Electrodynamics of microtubular motors: The building blocks of a new model

BioSystems

Volumn 39, Issue 3, 1996, Pages 187-226

  Insinna, Ezio M ^a   Zaborski, Patrick ^b   Tuszynski, Jack ^c  

^a Bioelectronics Research Association   (France)

^b CNRS   (France)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

ATPase activation; Ciliary beating; Conformational changes; Cytoskeleton; Electron transfer; Euglena gracilis; Intracellular transport; Microtubules; Protozoan; Vertebrate photoreceptors

Indexed keywords

ADENOSINE TRIPHOSPHATASE;

ARTICLE; CILIARY MOTILITY; COMPUTER SIMULATION; CYTOSKELETON; ELECTRON TRANSPORT; ELECTROPHYSIOLOGY; EUGLENA GRACILIS; INTRACELLULAR TRANSPORT; MICROTUBULE; MODEL; NONHUMAN; PHOTORECEPTOR; PROTOZOON; VERTEBRATE;

EUGLENA GRACILIS; PROTOZOA; VERTEBRATA;

EID: 0029743120     PISSN: 03032647     EISSN: None     Source Type: Journal    
DOI: 10.1016/0303-2647(96)01616-4     Document Type: Article

References (216)

1. Allen, R.D., 1978, Particle arrays in the surface membrane of Paramecium: junctional and possible sensory sites. J. Ultrastruct. Res. 63, 64-78.
2. Allen, R.D. et al., 1985a, Gliding movement of and bidirectional transport along single native microtubules from squid axoplasm: evidence for active role of microtubules in cytoplasmic transport. J. Cell Biol. 100, 1736-1752.
3. Allen, R.D. et al., 1985b, The dynamic microtubules theory of axonal and cytoplasmic transport, and a hypothesis regarding the mechanism. Microtubules and microtubules inhibitors. M. De Brabander and J. De Mey (eds.) Elsevier, Amsterdam.
4. Amos, L.A. et al., 1976, Molecular structure of flagella microtubules, in: Cell Motility, R. Goldman, T. Pollard and J. Rosenbaum (eds.) Cold Spring Harbor Laboratory, pp. 847-868.
5. Amos, L.A., 1979, Structure of microtubules, in: Microtubules, K. Roberts and J.S. Hyams (eds.) Academic Press, London.
6. Amos, L.A., 1982, Tubulin and associated proteins, in: Electron Microscopy of Proteins, Vol. 3, I.R. Harris (ed.) Academic Press. London-N.Y., pp. 207-250.
7. Anderson, R.G.W. and Hein, C.E., 1977, Distribution of anionic sites on the oviduct ciliary membrane. J. Cell Biol. 72, 482-492.
8. Arikawa, K. and Williams, D.S., 1989, Organization of actin filaments and immunocolocalization of α-actinin in the connecting cilium of rat photoreceptors. J. Comp. Neurol. 288, 640-646.
9. Athenstaedt, H., 1974, Pyroelectric and piezoelectric properties of vertebrates. Ann. Acad. Sci. 238, 68-94.
10. Bancroft, F.W., 1913, Heliotropism, differential sensibility and galvanotropism in Euglena. J. Exp. Zool. 15, 383-428.
11. Barber, V.C., 1974, Cilia in sense organs, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press, London.
12. Bershadsky, A.D. and Vasiliev, J.M., 1988, Cytoskeleton Plenum Press, N.Y.
13. Besharse, J.C., 1986, Photosensitive membrane turnover: differentiated membrane domains and cell-cell interaction, in: The Retina: a Model for Cell Biological Studies. Part I. R. Adler and D. Farber (eds.) Academic Press, N.Y., pp. 297-352.
14. Besharse, J.C., and Pfenninger, K.H., 1980, Membrane assembly in retinal photoreceptors. I. Freeze fracture analysis of cytoplasmic vesicles in relationship to disc assembly. J. Cell Biol. 87, 451-463.
15. Besharse, J.C. et al., 1985, Membrane assembly in retinal photoreceptors. III. Distinct membrane domains of the connecting cilium of developing rods. J. Neurosci. 5, 1035-1048.
16. Besharse, J.C. and Horst, C., 1990, The photoreceptor connecting cilium. In: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.) Plenum Press, N.Y.
17. 2+ and cyclic nucleotides. Adv. Second Messenger and Phosphoprotein Res. 23, 227-272.
18. Bouck, G.B. et al., 1990, Euglena gracilis: a model for flagellar surface assembly, with reference to other cells that bear flagellar mastigonemes scales. In: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.) Plenum Press, N.Y.
