Linkage Disequilibrium Analysis of G-olfα (GNAL) in Bipolar Affective Disorder

American Journal of Medical Genetics - Seminars in Medical Genetics

Volumn 67, Issue 5, 1996, Pages 491-494

  Tsiouris, S J ^a   Breschel, T S ^a   Xu, J ^a   McInns, M ^a   McMahon, F J ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Meyer 3 181 ^*  (United States)

Author keywords

Bipolar I; G proteins; Genetics; Mood disorder; Transmission Disequilibrium Test (TDT)

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; ARTICLE; CHROMOSOME 18; CONTROLLED STUDY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC SUSCEPTIBILITY; HUMAN; INHERITANCE; MAJOR CLINICAL STUDY; MANIC DEPRESSIVE PSYCHOSIS; ONSET AGE; PRIORITY JOURNAL; SIBLING;

ALLELES; BIPOLAR DISORDER; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 18; DINUCLEOTIDE REPEATS; FEMALE; GENE FREQUENCY; GTP-BINDING PROTEINS; HUMANS; LINKAGE DISEQUILIBRIUM; MACROMOLECULAR SUBSTANCES; MALE; NUCLEAR FAMILY; POLYMORPHISM, GENETIC;

EID: 0029743717     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19960920)67:5<491::AID-AJMG11>3.0.CO;2-I     Document Type: Article

References (24)

1. Ala-Kokko L (1995): Genome Data Base. Internet: gdbwww.gdb.org.
2. u: Tissue specific expression as mRNA with variable length 3′-non-translated regions. Third International Workshop on Human Chromosome 18 Mapping (Abstract).
3. Berrettini WH, Ferraro TN, Goldin LR, Weeks DE, Servilla D, Nurnberger JI, Gershon ES (1994): Chromosome 18 DNA markers and manic-depressive illness: Evidence for a susceptibility gene. Proc Natl Acad Sci USA 91:5918-5921.
4. Carli M, Anand-Srivastava MB, Molina-Holgado E, Dewar KM, Reader TA (1994): Effects of chronic lithium treatments on central dopaminergic receptor systems: G proteins as possible targets. Neurochem Int 24:13-22.
5. Copeman JB, Cucca F, Hearne CM, Cornall RJ, Reed PW, Ronningen KS, Undlien DE, Nisticò L, Buzzetti R, Tosi R, Pociot F, Nerup J, Cornélis F, Barnett AH, Bain SC, Todd JA (1995): Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33. Nat Genet 9:80-85.
6. Crowe RR (1993): Candidate genes in psychiatry: An epidemiological perspective. Am J Med Genet 48:74-77.
7. Endicott J, Spitzer RL (1978): A diagnostic interview: The Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 35:837-844.
8. Herve D, Levi-Strauss M, Marey-Semper I, Verney C, Tassin JP, Glowinski J, Girault JA (1993): G(olf) and gs in rat basal ganglia: Possible involvement of g(olf) in the coupling of dopamine d1 receptor with adenylyl cyclase. J Neurosci 13:2237-2248.
9. Jorde LB (1995): Invited editorial: Linkage disequilibrium as a genemapping tool. Am J Hum Genet 56:11-14.
10. Jorde LB, Watkins WS, Viskochil D, O'Connell P, Ward K (1993): Linkage disequlibrium in the neurofibromatosis I (NFI) region: Implications for gene mapping. Am J Hum Genet 53:1038-1050.
11. Kidd KK (1993): Associations of disease with genetic markers: Déjà vu all over again. Am J Med Genet 48:71-73.
12. Kruglyak L, Lander ES (1995): High-resolution genetic mapping of complex traits. Am J Hum Genet 56:1212-1223.
13. Lander ES, Schork NJ (1994): Genetic dissection of complex traits. Science 265:2037-2048.
14. Manji HK, Chen G, Shimon H, Hsiao JK, Potter WZ, Belmaker RH (1995): Guanine nucleotide-binding proteins in bipolar affective disorder: Effects of long-term lithium treatment. Arch Gen Psychiatry 52:135-144.
15. Risch N (1990): Linkage strategies for genetically complex traits. Am J Hum Genet 46:229-241.
16. Schaid DJ, Sommer SS (1994): Comparison of statistics for candidate-gene association studies using cases and parents. Am J Hum Genet 55:402-409.
17. Schlesselman JJ (1982): "Case-Control Studies." New York: Oxford University Press, p 162.
18. Simpson SG, Folstein SE, Meyers DA, DePaulo JR (1992): The assessment of lineality in bipolar I linkage studies. Am J Psychiatry 149:1660-1665.
19. Spielman RS, McGinnis RE, Ewens WJ (1993): Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM). Am J HumGenet 52:506-516.
20. Spitzer RL, Endicott J, Robins E (1975): "Research Diagnostic Criteria for a Selected Group of Functional Disorders." New York: Biometrics Research.
21. Stine OC, Xu J, Koskela R, McMahon FJ, Gschwend M, Friddle C, Clark CD, McInnis M, Simpson SG, Breschel TS, Vishio E, Riskin K, Feilotter H, Chen E, Shen S, Folstein S, Meyers DA, Botstein D, Marr TG, DePaulo JR (1995): Evidence for linkage of bipolar disorder to chromosome 18 with a parent-of-origin effect. Am J Hum Genet 57:1384-1394.
22. Terwilliger JD (1995): A powerful likelihood method for the analysis of linkage disequilibrium between trait loci and one or more poly-morphic marker loci. Am J Hum Genet 56:777-787.
23. Thomson G (1995): Mapping disease genes: Family-based association studies. Am J Hum Genet 57:487-498.
24. Young A (1995): "Genetic Analysis System," 1.4. ftp: well.ox.ac.uk.