Synthesis of 2'-aminomethyl derivatives of N-(2- (phosphonomethoxy)ethyl) nucleotide analogues as potential antiviral agents

Journal of Medicinal Chemistry

Volumn 39, Issue 17, 1996, Pages 3263-3268

  Dvořáková, Hana ^a   Masojídková, Milena ^a   Holý, Antonín ^a   Balzarini, Jan ^b   Andrei, Graciela ^b   Snoeck, Robert ^b   De Clercq, Erik ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

9 [3 AMINO 2 (PHOSPHONOMETHOXY)PROPYL]ADENINE; ANTIVIRUS AGENT; NUCLEOTIDE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN 3T3; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOMEGALOVIRUS; DRUG SYNTHESIS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; MOLONEY MURINE SARCOMA ONCOVIRUS; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; VACCINIA VIRUS; VARICELLA ZOSTER VIRUS; VIRUS INHIBITION;

3T3 CELLS; ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CYTOMEGALOVIRUS; HERPESVIRUS 1, HUMAN; HERPESVIRUS 2, HUMAN; HERPESVIRUS 3, HUMAN; HIV-1; HIV-2; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; MOLONEY MURINE SARCOMA VIRUS; PHOSPHONIC ACIDS; PURINE NUCLEOTIDES; PYRIMIDINE NUCLEOTIDES; SPECTROMETRY, MASS, FAST ATOM BOMBARDMENT; STRUCTURE-ACTIVITY RELATIONSHIP; VACCINIA VIRUS;

EID: 0029744987     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9601314     Document Type: Article

References (22)

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