A Facile Synthesis of (R)-3-Amino-4-phenylbutyric Acid from L-Aspartic Acid

Bioscience, Biotechnology and Biochemistry

Volumn 60, Issue 5, 1996, Pages 916-917

  Seki, Masahiko ^a   Matsumoto, Kazuo ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

4 phenyl 3 aminobutyric acid; Friedel Crafts acylation; aminoketone; amino acid; L aspartic acid

Indexed keywords

EID: 0029742287     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.60.916     Document Type: Article

References (13)

1. D. C. Cole. Tetrahedron. 50, 9517-9582 (1994) and references cited therein.
2. N. C. Chaturvedi, W. K. Park, R. R. Smeby and K. M. Bumpus. J. Med. Chem. 13, 177-181 (1970);
3. K. Plucinka and B. Liberek. Tetrahedron. 43. 3509-3517 (1987);
4. M. Rodrigues, A. Aumelas, and J. Martinez, Tetrahedron Lett. 31. 5153-5156 (1990).
5. P. Gmeiner, Tetrahedron Lett. 31, 5717-5720 (1990);
6. K. S. Chu and J. P. Konopelski, Tetrahedron. 49, 9183-9190 (1990);
7. A. El Marino, M. L. Roumestant, R. Viallefont, D. Razafindramboa, M. Bonato, and M. Follet, Synthesis, 1192, 1104-1108;
8. C. W. Jetford and J. Wang, Tetrahedron Lett. 34, 1111-1114 (1993). Utilization of aspartic acid for drug synthesis.
9. K. Matsumoto and M. Seki. J. Svn. Org. Chem. Jpn. 49. 26-41 (1991)
10. M. Seki and K. Matsumoto. Bioindustrv. 12. 5-19 (1995).
11. I. Chibata, T. Tosa, and T. Sato, Appl. Bioehem. Biotech. 13, 231-240 (1986);
12. I. Chibata, T. Tosa, T. Sato, and K. Yamamoto, Japan Kokai Tokkyo Kouho. 100-289 (Aug. 8, 1975).
13. M. Seki, T. Moriya, and K. Matsumoto, Agrie. Biol. Chem. 51. 3033-3038 (1987)