메뉴 건너뛰기




Volumn 16, Issue 3, 1996, Pages 166-173

Strain- and sex-specific variations in hepatic glutamine synthetase activity and distribution in rats and mice

Author keywords

6 phosphate dehydrogenase; Dexamethasone; Estrogen; Glucose; Glutamine synthetase; Growth hormone; Immunohistochemistry; Lobular heterogeneity; Primary culture; Rat and mouse liver; Sex difference; Testosterone

Indexed keywords

DEXAMETHASONE; ESTROGEN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTAMATE AMMONIA LIGASE; GROWTH HORMONE; SEX HORMONE; TESTOSTERONE;

EID: 0029741715     PISSN: 01069543     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0676.1996.tb00723.x     Document Type: Article
Times cited : (21)

References (37)
  • 1
    • 0026766117 scopus 로고
    • Metabolic zonation of the liver: Regulation and implications for liver function
    • GEBHARDT R. Metabolic zonation of the liver: regulation and implications for liver function. Pharmacol Ther 1992: 53: 275-354.
    • (1992) Pharmacol Ther , vol.53 , pp. 275-354
    • Gebhardt, R.1
  • 2
    • 0024336445 scopus 로고
    • Functional specialization of different hepatocyte populations
    • JUNGERMANN K, KATZ N. Functional specialization of different hepatocyte populations. Physiol Rev 1989: 69: 708-751.
    • (1989) Physiol Rev , vol.69 , pp. 708-751
    • Jungermann, K.1    Katz, N.2
  • 3
    • 0002339868 scopus 로고
    • Cellular distribution and regulation of glutamine synthetase in liver
    • Häussinger D, Sies H, eds. Heidelberg: Springer-Verlag
    • GEBHARDT R, MECKE D. Cellular distribution and regulation of glutamine synthetase in liver. In: Häussinger D, Sies H, eds. Glutamate metabolism in mammalian tissues. Heidelberg: Springer-Verlag, 1984: 98-121.
    • (1984) Glutamate Metabolism in Mammalian Tissues , pp. 98-121
    • Gebhardt, R.1    Mecke, D.2
  • 4
    • 9444246701 scopus 로고
    • Development of hepatocyte heterogeneity
    • Gumucio JJ, ed. Berlin: Springer International
    • MOORMAN AFM, CHARLES R, LAMERS WH. Development of hepatocyte heterogeneity. In: Gumucio JJ, ed. Revisiones sobre biologica cellular. Berlin: Springer International, 1989: 19: 28-42.
    • (1989) Revisiones Sobre Biologica Cellular , vol.19 , pp. 28-42
    • Moorman, A.F.M.1    Charles, R.2    Lamers, W.H.3
  • 5
    • 0024506258 scopus 로고
    • Zonal distribution of fatty acid synthase in liver parenchyma of male and female rats
    • KATZ N, THIELE J, GIFFHORN-KATZ S. Zonal distribution of fatty acid synthase in liver parenchyma of male and female rats. Eur J Biochem 1989: 180: 185-189.
    • (1989) Eur J Biochem , vol.180 , pp. 185-189
    • Katz, N.1    Thiele, J.2    Giffhorn-Katz, S.3
  • 6
    • 0020421033 scopus 로고
    • Postnatal differentiation of sex-specific distribution patterns of G6Pase, G6PDH and ME in the rat
    • SASSE D, HOFFMAN H. Postnatal differentiation of sex-specific distribution patterns of G6Pase, G6PDH and ME in the rat. Histochemistry 1982: 75: 31-42.
    • (1982) Histochemistry , vol.75 , pp. 31-42
    • Sasse, D.1    Hoffman, H.2
  • 7
    • 0021277265 scopus 로고
    • Sex-specific regionality of liver metabolism during starvation with special reference to the heterogeneity of the lobular periphery
    • TEUTSCH HF. Sex-specific regionality of liver metabolism during starvation with special reference to the heterogeneity of the lobular periphery. Histochemistry 1984: 81: 87-92.
    • (1984) Histochemistry , vol.81 , pp. 87-92
    • Teutsch, H.F.1
  • 8
    • 0023243882 scopus 로고
    • Sex differences in the control of glucose-6-phosphate dehydrogenase and 6-phosphoglyconate dehydrogenase. Interaction of estrogen, testosteron and insulin in the regulation of enzyme levels in vivo and in cultured hepatocytes
    • HANSEN RJ, JUNGERMANN K. Sex differences in the control of glucose-6-phosphate dehydrogenase and 6-phosphoglyconate dehydrogenase. Interaction of estrogen, testosteron and insulin in the regulation of enzyme levels in vivo and in cultured hepatocytes. Biol Chem Hoppe-Seyler 1987: 368: 955-962.
