Functional expression of CD11a on CD8+ cells is suppressed in regional lymph nodes with cancer involvement in patients with gastrointestinal carcinoma

Cancer

Volumn 78, Issue 8, 1996, Pages 1677-1685

  Shinkai, Hiroshi ^a   Kitayama, Joji ^a   Kimura, Wataru ^a   Muto, Tetsuichiro ^a   Shibata, Yohichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

CD11a (LFA 1); CD8+ cells; gastrointestinal carcinoma; regional lymph nodes

Indexed keywords

BETA1 INTEGRIN; CD16 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CELL ADHESION MOLECULE; HERMES ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ADULT; AGED; ARTICLE; CANCER CELL; CELL ADHESION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL CARCINOMA; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; MALE; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; FEMALE; FLOW CYTOMETRY; GASTROINTESTINAL NEOPLASMS; HUMANS; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; LYMPHOCYTE SUBSETS; MALE; MIDDLE AGED; PHENOTYPE;

EID: 0029740425     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0142(19961015)78:8<1677::AID-CNCR7>3.0.CO;2-B     Document Type: Article

References (43)

1. Fisher B, Fisher ER. Studies concerning the regional lymph node in cancer. I. Initiation of immunity. Cancer 1971; 27:1001-4.
2. Fisher B, Fisher ER. Studies concerning the regional lymph node in cancer: II. Maintenance of immunity. Cancer 1972;29:1496-501.
3. Fisher B, Saffer EA, Fisher ER. Studies concerning the regional lymph node in cancer. III. Response of regional lymph node cells from breast and colon cancer patients to PHA stimulation. Cancer 1972;30:1202-15.
4. Fisher B, Saffer E, Fisher ER. Studies concerning the regional lymph node in cancer. IV. Tumor inhibition by regional lymph node cells. Cancer 1974;33:631-6.
5. Goldfarb PM, Hardy MA. The immunologic responsiveness of regional lymphocytes in experimental cancer. Cancer 1975;35:778-83.
6. Fisher B, Montague E, Redmond C, Barton B, Borland D, Fisher ER, et al. Comparison of radical mastectomy with alternative treatments for primary breast cancer: a first report of results from a prospective randomized clinical trial. Cancer 1977;39:2827-39.
7. Veronesi U, Adamus J, Bandiera DC, Brennhovd IO, Caceres E, Cascinelli N, et al. Inefficacy of immediate node dissection in stage 1 melanoma of the limbs. N Engl J Med 1977;297:627-30.
8. Crile G Jr. Rationale of simple mastectomy without radiation for clinical stage 1 cancer of the breast. Surg Gynecol Obstet 1965;120:975-82.
9. Papaioannou A. The contribution of regional lymph nodes in the resistance against breast cancer: practical implications. J Surg Oncol 1984;25:232-9.
10. Vose BM, Vánkey F, Argov S, Klein E. Natural cytotoxicity in man: activity of lymph node and tumor-infiltrating lymphocytes. Eur J Immunol 1977;7:753-7.
11. Moore M, Vose BM. Extravascular natural cytotoxicity in man: anti-K562 activity of lymph-node and tumor-infiltrating lymphocytes. Int J Cancer 1981;27:265-72.
12. Nakamura H, Ishiguro K, Mori T. Different immune functions of peripheral blood, regional lymph node, and tumor infiltrating lymphocytes in lung cancer patients. Cancer 1988;62:2489-97.
13. Mickel RA, Kessler DJ, Taylor JMG, Lichtenstein A. Natural killer cell cytotoxicity in the peripheral blood, cervical lymph nodes, and tumor of head and neck cancer patients. Cancer Res 1988;48:5017-22.
14. Whitford P, Alam SM, George WD, Campbell AM. Flow cytometric analysis of tumour-draining lymph nodes in breast cancer patients. Eur J Cancer 1992;28:350-6.
15. Rubbert A, Manger B, Lang N, Kalden JR, Platzer E. Functional characterization of tumor-infiltrating lymphocytes, lymph-node lymphocytes and peripheral-blood lympho cytes from patients with breast cancer. Int J Cancer 1991;49:25-31.
16. Reeves ME. A metastatic tumor cell line has greatly reduced levels of a specific homotypic cell adhesion molecule activity. Cancer Res 1992;52:1546-52.
17. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, et al. E-Cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991;113:173-85.
18. Kinsella AR, Green B, Lepts GC, Hill CL, Bowie G, Taylor BA. The role of the cell-cell adhesion molecule E-cadherin in large bowel tumour cell invasion and metastasis. Br J Cancer 1993;67:904-9.
19. Oka H, Shiozaki H, Kobayashi K, Inoue M, Tahara H, Kobayashi T, et al. Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 1993;53:1696-701.
