  • 63
    • 0011739655 scopus 로고
    • Benzidine
    • International Agency for Research on Cancer (IARC) (1987) Benzidine. IARC Monogr. (Suppl. 7): 123-126.
    • (1987) IARC Monogr. , Issue.SUPPL. 7 , pp. 123-126
  • 64
    • 0000014016 scopus 로고
    • Effects of 20 coded chemicals on the forward mutation frequency at the thymidine kinase locus in L5178Y mouse lymphoma cells
    • Jotz, M. M. and Mitchell, A. D. (1981) Effects of 20 coded chemicals on the forward mutation frequency at the thymidine kinase locus in L5178Y mouse lymphoma cells. Prog. Mutat. Res. 1: 580-593.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 580-593
    • Jotz, M.M.1    Mitchell, A.D.2
  • 65
    • 0022487593 scopus 로고
    • Carcinogen-DNA adduct formation as a predictor of metabolic activation pathways and reactive intermediates in benzidine carcinogenesis
    • Kadlubar, F. F., Yamazoe, Y., Lang, N. P., Chu, D. Z. J. and Beland, F. A. (1986) Carcinogen-DNA adduct formation as a predictor of metabolic activation pathways and reactive intermediates in benzidine carcinogenesis. Adv. Exp. Med. Biol. 197: 537-549.
    • (1986) Adv. Exp. Med. Biol. , vol.197 , pp. 537-549
    • Kadlubar, F.F.1    Yamazoe, Y.2    Lang, N.P.3    Chu, D.Z.J.4    Beland, F.A.5
  • 66
    • 0021352586 scopus 로고
    • Binding of N-acetylbenzidine and N,N'-diacetylbenzidine to hepatic DNA of rat and hamster in vivo and in vitro
    • Kennelly, J. C., Beland, F. A., Kadlubar, F. F. and Martin, C. N. (1984) Binding of N-acetylbenzidine and N,N'-diacetylbenzidine to hepatic DNA of rat and hamster in vivo and in vitro. Carcinogenesis 5: 407-412.
    • (1984) Carcinogenesis , vol.5 , pp. 407-412
    • Kennelly, J.C.1    Beland, F.A.2    Kadlubar, F.F.3    Martin, C.N.4
  • 67
    • 0025123033 scopus 로고
    • The mutagenic activity of ethylmethanesulphonate, benzidine and benzo[a]pyrene at the hprt locus of wild-type L5178Y mouse lymphoma cells
    • Kennelly, J. C., Clare, C. B., Campbell, J., Lane, M. P., Harrington, D. H., Cole, H. and Garner, R. C. (1990) The mutagenic activity of ethylmethanesulphonate, benzidine and benzo[a]pyrene at the hprt locus of wild-type L5178Y mouse lymphoma cells. Mutagenesis 5: 21-26.
    • (1990) Mutagenesis , vol.5 , pp. 21-26
    • Kennelly, J.C.1    Clare, C.B.2    Campbell, J.3    Lane, M.P.4    Harrington, D.H.5    Cole, H.6    Garner, R.C.7
  • 68
    • 0344374487 scopus 로고
    • Mutagenic activity of 7 coded samples in V79 Chinese hamster cells
    • Knaap, A. G. A. C., Goze, C. and Simons, J. W. I. M. (1981) Mutagenic activity of 7 coded samples in V79 Chinese hamster cells. Prog. Mutat. Res. 1: 608-613.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 608-613
    • Knaap, A.G.A.C.1    Goze, C.2    Simons, J.W.I.M.3
  • 69
    • 0021240430 scopus 로고
    • Comparison of 7 azo dyes and their azo reduction products in the rat and hamster hepatocyte primary culture/DNA-repair assays
    • Kornbrust, D. J. and Barfknecht, T. R. (1984) Comparison of 7 azo dyes and their azo reduction products in the rat and hamster hepatocyte primary culture/DNA-repair assays. Mutat. Res. 136: 255-266.
    • (1984) Mutat. Res. , vol.136 , pp. 255-266
    • Kornbrust, D.J.1    Barfknecht, T.R.2
  • 71
    • 0018386164 scopus 로고
    • Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides and disulfides
    • Lavoie, E., Tulley, L., Fow, E. and Hoffmann, D. (1979) Mutagenicity of aminophenyl and nitrophenyl ethers, sulfides and disulfides. Mutat. Res. 67: 123-131.