    • (1987) Biol Chem Hoppe-Seyler , vol.368 , pp. 955-962
    • Hansen, R.J.1    Jungermann, K.2
  • 9
    • 0023837746 scopus 로고
    • Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression
    • WAXMAN DJ. Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression. Biochem Pharmacol 1988: 37: 71-84.
    • (1988) Biochem Pharmacol , vol.37 , pp. 71-84
    • Waxman, D.J.1
  • 10
    • 0020699358 scopus 로고
    • Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture
    • GEBHARDT R, MECKE D. Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture. EMBO J 1983: 2: 567-570.
    • (1983) EMBO J , vol.2 , pp. 567-570
    • Gebhardt, R.1    Mecke, D.2
  • 11
    • 0026320434 scopus 로고
    • Hepatocellular heterogeneity in ammonia-metabolism: Demonstration of limited colocalization of carbamoyl-phosphate synthetase and glutamine synthetase
    • GEBHARDT R, LINDROS K, LAMERS WH, MOORMAN AFM. Hepatocellular heterogeneity in ammonia-metabolism: demonstration of limited colocalization of carbamoyl-phosphate synthetase and glutamine synthetase. Eur J Cell Biol 1991: 56: 464-467.
    • (1991) Eur J Cell Biol , vol.56 , pp. 464-467
    • Gebhardt, R.1    Lindros, K.2    Lamers, W.H.3    Moorman, A.F.M.4
  • 12
    • 0024521281 scopus 로고
    • Immunohistochemical localization of glutamine synthetase in human liver
    • GEBHARDT R, SCHMID H, FITZKE H. Immunohistochemical localization of glutamine synthetase in human liver. Experientia 1989: 45: 137-139.
    • (1989) Experientia , vol.45 , pp. 137-139
    • Gebhardt, R.1    Schmid, H.2    Fitzke, H.3
  • 13
    • 0023549638 scopus 로고
    • Acquisition of antigens characteristic of adult pericentral hepatocytes by differentiating fetal hepatocytes in vitro
    • BENNETT AL, PAULSON KE, MILLER RE, DARNELL Jr JE. Acquisition of antigens characteristic of adult pericentral hepatocytes by differentiating fetal hepatocytes in vitro. J Cell Biol 1987: 105: 1073-1085
    • (1987) J Cell Biol , vol.105 , pp. 1073-1085
    • Bennett, A.L.1    Paulson, K.E.2    Miller, R.E.3    Darnell Jr., J.E.4
  • 14
    • 0023865471 scopus 로고
    • Distribution of glutamine synthetase and carbamoylphosphate synthetase I in vertebrate liver
    • SMITH Jr DD, CAMPBELL JW. Distribution of glutamine synthetase and carbamoylphosphate synthetase I in vertebrate liver. Proc Natl Acad Sci USA 1988: 85: 160-164.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 160-164
    • Smith Jr., D.D.1    Campbell, J.W.2
  • 15
    • 0024535224 scopus 로고
    • Localization of ammonia-metabolizing enzymes in human liver: Ontogenesis of heterogeneity
    • MOORMAN AFM, VERMEULEN JLM, CHARLES R, LAMERS WH. Localization of ammonia-metabolizing enzymes in human liver: ontogenesis of heterogeneity. Hepatology 1988: 9: 367-372.
    • (1988) Hepatology , vol.9 , pp. 367-372
    • Moorman, A.F.M.1    Vermeulen, J.L.M.2    Charles, R.3    Lamers, W.H.4
  • 16
    • 0027451999 scopus 로고
    • Inhibition by gonadectomy of effects of 2-acetylaminofluorene in male, but not female rat liver
    • TOKUMO K, UMEMURA T, SIRMA H, GEBHARDT R, POIRIER M, WILLIAMS GM. Inhibition by gonadectomy of effects of 2-acetylaminofluorene in male, but not female rat liver. Carcinogenesis 1993: 14: 1747-1750.
    • (1993) Carcinogenesis , vol.14 , pp. 1747-1750
    • Tokumo, K.1    Umemura, T.2    Sirma, H.3    Gebhardt, R.4    Poirier, M.5    Williams, G.M.6
  • 17
    • 0026337224 scopus 로고
    • Glutamate uptake in primary cultures of biliary epithelial cells from normal rat liver
    • EISENMANN-TAPPE I, WIZIGMANN S, GEBHARDT R. Glutamate uptake in primary cultures of biliary epithelial cells from normal rat liver. Cell Biol Toxicol 1991: 7: 315-325.
    • (1991) Cell Biol Toxicol , vol.7 , pp. 315-325
    • Eisenmann-Tappe, I.1    Wizigmann, S.2    Gebhardt, R.3
