BMP 7 is required for nephrogenesis, eye development, and skeletal patterning

Annals of the New York Academy of Sciences

Volumn 785, Issue , 1996, Pages 98-107

  Karsenty, Gerard ^a   Luo, Guangbin ^a   Hofmann, Clementine ^b,c   Bradley, Allan ^b  

^a UNIVERSITY OF TEXAS   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; BONE DEVELOPMENT; CONFERENCE PAPER; EYE DEVELOPMENT; GENE MUTATION; GLOMERULUS; KIDNEY DEVELOPMENT; LENS; MORPHOLOGY; MOUSE; NONHUMAN; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FAMILY;

EID: 0029741484     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb56247.x     Document Type: Conference Paper

References (21)

1. ARMSTRONGE, J. F., K. PRITCHARD-JONES, W. A. BICKMORE, N. D. HASTIE & J. B. L. BARD. 1992. The expression of the Wilms' tumor gene, WT-1, in the developing mammalian embryo. Mech. Dev. 40: 85-97.
2. DRESSLER, G. R., U. DEUTSCH, K. CHOWDHURY, H. O. NORNES & P. GRUSS. 1990. Pax 2, A new murine paired-box-containing gene and its expression in the developing excretory system. Development 109: 787-795.
3. FERGUSON, E. L. & K. V. ANDERSON. 1992. Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71: 451-461.
4. GRINDLEY, J. C., D. R. DAVIDSON & R. E. HILL. 1995. The role of Pax-6 in eye and nasal development. Development 121: 1433-1442.
5. GROBSTEIN, C. 1957. Some transmission characteristics of the tubule-inducing influence on mouse metanephrogenic mesenchyme. Exp. Cell Res. 13: 575-587.
6. GRUENWALD, P. 1937. Zur Entwicklungsmechanik der Urogenital-systems beim Huhn. Roux' Arch. 136: 786-813.
7. HALDER, G., P. CALLAERTS & W. J. GEHRING. 1995. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science 267: 1788-1792.
8. HOGAN, B. L. M., M. BLESSING, G. E. WINNIER, N. SUZUKI & C. M. JONES. 1995. Growth factor in development: The role of TGF-β related polypeptide signaling molecules in embryogenesis. Development 1994 Suppl.: 53-60.
9. KINGSLEY, D. M., A. E. BLAND, J. M. GRUBBER, P. C. MARKER, L. B. RUSSELL, N. G. COPELAND & N. A. JENKINS. 1992. The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGF-β superfamily. Cell 71: 399-410.
10. KLEIN, G., M. EKBLOM, L. FECKER, R. TIMPL & P. EKBLOM. 1990. Differential expression of laminin A and B chains during development of embryonic mouse organs. Development 110: 823-837.
11. LETTERIO, J. J., A. G. GEISER, A. B. KULKARNI, N. S. ROCHE, M. B. SPORN & A. B. ROBERTS. 1994. Maternal rescue of transforming growth factor-β1 null mice. Science 264: 1936-1938.
12. LYONS, K. M., B. L. M. HOGAN & E. J. ROBERTSON. 1995. Colocalization of Bmp 7 and Bmp 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development. Mech. Dev. 50: 71-83.
13. LYONS, K. M., R. W. PELTON & B. L. M. HOGAN. 1990. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for Bone Morphogenetic Protein-2A (BMP-2A). Development 109: 833-844.
14. LYONS, K. M., R. W. PELTON & B. L. M. HOGAN. 1989. Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-β-like genes coordinately regulate aspects of embryonic development. Genes Dev. 3: 1657-1668.
15. PARR, B. A. & A. P. MCMAHON. 1994. Wnt genes and vertebrate development. Curr. Opin. Genet. Dev. 4: 523-528.
16. SAZEN, L. 1987. Organogenesis of the Kidney. Cambridge Univ. Press. Cambridge, England.
17. SHUBIN, N. H. & P. ALBRERCH. 1986. A morphogenetic approach to the origin and basic organization of the tetrapod limb. Evol. Biol. 20: 319-387.
18. STARK, K., S. VAINIO, G. VASSILEVA & A. P. MCMAHON. 1994. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372: 679-683.
19. STORM, E. E., T. V. HUYNH, N. G. COPELAND, N. A. JENKINS, D. M. KINGSLEY & S.-L. LEE. 1994. Limb alterations in brachypodism mice due to mutations in a new member of the TGF-β superfamily. Nature 368: 639-643.
20. WOZNEY, J. M., V. ROSEN, A. J. CELESTE, L. M. MITSOCK, M. J. WHITTERS, R. W. KRIZ, R. M. HEWICK & E. A. WANG. 1988. Novel regulators of bone formation: Molecular clones and activities. Science 242: 1528-1534.
21. ZHANG, H. & A. BRADLEY. 1995. Mice deficient in BMP-2 are nonviable and have defects in amnion/chorion and cardiac development. Submitted.