    • (1979) Mutat. Res. , vol.67 , pp. 123-131
    • Lavoie, E.1    Tulley, L.2    Fow, E.3    Hoffmann, D.4
  • 72
    • 0017835481 scopus 로고
    • Mutagenicity of some congeners of benzidine in the Salmonella typhimurium assay system
    • Lazear, E. J. and Louie, S. C. (1977) Mutagenicity of some congeners of benzidine in the Salmonella typhimurium assay system. Cancer Lett. 4: 21-25.
    • (1977) Cancer Lett. , vol.4 , pp. 21-25
    • Lazear, E.J.1    Louie, S.C.2
  • 73
    • 0021088066 scopus 로고
    • Benzidine dihydrochloride: Toxicological assessment in mice during chronic exposures
    • Littlefield, N. A., Nelson, C. J. and Frith, C. H. (1983) Benzidine dihydrochloride: toxicological assessment in mice during chronic exposures. J. Toxicol. Environ. Health 12: 671-685.
    • (1983) J. Toxicol. Environ. Health , vol.12 , pp. 671-685
    • Littlefield, N.A.1    Nelson, C.J.2    Frith, C.H.3
  • 75
    • 0015893308 scopus 로고
    • Enzymatic N-acetylation of carcinogenic aromatic amines by liver cytosol of species displaying different organ susceptibilities
    • Lower, G. M., Jr. and Bryan, G. T. (1973) Enzymatic N-acetylation of carcinogenic aromatic amines by liver cytosol of species displaying different organ susceptibilities. Biochem. Pharmacol. 22: 1581-1588.
    • (1973) Biochem. Pharmacol. , vol.22 , pp. 1581-1588
    • Lower G.M., Jr.1    Bryan, G.T.2
  • 76
    • 0018330592 scopus 로고
    • N-Acetyltransferase phenotype and risk in urinary bladder cancer: Approaches in molecular epidemiology. Preliminary results in Sweden and Denmark. Environ
    • Lower, G. M., Jr., Nilsson, T., Nelson, C. E., Wolf, H., Gamsky, T. E. and Bryan, G. T. (1979) N-Acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark. Environ. Health Perspect. 29:71-79.
    • (1979) Health Perspect. , vol.29 , pp. 71-79
    • Lower G.M., Jr.1    Nilsson, T.2    Nelson, C.E.3    Wolf, H.4    Gamsky, T.E.5    Bryan, G.T.6
  • 78
    • 0019171487 scopus 로고
    • Studies on the macromolecular binding of benzidine
    • Martin, C. N. and Ekers, S. F. (1980) Studies on the macromolecular binding of benzidine. Carcinogenesis 1: 101-109.
    • (1980) Carcinogenesis , vol.1 , pp. 101-109
    • Martin, C.N.1    Ekers, S.F.2
  • 79
    • 0018147221 scopus 로고
    • Testing of known carcinogens and noncarcinogens for their ability to induce unscheduled DNA synthesis in HeLa cells
    • Martin, C. N., McDermid, A. C. and Garner, R. C. (1978) Testing of known carcinogens and noncarcinogens for their ability to induce unscheduled DNA synthesis in HeLa cells. Cancer Res. 38: 2621-2627.
    • (1978) Cancer Res. , vol.38 , pp. 2621-2627
    • Martin, C.N.1    McDermid, A.C.2    Garner, R.C.3
  • 80
    • 0019953879 scopus 로고
    • Covalent binding of benzidine and N-acetylbenzidine to DNA at the C-8 atom of deoxyguanosine in vivo and in vitro
    • Martin, C. N., Beland, F. A., Roth, R. W. and Kadlubar, F. F. (1982) Covalent binding of benzidine and N-acetylbenzidine to DNA at the C-8 atom of deoxyguanosine in vivo and in vitro. Cancer Res. 42: 2678-2696.
    • (1982) Cancer Res. , vol.42 , pp. 2678-2696
    • Martin, C.N.1    Beland, F.A.2    Roth, R.W.3    Kadlubar, F.F.4
  • 81
    • 0000489708 scopus 로고
    • Evaluation of the mutagenic activity of coded compounds in the Salmonella test
    • Martire, G., Vricella, G., Perfumo, A. M. and DeLorenzo, F. (1981) Evaluation of the mutagenic activity of coded compounds in the Salmonella test. Prog. Mutat. Res. 1: 271-279.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 271-279
    • Martire, G.1    Vricella, G.2    Perfumo, A.M.3    DeLorenzo, F.4
  • 83
    • 0020644301 scopus 로고
    • The use of cells from rat, mouse, hamster, and rabbit in the hepatocyte primary culture/DNA-repair test
    • McQueen, C. A. and Williams, G. M. (1983) The use of cells from rat, mouse, hamster, and rabbit in the hepatocyte primary culture/DNA-repair test. Ann. NY Acad. Sci. 1503: 119-130.