  • 18
    • 0020332993 scopus 로고
    • Biliary secretion of sodium fluorescein in primary cultures of adult rat hepatocytes and its stimulation by nicotinamide
    • GEBHARDT R, JUNG W. Biliary secretion of sodium fluorescein in primary cultures of adult rat hepatocytes and its stimulation by nicotinamide. J Cell Sci 1982: 56: 233-244.
    • (1982) J Cell Sci , vol.56 , pp. 233-244
    • Gebhardt, R.1    Jung, W.2
  • 19
    • 0014787893 scopus 로고
    • The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes
    • STERNBERGER LA, HARDY Jr PH, CUCULIS JJ, MEYER HG. The unlabeled antibody enzyme method of immunohistochemistry. Preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes. J Histochem Cytochem 1970: 18: 315-333.
    • (1970) J Histochem Cytochem , vol.18 , pp. 315-333
    • Sternberger, L.A.1    Hardy Jr., P.H.2    Cuculis, J.J.3    Meyer, H.G.4
  • 20
    • 0024531649 scopus 로고
    • Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/collagenase perfusion
    • BURGER HJ, GEBHARDT R, MAYER C, MECKE D. Different capacities for amino acid transport in periportal and perivenous hepatocytes isolated by digitonin/collagenase perfusion. Hepatology 1989: 9: 22-28.
    • (1989) Hepatology , vol.9 , pp. 22-28
    • Burger, H.J.1    Gebhardt, R.2    Mayer, C.3    Mecke, D.4
  • 21
    • 0023730192 scopus 로고
    • Alterations of hepatic enzyme levels and of the acinar distribution of glutamine synthetase in response to experimental liver injury in the rat
    • GEBHARDT R, BURGER HJ, HEINI H, SCHREIBER KL, MECKE D. Alterations of hepatic enzyme levels and of the acinar distribution of glutamine synthetase in response to experimental liver injury in the rat. Hepatology 1988: 8: 822-830.
    • (1988) Hepatology , vol.8 , pp. 822-830
    • Gebhardt, R.1    Burger, H.J.2    Heini, H.3    Schreiber, K.L.4    Mecke, D.5
  • 22
    • 0018619895 scopus 로고
    • The role of growth hormone, dexamethason and trijodothyronine in the regulation of glutamine synthetase in primary cultures of rat hepatocytes
    • GEBHARDT R, MECKE D. The role of growth hormone, dexamethason and trijodothyronine in the regulation of glutamine synthetase in primary cultures of rat hepatocytes. Eur J Biochem 1979: 100: 519-525.
    • (1979) Eur J Biochem , vol.100 , pp. 519-525
    • Gebhardt, R.1    Mecke, D.2
  • 23
    • 0023013868 scopus 로고
    • Amino acid transport in adult rat epithelial cells
    • GEBHARDT R, WILLIAMS GM. Amino acid transport in adult rat epithelial cells. Cell Biol Toxicol 1986: 2: 9-20.
    • (1986) Cell Biol Toxicol , vol.2 , pp. 9-20
    • Gebhardt, R.1    Williams, G.M.2
  • 25
    • 0024350059 scopus 로고
    • Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations
    • GEBHARDT R, TANAKA T, WILLIAMS GM. Glutamine synthetase heterogeneous expression as a marker for the cellular lineage of preneoplastic and neoplastic liver populations. Carcinogenesis 1989: 10: 1917-1923.
    • (1989) Carcinogenesis , vol.10 , pp. 1917-1923
    • Gebhardt, R.1    Tanaka, T.2    Williams, G.M.3
  • 26
    • 0027442441 scopus 로고
    • Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression
    • WAGENAAR GT, CHAMULEAU RA, DE HAAN JG, et al. Experimental evidence that the physiological position of the liver within the circulation is not a major determinant of zonation of gene expression. Hepatology 1993: 18: 1144-1153.
    • (1993) Hepatology , vol.18 , pp. 1144-1153
    • Wagenaar, G.T.1    Chamuleau, R.A.2    De Haan, J.G.3
  • 27
    • 0025131373 scopus 로고
    • Induction of glutamine synthetase in periportal hepatocytes by co-cultivation with a liver epithelial cell line
    • SCHRODE W, MECKE D, GEBHARDT R. Induction of glutamine synthetase in periportal hepatocytes by co-cultivation with a liver epithelial cell line. Eur J Cell Biol 1990: 53: 35-41.
    • (1990) Eur J Cell Biol , vol.53 , pp. 35-41
    • Schrode, W.1    Mecke, D.2    Gebhardt, R.3
