Retinoic acid embryopathy: Case report and review of literature

Pediatric Pathology and Laboratory Medicine

Volumn 16, Issue 5, 1996, Pages 823-836

  Coberly, Suzanne ^a   Lammer, Edward ^a   Alashari, Mouied ^a  

^a CHILDREN S HOSPITAL OAKLAND   (United States)

Author keywords

Accutane; CNS anomalies; ear anomalies; embryopathy; isotretinoin; retinoic acid

Indexed keywords

ISOTRETINOIN; RETINOIC ACID DERIVATIVE;

ARTICLE; AUTOPSY; CARDIOVASCULAR MALFORMATION; CASE REPORT; CENTRAL NERVOUS SYSTEM MALFORMATION; EMBRYOPATHY; GROWTH RETARDATION; HUMAN; INFANT; LYMPHOCYTOPENIA; MALE; MICROTIA; PRIORITY JOURNAL; TELECANTHUS;

EMBRYONIC AND FETAL DEVELOPMENT; FATAL OUTCOME; HUMANS; ISOTRETINOIN; MALE;

EID: 0029742988     PISSN: 10771042     EISSN: None     Source Type: Journal    
DOI: 10.1080/107710496175435     Document Type: Article

References (24)

1. Larsen W. Human Embryology. New York: Churchill Livingstone, 1993.
2. Schardein JL. Chemically-Induced Birth Defects. 2nd ed. New York: Marcel Dekker, 1993.
3. Lammer EJ, Chen DT, Hoar RM, et al. Retinoic acid embryopathy. N Engl J Med 1985;313:837-41.
4. Lynburg MC, Khoury MJ, Lammer EJ, Waller KO, Cordero JF, Erickson JD. Sensitivity, specificity, and positive predictive value of multiple malformations in isotretinoin embryopathy surveillance. Teratology 1990;42:513-19.
5. Dai WS, LaBraico JM, Stern RS. Epidemiology of isotretinoin exposure during pregnancy. J Am Acad Dermatol 1992:26:599-606.
6. Fernhoff PM, Lammer EJ. Craniofacial features of isotretinoin embryopathy. J Pediatr 1984;05:595-97.
7. Rappaport EB, Knapp M. Isotretinoin embryopathy - a continuing problem. J Clin Pharmacol 1989;29:463-5.
8. Rosa FW, Wilk AL, Kelsey FO. Teratogen update: Vitamin A congeners. Teratology 1986;33:355-64.
9. Webster WS, Johnston MC, Lammer FJ, Sulik KK. Isotretinoin embryopathy and the cranial neural crest: An in vivo and in vitro study. J Craniofac Genet Dev Biol 1986;6:211-22.
10. Hummler H, Korte R, Hendrickx AG. Induction of malformations in cynomolgus monkey with 13-cis-retinoic acid. Teratology 1990;42:263-72.
11. Johnston MC, Bronsky PT. Animal models for human craniofacial malformations. J Craniofac Genet Dev Biol 1991;11:227-91.
12. Pratt RM, Goulding EH, Abbott BD. Retinoic acid inhibits migration of cranial neural crest cells in the cultured mouse embryo. J Craniofac Genet Dev Biol 1987;7:205-17.
13. Watanabe T, Goulding EH, Pratt RM. Alteration in craniofacial growth induced by isotretinoin (13-cis-retinoic acid) in mouse whole embryo and primary mesenchymal cell culture. J Craniofac Genet Dev Biol 1988;8:21-33.
14. Lammer EJ, Armstrong DL. Malformations of hindbrain structures among humans exposed to isotretinoin (13-cis-retinoic acid) during early embryogenesis. In: Morriss-Kay G, ed. Retinoids in Normal Development and Teratogenesis. New York: Oxford University Press, 1991;281-95.
15. Dencker L, Gustafson AL, Annerwall E, Busch C, Erickson U. Retinoid-binding proteins in craniofacial development. J Craniofac Genet Dev Biol 1991;11:303-14.
16. Kirby ML, Waldo MS. Role of neural crest in congenital heart disease. Circulation 1990;82:332-40.
17. Jarvis BL, Johnston MC, Sulik KK. Congenital malformations of the external, middle and inner ear produced by isotretinoin exposure in mouse embryos. Otolaryngol Head Neck Surg 1990;102:391-401.
18. Burk DT, Willhite CC. Inner ear malformations induced by isotretinoin in hamster fetuses. Teratology 1992;46:147-57.
19. Ohtani I, Schuknecht HF. Temporal bone pathology in DiGeorge's syndrome. Ann Otol Rhinol Laryngol 1984;93:220-4.
20. Guyot JP, Gacek RR, DiRaddo P. The temporal bone anomaly in CHARGE association. Arch Otolaryngol Head Neck Surg 1987;113:321-4.
21. Jones KL. Smith's Recognizable Patterns of Human Malformation. 4th ed. Philadelphia: W. B. Saunders, 1988.
22. Rizzo R, Lammer EJ, Parano E, Pavone L, Argyle C. Limb reduction defects in humans associated with prenatal isotretinoin exposure. Teratology 1991;44:599-604.
23. Lammer EJ. Embryopathy in infant conceived one year after termination of maternal etretinate. Lancet 1988;2:1080-1.
24. Blake KD, Wyse RKH. Embryopathy in infant conceived one year after termination of maternal etretinate: A reappraisal. Lancet 1988;2:1254.