    • (1983) Ann. NY Acad. Sci. , vol.1503 , pp. 119-130
    • McQueen, C.A.1    Williams, G.M.2
  • 84
    • 0023197508 scopus 로고
    • Biotransformation of aromatic amines to DNA-damaging products by urinary bladder organ cultures
    • McQueen, C. A., Way, B. M. and Williams, G. M. (1987) Biotransformation of aromatic amines to DNA-damaging products by urinary bladder organ cultures. Carcinogenesis 8: 401-404.
    • (1987) Carcinogenesis , vol.8 , pp. 401-404
    • McQueen, C.A.1    Way, B.M.2    Williams, G.M.3
  • 85
    • 0011733118 scopus 로고
    • A study of exposure to benzidme and substituted benzidine in a chemical plant
    • Meigs, J. W., Brown, R. M. and Sciarini, L. J. (1951) A study of exposure to benzidme and substituted benzidine in a chemical plant. Arch. Ind. Hyg. Occup. Med. 4: 533-540.
    • (1951) Arch. Ind. Hyg. Occup. Med. , vol.4 , pp. 533-540
    • Meigs, J.W.1    Brown, R.M.2    Sciarini, L.J.3
  • 86
    • 0022634721 scopus 로고
    • Bladder tumor incidence among workers exposed to benzidine: A thirty-year follow up
    • Meigs, J. W., Marrett, L. D., Ulrich, F. U. and Flannery, J. T. (1986) Bladder tumor incidence among workers exposed to benzidine: a thirty-year follow up. J. Natl. Cancer Inst. 76: 1-8.
    • (1986) J. Natl. Cancer Inst. , vol.76 , pp. 1-8
    • Meigs, J.W.1    Marrett, L.D.2    Ulrich, F.U.3    Flannery, J.T.4
  • 88
    • 0020397479 scopus 로고
    • Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay
    • Mirsalis, J. C., Tyson, C. K. and Butterworth, B. E. (1982) Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay. Environ. Mutagen. 4: 553-562.
    • (1982) Environ. Mutagen. , vol.4 , pp. 553-562
    • Mirsalis, J.C.1    Tyson, C.K.2    Butterworth, B.E.3
  • 89
    • 0018762584 scopus 로고
    • Metabolism of benzidine to N-hydroxy-N,N'-diacetylbenzidine and subsequent nucleic acid binding and mutagenicity
    • Morton, K. C., King, C. M. and Baetcke, K. P. (1979) Metabolism of benzidine to N-hydroxy-N,N'-diacetylbenzidine and subsequent nucleic acid binding and mutagenicity. Cancer Res. 39: 3107-3113.
    • (1979) Cancer Res. , vol.39 , pp. 3107-3113
    • Morton, K.C.1    King, C.M.2    Baetcke, K.P.3
  • 90
    • 0018906385 scopus 로고
    • Metabolic activation of N-hydroxy-N,N'-diacetylbenzidine by hepatic sulfotransferase
    • Morton, K. C., Beland, F. A., Evans, F. E., Fullerton, N. F. and Kadlubar, F. F. (1980) Metabolic activation of N-hydroxy-N,N'-diacetylbenzidine by hepatic sulfotransferase. Cancer Res. 40: 751-757.
    • (1980) Cancer Res. , vol.40 , pp. 751-757
    • Morton, K.C.1    Beland, F.A.2    Evans, F.E.3    Fullerton, N.F.4    Kadlubar, F.F.5
  • 91
    • 0020536827 scopus 로고
    • Prostaglandin H synthase-mediated reaction of carcinogenic arylamines with tRNA and homopolyribonucleotides
    • Morton, K. C., King, C. M., Vaught, J. B., Wang, C. Y., Lee, M. S. and Marnett, L. J. (1983) Prostaglandin H synthase-mediated reaction of carcinogenic arylamines with tRNA and homopolyribonucleotides. Biochem. Biophy. Res. Commun. 11: 96-103.
