pH-Sensitive liposomes and antisense oligonucleotide delivery

Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents

Volumn 3, Issue 2, 1996, Pages 67-73

  Milhaud, Pierre G ^a,b   Bongartz, Jean Pierre ^a   Lebleu, Bernard ^a   Philippot, Jean R ^a  

^a UNIV MONTPELLIER   (France)

^b INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

Author keywords

Antisense; Drug delivery; Liposomes; Oligonucleotides; pH sensitive

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CALCIUM; CHOLESTEROL; CHOLESTEROL HYDROGEN SUCCINATE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPOSOME; OLEIC ACID; POLYINOSINIC POLYCYTIDYLIC ACID;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DRUG ADMINISTRATION; DRUG DELIVERY SYSTEM; ENCAPSULATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PH; PHARMACEUTICS; PRIORITY JOURNAL; SERUM; TOXICITY; VESICULAR STOMATITIS VIRUS;

EID: 0029746709     PISSN: 10717544     EISSN: None     Source Type: Journal    
DOI: 10.3109/10717549609031175     Document Type: Article

References (32)

1. Wang, C. Y., and Huang, L. (1987) pH-Sensitive immunoliposomes mediate target cell-specific delivery and controlled expression of a foreign gene in mouse. Proc. Natl. Acad. Sci. USA 84, 7851-7855.
2. Wang, C. Y., and Huang, L. (1989) Highly efficient DNA delivery mediated by pH-sensitive immunoliposomes. Biochemistry 28, 9508-9514.
3. Legendre, J.-Y., and Szoka, F. C. (1992) Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes. Pharm. Res. 9, 1235-1242.
4. Milhaud, P. G., Compagnon, B., Bienvenue, A., and Philippot, J. R. (1992) Interferon production of L929 and HeLa cells enhanced by polyriboinosinic acid-polyribocytidylic acid pH-sensitive liposomes. Bioconjugate Chem. 3, 402-407.
5. Litzinger, D. C., and Huang, L. (1992) Phosphatidylethanolamine liposomes: drug delivery, gene transfer and immunodiagnostic applications. Biochim. Biophys. Acta 1113, 201-227.
6. Chu, C. J., Dijkstra, J., Lai, M.-Z., Hong, K., and Szoka, F. C. (1990) Efficiency of cytoplasmic delivery of pH-sensitive liposomes to cells in culture. Pharm. Res. 7, 824-834.
7. Dervan, P. B. (1989) Oligonucleotide recognition of double-helical DNA by triple-helix formation. In "Topics in Molecular and Structural Biology 12, Oligonucleotides: Antisense Inhibitors of Gene Expression" (J. S. Cohen, ed.), pp. 197-210, Macmillan, Houndmills, UK.
8. Helene, C., and Saison-Behmoaras, E. (1994) The antisense strategy: new therapeutic approaches. Med./Sci. 10, 253-273.
9. Blumenfeld, M., and Vasseur, M. (1994) Sense Oligonucleotides: rational ligands for transcription factors. Med J Sci. 10, 253-273.
10. Leonetti, J. P., Machy, P., Degols, G., Lebleu, B., and Leserman, L. (1990) Antibody-targeted liposomes containing oligodeoxynucleotide complementary to viral RNA selectively inhibit viral replication. Proc. Natl. Acad. Sci. USA 87, 2448-2451.
11. Zamecnik, P. C., and Stephenson, M. L. (1978) Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide. Proc. Natl. Acad. Sci. USA 75, 280-284.
12. Leonetti, J. P., Rayner, B., Lemaitre, M., Gagnor, C., Milhaud, P. G., Imbach, J.-L., and Lebleu, B. (1988) Antiviral activity of conjugates between poly(L-lysine) and synthetic oligodeoxyribonucleotides. Gene 72, 323-332.
13. Zelphati, O., Wagner, E., and Leserman, L. (1994) Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes. Antisense Res. 25, 13-25.
14. Schwab, G., Duroux, I., Chavany, C., Helene, C., Saison-Behmoaras, E. (1994) An approach for new anticancer drugs: oncogene-targeted antisense DNA. Ann. Oncol. 5 (Suppl. 4), S55-S58.
