Insulin treatment normalizes reduced free insulin-like growth factor-I concentrations in diabetic children

Clinical Endocrinology

Volumn 45, Issue 3, 1996, Pages 321-326

  Bereket, Abdullah ^a   Lang, Charles H ^b   Blethen, Sandra L ^a   Ng, Lydia Co ^a   Wilson, Thomas A ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; SOMATOMEDIN BINDING PROTEIN; SOMATOMEDIN C;

ADOLESCENT; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0029747031     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1996.7760786.x     Document Type: Article

References (23)

1. Bereket, A., Lang, C.H., Blethen, S.L., Gelato, M.C., Fan, J., Frost, R.A. & Wilson, T.A. (1995a) Effect of insulin on the IGF system in children with new onset insulin dependent diabetes mellitus. Journal of Clinical Endocrinology and Metabolism, 80, 1312-1317.
2. Bereket, A., Lang, C.H., Blethen, S.L., Fan, J., Frost, R.A. & Wilson, T.A. (1995b) Insulin-like growth factor binding protein-3 proteolysis in children with insulin dependent diabetes mellitus: A possible role for insulin in the regulation of IGFBP-3 protease activity. Journal of Clinical Endocrinology and Metabolism, 80, 2282-2288.
3. Binoux, M., Lalou, C., Lasarre, C., Blat, C. & Hossenlopp, P. (1994) Limited proeteolysis of insulin-like growth factor binding protein-3 (IGFBP-3): A physiological mechanism in the regulation of IGF bioavailability. In Current Directions in Insulin-like Growth Factor Research (eds D. Le Roith & M.K. Raizada). pp. 293-300. Plenum Press, New York.
4. Bornfeldt, K.E., Skottner, A. & Arnqvist, H.J. (1992) In-vivo regulation of messenger RNA encoding insulin-like growth factor-I (IGF-I) and its receptor by diabetes, insulin and IGF-I in rat muscle. Journal of Endocrinology, 135, 203-211.
5. Böni-Schnetzler, M., Schmid, C., Meier, J.P. & Froesch, E.R. (1991) Insulin regulates insulin-like growth factor I mRNA in rat hepatocytes. American Journal of Physiology, 260, E846-E851.
6. Brismar, K., Fernqvist-Forbes, E., Wahren, J. & Hall, K. (1994) Effect of insulin on the hepatic production of insulin-like growth factor binding protein-I (IGFBP-1), IGFBP-3, and IGF-I in insulin-dependent diabetes. Journal of Clinical Endocrinology and Metabolism, 79, 872-878.
7. Cheetham, T.D., Jones, J., Taylor, A.M., Holly, J., Matthews, D.R. & Dunger, D.B. (1993) The effects of recombinant insulin-like growth factor I administration on growth hormone levels and insulin requirements in adolescents with Type I (insulin-dependent) diabetes mellitus. Diabetologia, 36, 678-681.
8. Cohick, W.S. & Clemmons, D.R. (1993) The insulin-like growth factors. Annual Review of Physiology, 55, 131-153.
9. Cotterill, A.M., Daly, F., Holly, J.M., Hughes, S.C., Camacho-Hubner, C., Abdulla, A.F., Gale, E.A. & Savage, M.O. (1995) The 'dawn phenomenon' in adolescents wilh insulin dependent diabetes mellitus: possible contribution of insulin-like growth factor binding protein-1. Clinical Endocrinology, 43, 567-574.
10. Counts, D.R., Gwirtsman, H., Carlsson, L.M.S., Lesem, M. & Cutler, G.B. (1992) The effect of anorexia nervosa and refeeding on growth hormone binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. Journal of Clinical Endocrinology and Metabolism, 75, 762-767.
11. Daughaday, W.H., Ward, A.P., Goldberg, A.C., Trivedi, B. & Kapadia, M. (1982) Characterization of somatomedin binding in human serum by ultracentrifugation and gel filtration. Journal of Clinical Endocrinology and Metabolism, 55, 916-921.
12. Frost, R.A., Bereket, A., Wilson, T.A., Wojnar, M.M., Lang, C.H. & Gelato, M.C. (1994) Phosphorylation of insulin-like growth factor binding protein-1 in patients with insulin dependent diabetes mellitus and severe trauma. Journal of Clinical Endocrinology and Metabolism, 78, 1533-1535.
13. Graubert, M.D. Goldstein, S. & Phillips, L.S. (1991) Nutrition and somatomedin XXVII. Total and free IGF-I and IGF binding proteins in rats with streptozocin-induced diabetes. Diabetes, 40, 959-965.
14. Guler, H.-P., Zapf, J. & Froesch, E.R. (1987) Short term metabolic effects of recombinant human insulin-like growth factor-I in healthy adults. New England Journal of Medicine, 317, 137-140.
15. Guler, H.-P., Zapf, J., Schmid, C. & Froesch, E.R. (1989) Insulin-like growth factors I and II in healthy man. Estimations of half-lives and production rates. Acta Endocrinological (Copenh), 121, 753-758.
16. Jones, J.I., D'Ercole, A.J., Camacho-Hubner, C. & Clemmons, D.R. (1991) Phosphorylation of insulin like growth factor (IGF) binding protein-I in cell cultures and in vivo: effects of affinity for IGF-I. Proceedings of the National Academy of Sciences USA, 88, 7481-7485.
17. Lee, P.D.K., Powell, D., Baker, B., Liu, F., Mathew, G., Levitsky, I., Gutierrez, O.D. & Hintz, R.L. (1994) Characterization of a direct, non-extraction immunoradiometric assay for free IGF-I. Proceedings of the 76th Endocrine Society Meeting, Anaheim, CA, (abstr. 939).
18. Lewitt, M.S., Denyer, G.S., Cooney, G.J. & Baxter, R.C. (1991) Insulin-like growth factor-binding protein-1 modulates blood glucose levels. Endocrinology, 129, 2254-2256.
19. Ooi, G.T., Tseng, L.Y-H. & Rechler, M.M. (1992) Post-transcriptional regulation of insulin-like growth factor binding protein-2 mRNA in diabetic rat liver. Biochemical and Biophysical Research Communications, 189, 1031-1037.
20. Phillips, L.S., Goldstein, S. & Pao, C.-I. (1991) Nutrition and Somatomedin. Molecular regulation of IGF-I by insulin in cultured rat hepatocytes. Diabetes, 40, 1525-1530.
21. Taylor, A.M., Dunger, D.B., Preece, M.A., Holly, J.M.P., Smith, C.P., Wass, J.A.H., Patel, S. & Tate, V.E. (1990) The growth hormone independent insulin-like growth factor-I binding protein BP-28 is associated with serum insulin-like growth factor-I inhibitory bioactivity in adolescent insulin-dependent diabetics. Clinical Endocrinology, 32, 229-239.
22. Winter, R.J., Phillips, L.S., Klein, M.N., Traisman, H.S. & Green, O.C. (1979) Somatomedin activity and diabetic control in children with insulin-dependent diabetes. Diabetes, 28, 952-954
23. Zapf, J., Hauri, C., Waldvogel, M. & Froesch, E.R. (1986) Acute metabolic effects and half-lives of intravenously administered insulin-like growth factors I and II in normal and hypophysectomized rats. Journal of Clinical Investigation, 77, 1768-1775.