    • (1983) Biochem. Biophy. Res. Commun. , vol.11 , pp. 96-103
    • Morton, K.C.1    King, C.M.2    Vaught, J.B.3    Wang, C.Y.4    Lee, M.S.5    Marnett, L.J.6
  • 92
    • 0000288759 scopus 로고
    • Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay
    • Nagao, M. and Takahashi, Y. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. Prog. Mutat. Res. 1: 302-313.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 302-313
    • Nagao, M.1    Takahashi, Y.2
  • 93
    • 0000288757 scopus 로고
    • Mutagenic activity of 20 coded compounds in chromosome aberrations/sister chromatid exchanges assay using Chinese hamster ovary (CHO) cells
    • Natarajan, A. T. and van Kesteren-van Leeuwen, A. C. (1981) Mutagenic activity of 20 coded compounds in chromosome aberrations/sister chromatid exchanges assay using Chinese hamster ovary (CHO) cells. Prog. Mutat. Res. 1: 551-559.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 551-559
    • Natarajan, A.T.1    Van Kesteren-Van Leeuwen, A.C.2
  • 94
    • 0020670550 scopus 로고
    • Chemically-induced sister-chromatid exchange in vivo in bone marrow of Chinese hamsters
    • Neal, S. B. and Probst, G. S. (1983) Chemically-induced sister-chromatid exchange in vivo in bone marrow of Chinese hamsters. Mutat. Res. 113: 33-43.
    • (1983) Mutat. Res. , vol.113 , pp. 33-43
    • Neal, S.B.1    Probst, G.S.2
  • 95
    • 0019991159 scopus 로고
    • The influence of sex, dose, time and cross on neoplasia in mice given benzidine dihydrochloride
    • Nelson, C. J., Baetcke, K. P., Frith, C. H., Kodell, R. L. and Schieferstein, G. (1982) The influence of sex, dose, time and cross on neoplasia in mice given benzidine dihydrochloride. Toxicol. Appl. Pharmacol. 64: 171-186.
    • (1982) Toxicol. Appl. Pharmacol. , vol.64 , pp. 171-186
    • Nelson, C.J.1    Baetcke, K.P.2    Frith, C.H.3    Kodell, R.L.4    Schieferstein, G.5
  • 96
    • 0021329775 scopus 로고
    • +/- mouse lymphoma forward mutation assay using 42 chemicals
    • +/- mouse lymphoma forward mutation assay using 42 chemicals. Mutat. Res. 125: 291-306.
    • (1984) Mutat. Res. , vol.125 , pp. 291-306
    • Oberly, T.J.1    Bewsey, B.J.2    Probst, G.S.3
  • 97
    • 0021024646 scopus 로고
    • Bovine bladder urothelial cell activation of carcinogens to metabolites mutagenic to Chinese hamster V79 cells and Salmonella typhimurium
    • Oglesby, L. A., Hix, C., Snow, L., Mac Nair, P., Seig, M. and Langerbach, R. (1983) Bovine bladder urothelial cell activation of carcinogens to metabolites mutagenic to Chinese hamster V79 cells and Salmonella typhimurium. Cancer Res. 43: 5194-5199.
    • (1983) Cancer Res. , vol.43 , pp. 5194-5199
    • Oglesby, L.A.1    Hix, C.2    Snow, L.3    Mac Nair, P.4    Seig, M.5    Langerbach, R.6
  • 99
    • 0019770331 scopus 로고
    • DNA-damaging activity in vivo and bacterial mutagenicity of sixteen aromatic amines and azo-derivatives, as related quantitatively to their carcinogenicity
    • Parodi, S., Taningher, M., Russo, P., Pala, M., Tamaro, M. and Monti-Bragadin, C. (1981) DNA-damaging activity in vivo and bacterial mutagenicity of sixteen aromatic amines and azo-derivatives, as related quantitatively to their carcinogenicity. Carcinogenesis 2: 1317-1326.
    • (1981) Carcinogenesis , vol.2 , pp. 1317-1326
    • Parodi, S.1    Taningher, M.2    Russo, P.3    Pala, M.4    Tamaro, M.5    Monti-Bragadin, C.6
  • 100
    • 0020047177 scopus 로고
    • Quantitative correlations amongst alkaline DNA fragmentation, DNA covalent binding, mutagenicity in the Ames test and carcinogenicity, for 21 compounds
    • Parodi, S., Taningher, M., Boero, P. and Santi, L. (1982) Quantitative correlations amongst alkaline DNA fragmentation, DNA covalent binding, mutagenicity in the Ames test and carcinogenicity, for 21 compounds. Mutat. Res. 93: 1-24.
    • (1982) Mutat. Res. , vol.93 , pp. 1-24
    • Parodi, S.1    Taningher, M.2    Boero, P.3    Santi, L.4
  • 101
    • 0020615039 scopus 로고
    • Lack of correlation between the capability of inducing sister-chromatid exchanges in vivo and carcinogenic potency, for 16 aromatic amines and azo derivatives
    • Parodi, S., Zunino, A., Ottaggio, L., De Ferrari, M. and Santi, L. (1983) Lack of correlation between the capability of inducing sister-chromatid exchanges in vivo and carcinogenic potency, for 16 aromatic amines and azo derivatives. Mutat. Res. 108: 225-238.
