Mercaptide formed between the residue Cys70 and Hg2+ or Co2+ behaves as a functional positively charged side chain operative in the Arg70 → Cys mutant of the metal-tetracycline/H+ antiporter of Escherichia coli

Biochemistry

Volumn 35, Issue 29, 1996, Pages 9385-9391

  Someya, Yuichi ^a   Yamaguchi, Akihito ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPORTER; ARGININE; CARRIER PROTEIN; COBALT; CYSTEINE; MERCURY; METAL; MUTANT PROTEIN; TETRACYCLINE; THIOL GROUP;

AMINO ACID SUBSTITUTION; ARTICLE; CHELATION; CONTROLLED STUDY; ESCHERICHIA COLI; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; SITE DIRECTED MUTAGENESIS;

ANTIPORTERS; ARGININE; BACTERIAL PROTEINS; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELL MEMBRANE; COBALT; CYSTEINE; DNA PRIMERS; ESCHERICHIA COLI; KINETICS; MAGNESIUM; MANGANESE; MERCURY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; POINT MUTATION; SULFHYDRYL REAGENTS; TETRACYCLINE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0029742849     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi961026z     Document Type: Article

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