19. Bovee, E.C. and Jahn, T.L., 1972, A theory of piezoelectric-activity and ion-movements in the relation of flagellar structures and their movements to the phototaxis of Euglena. J. Theor Biol. 35, 259-273.
20. Brady, S.T., 1985, A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317, 73-75.
21. Brady et al., 1990, A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proc. Natl. Acad. Sci. USA 87, 1061-1065.
22. Broekhuyse, R.M., et al., 1985, Light induced shift and binding of S-antigen in retinal rods. Curr. Eye Res. 4, 613-618.
23. Brokaw, C.J., 1974, Movement of the flagellum of some marine invertebrate spermatozoa. In: Cilia and Flagella, M.A. Sleigh, (ed.) Academic Press.
24. Brokaw, C.J. et al., 1982, Analysis of the movement of Chlamidomonas flagella. III. The function of the radial spoke system is revealed by comparison of wild-type and mutant flagella. J. Cell Biol. 92, 722-732.
25. Brokaw, C.J. and Luck, D.J.L., 1985, Bending patterns of Chlamidomonas flagella. III. A radial spoke head deficient mutant and a central pair deficient mutant. Cell Motil. 5, 195-208.
26. Brokaw, C.J. and Kamiya, R., 1987, Bending patterns of Chlamidomonas flagella: IV. Mutants with defects in inner and outer dynein arms indicate differences in dynein arm function. Cell Motil. 8, 68-75.
27. Buetow, D.E., 1968a, The Biology of Euglena. Vol. I, Academic Press, N.Y.
28. Buetow, D.E., 1968b, The Biology of Euglena. Vol. II, Academic Press, N.Y.
29. Buetow, D.E., 1982, The Biology of Euglena. Vol. III, Academic Press, N.Y.
30. Buetow, D.E., 1989, The Biology of Euglena. Vol. IV, Academic Press, N.Y.
31. Chailley, B. et al., 1990, Structure and assembly of the oviduct ciliary membrane, in: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.).
32. Chaitin, M.H., 1992, Double immunogold localization of opsin and actin in the cilium of developing mouse photoreceptors. Exp. Eye Res. 54, 261-267.
33. Chou, K.-C. Zhang, C-T. and Maggiora, G.M., 1994, Solitary wave dynamics as a mechanism for explaining the internal motion during microtubule growth. Biopolymers, 34, 143.
34. Chrétien, D. and Wade, R.H., 1991, New data on the microtubule surface lattice. Biol. Cell 71. 161-174.
35. Cleveland, D.W. 1982, Treadmilling of tubulin and actin. Cell 28, 689-691.
36. Cohen, A.I., 1972, Rods and cones, in: Handbook of Sensory Physiology-Vol. VII/2-Physiology of Photoreceptor Organs. Fuortes, M.G.F. ed. Springer, Berlin.
37. Cope, F.W., 1974, Solid state physical mechanism of biological energy transduction. Ann. NY Acad. Sci., 227, 74-97.
38. Crescitelli, F., 1972, The visual cells and visual pigments of the vertebrate eye, in: Handbook of Sensory Physiology, Vol. VII/1 - Photochemistry of Vision, H.J.A. Dartnall (ed.) Springer Verlag, Berlin.
39. David-Pfeuty, T. et al., 1977, GTPase activity of tubulin associated with microtubule assembly. Proc. Natl. Acad. Sci. USA 74, 5372-5376.
40. Davydov, A.S., 1982, The migration of energy and electrons in biological systems, in: Biology and Quantum Mechanics, A.V. Holden and B. Winlow (eds.) Springer Verlag, Berlin.
41. Dentler, W.L., 1977, Fine structural localization of phospatases in cilia and basal bodies of Tetrahymena pyriformis. Tissue Cell 9, 209-222.
42. Dentler, W.L., 1981, Microtubule-membrane interactions in cilia and flagella. Int. Rev. Cytol. 72, 1-47.
43. Dentler, W.L., 1986, Isolation of capped cilia from bovine trachea and the effect of caps on microtubule assembly in vitro. J. Cell Biol. 103, 279a.
44. Dentler, W.L., 1987, Cilia and flagella. Int. Rev. Cytol. Suppl. 17, 391-456.
45. Dentler, W.L., 1990, Microtubule-membrane interactions, in: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.) N.Y., Plenum Press.
46. Dentler, W.L. and Rosenbaum, J.L., 1977, Flagellar elongation and shortening in Chlamydomonas. III. Structures attached to the tips of flagellar microtubules and their relationship to the directionality of microtubule assembly. J. Cell Biol. 74, 747-759.
47. Dentler, W.L. et al., 1980, Microtubule-membrane interactions in cilia. II. Photochemical crosslinking of bridge structures and the identification of a membrane-associated ATPase. J. Cell Biol. 84, 381-403.