  • 28
    • 0028320587 scopus 로고
    • Heterogeneous (positional) expression of glutamine synthetase: Features, regulation and implications for hepatocarcinogenesis
    • GEBHARDT R, GAUNITZ F, MECKE D. Heterogeneous (positional) expression of glutamine synthetase: features, regulation and implications for hepatocarcinogenesis. Advan Enz Regul 1994: 34: 27-56.
    • (1994) Advan Enz Regul , vol.34 , pp. 27-56
    • Gebhardt, R.1    Gaunitz, F.2    Mecke, D.3
  • 29
    • 0025270827 scopus 로고
    • Growth hormone regulation of hepatic glutamine synthetase mRNA levels in rats
    • NOLAN EM, MASTERS JN, DUNN A. Growth hormone regulation of hepatic glutamine synthetase mRNA levels in rats. Mol Cell Endocrinol 1990: 69: 101-110.
    • (1990) Mol Cell Endocrinol , vol.69 , pp. 101-110
    • Nolan, E.M.1    Masters, J.N.2    Dunn, A.3
  • 30
    • 0027336722 scopus 로고
    • Identification and functional characterization of regulatory elements of the glutamine synthetase gene from rat liver
    • FAHRNER J, LABRUYERE WT, GAUNITZ C, MOORMAN AFM, GEBHARDT R, LAMERS WH. Identification and functional characterization of regulatory elements of the glutamine synthetase gene from rat liver. Eur J Biochem 1993: 213: 1067-1073.
    • (1993) Eur J Biochem , vol.213 , pp. 1067-1073
    • Fahrner, J.1    Labruyere, W.T.2    Gaunitz, C.3    Moorman, A.F.M.4    Gebhardt, R.5    Lamers, W.H.6
  • 31
    • 0022036752 scopus 로고
    • Sexual dimorphism in the control of growth hormone secretion
    • JANSSON J-O, EDEN S, ISAKSSON O. Sexual dimorphism in the control of growth hormone secretion. Endocrine Rev 1985: 6: 128-150.
    • (1985) Endocrine Rev , vol.6 , pp. 128-150
    • Jansson, J.-O.1    Eden, S.2    Isaksson, O.3
  • 32
    • 0020677188 scopus 로고
    • Hormone induced morphogenesis and growth: Role of mesenchymal-epithelial interactions
    • CUNHA GR, CHUNG LWK, SHANNON JM, TAGUCHI O, FUJII H. Hormone induced morphogenesis and growth: role of mesenchymal-epithelial interactions. Rec Prog Horm Res 1983: 39: 559-598.
    • (1983) Rec Prog Horm Res , vol.39 , pp. 559-598
    • Cunha, G.R.1    Chung, L.W.K.2    Shannon, J.M.3    Taguchi, O.4    Fujii, H.5
  • 33
    • 0025933048 scopus 로고
    • Evidence that interaction with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithin aminotransferase genes in the mouse liver
    • KUO FC, DARNELL Jr DD. Evidence that interaction with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithin aminotransferase genes in the mouse liver. Mol Cell Biol 1991: 11: 6050-6058.
    • (1991) Mol Cell Biol , vol.11 , pp. 6050-6058
    • Kuo, F.C.1    Darnell Jr., D.D.2
  • 35
    • 0018914373 scopus 로고
    • Possible growth hormone control of liver glutamine synthetase activity in rats
    • WONG BS, CHENOWETH ME, DUNN A. Possible growth hormone control of liver glutamine synthetase activity in rats. Endocrinol 1980: 106: 268-274.
    • (1980) Endocrinol , vol.106 , pp. 268-274
    • Wong, B.S.1    Chenoweth, M.E.2    Dunn, A.3
  • 36
    • 0024817153 scopus 로고
    • Hypophysectomy decreases and growth hormone increases the turnover and mass of rat liver glutamine synthetase
    • LIN C-K, DUNN A. Hypophysectomy decreases and growth hormone increases the turnover and mass of rat liver glutamine synthetase. Life Sci 1989: 45: 2443-2450.
    • (1989) Life Sci , vol.45 , pp. 2443-2450
    • Lin, C.-K.1    Dunn, A.2
  • 37
    • 0027349191 scopus 로고
    • Sexually differentiated expression of genes encoding the P5402C cytochromes in rat liver - A model system for studying the action of growth hormone
    • MODE A. Sexually differentiated expression of genes encoding the P5402C cytochromes in rat liver - a model system for studying the action of growth hormone. J Reprod Fertil Suppl 1993: 46: 77-86.
    • (1993) J Reprod Fertil Suppl , vol.46 , pp. 77-86
    • Mode, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.