Ability of various members of the hsp70 family of chaperones to promote assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90

Journal of Steroid Biochemistry and Molecular Biology

Volumn 58, Issue 3, 1996, Pages 251-258

  Hutchison, K A ^a   Dittmar, K D ^a   Stancato, L F ^a   Pratt, W B ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; GLUCOCORTICOID RECEPTOR; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; TRIAMCINOLONE ACETONIDE;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CONTROLLED STUDY; IMMUNOBLOTTING; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FAMILY; RABBIT; RETICULOCYTE LYSATE; STEROID BINDING;

EID: 0029745722     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-0760(96)00038-6     Document Type: Article

References (35)

1. S.L. Kost D.F. Smith W.P. Sullivan W.J. Welch D.O. Toft Binding of heat shock proteins to the avian progesterone receptor Molec. Cell. Biol. 9 1989 3829 3838
2. D.B. Schowalter W.P. Sullivan N.J. Maihle A.D.W. Dobson O.M. Conneely B.W. O'Malley D.O. Toft Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins J. Biol. Chem. 266 1991 21165 21173
3. S.A. Onate P.A. Estes W.J. Welch S.K. Nordeen D.P. Edwards Evidence that heat shock protein-70 associated with progesterone receptors is not involved in receptor-DNA binding Molec. Endocr. 5 1991 1993 2004
4. L.C. Scherrer D. Picard E. Massa J.M. Harmon S.S. Simons K.R. Yamamoto W.B. Pratt Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90 Biochemistry 32 1993 5381 5386
5. E.R. Sanchez M. Hirst L.C. Scherrer H.-Y. Tang M.J. Welsh J.M. Harmon S.S. Simons G.M. Ringold W.B. Pratt Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90 J. Biol. Chem. 265 1990 20123 20130
6. E.E. Diehl T.J. Schmidt Heat shock protein 70 is associated in substoichiometric amounts with the rat hepatic glucocorticoid receptor Biochemistry 32 1993 13510 13515
7. G. Srinivasan N.T. Patel E.B. Thompson Heat shock protein is tightly associated with the recombinant human glucocorticoid receptor:glucocorticoid response element complex Molec. Endocr. 8 1994 189 196
8. M. Rexin W. Busch U. Gehring Protein components of the nonactivated glucocorticoid receptor J. Biol. Chem. 266 1991 24601 24605
9. M.N. Alexis I. Mavridou D.J. Mitsiou Subunit composition of the untransformed glucocorticoid receptor in the cytosol and in the cell Eur. J. Biochem. 204 1992 75 84
10. P. Rehberger M. Rexin U. Gehring Heterotetrameric structure of the human progesterone receptor 10th Edn. Proc. Natn. Acad. Sci. U.S.A. 89 1992 8001 8005
11. B. Segnitz U. Gehring Subunit structure of the nonactivated human estrogen receptor 10th Edn. Proc. Natn. Acad. Sci. U.S.A. 92 1995 2179 2183
12. U. Gehring Structure of the nonactivated glucocorticoid receptor and activation to DNA binding B. Gametchu Glucocorticoid Receptor Structure and Leukemic Cell Responses 1995 Molecular Biology Intelligence Unit, R. G. Landes Co Austin 33 56
13. D.F. Smith D.O. Toft Steroid receptors and their associated proteins Molec. Endocr. 7 1993 4 11
14. W.B. Pratt The role of heat shock proteins in regulating the function folding and trafficking of the glucocorticoid receptor J. Biol. Chem. 268 1993 21455 21458
15. E.H. Bresnick F.C. Dalman E.R. Sanchez W.B. Pratt Evidence that the 90-kDa heat shock protein is necessary for the steroid binding conformation of the L cell glucocorticoid receptor J. Biol. Chem. 264 1989 4992 4997