48. Dentler, W.L. and Le Cluyse, E.L., 1982, The effects of structures attached to the tips of tracheal ciliary microtubules on the nucleation of microtubules assembly in vitro. Cell Motil. Suppl. 1, 13-18.
49. De Robertis, E. and Lasansky, A., 1961, Ultrastructure and chemical organization of photoreceptors, in: The Structure of the Eye. Academic Press, N.Y.
50. DeVault, D., 1984, Quantum-Mechanical Tunnelling in Biological Systems. Cambridge Univ. Press.
51. DeVault, D. et al., 1967, Electron tunnelling in cytochromes. Nature, Lond. 215, 642-644.
52. Dirksen, E.R. and Satir, P., 1972, Ciliary activity in the mouse oviduct as studied by transmission and scanning electron microscopy. Tissue Cell 4, 389-404
53. Duhaiman, A.S and Bamburg, J.R., 1984, Isolation of brain α-actinin: its characterization and a comparison of its properties with those of muscle α-actinins. Biochemistry 23, 1600-1608.
54. Dustin, P., 1984, Microtubules. Springer, Berlin-N.Y.
55. Dute, R. and Kung, C., 1978, Ultrastructure of the proximal region of somatic cilia in Paramecium tetraurelia, J. Cell Biol. 78, 451-464.
56. Eakin, R.M., 1968, Evolution of photoreceptors, in: Evolutionary Biology, Vol. II. T. Dobzhanski, M.K. Hecht, W.C. Steere (eds.), Appleton-Century-Crofts, N.Y.
57. Eakin, R.M., 1972, Structure of Invertebrate Photoreceptors, in: Handbook of Sensory Physiology, Vol. VII/1. H.J.A. Dartnall (ed.) Springer Verlag, Berlin.
58. Eckert, R., 1972, Bioelectric control of ciliary activity. Science, 176, 473-481.
59. Engelmann, T.W., 1882. Ueber Licht-und Farbenperception niederster Organismen. Pflügers Arch. 29, 387-400.
60. Feileib, M.E. and Curry, G.M., 1971, The nature of the photoreceptor in phototaxis, in: Handbook of Sensory Physiology, Vol. I. Springer Verlag, Berlin.
61. Feileib, M.E., 1985, Behavioural studies of free-swimming photoresponsive organisms, in: Sensory Perception and Transduction in Aneural Organisms, G. Colombetti et al. (eds.) Plenum Press, N.Y.
62. Fesenko, E.E. et al., 1985, Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment. Nature 313, 310-313.
63. Fröhlich, H., 1968, Long-range coherence and energy storage in biological systems. Int. J. Quantum Chem. 2, 641-649.
64. Fröhlich, H., 1970, Long range coherence and the action of enzymes. Nature, 228, 1093.
65. Fröhlich, H., 1975a, The extraordinary dielectric properties of biological materials and the action of enzymes. Proc. Natl. Acad. Sci. USA 72, 4211-4215.
66. Fröhlich, H., 1975b, Evidence for Bose condensation-like excitations of coherent modes in biological systems. Phys. Letters, Vol. 51, A-1.
67. Fuertes, M.G.F. and O'Bryan, P.M., 1972, Generator potential in invertebrate photoreceptors, in: Handbook of Sensory Physiology - Vol. VII/2 - Physiology of Photoreceptor Organs. M.G.F. Fuorte (ed.) Springer, Berlin. pp. 279-321.
68. Gibbons, I.R., 1981, Cilia and flagella of eukaryotes. J. Cell Biol. 91, 107s-124s.
69. Gibbons, I.R. et al., 1976, Multiple forms of dynein in sea urchin sperm flagella, in: Cell Motility, R. Goldman, T. Pollard and J. Rosenbaum (eds.) Cold Spring Harbor Laboratory, pp. 847-868.
70. Gibbons, I.R., 1988, Dynein ATPases as microtubule motors. J. Biol. Chem., 263, 15837-15840.
71. Goldman, R. et al., 1976, Cell Motility, R. Goldman, T. Pollard and J. Rosenbaum (eds.) Cold Spring Harbor Laboratory.
72. Goldstein, S.F., 1974, Isolated, reactivated and laser-irradiated cilia and flagella, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press.
73. Gualtieri, P. et al., 1986, Isolation of the photoreceptor (paraflagellar body) of the phototactic flagellate Euglena gracilis. Arch. Microbiol. 145, 303-305.
74. Gualtieri, P. et al., 1989, Absorption spectrum of a single isolated paraflagellar swelling of Euglena gracilis. Biochim. Biophys. Acta. 993, 293-296.
