Expression of the apoptosis-mediator Fas is enhanced by dysfunctional mitochondria

Journal of Biochemistry

Volumn 120, Issue 3, 1996, Pages 600-607

  Asoh, Sadamitsu ^a   Mori, Takashi ^a   Hayashi, Jun Ichi ^b   Ohta, Shigeo ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

Apoptosis; Fas antigen; Gene expression; Mitochondria disease; Respiratory inhibitor

Indexed keywords

ANTIBODY; ANTIMYCIN A1; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; FAS ANTIGEN; MESSENGER RNA; MITOCHONDRIAL DNA; ROTENONE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DNA DETERMINATION; GENE; GENE DELETION; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; POINT MUTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0029741770     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021455     Document Type: Article

References (53)

1. DiMauro, S., Bonilla, E., Zeviani, M., Nakagawa, M., and DeVivo, D.C. (1985) Mitochondrial myopathies. Ann. Neurol. 17, 521-538
2. Kobayashi, Y., Momoi, M.Y., Tominaga, K., Momoi, T., Nihei, K., Yanagisawa, M., Kagawa, Y., and Ohta, S. (1990) A point mutation in the mitochondrial tRNA(Leu)(UUR) gene in MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes). Biochem. Biophys. Res. Commun. 173, 816-822
3. Kobayashi, Y., Momoi, M.Y., Tominaga, K., Shimoizumi, H., Nihei, K., Yanagisawa, M., Kagawa, Y., and Ohta, S. (1991) Respiration-deficient cells are caused by a single point mutation in the mitochondrial tRNA-Leu(UUR) gene in mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes (MELAS). Am. J. Hum. Genet. 49, 590-599
4. Wallace, D.C. (1992) Diseases of the mitochondrial DNA. Annu. Rev. Biochem. 61, 1175-1212
5. Taniike, M., Fukushima, H., Yanagihara, I., Tsukamoto, H., Tanaka, J., Fujimura, H., Nagai, T., Sano, T., Yamaoka, K., Inui, K., and Okada, S. (1992) Mitochondrial tRNA(Ile) mutation in fatal cardiomyopathy. Biochem. Biophys. Res. Commun. 186, 47-53
6. Hayashi, J.-I., Ohta, S., Kagawa, Y., Takai, D., Miyabayashi, S., Tada, K., Fukushima, H., Inui, K., Okada, S., Goto, Y.-i., and Nonaka, I. (1994) Functional and morphological abnormalities of mitochondria in human cells containing mitochondrial DNA with pathogenic point mutations in tRNA genes. J. Biol. Chem. 269, 19060-19066
7. Hayashi, J.-I., Ohta, S., Kikuchi, A., Takemitsu, M., Goto, Y.-i., and Nonaka, I. (1991) Introduction of disease-related mitochondrial DNA deletions into HeLa cells lacking mitochondrial DNA results in mitochondrial dysfunction. Proc. Natl. Acad. Sci. USA 88, 10614-10618
8. Chomyn, A., Meola, G., Bresolin, N., Lai, S.T., Scarlato, G., and Attardi, G. (1991) In vitro genetic transfer of protein synthesis and respiration defects to mitochondrial DNA-less cells with myopathy-patient mitochondria. Mol. Cell. Biol. 11, 2236-2244
9. King, M.P., Koga, Y., Davidson, M., and Schon, E.A. (1992) Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. Mol. Cell. Biol. 12, 480-490
10. Chomyn, A., Martinuzzi, A., Yoneda, M., Daga, A., Hurko, O., Johns, D., Lai, S.T., Nonaka, I., Angelini, C., and Attardi, G. (1992) MELAS mutation in mtDNA binding site for transcription termination factor causes defects in protein synthesis and in respiration but no change in levels of upstream and downstream mature transcripts. Proc. Natl. Acad. Sci. USA 89, 4221-4225
11. Majno, G. and Joris, I. (1995) Apoptosis, oncosis, and necrosis. An overview of cell death. Am. J. Pathol. 146, 3-15
12. Wyllie, A.H., Kerr, J.F., and Currie, A.R. (1980) Cell death: The significance of apoptosis. Int. Rev. Cytol. 68, 251-306
13. Wyllie, A.M. and Morris, R.G. (1982) Hormone-induced cell death. Purification and properties of thymocytes undergoing apoptosis after glucocorticoid treatment. Am. J. Pathol. 109, 78-87
14. Arends, M.J., Morris, R.G., and Wyllie, A.H. (1990) Apoptosis. The role of the endonuclease. Am. J. Pathol. 136, 593-608
15. Roy, C., Brown, D.L., Little, J.E., Valentine, B.K., Walker, P.E., Sikorska, M., Leblanc, J., and Chaly, N. (1992) The topoisomerase II inhibitor teniposide (VM-26) induces apoptosis in unstimulated mature murine lymphocytes. Exp. Cell. Res. 200, 416-424
