Selective colocalization of lipid peroxidation and protein thiol loss in chemically induced hepatic preneoplastic lesions: The role of γ-glutamyltranspeptidase activity

Histochemistry and Cell Biology

Volumn 106, Issue 3, 1996, Pages 275-282

  Pompella, Alfonso ^a   Paolicchi, Aldo ^b   Dominici, Silvia ^a   Comporti, Mario ^a   Tongiani, Roberto ^b  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DIETHYLNITROSAMINE; GAMMA GLUTAMYLTRANSFERASE; THIOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; HISTOCHEMISTRY; LIPID PEROXIDATION; LIVER CANCER; MALE; NONHUMAN; PRECANCER; PRIORITY JOURNAL; RAT;

EID: 0029740522     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02473237     Document Type: Article

References (45)

1. Allen RG, Balin AK (1989) Oxidative influence on development and differentiation: an overview of a free radical theory of development. Free Radic Biol Med 6:631-661
2. Atzori L, Dypbukt JM, Sundquist K, Cotgreave I, Edman CC, Moldéus P, Grafström RC (1990) Growth-associated modifications of low-molecular-weight thiols and protein sulfhydryls in human bronchial fibroblasts. J Cell Physiol 143:165-171
3. Bartoli GM, Bartoli S, Galeotti T, Bertoli E (1980) Superoxide dismutase content and microsomal lipid composition of tumours with different growth rates. Biochim Biophys Acta 620: 205-211
4. Benedetti A, Malvaldi G, Fulceri R, Comporti M (1984) Loss of lipid peroxidation as a histochemical marker for preneoplastic hepatocellular foci of rats. Cancer Res 44:5712-5717
5. Cameron R, Kellen J, Malkin A, Farber E (1978) γ-Glutamyltransferase in putative premalignant liver cell populations during hepatocarcinogenesis. Cancer Res 38:823-829
6. Canonero R, Martelli A, Marinari UM, Brambilla G (1990) Mutation induction in Chinese hamster lung V79 cells by five alk-2-enals produced by lipid peroxidation. Mutat Res 244:153-156
7. Casini AF, Maellaro E, Pompella A, Ferrali M, Comporti M (1987) Lipid peroxitation, protein thiols and calcium homeostasis in bromobenzene-induced liver damage. Biochem Pharmacol 36:3689-3695
8. Cerutti PA (1985) Prooxidant states and tumor promotion. Science 227:375-381
9. Chang M, Shi M, Forman HJ (1992) Exogenous glutathione protects endothelial cells from menadione toxicity. Am J Physiol 6:L634-L637
10. Chung F-L, Chen H-JC, Guttenplan JB, Nishikawa A, Hard GC (1993) 2,3-Epoxy-4-hydroxynonanal as a potential tumor-initiating agent of lipid peroxidation. Carcinogenesis 14:2073-2077
11. Dean RT, Gieseg S, Davies MJ (1993) Reactive species and their accumulation on radical-damaged proteins. Trends Biochem Sci 18:437-441
12. Dianzani MU (1993) Lipid peroxidation and cancer. Crit Rev Oncol Hematol 15:125-147
13. Di Monte D, Ross D, Bellomo G, Eklow L, Orrenius S (1984) Alterations in intracellular thiol homeostasis during the metabolism of menadione by isolated rat hepatocytes. Arch Biochem Biophys 235:334-342
14. Enomoto K, Farber E (1982) Kinetics of phenotypic maturation of remodeling of hyperplastic nodules during liver carcinogenesis. Cancer Res 42:2330-2335
15. Esterbauer H, Eckl P, Ortner A (1990) Possible mutagens derived from lipids and lipid precursors. Mutat Res 238:223-233
16. Esterbauer H, Schaur RJ, Zollner H (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11:81-128
17. Farber E (1990) Clonal adaptation during carcinogenesis. Biochem Pharmacol 39:1837-1846
18. Gonzalez MJ, Schemmel RA, Gray JI, Dugan L jr, Sheffield LG, Welsch CW (1991) Effect of dietary fat on growth of MCF-7 and MDA-MB231 human breast carcinomas in athymic nude mice: relationship between carcinoma growth and lipid peroxidation product levels. Carcinogenesis 12:1231-1235
19. Greenley TL, Davies MJ (1994) Direct detection of radical generation in rat liver nuclei on treatment with tumour-promoting hydroperoxides and related compounds. Biochim Biophys Acta 1226:56-64
20. Hanigan MH, Pitot HC (1985) Gammu-glutamyltranspeptidase - its role in hepatocarcinogenesis. Carcinogenesis 6:165-172
21. Hanigan MH, Ricketts WA (1993) Extracellular glutathione is a source of cysteine for cells that express γ-glutamyltranspeptidase. Biochemistry 32:6302-6306