75. Gualtieri, P. et al., 1990, A look into the reservoir of Euglena gracilis: S.E.M. investigations of the flagellar apparatus. Micron Microsc. Acta, 21, 131-138
76. Gualtieri, P. et al., 1992, Identification of a rhodopsin photoreceptor in Euglena gracilis. Biochim. Biophys. Acta, 1117, 55-59.
77. Hagins, W.A. et al., 1970, Dark current and photocurrent in retinal rods. Biophys. J. 10, 380-412.
78. Halldal, P., 1957, Importance of calcium and magnesium ions in phototaxis of motile green algae. Nature 179, 215-216.
79. Halldal, P., 1959, Factors affecting light response in phototactic algae. Physiol. Plant. 12, 742-752.
80. Hameroff, S. R., 1987, 'Ultimate Computing: Biomolecular Consciousness and Nanotechnology'. Elsevier - North Holland, Amsterdam.
81. Hameroff, S.R., Watt, R.C., 1982, Information processing in microtubules. J. Theor. Biol. 98, 549-561.
82. Hameroff, S.R., Smith, S., Watt, R.C., 1984, Non-linear electrodynamics in cytoskeletal protein lattices, in: Nonlinear Electrodynamics in Biology and Medicine, F.A. Lawrence and W.R. Adey (ed.) Plenum Press. N.Y.
83. Hiramoto, Y., 1974, Mechanics of ciliary movement, in: Cilia and Flagella, M.A. Sleigh, (ed.), Academic Press.
84. Hirokawa, N. et al., 1991, Kinesin associates with anterogradely transported membranous organelles in vivo. J. Cell Biol. 114, 295-302.
85. Hirokawa, N., 1993, Axonal transport and the cytoskeleton. Curr. Opin. Neurobiol. 3, 724-731.
86. Hirose, K. et al., 1995, Nucleotide-dependent angular change in kinesin motor domain bound to tubulin. Nature 376, 277-279.
87. Hitt, A. et al., 1990, Microtubule solutions display nematic liquid crystalline structure. J. Biol. Chem. 265, 1639-1647.
88. Hoenger, A. et al., 1995, Three-dimensional structure of a tubulin-motor-protein complex. Nature 376, 271-274.
89. Hoops, H.J. and Witman, G.B., 1985, Basal bodies and associated structures are not required for normal flagellar motion or photaxis in the green alga Chorogonium elongatum. J. Cell Biol. 100, 297-309.
90. Holwill, M.E.J., 1974, Hydrodynamic aspects of ciliary and flagellar movement, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press.
91. Hopfield, J.J., 1974, Electron transfer between biological molecules by thermally activated tunnelling. Proc. Nat. Acad. Sci, USA. Vol. 71, No. 9, 3640-3644.
92. Horio, T. and Hotani, H., 1986, Visualisation of the dynamic instability of individual microtubules by darkfield microscopy. Nature (Lond.) 321, 605-607.
93. Huang, B.P.-H., 1986, Chlamydomonas Reinhardtii: a model system for the genetic analysis of flagellar structure and motility. Int. Rev. Cytol. 99, 181-215.
94. Huitorel, P. and Kirschner, M.W., 1988, The polarity and stability of microtubule capture by the kinetochore. J. Cell Biol. 106, 151-159.
95. Hyams, J.S., 1982, The Euglena paraflagellar rod: structure, relationship to the other flagellar components and preliminary biochemical characterization. J. Cell Sci. 55, 199-210.
96. Insinna, E.M., 1989, Jungian Synchronicity and Biological Morphogenesis. An Application to the Study of Microtubules. Ph.D. Thesis, Université Paris X, Nanterre. ISSN: 0294-1767.
97. Ishijima, S. et al., 1988, Comparative study of the beat patterns of American and Asian horseshoe crab sperm: evidence for a role of the central pair complex in forming planar waveforms in flagella. Cell Motil. 9, 264-270.
98. Jarosch, R. and and Fuchs, B., 1975, Zur Fibrillenrotation in der Synura-Geissel, Protoplasma 85, 285-290.
99. Jennings, H.S., 1906, Behavior of the Lower Organisms. N.Y. Columbia University Press.
100. Jockush, B.M. and Isenberg, G., 1981, Interaction of α-actinin and vinculin with actin: opposite effects on filament network formation. Proc. Natl. Acad. Sci. USA 78, 3005-3009.
101. Kamiya, R., 1982, Extension and rotation of the central-pair microtubules in detergent-treated Chlamydomonas flagella. Cell Motil. Suppl. 5, 169-173.