    • (1983) Mutat. Res. , vol.108 , pp. 225-238
    • Parodi, S.1    Zunino, A.2    Ottaggio, L.3    De Ferrari, M.4    Santi, L.5
  • 102
    • 0001069366 scopus 로고
    • Evaluation of the sister chromatid exchange method in mammalian cells as a screening system for carcinogens
    • Perry, P. E. and Thomson, E. J. (1981) Evaluation of the sister chromatid exchange method in mammalian cells as a screening system for carcinogens. Prog. Mutat. Res. 1: 560-569.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 560-569
    • Perry, P.E.1    Thomson, E.J.2
  • 103
    • 0018193831 scopus 로고
    • Detection of DNA damage induced in vivo following exposure of rats to carcinogens
    • Petzold, G. L. and Swenberg, J. A. (1978) Detection of DNA damage induced in vivo following exposure of rats to carcinogens. Cancer Res. 38: 1589-1594.
    • (1978) Cancer Res. , vol.38 , pp. 1589-1594
    • Petzold, G.L.1    Swenberg, J.A.2
  • 104
    • 0025073954 scopus 로고
    • Determination of benzidine-DNA adduct formation in CHO, HeLa, L5178Y, TK6 and V79 cells
    • Phillips, D. H., Cross, M. F., Kennelly, J. C., Wilcox, P. and O'Donovan, M. R. (1990) Determination of benzidine-DNA adduct formation in CHO, HeLa, L5178Y, TK6 and V79 cells. Mutagenesis 5: 67-69.
    • (1990) Mutagenesis , vol.5 , pp. 67-69
    • Phillips, D.H.1    Cross, M.F.2    Kennelly, J.C.3    Wilcox, P.4    O'Donovan, M.R.5
  • 105
    • 0000782849 scopus 로고
    • The N-and ring-hydroxylation of 2-acetylaminofluorene and the failure to detect N-acetylation of 2-aminofluorene in the dog
    • Poirier, L. A., Miller, J. A. and Miller, E. C. (1963) The N-and ring-hydroxylation of 2-acetylaminofluorene and the failure to detect N-acetylation of 2-aminofluorene in the dog. Cancer Res. 23: 790-800.
    • (1963) Cancer Res. , vol.23 , pp. 790-800
    • Poirier, L.A.1    Miller, J.A.2    Miller, E.C.3
  • 106
    • 0020062943 scopus 로고
    • Analysis of a method for testing azo dyes for mutagenic activity in Salmonella typhimurium in the presence of flavin mononucleotide and hamster liver S9
    • Prival, M. J. and Mitchell, V. D. (1982) Analysis of a method for testing azo dyes for mutagenic activity in Salmonella typhimurium in the presence of flavin mononucleotide and hamster liver S9. Mutat. Res. 97: 103-116.
    • (1982) Mutat. Res. , vol.97 , pp. 103-116
    • Prival, M.J.1    Mitchell, V.D.2
  • 107
    • 0021139085 scopus 로고
    • Mutagenicity of benzidine and benzidine-congener dyes and selected monoazo dyes in a modified Salmonella assay
    • Prival, M. J., Bell, S. J., Mitchell, V. D., Peiperl, M. D. and Vaughan, V. L. (1984) Mutagenicity of benzidine and benzidine-congener dyes and selected monoazo dyes in a modified Salmonella assay. Mutat. Res. 136: 33-47.
    • (1984) Mutat. Res. , vol.136 , pp. 33-47
    • Prival, M.J.1    Bell, S.J.2    Mitchell, V.D.3    Peiperl, M.D.4    Vaughan, V.L.5
  • 108
    • 0019796035 scopus 로고
    • Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: A comparison with bacterial mutagenicity using 218 compounds
    • Probst, G. S., McMahon, R. E., Hill, L. E., Thompson, C. Z., Epp, J. K. and Neal, S. B. (1981) Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: a comparison with bacterial mutagenicity using 218 compounds. Environ. Mutagen. 3: 11-32.
    • (1981) Environ. Mutagen. , vol.3 , pp. 11-32
    • Probst, G.S.1    McMahon, R.E.2    Hill, L.E.3    Thompson, C.Z.4    Epp, J.K.5    Neal, S.B.6
  • 109
    • 18544398135 scopus 로고
    • Induction of hepatic tumors in mice by benzidine
    • Prokofjeva, O. G. (1971) Induction of hepatic tumors in mice by benzidine. Vopr. Onkol. 17: 61-64.