16. T. Nemoto Y. Ohara-Nemoto M. Denis J.-A. Gustafsson The transformed glucocorticoid receptor has a lower steroid-binding affinity than the nontransformed receptor Biochemistry 29 1990 1880 1886
17. W.B. Pratt D.J. Jolly D.V. Pratt S.M. Hollenberg V. Giguere F.M. Cadepond G. Schweizer-Groyer M.G. Catelli R.M. Evans E.-E. Baulieu A region in the steroid binding domain determines formation of the non-DNA-binding, 9S glucocorticoid receptor complex J. Biol. Chem. 263 1988 267 273
18. r = 90,000 heat shock protein with the steroid binding domain of the glucocorticoid receptor J. Biol. Chem. 263 1988 18520 18523
19. F. Cadepond G. Schweizer-Groyer I. Segard-Maurel N. Jibard S.M. Hollenberg V. Giguere R.M. Evans E.-E. Baulieu Heat shock protein 90 as a critical factor in maintaining glucocorticosteroid receptor in a nonfunctional state J. Biol. Chem. 266 1991 5834 5841
20. L.C. Scherrer F.C. Dalman E. Massa S. Meshinchi W.B. Pratt Structural and functional reconstitution of the glucocorticoid receptor-hsp90 complex J. Biol. Chem. 263 1990 21397 21400
21. D.F. Smith B.A. Stensgaard W.J. Welch D.O. Toft Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events J. Biol. Chem. 267 1992 1350 1356
22. K.A. Hutchison M.J. Czar L.C. Scherrer W.B. Pratt Monovalent cation selectivity for ATP-dependent association of the glucocorticoid receptor with hsp70 and hsp90 J. Biol. Chem. 267 1992 14047 14053
23. K.A. Hutchison K.D. Dittmar M.J. Czar W.B. Pratt Proof that hsp70 is required for assembly of the glucocorticoid receptor heterocomplex with hsp90 J. Biol. Chem. 269 1994 5043 5049
24. E.R. Sanchez L.E. Faber W.J. Henzel W.B. Pratt The 56–59 kDa protein identified in untransformed steroid receptor complexes is a unique protein that exists in cytosol in a complex with both the 70 kDa and 90 kDa heat shock proteins Biochemistry 29 1990 5145 5152
25. r of 63,000, 56,000 and 50,000 J. Biol. Chem. 266 1991 6708 6713
26. R.J. Schumacher R. Hurst W.P. Sullivan N.J. McMahon D.O. Toft R.L. Matts ATP-dependent chaperoning activity of reticulocyte lysate J. Biol. Chem. 269 1994 9493 9499
27. K.A. Hutchison K.D. Dittmar W.B. Pratt All of the factors required for assembly of the glucocorticoid receptor into a functional heterocomplex with hsp90 are preassociated in a self-sufficient protein folding structure — a “foldosome” J. Biol. Chem. 269 1994 27894 27899
28. L.F. Stancato K.A. Hutchison P. Krishna W.B. Pratt Animal and plant cell lysates share a conserved chaperone system that assembles the glucocorticoid receptor into a functional heterocomplex with hsp90 Biochemistry 35 1996 554 561
29. M.-J. Gething J. Sambrook Protein folding in the cell Nature 355 1992 33 45
30. D.A. Parsell S. Lindquist The function of heat-shock proteins in stress tolerance: degradation and reactivation of damaged proteins Annu. Rev. Genet. 27 1993 437 496
31. D.F. Smith Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes Molec. Endocr. 7 1993 1418 1429
32. v-src and hsp90 is stabilized by molybdate, tungstate, and an endogenous cytosolic metal J. Biol. Chem. 267 1992 13952 13957
33. P. Csermely J. Kajtar M. Hollosi G. Jalsovszky S. Holly C.R. Kahn P. Gergely C. Soti K. Mihaly J. Somogy ATP induces a conformational change of the 90-kDa heat shock protein (hsp90) J. Biol. Chem. 268 1993 1901 1907
34. Y. Shi J.O. Thomas The transport of proteins into the nucleus requires the 70-kilodalton heat shock protein or its cytosolic cognate Molec. Cell. Biol. 12 1992 2186 2192
35. J. Yang D.B. DeFranco Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen Molec. Cell. Biol. 14 1994 5088 5098