Use dependence of tetrodotoxin block of sodium channels: A revival of the trapped-ion mechanism

Biophysical Journal

Volumn 71, Issue 3, 1996, Pages 1295-1312

  Conti, Franco ^a   Gheri, Alessandra ^a   Pusch, Michael ^a,b   Moran, Oscar ^a  

^a CNR   (Italy)

^b UNIVERSITY OF HAMBURG   (Germany)

Author keywords

The use dependent block of sodium channels by tetrodotoxin (TTX) has been studied in cRNA injected Xenopus oocytes expressing the subunit of rat brain IIA channels. The kinetics of stimulus induced extra block are consistent with an underlyin

Indexed keywords

SODIUM CHANNEL; TETRODOTOXIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CHANNEL GATING; DATA ANALYSIS; EXTRACELLULAR CALCIUM; GENE EXPRESSION; MEMBRANE STABILIZATION; NONHUMAN; RAT; RNA ANALYSIS; XENOPUS;

ANIMALIA;

EID: 0029741451     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(96)79330-X     Document Type: Article

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