    • (1971) Vopr. Onkol. , vol.17 , pp. 61-64
    • Prokofjeva, O.G.1
  • 112
    • 0000288761 scopus 로고
    • Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay
    • Richold, M. and Jones, E. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. Prog. Mutat. Res. 1: 314-322.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 314-322
    • Richold, M.1    Jones, E.2
  • 113
    • 0016723412 scopus 로고
    • Metabolic reduction of benzidine azo dyes to benzidine in the Rhesus monkey
    • Rinde, E. and Troll, W. (1975) Metabolic reduction of benzidine azo dyes to benzidine in the Rhesus monkey. J. Natl. Cancer Inst. 55: 181-182.
    • (1975) J. Natl. Cancer Inst. , vol.55 , pp. 181-182
    • Rinde, E.1    Troll, W.2
  • 114
  • 115
    • 0000762662 scopus 로고
    • Unscheduled DNA synthesis response of human fibroblasts, WI-38 cells, to 20 coded chemicals
    • Robinson, D. E. and Mitchell, A. D. (1981) Unscheduled DNA synthesis response of human fibroblasts, WI-38 cells, to 20 coded chemicals. Prog. Mutat. Res. 1: 517-527.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 517-527
    • Robinson, D.E.1    Mitchell, A.D.2
  • 116
    • 0000592458 scopus 로고
    • Mutagenicity of carcinogens and noncarcinogens in the Salmonella/microsome test
    • Rowland, I. and Severn, B. (1981) Mutagenicity of carcinogens and noncarcinogens in the Salmonella/microsome test. Prog. Mutat. Res. 1: 323-332.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 323-332
    • Rowland, I.1    Severn, B.2
  • 117
    • 0011758862 scopus 로고
    • Induction of bladder cancer in hamsters fed aromatic amines
    • Lampe, K. F. (ed.) Aesculapius Publishing Co., Birmingham
    • Saffiotti, U., Cefis, F. and Montesano, R. (1967) Induction of bladder cancer in hamsters fed aromatic amines. In: Bladder Cancer: A Symposium, pp. 129-135, Lampe, K. F. (ed.) Aesculapius Publishing Co., Birmingham.
    • (1967) Bladder Cancer: A Symposium , pp. 129-135
    • Saffiotti, U.1    Cefis, F.2    Montesano, R.3
  • 118
    • 0000094058 scopus 로고
    • Mutagenic activity of 41 compounds in the in vivo micronucleus assay
    • Salamone, M. F., Heddle, J. A. and Katz, M. (1981) Mutagenic activity of 41 compounds in the in vivo micronucleus assay. Prog. Mutat. Res. 1: 686-697.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 686-697
    • Salamone, M.F.1    Heddle, J.A.2    Katz, M.3
  • 119
    • 0011794282 scopus 로고
    • The biotransformation of benzidine (4,4′-diaminobiphenyl), an industrial carcinogen in the dog
    • Sciarini, L. J. and Meigs, J. W. (1958) The biotransformation of benzidine (4,4′-diaminobiphenyl), an industrial carcinogen in the dog. Arch. Ind. Health 18: 521-542.
    • (1958) Arch. Ind. Health , vol.18 , pp. 521-542
    • Sciarini, L.J.1    Meigs, J.W.2
  • 120
    • 0001541928 scopus 로고
    • The biotransformation of benzidine. II. Studies in mouse and man
    • Sciarini, L. J. and Meigs, J. W. (1961) The biotransformation of benzidine. II. studies in mouse and man. Arch. Environ. Health 2: 423-428.
    • (1961) Arch. Environ. Health , vol.2 , pp. 423-428
    • Sciarini, L.J.1    Meigs, J.W.2
  • 121
    • 0011761862 scopus 로고
    • The incidence of bladder tumours in a dye-stuffs factory
    • Scott, T. S. (1952) The incidence of bladder tumours in a dye-stuffs factory. Br. J. Ind. Med. 9: 127-132.
    • (1952) Br. J. Ind. Med. , vol.9 , pp. 127-132
    • Scott, T.S.1
  • 122
    • 0024365294 scopus 로고
    • Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/ PSK1002
    • Shimada, T., Iwasaki, M., Martin, M. V. and Guengerich, F. P. (1989) Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/ PSK1002. Cancer Res. 49: 3218-3228.