102. Kamiya, R. et al., 1982, Rotation of the central pair microtubules in Chlamydomonas flagella, in: Biological Functions of Microtubules and Related Structures. H. Sakai, H. Mohri and G.G. Borisy (eds.) Academic Press, N.Y., pp. 189-198.
103. Kikkawa, M. et al., 1994, Direct visualization of the microtubule lattice seam both in vitro and in vivo. J. Cell Biol. 127, 1965-1971.
104. Kimball, J.C., 1980, Kinks, solitons and nonlinear transport in solids. Phys. Rev. B21, 2104-2107.
105. Kirchner, K and Mandelkow, E., 1985, EMBO J. 4, 2397-2402.
106. Kirschner, M.W. 1978, Microtubule assembly and nucleation. Int. Rev. Cytol. 54, 1-71.
107. Kirschner, M.W. 1980, Implication of treadmilling for the stability and polarity of actin and tubulin polymers in vivo. J. Cell Biol. 86, 330-334.
108. Kitanishi-Yumura, T. and Fukui, Y., 1987, Re-organisation of microtubules during mitosis in Dyctyostelium: dissociation from MTOC and selective assembly/disassembly in situ. Cell Motil. 8, 106-117.
109. Koruga, D., 1990, Semiconductor and crystal symmetry assessment of microtubule proteins as molecular machines. J. Mol. Electron., Vol. 6, 167-173.
110. Kuhn, C. and Engleman, W., 1978, The structure of the tips of mammalian respiratory cilia. Cell Tissue Res. 186, 491-498.
111. Leedale, G.F., 1967, The Euglenoid Flagellates. Englewood Cliffs, N.J. Prentice Hall.
112. Linck, R.W. and Langevin, G.L., 1981, Reassembly of flagellar B (ab) tubulin into singlet microtubules: consequences for cytoplasmic microtubule structure and assembly. J. Cell Biol. 89, 323-337.
113. Linck, R.W. et al., 1981, Arrangement of tubulin subunits and microtubule-associated proteins in the central-pair microtubule apparatus of squid (Loligo pealei) sperm flagella. J. Cell Biol. 89, 309-322.
114. Luck, D.J.L., 1984, Genetic and biochemical dissection of the eukaryotic flagellum. J. Cell Biol. 98, 789-794.
115. Luduena, R.F., 1979, Biochemistry of tubulin, in Microtubules, K. Roberts and J.S. Hyams (eds.) Academic Press, London.
116. Machemer, H., 1974, Ciliary activity and metachronism in Protozoa, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press.
117. Machemer, H., 1986, Electromotor coupling in cilia, in: Membrane Control of Cellular Activity, Vol. 33. C. Luttgau (ed.) Fortschritte der Zoologie, Fischer Verlag, Stuttgart, pp. 205-250.
118. Machemer, H. and Ogura, A., 1979, Ionic conductances of membranes in ciliary and deciliated Paramecium. J. Physiol. 296, 49-60.
119. Mandelkow, E.-M and Mandelkow, E., 1992, Microtubule oscillations. Cell Motil. Cytoskel. 22, 235-244.
120. Mandelkow, E. et al., 1985, Domains, antigenicity and substructure of tubulin, in: Microtubules and Microtubules Inhibitors, M. De Brabander and J. De Mey (eds.) Elsevier, Amsterdam.
121. Mandelkow et al., 1986, On the surface lattice of microtubules: helix starts, protofilament number, seam and handedness. J. Cell Biol. 102, 1067-1073.
122. Mandelkow, E. et al., 1989, Spatial patterns from oscillating microtubules. Science, 246, 1291-1293.
123. Marchese-Ragona, S.P. and Johnson, 1985, Localization of 14S and 22S dyneis in Tetrahymena cilia. J. Cell Biol. 101, 278a.
124. Marcus, R.A. and Sutin, N., 1985, Electron transfers in chemistry and biology. Biochim. Biophys. Acta, 811, 265-322.
125. Margolis, R.L. and Wilson, L., 1981, Microtubule treadmills - possible molecular machinery. Nature 293, 705-711.
126. Mast, S.O., 1911, Light and the Behavior of Organisms. N.Y. John Wiley and Sons.
127. Mast, S.O., 1914, Orientation in Euglena with some remarks on tropism. Biol. Zbl. 34, 641-664.
128. Mast, S.O., 1917, The relation between spectral color and stimulation in the lower organisms. J. Exp. Zool. 22, 471-528.
129. McNaughton, P.A., 1990, Light response of vertebrate photoreceptors. Physiol. Rev., 70, 847-883.
130. Miller, J.R., 1975, Reactions of trapped electrons by quantum mechanical tunnelling observed by pulse radiolysis of an aqueous glass. J. Phys. Chem. 79, 1070-1078.
