Mutation of isoleucine 747 by a threonine alters the ligand responsiveness of the human glucocorticoid receptor

Molecular Endocrinology

Volumn 10, Issue 10, 1996, Pages 1214-1226

  Roux, Sylvie ^a   Térouanne, Béatrice ^a   Balaguer, Patrick ^a   Jausons Loffreda, Nathalie ^a   Pons, Michel ^a   Chambon, Pierre ^b   Gronemeyer, Hinrich ^b   Nicolas, Jean Claude ^a  

^a INSERM   (France)

^b INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; ISOLEUCINE; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; GENE MUTATION; HORMONE RECEPTOR INTERACTION; HUMAN; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; COS CELLS; HUMANS; ISOLEUCINE; LIGANDS; MOLECULAR SEQUENCE DATA; POINT MUTATION; RADIOLIGAND ASSAY; RECEPTORS, GLUCOCORTICOID; THREONINE;

ANIMALIA;

EID: 0029740829     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.10.10.1214     Document Type: Article

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