22. Kalengayi MM, Ronchi G, Desmet VJ (1975) Gamma-glutamyltranspeptidase in rat liver during atlatoxin B1 induced carcinogenesis. J Natl Cancer Inst 55:579-588
23. Kyle ME, Nakae D, Sakaida I, Serroni A, Farber JL (1989) Protein thiol depletion and the killing of cultured hepatocytes by hydrogen peroxide. Biochem Pharmacol 38:3797-3805
24. Masotti L, Casali E, Galeotti T (1988a) Lipid peroxidation in tumour cells. Free Radic Biol Med 4:377-386
25. Masotti L, Casali E, Gesmundo N, Sartor G, Galeotti T, Borrello S, Piretti MV, Pagliuca G (1988b) Lipid peroxidation in cancer cells: chemical and physical studies. Ann NY Acad Sci 551: 47-58
26. Minotti G, Borrello S, Palombini G, Galeotti T (1986) Cytochrome P-450 deficiency and resistance to t-butyl hydroperoxide of hepatoma microsomal lipid peroxidation. Biochim Biophys Acta 876:220-225
27. Nöhammer G (1982) Quantitative microspectrophotometrical determination of protein thiols and disulfides with 2,2′-dihydroxy-6,6′-dinaphthyldisulfide (DDD). Histochemistry 75: 219-250
28. Nöhammer G (1989) Histochemical demonstration of primary amino groups with 2-hydroxy-1-naphthaldehyde (HNA): optimization of the method. Acta Histochem 86:167-176
29. O'Brian CA, Ward NE, Weinstein IB, Bull AW, Marnett LJ (1988) Activation of rat brain protein kinase C by lipid oxidation products. Biochem Biophys Res Commun 155:1374-1380
30. Pompella A, Comporti M (1991) The use of 3-hydroxy-2-naphthoic acid hydrazide and Fast Blue B for the histochemical detection of lipid peroxidation in animal tissues - a microphotometric study. Histochemistry 95:255-262
31. Pompella A, Maellaro E, Casini AF, Ferrali M, Ciccoli L, Comporti M (1987) Measurement of lipid peroxidation in vivo: a comparison of different procedures. Lipids 22:206-211
32. Pompella A, Romani A, Benedetti A, Comporti M (1991) Loss of membrane protein thiols and lipid peroxidation in allyl alcohol hepatotoxicity. Biochem Pharmacol 41:1255-1259
33. Rajpert-De Meyts E, Shi M, Chang M, Robison TW, Groffen J, Heisterkamp N, Forman HJ (1992) Trunsfection with γ-glutamyltranspeptidase enhances recovery from glutathione depletion using extracellular glutathione. Toxicol Appl Pharmacol 114:56-62
34. Rutenburg AM, Kim H, Fischbein JW, Hanker JS, Wasserkrug HL, Seligman AM (1969) Histochemical and ultrastructural demonstration of γ-glutamyltranspeptidase activity. J Histochem Cytochem 17:517-526
35. Schaich KM (1992) Metals and lipid oxidation. Contemporary issues. Lipids 27:209-218
36. Schauenstein E, Gölles J, Waltersdorfer H, Schaur RJ (1978) Association between the doubling time of various cells and tissues, and the SH-content of their soluble proteins. Z Naturforsch [C] 33:79-83
37. Schaur RJ, Winkler P, Hayn M, Schauenstein E (1987) Decrease of glutathione and fatty acids during iron-induced lipid peroxidation in Ehrlich ascites tumour cells. Monatsschr Chemie 118:823-830
38. 2-induced injury by 2,3-dimethoxy-1,4-naphthoquinone. Free Radic Biol Med 15:57-67
39. Solt D, Farber E (1976) New principle for the analysis of chemical carcinogenesis. Nature 263:701-706
40. Stark A-A, Zeiger E, Pagano DA (1993) Glutathione metabolism by γ-glutamyltranspeptidase leads to lipid peroxidation: characterization of the system and relevance to hepatocarcinogenesis. Carcinogenesis 14:183-189
41. Stark A-A, Russell JJ, Langenbach R, Pagano DA, Zeiger E, Huberman E (1994) Localization of oxidative damage by a glutathione-γ-glutamyltranspeptidase system in preneoplastic lesions in sections of livers from carcinogen-treated rats. Carcinogenesis 15:343-348
42. Sun Y (1990) Free radicals, antioxidant enzymes and carcinogenesis. Free Radic Biol Med 8:583-599
43. Tien M, Bucher JR, Aust SD (1982) Thiol-dependent lipid peroxidation. Biochem Biophys Res Commun 107:279-285
44. Wiseman H, Halliwell B (1993) Carcinogenic antioxidants - diethylstilboestro), hexoestrol and 17-α-ethynyloestradiol. FEBS Lett 332:1-2
45. Zhang J-R, Sevanian A (1993) The genotoxic effects of arachidonic acid in V79 cells are mediated by peroxidation products. Toxicol Appl Pharmacol 121:193-202