15. Philippot, J. R., Mutafschief, M., and Liautard, J. P. (1983) A very mild method allowing the encapsulation of very high amounts of macromolecules into very large (1000 nm) unilamellar liposomes. Biochim. Biophys. Acta 734, 137-143.
16. Wilson, A. P. (1986) Cytotoxocity and viability assay. In "Animal Cell Culture: A Practical Approach" (R. I. Freshney, ed.), pp. 183-216, IRL, Oxford, UK.
17. Milhaud, P. G., Machy, P., Lebleu, B., and Leserman, L. (1989) Antibody targeted liposomes containing poly(rI):poly(rC) exert a specific antiviral and toxic effect on cells primed with interferons a/b or c. Biochim. Biophys. Acta. 987, 15-20.
18. Milhaud, P. G., Silhol, M., Faure, T., and Milhaud, X. (1983) Numerical tables for the direct estimation of virus titres by the maximum likelihood method. Ann. Virol. (Institut Pasteur) 134E, 405-416.
19. Vlaspolder, F., Donkers, E., Harmsen, T., Kraaijeveld, C. A., and Snippe, H. (1989) Rapid bioassay of human interferon by direct enzyme immunoassay of encephalomyocardites virus HEP-2 cell monolayers after a single cycle of infection. J. Virol. Method. 24, 153-158.
20. Snedecor, G. W., and Cochran, W. G. (1967) "Statistical Methods," 6th ed. Iowa University Press, Ames.
21. Shaw, J.-P., Kent, K., Bird, J., Fishback, J., and Froehler, B. (1991) Modified deoxyoligonucleotides stable to exonuclease degradation in serum. Nucleic Acids Res. 19, 747-750.
22. Ellens, H., Bentz, J., and Szoka, F. C. (1984) pH-induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact. Biochemistry 23, 1538-1541.
23. 2+-induced fusion and destabilization of liposomes. Biochemistry 24, 3099-3106.
24. Lai, M.-Z., Vail, W. J., and Szoka, F. C. (1985) Acid- and calcium-induced structural changes in phosphatidylethanolamine membranes stabilized by cholesteryl hemisuccinate. Biochemistry 24, 1654-1661.
25. Bongartz, J.-P., Aubertin, A.-M., Milhaud, P. G., and Lebleu, B. (1994) Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide. Nucleic Acids Res. 22, 4681-4688.
26. Compagnon, B., Milhaud, P. G., Bienvenüe, A., and Philippot, J. R. (1992) Targeting of poly(rI):poly(rC) by fusogenic (F protein) immunoliposomes. Exp. Cell Res. 200, 333-338.
27. Bennet, C. F., Chiang, M.-Y., Chan, H., Shoemaker, J. E. E., and Mirabelli, C. K. (1992) Cationic lipids enhance cellular uptake and activity of phosphorothioate antisense oligonuceotides. Mol. Pharmacol. 41, 1023-1033.
28. Maeda, M., Doi, O., and Akamatsu, Y. (1980) Behavior of vesicular stomatitis virus glycoprotein in mouse LM cells with modified membrane-phospholipids. Biochim. Biophys. Acta 597, 552-563.
29. Schlegel, R., Tralka, T. S., Willingham, M. C., and Pastan, I. (1983) Inhibition of VSV binding and infectivity by phosphatidylserine: Is phosphatidylserine a VSV-binding site? Cell 32, 639-646.
30. Liu, D., and Huang, L. (1989) Small, but not large, unilamellar liposomes composed of dioleylphosphatidylethanol-amine and oleic acid can be stabilized by human plasma. Biochemistry 28, 7700-7707.
31. Ropert, C., Malvy, C, and Couvreur, P. (1993) Inhibition of the Friend retrovirus by antisense oligonucleotides encapsulated in liposomes: mechanism of action. Pharm. Res. 10, 1427-1433.
32. Briscoe, P., Caniggia, I., Graves, A., Benson, B., Huang, L., Tanswell, A. K., and Freeman, B. A. (1995) Delivery of superoxide dismutase to pulmonary epithelium via pH-sensitive liposomes. Am. J. Physiol. 268, (Lung Cell. Mol. Physiol. 12), L374-L380.