16. Oberhammer, F., Wilson, J.W., Dive, C., Morris, I.D., Hickman, J.A., Wakeling, A.E., Walker, P.R., and Sikorska, M. (1993) Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12, 3679-3684
17. Brown, D.G., Sun, X.-M., and Cohen, G.M. (1993) Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J. Biol. Chem. 268, 3037-3039
18. Yonehara, S., Ishii, A., and Yonehara, M. (1989) A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen codownregulated with the receptor of tumor necrosis factor. J. Exp. Med. 169, 1747-1756
19. Itoh, N., Yonehara, S., Ishii, A., Yonehara, M., Mizushima, S.-I., Sameshima, M., Hase, A., Seto, Y., and Nagata, S. (1991) The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66, 233-243
20. Suda, T., Takahashi, T., Golstein, P., and Nagata, S. (1993) Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family. Cell 75, 1169-1178
21. Oehm, A., Behrmann, I., Falk, W., Pawlita, M., Maier, G., Klas, C., Li-Weber, M., Richards, S., Dhein, J., Trauth, B.C., Ponsting, H., and Krammer, P.H. (1992) Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. J. Biol. Chem. 267, 10709-10715
22. Watanabe-Fukunaga, R., Brannan, C.I., Itoh, N., Yonehara, S., Copeland, N.G., Jenkins, N.A., and Nagata, S. (1992) The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J. Immunol. 148, 1274-1279
23. Krammer, P.H., Dhein, J., Walczak, H., Behrmann, I., Mariani, S., Matiba, B., Path, M., Daniel, P.T., Knipping, E., Westendorp, M.O., Stricker, K., Baumler, C., Hellbardt, S., Germer, M., Peter, M.E., and Debatin, K.-M. (1994) The role of APO-1-mediated apoptosis in the immune system. Immunol. Rev. 142, 175-191
24. Hayashi, J.-I., Yonekawa, H., Watanabe, S., Nonaka, I., Momoi, M.Y., Kagawa, Y., and Ohta, S. (1991) Somatic cell genetical approaches to mitochondrial diseases in Progress in Neuropathology (Sato, T. and DiMauro, S., eds.) Vol. 7, pp. 93-102, Raven Press, New York
25. Hayashi, J.-I., Ohta, S., Kagawa, Y., Kondo, H., Kaneda, H., Yonekawa, H., Takai, D., and Miyabayashi, S. (1994) Nuclear but not mitochondrial genome involvement in human age-related mitochondrial dysfunction. Functional integrity of mitochondrial DNA from aged subjects. J. Biol. Chem. 269, 6878-6883
26. Noonan, K.E., Beck, C., Holzmayer, T.A., Chin, J.E., Wunder, J.S., Andrulis, I.L., Gazdar, A.F., Willman, C.L., Griffith, B., Von Hoff, D.D., and Roninson, I.B. (1990) Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction. Proc. Natl. Acad. Sci. USA 87, 7160-7164
27. Kinoshita, T., Imamura, J., Nagai, H., and Shimotohno, K. (1992) Quantification of gene expression over a wide range by the polymerase chain reaction. Anal. Biochem. 206, 231-235
28. Bosma, P.J. and Kooistra, T. (1991) Different induction of two plasminogen activator inhibitor 1 mRNA species by phorbol ester in human hepatoma cells. J. Biol. Chem. 266, 17845-17849
29. Zentella, A., Weis, F.M.B., Ralph, D.A., Laiho, M., and Massagué, J. (1991) Early gene responses to transforming growth factor-β in cells lacking growth-suppressive RB function. Mol. Cell. Biol. 11, 4952-4958
30. Yoneda, M., Chomyn, A., Martinuzzi, A., Hurko, O., and Attardi, G. (1992) Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proc. Natl. Acad. Sci. USA 89, 11164-11168
31. Kobayashi, Y., Ichihashi, K., Ohta, S., Nihei, K., Kagawa, Y., Yanagisawa, M., and Momoi, M.Y. (1992) The mutant mitochondrial genes in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) were selectively amplified through generations. J. Inherit. Metab. Dis. 15, 803-808
32. Gamen, S., Anel, A., Montoya, J., Marzo, I., Pineiro, A., and Naval, J. (1995) mtDNA-depleted U937 cells are sensitive to TNF and Fas-mediated cytotoxicity. FEBS Lett. 376, 15-18
33. Uenaka, R., Kuwajima, M., Ono, A., Matsuzawa, Y., Hayakawa, J.-I., Inohara, N., Kagawa, Y., and Ohta, S. (1996) Increased expression of carnitine palmitoyltransferase I gene is repressed by administering L-camitine-deficient juvenile visceral steatosis mice. J. Biochem. 119, 533-540