131. Mitchison, T. and Kirschner, M., 1984, Dynamic instability of microtubules growth. Nature 312, 237-242.
132. Mitchison, T. et al., 1986, Sites of microtubule assembly and disassembly in the mitotic spindle. Cell, 45, 115-527.
133. Mogesen, M.M. and Tucker, J.B., 1987, Evidence for microtubule nucleation at plasma membrane-associated sites in Drosophila. J. Cell Sci., 88, 95-107.
134. Mogesen, M.M. et al., 1989, Microtubule polarities indicate that nucleation and capture of microtubules occurs at cell surfaces in Drosophila. J. Cell Biol. 108, 1445-1452.
135. Moestrup, O., 1982, Flagellar structure in algae: a review, with new observations particularly on the Crysophyceae, Phaenophyceae (Fucophyceae), Euglenophyceae and Reckertia. Phycologica, 21, 427-528.
136. Murray, J.M., 1984, Three-dimensional structure of a membrane-microtubule complex. J. Cell Biol. 98, 283-295.
137. Musgrave, A., et al., 1986, Evidence for a functional membrane barrier in the transition zone between the flagellum and the cell body of Chlamydomonas eugametos gametes. Planta 167, 544-553.
138. Naitoh, Y. and Eckert, R., 1969, Ionic mechanisms controlling behavioral responses of Paramecium to mechanical stimulation. Science 164, 963-965.
139. Naitoh, Y. and Eckert, R., 1974, The control of ciliary activity in Protozoa, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press.
140. Nangaku, M., 1994, KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria. Cell 79, 1209-1220.
141. Niclas, J. et al., 1994, Cloning and localization of a conventional kinesin motor expressed exclusively in neurons. Neuron 21, 1059-1072.
142. Nojima, D. et al., 1995, At least one of the protofilamnets in flagellar microtubules is not composed of tubulin. Curr. Biol. 5, 158-167.
143. Norwood, J.T. et al., 1978, Polycationic macromolecules inhibit cilia-mediated ovum transport in the rabbit oviduct. Proc. Natl. Acad. Sci. USA 75, 4413-4416.
144. Norwood, J.T. and Anderson, R.G.W., 1980, Evidence that adhesive sites on the tips of oviduct cilia membranes are required for ovum pickup in situ. Biol. Reprod. 23, 788-791.
145. Ogura, A. and Machemer, H., 1980, Distribution of mechanoreceptor channels in the Paramecium surface membrane. J. Comp. Physiol. 135, 233-242.
146. O'Hara, P.T., 1970, Spiral tilt of triplet fibers in human leukocyte centrioles. J. Ultrastruct. Res. 31, 195-198.
147. Okada, Y. et al., 1995, The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors. Cell 81, 769-780.
148. Olmsted, J. B., 1986, Microtubule-associated proteins. Ann. Rev. Cell. Biol. 2, 421-457.
149. Omoto, C.K. and Kung, C., 1979, The pair of central tubules rotates during ciliary beat in Paramecium. Nature 279, 532-534.
150. Omoto, C.K. and Kung, C., 1980, Rotation and twist of the central-pair microtubules in the cilia of Paramecium. J. Cell Biol. 87, 33-46.
151. Osafune, T. and Schiff, J.A., 1980, Stigma and flagellar swelling in relation to light and carotenoids in Euglena gracilis var. Bacillaris. J. Ultrastruct. Res. 73, 336-349.
152. Papermaster, D.S. et al., 1975, Membrane biosynthesis in the retina: opsin transport in the photoreceptor cell. Biochemistry 14, 1343-1352.
153. Penn, R.D. and Hagins, W.A., 1972, Kinetics of the photocurrent of retinal rods. Biophys. J. 12, 1073-1094..
154. Penningroth, S. M. and Petersons. D.D., 1986, Evidence for functional differences between two flagellar dynein ATPases. Cell Motil. 6, 586-594.
155. Perry, R.J. and McNaughton, P.A., 1991, Response properties of cones from the retina of the Tiger salamander. J. Physiol. 433, 561-587.
156. + exchange in rods isolated from the Salamander retina. J. Physiol. 466, 443-480.
157. Pethig, R., 1979,, Dielectric and Electronic Properties of Biological Materials. Wiley, Chichester.
158. Pethig, R. and Szent-Györgyi, A., 1977, Electronic properties of the casein methylglyoxal complex. Proc. Nat. Acad. Sci, USA, 74, 226-228.
159. Piccinni, E. and Omodeo, P., 1975, Photoreceptors and phototactic programs in Protista. Boll. Zool. 42, 57-79.
160. Piccinni, E. et al., 1975, ATPase activity in flagella from Euglena gracilis. Localization of the enzyme and effects of detergents. J. Protozool. 22, 331-335.
