Axoglial dysjunction: A critical appraisal of definition, techniques, and previous results

Microscopy Research and Technique

Volumn 34, Issue 5, 1996, Pages 436-444

  Giannini, Caterina ^a   Dyck, Peter James ^a  

^a MAYO CLINIC   (United States)

Author keywords

Axoglial dysjunction; Axoglial transverse bands; Diabetic polyneuropathy; Nodes of Ranvier

Indexed keywords

AXOGLIAL DYSJUNCTION; AXOGLIAL TRANSVERSE BAND; DIABETIC POLYNEUROPATHY; NODE OF RANVIER; POLYNEUROPATHY;

ADULT; CELL ULTRASTRUCTURE; DIABETIC NEUROPATHY; ELECTRON MICROSCOPY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROSCOPIC ANATOMY; NEUROPATHOLOGY; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RANVIER NODE; REVIEW;

EID: 0029742349     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0029(19960801)34:5<436::AID-JEMT3>3.0.CO;2-K     Document Type: Review

References (17)

1. Sima, A.A.F., Lattimer, S.A., Hagihashi, S., and Greene, D.A. (1986) Axoglial dysjunction. A novel structural lesion that accounts for poorly-reversible nerve conduction slowing in the spontaneously-diabetic Bio-breeding rat. J. Clin. Invest., 77:474-485.
2. Sima, A.A.F., Nathaniel, V., Bril, V., McEwen, T.A.J., and Greene, D.A. (1988) Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axoglial dysjunction in human diabetic neuropathy. J. Clin. Invest., 81:349-364.
3. Laatsch, R.H., and Cowan, W.M. (1966) A structural specialization at nodes of Ranvier in the central nervous system. Nature, 210:757-758.
4. Rosenbluth, J. (1978) Glial membrane specializations in extra-paranodal regions. J. Neurocytol. 7:709-719.
5. Bertram, M., and Schröder, J.M. (1993) Developmental changes at the node and paranode in human sural nerves: Morphometric and fine-structural evaluation. Cell. Tissue Res., 273:499-509.
6. Harkin, J.C. (1964) A series of desmosomal attachments in the Schwann sheath of myelinated mammalian nerves. Z. Zellforsch. 64:189-195.
7. Phillips, D.D., Hibbs, R.G., Ellison, J.P., and Shapiro, H. (1972) An electron microscopic study of central and peripheral nodes of Ranvier. J. Anat., 111:229-238.
8. Thomas, P.K., Ochoa, J., Berthold, C.-H., Carlstedt T., and Corneliuson, O. (1993) Microscopic anatomy of the peripheral nervous system. In: Peripheral Neuropathy. 3rd ed. P.J. Dyck, P.K. Thomas, J.W. Griffin, P.A. Low, J.F. Poduslo, eds. W. B. Saunders, Philadelphia, pp. 41-44.
9. Berthold, C.H. (1968) Ultrastructure of postnatally developing feline peripheral nodes of Ranvier. Acta Soc. Med. Ups., 73:145-166.
10. Berthold, C.H., and Skoglund, S. (1968) Postnatal development of feline paranodal myelin-sheath segments. II. Electron microscopy. Acta Soc. Med. Ups., 73:127-144.
11. Berthold, C.H. (1967) Physiology and Pathobiology of Axons. In: Physiology and Pathobiology of Axons. S.G. Waxman, ed. Raven Press, New York, pp. 3-63.
12. Yu, R.C.P., and Bunge, R.P. (1975) Damage and repair of the peripheral myelin sheath and node of Ranvier after treatment with trypsin. J. Cell Biol. 64:1-14.
13. Hirano, A., Cook, S.D., Whitaker, J.N., Dowling, P.C., and Murray, M.R. (1971) Fine structural aspects of demyelination in vitro. The effects of Guillain-Barre' serum. J. Neuropathol. Exp. Neurol., 30:249-256.
14. Allt, G. (1975) The node of Ranvier in experimental allergic neuritis: An electron microscope study. J. Neurocytol., 4:63-76.
15. Allt, G. (1969) Repair of segmental demyelination in peripheral nerve. An electron microscopic study. Brain 92:639-646.
16. Scherer, S.S., Deschenes, S., Fischbeck, K., and Paul, D. (1994) Connexin32 is expressed by myelinating Schwann cells. Peripheral Nerve Society Mtg., 36 (Abstr.).
17. Sima, A.A.F., Brown, M.B., Prashar, A., Chakrabarti, S., Laudadio, C., and Greene, D.A. (1992) The reproducibility and sensitivity of sural nerve morphometry in the assessment of diabetic peripheral polyneuropathy. Diabetologia 35:560-569.