34. Hayashi, J.-I., Tanaka, M., Sato, W., Ozawa, T., Yonekawa, H., Kagawa, Y., and Ohta, S. (1990) Effects of ethidium bromide treatment of mouse cells on expression and assembly of nuclear-coded subunits of complexes involved in the oxidative phosphorylation. Biochem. Biophys. Res. Commun. 167, 216-221
35. Tominaga, K., Hayashi, J.-I., Kagawa, Y., and Ohta, S. (1993) Smaller isoform of human mitochondrial transcription factor 1 : Its wide distribution and production by alternative splicing. Biochem. Biophys. Res. Commun. 194, 544-551
36. Behrmann, I., Walczak, H., and Krammer, P.H. (1994) Structure of the human APO-1 gene. Eur. J. Immunol. 24, 3057-3062
37. Cheng, J., Liu, C., Koopman, W.J., and Mountz, J.D. (1995) Characterization of human Fas gene. Exon/intron organization and promoter region. J. Immunol. 154, 1239-1245
38. Takizawa, T., Fukuda, R., Miyawaki, T., Ohashi, K., and Nakanishi, Y. (1995) Activation of the apoptotic Fas antigen-encoding gene upon influenza virus infection involving spontaneously produced beta-interferon. Virology 209, 288-296
39. Cascino, I., Fiucci, G., Papoff, G., and Ruberti, G. (1995) Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. J. Immunol. 154, 2706-2713
40. Matsuyama, T., Hata, R., Tagaya, M., Yamamoto, Y., Nakajima, T., Furuyama, J.-i., Wanaka, A., and Sugita, M. (1994) Fas antigen mRNA induction in postischemic murine brain. Brain Res. 657, 342-346
41. Ito, M., Watanabe, M., Ihara, T., Kamiya, H., and Sakurai, M. (1995) Fas antigen and bcl-2 expression on lymphocytes cultured with cytomegalovirus and varicella-zoster virus antigen. Cell. Immunol. 160, 173-177
42. Takizawa, T., Matsukawa, S., Higuchi, Y., Nakamura, S., Nakanishi, Y., and Fukuda, R. (1993) Induction of programmed cell death (apoptosis) by influenza virus infection in tissue culture cells. J. Gen. Virol. 74, 2347-2355
43. Yoshida, H., Sumichika, H., Hamano, S., He, X., Minamishima, Y., Kimura, G., and Nomoto, K. (1995) Induction of apoptosis of T cells by infecting mice with murine cytomegalovirus. J. Virol. 69, 4769-4775
44. Katsikis, P.D., Wunderlich, E.S., Smith, C.A., Herzenberg, L.A., and Herzenberg, L.A. (1995) Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals. J. Exp. Med. 181, 2029-2036
45. Maciejewski, J., Selleri, C., Anderson, S., and Young, N.S. (1995) Fas antigen expression on CD34 + human marrow cells is induced by Interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro. Blood 85, 3183-3190
46. Panayiotidis, P., Ganeshaguru, K., Foroni, L., and Hoffbrand, A.V. (1995) Expression and function of the FAS antigen in B chronic lymphocytic leukemia and hairy cell leukemia. Leukemia 9, 1227-1232
47. Quirk, S.M., Cowan, R.G., Joshi, S.G., and Henrikson, K.P. (1995) Fas antigen-mediated apoptosis in human granulosa/luteal cells. Biol. Reprod. 52, 279-287
48. Nagafuji, K., Shibuya, T., Harada, M., Mizuno, S.-i., Takenaka, K., Miyamoto, T., Okamura, T., Gondo, H., and Niho, Y. (1995) Functional expression of Fas antigen (CD95) on hematopoietic progenitor cells. Blood 86, 883-889
49. Tartaglia, L.A., Ayres, T.M., Wong, G.H.W., and Goeddel, D.V. (1993) A novel domain within the 55 kd TNF receptor signals cell death. Cell 74, 845-853
50. Wada, N., Matsumura, M., Ohba, Y., Kobayashi, N., Takizawa, T., and Nakanishi, Y. (1995) Transcription stimulation of the Fas-encoding gene by nuclear factor for interleukin-6 expression upon influenza virus infection. J. Biol. Chem. 270, 18007-18012
51. Owen-Schaub, L.B., Zhang, W., Cusack, J.C., Angelo, L.S., Santee, S.M., Fujiwara, T., Roth, J.A., Deisseroth, A.B., Zhang, W.-W., Kruzel, E., and Radinsky, R. (1995) Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression. Mol. Cell. Biol. 15, 3032-3040
52. Schulze-Osthoff, K., Bakker, A.C., Vanhaesebroeck, B., Beyaert, R., Jacob, W.A., and Fiers, W. (1992) Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions. J. Biol. Chem. 267, 5317-5323
53. Wolvetang, E.J., Johnson, K.L., Krauer, K., Ralph, S.J., and Linnane, A.W. (1994) Mitochondrial respiratory chain inhibitors induce apoptosis. FEBS Lett. 339, 40-44