161. Picinni, E. and Mammi, M., 1978, Motor apparatus of Euglena gracilis: ultrastructure of the basal portion of the flagellum and the para-flagellar body. Boll. Zool. 45, 405-414.
162. Pirner, M.A. and Linck, R.W., 1994, Tektins are heterodimeric polymers in flagellar microtubules with axial periodicities matching the tubulin lattice. J. Biol. Chem. 269, 31800-31806.
163. Portman, R.W. et al., 1987, Development of microtubule capping structures in ciliated epithelial cells. J. Cell Sci. 87 (Pt. 1), 85-94.
164. Preston, R.R. and Saimi, Y., 1990, Calcium ions and the regulation of motility in Paramecium, in: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.).
165. Rasmussen, S. et al., 1990, Computational connectionism within neurons: a model of cytoskeletal automata subserving neural networks. Physica D42, 428-449.
166. Roberts, K. and Hyams, J.S., 1979, Microtubules, Academic Press, London - N.Y.
167. Rosati, G. et al., 1991, Ultrastructure of the apical zone of Euglena gracilis: photoreceptors and motor apparatus. Electron Microsc. Rev. 4, 319-342.
168. Roth, L.E. et al., 1970, Microtubules in the Heliozoan Axopodium. I. The gradion hypothesis of allosterism in structural proteins. J. Ultrastr. Res., 30, 7-37.
169. Roth, L.E. and Pihlaja, D.J., 1977, Gradionation: hypothesis for positioning and patterning. J. Protozool., 24, 2-9.
170. Sale, W.S. and Satir, P., 1977, Direction of active sliding of microtubules in Tetrahymena cilia, Proc. Natl. Acad. Sci. USA 74, 2045-2049.
171. Sammak, P.J. et al., 1987, Mechanism of microtubules dynamics 'in vivo'. J. Cell Biol. 104, 402-405.
172. Sandoz, D., et al. 1979, Relationship between intramembrane particles and glycoconjugates in the ciliary membrane of the quail oviduct. Biol. Cell. 39, 267-279.
173. Sataric, M.V. et al., 1993, Kinklike excitations as an energy transfer mechanism in microtubules. Phys. Rev. E 48, 589.
174. Satir, P., 1968, Studies on cilia III. Further studies on the cilium tip and a 'sliding filament' model of ciliary motility. J. Cell Biol. 39, 77-94.
175. Scheele, R.B. and Borisy, G.G., 1979, In vitro assembly of microtubules, in: Microtubules, K. Roberts and J.S. Hyams (eds.) Academic Press, London.
176. Schmit, A-C. and Lambert, A-M., 1985, F-Actin is associated to microtubule function during cytokinesis in higher plants. A revised concept, in: Microtubules and Microtubule Inhibitors, M. De Brabander and J. De Mey (eds.) Elsevier, Amsterdam. pp. 243-246.
177. Schnapf, J.L. and Baylor, D.A., 1987, How photoreceptor cells respond to light. Sci. Am. 256, 40-47.
178. Selden, S.C. and Pollard, T.D., 1986, Interaction of actin filaments with microtubules is mediated by microtubule-associated-proteins and regulated by phosphorylation. Ann. N.Y. Acad. Sci. 466, 803-812.
179. Sleigh, M.A., 1974, Metachronism of cilia of Metazoa, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press.
180. Sneddon, S.F. et al., 1988, A new classification of the amino acid side chains based on doublet acceptor energy levels. Biophys. J., 53, 1.
181. Spiegelman, B.L. et al., 1977, Turnover of tubulin and the N-site GTP in CHO cells. Cell 12, 587-600.
182. Stebbings, H. and Hunt, C., 1982, The nature of the clear zone around microtubules. Cell Tiss. Res. 227, 609.
183. Steinberg, R.H., 1980, Disc morphogenesis in vertebrate photoreceptors. J. Comp. Neurol. 190, 501-518.
184. Stossel, T.P. et al., 1985, Non-muscle actin-binding proteins. Ann. Rev. Cell Biol. 1, 353-402.
185. Stryer, L., 1986, Cyclic GMP cascade of vision. Annu. Rev. Neurosci. 9, 87-119.
186. Surek, B. and Melkonian, M., 1986, A cryptic cytostome is present in Euglena. Protoplasma 133, 39-59.
187. Szent-Györgyi, A., 1941, Towards a new biochemistry. Science 93, 609-611.
188. Tabony, J. and Job, D., 1990, Spatial structures in microtubular solutions requiring a sustained energy source. Nature, Vol. 346, 448-451.
