T-cell receptor β variable region (Vβ) usage in cutaneous T-cell lymphomas (CTCL) in comparison to normal and eczematous skin

Journal of Cutaneous Pathology

Volumn 23, Issue 4, 1996, Pages 298-305

  Potoczna, Natascha ^a   Boehncke, Wolf Henning ^b   Nestle, Frank O ^a   Küenzlen, Christiane ^b   Sterry, Wolfram ^c   Burg, Günter ^a   Dummer, Reinhard ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF ULM   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

T LYMPHOCYTE RECEPTOR;

ARTICLE; CONTROLLED STUDY; DERMIS; DISEASE COURSE; ECZEMA; EPIDERMIS; HUMAN; HUMAN TISSUE; LYMPHOCYTE COUNT; LYMPHOMATOID PAPULOSIS; MAJOR CLINICAL STUDY; MONONUCLEAR CELL; MYCOSIS FUNGOIDES; PARAPSORIASIS; SEZARY SYNDROME; SKIN BIOPSY; SKIN LYMPHOMA; T CELL LYMPHOMA;

EID: 0029742677     PISSN: 03036987     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0560.1996.tb01301.x     Document Type: Article

References (31)

1. Burg G, Dummer R, Kerl H. Classification of cutaneous lymphomas. Derm Clinics 1994: 12: 213.
2. Sterry W, Mielke V. CD4+ cutaneous T-cell lymphomas show the phenotype of helper/inducer T cells (CD45RA-, CDw29+). J Invest Dermatol 1989: 93: 413.
3. Geib A, Smoller B, Warnke R, Picker L. Lymphocytes infiltrating primary cutaneous neoplasms selectively express the cutaneous lymphocyte-associated antigen (CLA). Am J Pathol 1993: 142: 1556.
4. Wood GS, Haeffner AC, Dummer R, Crooks C. Molecular biology techniques for the diagnosis of CTCL. Dermatol Clinics 1994: 12: 231.
5. Tokura Y, Heald PW, Yan SL, Edelson RL. Stimulation of cutaneous T-cell lymphoma cells with superantigenic staphylococcal toxins. J Invest Dermatol 1992: 98: 33.
6. Cordell JL, Falini B, Erber WN, et al. Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes). J Histochem Cytochem 1984: 32: 219.
7. Dummer R, Potoczna N, Haeffner AC, Gilardi F, Zimmermann D, Burg G. A primary cutaneous non-T non-B CD4+, CD56+ lymphoma. Arch Dermatol 1996:132: 550.
8. Weiss L, Hu E, Wood GS, et al. Clonal rearrangements of T-cell receptor genes in mycosis fungoides and dermatopathic lymphadenopathy. N Engl J Med 1985: 313: 539.
9. Wood GS, Tung RM, Haeffner AC, et al. Detection of clonal T-cell receptor gamma gene rearrangements in early mycosis fungoides/Sezary syndrome by polymerase chain reaction and denaturing gradient gel electrophoresis (PCR/DGGE). J Invest Dermatol 1994: 103: 34.
10. Staib G, Mielke V, Griesser H, Menke M, Duller B, Sterry W. PCR-analysis of T-cell receptor (TCR)-gamma genes to differentiate between malignant and reactive T-cell infiltrates of the skin. J Invest Dermatol 1993: 100: 458 (abstract).
11. Boehncke WH, Krettek S, Parwaresch MR, Sterry W. Demonstration of clonal disease in early mycosis fungoides. Am J Dermatopathol 1992: 14: 95.
12. O'Grady J, Krajewski AS, Ramage EF. Demonstration of clonality in T-cell lymphoma using an anti-T-cell receptor variable region antibody panel. Histopathology 1990: 17: 553.
13. Bahler DW, Berry G, Oksenberg J, Warnke RA, Levy R. Diversity of T-cell antigen receptor variable genes used by mycosis fungoides cells. Am J Pathol 1992: 140: 1.
14. Bagot M, Wechsler J, Lescs MC, Revuz J, Farcet JP, Gaulard P. Intraepidermal localization of the clone in cutaneous T-cell lymphoma. J Am Acad Dermatol 1992: 27: 589.
15. Ralfkiaer E, Wollf SA, Vejlsgaard GL. Use of antibodies against the variable regions of the T-cell receptor alpha/ beta heterodimer for the study of cutaneous T-cell lymphomas. Br J Dermatol 1991: 125: 409.
16. Jack AS, Boylston AW, Carrel S, Grigor I. Cutaneous T-cell lymphoma cells employ a restricted range of T-cell antigen receptor variable region genes. Am J Pathol 1990: 136: 17.
17. McHenry PM, Campbell I, Mackie RM. Assessment of an anti-T-cell receptor variable region antibody panel in cutaneous T-cell lymphoma. Br J Dermatol 1994: 130: 595.
18. Gilks CB, Ho VC, Gascoyne RD, Ellison DJ. T-cell receptor variable region gene expression in cutaneous T-cell lymphomas. J Cutan Pathol 1992: 19: 21.
19. Poppema S, Hepperle B. Restricted V gene usage in T-cell lymphomas as detected by anti-T-cell receptor variable region reagents. Am J Pathol 1991: 138: 1479.
20. Gorochov G, Bachelez H, Gayuela JM, et al. Expression of Vbeta segments by Sézary cells. J Invest Dermatol 1995: 105: 56.
21. Dunn DA, Gadenne AS, Simha S, Lerner EA, Bigby M, Bleicher PA. T-cell receptor V beta expression in normal human skin. Proc Natl Acad Sci USA 1993: 90: 1267.
22. Häffner A, Zepter K, Dummer R, Wood G. T-cell receptor usage in cutaneous malignancies. J Invest Dermatol 1994: 103: 742.
23. Boehncke WH, Dressel D, Manfras B, et al. T-cell-receptor repertoire in chronic plaque-stage psoriasis is restricted and lacks enrichement of superantigen-associated Vbeta regions. J Invest Dermatol 1995: 104: 725.
24. Herman A, Kappler JW, Marrack P, Pullen AM. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu Rev Immunol 1991: 9: 745.
25. Fleischer B, Gerardy Schahn R, Metzroth B, Carrel S, Gerlach D, Kohler W. An evolutionary conserved mechanism of T cell activation by microbial toxins. Evidence for different affinities of T cell receptor-toxin interaction. J Immunol 1991: 146: 11.
26. Fleischer B. Superantigens. Apmis 1994: 102: 3.
27. Quaratino S, Verhoef A, Kahan M, Londei M. Expression of the identical V beta gene in human T-rell clones does not confer the same pattern of responsiveness to bacterial enterotoxins. Immunology 1993: 78: 600.
28. Dummer R, Schwarz T. Cytokines as regulatory proteins in cutaneous lymphoproliferation. Dermatol Clin 1994: 12: 283.
29. Charley M, McCoy JP, Deng JS, Jegasothy B. Anti-V region antibodies as "almost clonotypic" reagents for the study of cutaneous T cell lymphomas and leukemias. J Invest Dermatol 1990: 95: 614.
30. Hunt SJ, Charley MR, Jegasothy BV. Cutaneous T-cell lymphoma: utility of antibodies to the variable regions of the human T-cell antigen receptor. J Am Acad Dermatol 1992: 26: 552.
31. Salter DM, Krajewski AS, Dewar AK. The use of anticlonotypic T-cell receptor antibodies in the diagnosis of T-cell lymphoma. J Pathol 1988: 155: 344A.