    • (1989) Cancer Res. , vol.49 , pp. 3218-3228
    • Shimada, T.1    Iwasaki, M.2    Martin, M.V.3    Guengerich, F.P.4
  • 123
    • 0000288760 scopus 로고
    • Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay
    • Simmon, V. F. and Shepherd, G. F. (1981) Mutagenic activity of 42 coded compounds in the Salmonella/microsome assay. Prog. Mutat. Res. 1: 333-342.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 333-342
    • Simmon, V.F.1    Shepherd, G.F.2
  • 124
    • 0020554051 scopus 로고
    • Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential
    • Sina, J. F., Bean, C. L., Dysart, G. R., Taylor, V. I. and Bradley, M. O. (1983) Evaluation of the alkaline elution/rat hepatocyte assay as a predictor of carcinogenic/mutagenic potential. Mutat. Res. 113: 357-391.
    • (1983) Mutat. Res. , vol.113 , pp. 357-391
    • Sina, J.F.1    Bean, C.L.2    Dysart, G.R.3    Taylor, V.I.4    Bradley, M.O.5
  • 125
    • 0025812436 scopus 로고
    • Bioactivation of xenobiotics by prostaglandin H synthase
    • Smith, B. J., Curtis, J. F. and Eling, T. E. (1991) Bioactivation of xenobiotics by prostaglandin H synthase. Chem. Biol. Interact. 79: 245-264.
    • (1991) Chem. Biol. Interact. , vol.79 , pp. 245-264
    • Smith, B.J.1    Curtis, J.F.2    Eling, T.E.3
  • 126
    • 0000178426 scopus 로고
    • The carcinogenic action of benzidine
    • Spitz, S., Maguigan, W. H. and Dobriner, K. (1950) The carcinogenic action of benzidine. Cancer 3: 789-804.
    • (1950) Cancer , vol.3 , pp. 789-804
    • Spitz, S.1    Maguigan, W.H.2    Dobriner, K.3
  • 127
    • 0016239661 scopus 로고
    • Starke cancerogene wirkung von benzidin lei weillichen Sprague-Dawley ratten
    • Steinhoff, D. (1974) Starke cancerogene wirkung von benzidin lei weillichen Sprague-Dawley ratten. Naturwissenschaften 61: 276-277.
    • (1974) Naturwissenschaften , vol.61 , pp. 276-277
    • Steinhoff, D.1
  • 128
    • 0018839633 scopus 로고
    • Mutagenicity of extracts of urine from rats treated with aromatic amines
    • Tanaka, K. I., Marui, S. and Mii, T. (1980) Mutagenicity of extracts of urine from rats treated with aromatic amines. Mutat. Res. 79: 173-176.
    • (1980) Mutat. Res. , vol.79 , pp. 173-176
    • Tanaka, K.I.1    Marui, S.2    Mii, T.3
  • 129
    • 0020375989 scopus 로고
    • Some aspects of metabolism and mutagenicity of o-tolidine and an o-tolidine-based azo dye
    • Tanaka, K. I., Mii, T., Marui, S., Matsubara, I. and Igaki, H. (1982) Some aspects of metabolism and mutagenicity of o-tolidine and an o-tolidine-based azo dye. Ind. Health 20: 227-235.
    • (1982) Ind. Health , vol.20 , pp. 227-235
    • Tanaka, K.I.1    Mii, T.2    Marui, S.3    Matsubara, I.4    Igaki, H.5
  • 130
    • 0017668960 scopus 로고
    • Carcinogen activation by human liver enzymes in the Ames mutagenicity test
    • Tang, T. and Friedman, M. A. (1977) Carcinogen activation by human liver enzymes in the Ames mutagenicity test. Mutat. Res. 46: 387-394.
    • (1977) Mutat. Res. , vol.46 , pp. 387-394
    • Tang, T.1    Friedman, M.A.2
  • 132
    • 0017280828 scopus 로고
    • An evaluation of the mutagenicity of the cutting oil preservative grotan BK
    • Urwin, C., Richardson, J. C. and Palmer, A. K. (1976) An evaluation of the mutagenicity of the cutting oil preservative grotan BK. Mutat. Res. 40: 43-46.
    • (1976) Mutat. Res. , vol.40 , pp. 43-46
    • Urwin, C.1    Richardson, J.C.2    Palmer, A.K.3
  • 134
    • 0018653180 scopus 로고
    • Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test
    • Venturini, S. and Tamaro, J. (1979) Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test. Mutat. Res. 68: 307-312.
    • (1979) Mutat. Res. , vol.68 , pp. 307-312
    • Venturini, S.1    Tamaro, J.2
  • 135
    • 0016768740 scopus 로고
    • Factors modulating benzidine carcinogenicity bioassay
    • Vesselinovitch, S. D., Rao, K. V. N. and Mihailovich, N. (1975) Factors modulating benzidine carcinogenicity bioassay. Cancer Res. 35: 2814-2819.
