Effects of chronic treatment of rat with ethinyl estradiol on the sensitivity of isolated vascular preparations to nor-adrenaline

Indian Journal of Pharmacology

Volumn 28, Issue 2, 1996, Pages 113-115

  Bhatt, J D ^a   Gulati, O D ^a  

^a Baroda Medical College   (India)

Author keywords

aortic strip; Ethinyl estradiol; nor adrenaline; portal vein of rats

Indexed keywords

ESTRADIOL; NORADRENALIN;

ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL TONE; DOSE TIME EFFECT RELATION; DRUG EFFECT; LONG TERM EXPOSURE; MALE; NONHUMAN; PORTAL VEIN; RAT;

EID: 0029740308     PISSN: 02537613     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Bhatt JD, Gulati OD. The role of the sympathetic nervous system in oestrogen-induced hypertension in rats. Br J Pharmacol 1986;89:685-91.
2. Colucci WS, Cimbrone MA Jr., McLaughin MK, Halpern W, Alexander RW. Increased vascular catecholamine sensitivity and alpha- adrenergic receptor affinity in female and estrogen-treated mate rats. Cir Res 1982;50:805-11.
3. Altura BM. Sex as a factor influencing the responsiveness of arterioles to catecholamine. Eur J Pharmacol 1972;20: 261-5.
4. Rorie KD, Muldon SM. Effect of progesterone and estrogen on the reactivity of isolated blood vessels. Circulation 1976;53, 54:II-42.
5. Hodgson BJ, Dumas S, Bolling DR, Heesch GM. Effect of estrogen on sensitivity of rabbit bladder and urethra to phenylephrine. Invest Urol 1978;16:67-9.
6. Roberts JH, Insel BA, Goldfien A. Alpha-adrenoceptors but not beta-adrenoceptors increase in rabbit uterus with estrogen. Nature 1977;270:624-5.
7. Ichida S, Oda Y, Tokunda H, Hiyashi T, Murakami T, Kita T. Mechanisms of specific changes by estradiol in sensitivity of rat uterus to serotonin. J Pharmacol Exp Ther 1984; 229:244-9.
8. Bhatt JD, Gulati OD. Effects of chronic ethinyl estradiol treatment on the sensitivity of isolated rat vas deferens to various agonists. Ind J Pharmacol 1990;22:78-84.
9. Vanhoutte PM. Calcium entry blockers and vascular smooth muscle. Circulation 1982;65:11-9.
10. Krishnamurty VSR. The role of calcium ion in mechanical contractile response of vascular smooth muscle of rat. 1974 Ph.D. Thesis, The M.S. University of Baroda, Baroda, India.
11. Shibata S, Kurahoshi K, Kuchii M. A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats. J Pharmacol Exp Ther 1973;185:406-17.
12. Hall Back M, Lundgreen Y, Weiss L. Reactivity to noradrenaline of aortic strip and portal vein from spontaneously hypertensive and normotensive rats. Acta Physiol Scand 1971;81:176-81.
13. Cohen ML, Berkowitz BA. Decreased vascular relaxation in hypertension. J Pharmacol Exp Ther 1976;193:396-406.
14. Triner L, Vullirmoz Y, Verosky M, Manager WM. Cyclic adenosine monophosphate and vascular reactivity in spontaneously hypertensive rats. Biochem Pharmacol 1975;24: 743-5.
15. Peiper U, Klemt P, Popov R. The contractility of venous vascular smooth muscles in spontaneously hypertensive or renal hypertensive rats. Basic Res Cardiol 1979;74: 21-34.
16. Harris A, Swamy VC, Trigle DJ, Waters DH. Responses to noradrenaline of portal vein strips from normotensive and spontaneously hypertensive rats. J Auto Pharmacol 1980;1:61-6.
17. Bevan RD, Purdy RE, Su C, Bevan JA. Evidence for an increase in adrenergic nerve function in blood vessels from experimental hypertensive rabbit. Cir Res 1975;503-8.
18. Patil PN, Fudge K, Jacobwitz D. Steric aspects of adrenergic drugs XVIII, alpha-adrenergic receptors of mammalian aorta. Eur J Pharmacol 1972;19:79-87.
19. Aalkjaer C, Mulvany MJ. Morphological and mechanical properties of small mesenteric arteries and veins in spontaneously hypertensive rats. Acta Physiol Scand 1979; 309-12.