189. Tabony, J. and Job, D., 1992, Microtubular dissipative structures in biological auto-organization and pattern formation. Nanobiology, Vol. 1, Nr 2, 131, 147.
190. Taylor, G., 1952, The action of waving cylindrical tails in propelling microscopic organisms. Proc. Soc. A. 211, 225-239.
191. Tomita, T., 1971, Electrical activity of vertebrate photoreceptors. Q. Rev. Biophys. 3, 179-222.
192. Tucker, J.B., 1979, Spatial organization of microtubules, in: Microtubules, Roberts, K. and Hyams, J. S. (eds.) Academic Press, London.
193. Tucker, J.B., 1986, Centrosomal microtubule-organizing centres and a switch in the control of protofilament number for cell surface-associated microtubules during Drosophila wing morphogenesis. Eur. J. Cell Biol. 41, 279-289.
194. Tuszynski, J. A. et al., 1995, Ferroelectric behavior in microtubule dipole lattices: implications for information processing, signaling and assembly/disassembly. J. Theor. Biol. (1995) 174, 371-380.
195. Vale, R. D., 1987, Intracellular transport using microtubules-based motors. Ann. Rev. Cell. Biol. 3, 347-378.
196. Vale, R.D. and Toyoshima, Y.Y., 1988, Rotation and translocation of microtubules in vitro induced by dyneins from Tetrahymena cilia. Cell 52, 459-469.
197. Vale, R.D., 1993, Guidebook to the Cytoskeletal and Motor Proteins, Thomas, K. and Vale R. eds., 175-212. Oxford Univ. Press.
198. Vaughan, D.K. et al., 1989, Evidence that microtubules do not mediate opsin vesicle transport in photoreceptors. J. Cell Biol. 109, 3053-3062.
199. Vickerman, K. and Tetley, L., 1990, Flagellar surfaces of parasitic Protozoa and their role in attachment, in: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.).
200. Warner, F.D., 1974, The fine structure of the ciliary and flagellar axoneme, in: Cilia and Flagella, M.A. Sleigh (ed.) Academic Press, London, pp. 11-37.
201. Warner, F.D. and Satir, P., 1974, The structural basis of ciliary bend formation. radial spoke positional changes accompanying microtubule sliding. J. Cell Biol. 63, 35.
202. Warner, F.D., 1976, Cross-bridge mechanism in ciliary motility: the sliding-bending conversion, in: Cell Motility, R. Goldman, T. Pollard and J. Rosenbaum eds. Cold Spring Harbor Laboratory, pp. 891-914.
203. Warr, J.R. et al., 1966, Genetic control of flagellar structure in Chlamydomonas Reinhardtii. Genet. Res. 7, 335-351.
204. Watanabe, T., 1990, The role of ciliary surfaces in mating in Paramecium, in: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.).
205. Weisenberg, R.C., 1981, The role of nucleotide triphosphate in actin and tubulin assembly and function. Cell Motil. 1, 485-498.
206. Wheatley, D.N., 1982, The Centriole: A Central Enigma of Cell Biology. Elsevier, N.Y.
207. Willey, R.L. and Wibel, R.G., 1987, Flagellar roots and the reservoir cytoskeleton of Colacium libellae (Euglenophyceae). J. Phycol. 23, 283-288.
208. Williams, D.S. et al., 1988, Disruption of microfilaments organization and deregulation of disk membrane morphogenesis by cytokalasin D in rod and cone photoreceptors. J. Comp. Neurol. 272, 161-172.
209. Witman, G.B. et al., 1976, Chlamydomonas mutants: evidence for the roles of specific axonemal components in flagellar movement, in: Cell Motility, R. Goldman, T. Pollard and J.
210. Rosenbaum (eds.) Cold Spring Harbor Laboratory, pp. 969-986.
211. Witman, G.B. et al., 1978, Chlamydomonas flagellar mutants lacking radial spokes and central tubules. structure, composition and function of specific axonemal components. J. Cell Biol. 76, 729-747.
212. Witman, G.B., 1990, Introduction to cilia and flagella, in: Ciliary and Flagellar Membranes, R.A. Bloodgood (ed.).
213. Wolken, J.J., 1977, Euglena: the phoreceptor system for photoxasis. J. Protozool. 24, 518-522.
214. Young, R.W., 1968, Passage of newly formed protein through the connecting cilium of retinal rods in the frog. J. Ultrastruct. Res. 23, 462-473.
215. Young, R.W., 1970, Visual cells. Sci. Am. 223, 80-91
216. Young, R.W. and Droz, B., 1968, The renewal of protein in retinal rods and cones. J. Cell Biol. 39. 169-184.