    • (1975) Cancer Res. , vol.35 , pp. 2814-2819
    • Vesselinovitch, S.D.1    Rao, K.V.N.2    Mihailovich, N.3
  • 136
    • 0001190432 scopus 로고
    • Environmental tumors of the bladder in some Italian dye-stuff factories
    • Vigliani, E. C. and Barsotti, M. (1961) Environmental tumors of the bladder in some Italian dye-stuff factories. Med. Lav. 52: 241-250.
    • (1961) Med. Lav. , vol.52 , pp. 241-250
    • Vigliani, E.C.1    Barsotti, M.2
  • 138
    • 0025316483 scopus 로고
    • Production of urothelial tumors in the heterotopic bladder of rat by benzidine derivatives
    • Wang, C. Y., Zukowski, K., Yamada, H., Imaida, K. and Lee, M. S. (1990) Production of urothelial tumors in the heterotopic bladder of rat by benzidine derivatives. Cancer Res. 50: 2868-2871.
    • (1990) Cancer Res. , vol.50 , pp. 2868-2871
    • Wang, C.Y.1    Zukowski, K.2    Yamada, H.3    Imaida, K.4    Lee, M.S.5
  • 139
    • 0021813284 scopus 로고
    • N-acetylation pharmacogenetics
    • Weber, W. W. and Hein, D. W. (1985) N-acetylation pharmacogenetics. Phannacol. Rev. 37: 25-79.
    • (1985) Phannacol. Rev. , vol.37 , pp. 25-79
    • Weber, W.W.1    Hein, D.W.2
  • 140
    • 0017876294 scopus 로고
    • Further improvements in the hepatocyte primary culture DNA repair test for carcinogens: Detection of carcinogenic biphenyl derivatives
    • Williams, G. M. (1978) Further improvements in the hepatocyte primary culture DNA repair test for carcinogens: detection of carcinogenic biphenyl derivatives. Cancer Lett. 4: 69-75.
    • (1978) Cancer Lett. , vol.4 , pp. 69-75
    • Williams, G.M.1
  • 141
    • 0020319079 scopus 로고
    • Mammalian culture systems for the study of genetic effects of N-substituted aryl compounds
    • Williams, G. M. (1981) Mammalian culture systems for the study of genetic effects of N-substituted aryl compounds. Natl. Cancer Inst. Monogr. 58: 237-242.
    • (1981) Natl. Cancer Inst. Monogr. , vol.58 , pp. 237-242
    • Williams, G.M.1
  • 143
    • 0021702029 scopus 로고
    • Characterization of benzidine diimine: A product of peroxidase metabolism of benzidine
    • Wise, R. W., Zenser, T. V. and Davis, B. B. (1984) Characterization of benzidine diimine: a product of peroxidase metabolism of benzidine. Carcinogenesis 5: 1499-1503.
    • (1984) Carcinogenesis , vol.5 , pp. 1499-1503
    • Wise, R.W.1    Zenser, T.V.2    Davis, B.B.3
  • 144
    • 0022645143 scopus 로고
    • Peroxidative metabolism of benzidine by intact tissue: A prostaglandin H synthase-mediated process
    • Wise, R. W., Zenser, T. V., Rice, J. R. and Davis, B. B. (1986) Peroxidative metabolism of benzidine by intact tissue: a prostaglandin H synthase-mediated process. Carcinogenesis 7: 111-115.
    • (1986) Carcinogenesis , vol.7 , pp. 111-115
    • Wise, R.W.1    Zenser, T.V.2    Rice, J.R.3    Davis, B.B.4
  • 145
    • 0000539928 scopus 로고
    • Bladder cancer in workers of the dyeing industry
    • Yosbida, O., Harada, T., Kato, T. and Miyakawa, M. (1971) Bladder cancer in workers of the dyeing industry. Igaku No Ayumi 79: 421-422.
    • (1971) Igaku No Ayumi , vol.79 , pp. 421-422
    • Yosbida, O.1    Harada, T.2    Kato, T.3    Miyakawa, M.4
  • 146
    • 0015783392 scopus 로고
    • Benzidine exposure as a cause of bladder tumors
    • Zavon, M. R., Hoegg, U. and Bingham, E. (1973) Benzidine exposure as a cause of bladder tumors. Arch. Environ. Health 27: 1-7.
    • (1973) Arch. Environ. Health , vol.27 , pp. 1-7
    • Zavon, M.R.1    Hoegg, U.2    Bingham, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.