20. Stein B, Momburg F, Schwarz V, Schlag P, Moldenhauer G, Moller P. Reduction or loss of HLA-A, -B, -C antigens in colorectal carcinoma appears not to influence survival. Br J Cancer 1988;57:364-8.
21. Bernards R, Dessain SK, Weinberg RA. N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma. Cell 1986;47:667-74.
22. Chen FA, Repasky EA, Bankert RB. Human lung tumor-associated antigen identified as an extracellular matrix adhesion molecule. J Exp Med 1991;173:1111-9.
23. Rudy W, Hofmann M, Schwartz-Albiez R, Zöller M, Heider K-H, Ponta H, et al. The two major CD44 proteins expressed on a metastatic rat tumor cell line are derived from different splice variants: each one individually suffices to confer metastatic behavior. Cancer Res 1993;53:1262-8.
24. Günhert U, Hofmann M, Rudy W, Reber S, Zöller M, Haubmann I, et al. A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 1991;65:13-24.
25. Arch R, Wirth K, Hofmann M, Ponta H, Matzku S, Herrlich P, et al. Participation in normal immune responses of a metastasis-inducing splice variant of CD44. Science 1992;257:682-5.
26. Miltenyi S, Müller W, Weichel W, Radbruch A. High gradient magnetic cell separation with MACS. Cytometry 1990;11:231-8.
27. Bruning JW, Kardol MJ, Arentzen R. Carboxyl fluorescein fluorchromasia analysis, I. Non-radioactively labeled cell mediated lympholysis. J Immunol Methods 1980;33:33-44.
28. Gjörloff A, Dahlenborg K, Björklund M, Hedlund G, Kalland T, Sjögren H-O, et al. Monocyte-regulated IFN-γ production in human T cell involves CD2 signaling. J Immunol 1993;151:1328-36.
29. Hasler T, Albrecht GR, van Schravendijk MR, Aguiar JC, Morehead KE, Pasloske BL, et al. An improved microassay for Plasmodium Falciparum cytoadherence using stable transformants of Chinese hamster ovary cells expressing CD36 or intercellular adhesion molecule-1. Am J Trop Med Hyg 1993;48:332-47.
30. Rothlein R, Dustin ML, Marlin SD, Springer TA. A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J Immunol 1986;137:1270-4.
31. Staunton DE, Dustin ML, Springer TA. Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1. Nature 1989;339:61-4.
32. van Epps DE, Potter J, Vachula M, Smith CW, Anderson DC. Suppression of human lymphocyte chemotaxis and transendothelial migration by anti-LFA-1 antibody. J Immunol 1989;143:3207-10.
33. Oppenheimer-Marks N, Davis LS, Lipsky PE. Human T lymphocyte adhesion to endothelial cells and transendothelial migration. Alteration of receptor use relates to the activation status of both the T cell and the endothelial cell. J Immunol 1990;145:140-8.
34. Kitayama J, Juji T, Atomi Y, Kuroda A, Muto T, Kobayashi M, et al. Transendothelial migration activity of Lymphokine-Activated Killer (LAK) cells. J Immunol 1993;151:1663-72.
35. Greene WC, Fleisher TA, Waldmann TA. Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor of T cell proliferation. J Immunol 1981;126:1185-91.
36. Roth JA, Grimm EA, Gupta RK, Ames RS. Immunoregulatory factors derived from human tumors: I. Immunologic and biochemical characterization of factors that suppress lymphocyte proliferative and cytotoxic responses in vitro. J Immunol 1982;128:1955-62.
37. Kehrl JH, Wakefield LM, Roberts AB, Jakowlew S, Alvarez-Mon M, Derynck R, et al. Production of transforming growth factor β by human T lymphocytes and its potential role in the regulation of T cell growth. J Exp Med 1986;163:1037-50.
38. Lee G, Ellingsworth LR, Gillis S, Wall R, Kincade PW. β transforming growth factors are potential regulators of B lymphopoiesis. J Exp Med 1987;166:1290-9.
39. Rook AH, Kehrl JH, Wakefield LM, Roberts AB, Sporn MB, Burlington DB, et al. Effects of transforming growth factor β on the functions of natural killer cells: depressed cytolytic activity and blunting of Interferon responsiveness. J Immunol 1986;136:3916-20.
40. Tsunawaki S, Sporn M, Ding A, Nathan C. Deactivation of macrophages by transforming growth factor-β. Nature 1988;334:260-2.
41. Tada T, Ohzeki S, Utsumi K, Takiuchi H, Muramatsu M, Li X-F, et al. Transforming growth factor-β-induced inhibition of T cell function: susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state. J Immunol 1991;146:1077-82.
42. Cerwenka A, Bevec D, Majdic O, Knapp W, Holter W. TGF-β1 is a potent inducer of human effector T cell. J Immunol 1994;153:4367-77.
43. Tsujisaki M, Imai K, Hirata H, Hanzawa Y, Masuya J, Nakano T, et al. Detection of circulating intercellular adhesion molecule-1 antigen in malignant diseases. Clin Exp Immunol 1991;85:3-8.